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Quantum public-key crypto via EPR pairs

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 58-63页

作者： Xiang-Qun Fu Hong-Wei Li Jian-Hong Shi Tan Li Wan-Su Bao Henan Key Laboratory of Quantum Information and Cryptography Information Engineering University Synergetic innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China

With the development of quantum computing technology, quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key cryptography. This paper designs a quantum trapdoor one-way function via EPR pairs and quantum measurements. Based on this, a new quantum public-key cryptosystem is presented, which offers forward security,and can resist the chosen-plaintext attack and chosen-ciphertext attack. Compared with the existing quantum public-key cryptos,eavesdropping can be automatically detected in this new quantum public-key cryptosystem under a necessary condition, which is also detailed in the paper.

关键词： quantum public-key crypto trapdoor one-way function EPR pairs

Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo

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World Journal of Gastroenterology 2009年第22期15卷 2754-2762页

作者： Michael A van Geer Conny T Bakker Naoya Koizumi Hiroyuki Mizuguchi John G Wesseling Ronald PJ Oude Elferink Piter J Bosma Liver Center of the academic Medical Center of the University of Amsterdam Laboratory of Gene Transfer and Regulation National Institute of Biomedical Innovation

AIM:To generate an adenoviral vector specifically targeting the EphA2 receptor(EphA2R) highly expressed on pancreatic cancer cells in ***:YSA,a small peptide ligand that binds the EphA2R with high affinity,was inserted into the HI loop of the adenovirus serotype 5 fiber *** further increase the specificity of this vector,binding sites for native adenoviral receptors,the coxsackie and adenovirus receptor(CAR) and integrin,were ablated from the viral *** ablated retargeted adenoviral vector was produced on 293T *** c targeting of this novel adenoviral vector to pancreatic cancer was investigated on established human pancreatic cancer cell *** demonstrating specifi c in vitro targeting,in vivo targeting to subcutaneous growing human pancreatic cancer was tested by intravenous and intraperitoneal administration of the ablated adenoviral ***:Ablation of native cellular binding sites reduced adenoviral transduction at least *** of the YSA peptide in the HI loop restored adenoviral transduction of EphA2R-expressing cells but not of cells lacking this ***-mediated transduction was inhibited by addition of synthetic YSA *** transduction specificity of the ablated retargeted vector towards human pancreatic cancer cells was enhanced almost 10-fold in *** a subsequent in vivo study in a nude(nu/nu) mouse model however,no increased adenoviral targeting to subcutaneously growing human pancreas cancer nodules was seen upon injection into the tail vein,nor upon injection into the ***:Targeting the EphA2 receptor increases specificity of adenoviral transduction of human pancreatic cancer cells in vitro but fails to enhance pancreatic cancer transduction in vivo.

关键词： Pancreatic cancer Adenoviruses Ephrin A receptor Targeting Genetic transduction

Targeting the PI3K/AKT/mTOR pathway in epithelial ovarian cancer,therapeutic treatment options for platinum-resistant ovarian cancer

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Cancer Drug Resistance 2021年第3期4卷 573-595页

作者： Natasha Rinne Elizabeth LChristie Anastasia Ardasheva Chun Hei Kwok Nikita Demchenko Caroline Low Catherine Tralau-Stewart Christina Fotopoulou Paula Cunnea Department of Surgery&Cancer Imperial College LondonHammersmith campusLondon W120NNUK Peter MacCallum Cancer Centre East MelbourneVictoria 3002Australia Department of Metabolism Digestion&Reproduction Imperial College LondonLondon W120NNUK takeda academic innovation Center for External InnovationTakeda CaliforniaSan DiegoCA 92121USA

The survival rates for women with ovarian cancer have shown scant improvement in recent years,with a 5-year survival rate of less than 40%for women diagnosed with advanced ovarian ***-grade serous ovarian cancer(HGSOC)is the most lethal subtype where the majority of women develop recurrent disease and chemotherapy resistance,despite over 70%-80%of patients initially responding to platinum-based *** phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)/mammalian target of rapamycin(mTOR)signaling pathway regulates many vital processes such as cell growth,survival and ***,this pathway is frequently dysregulated in cancers including different subtypes of ovarian cancer,through amplification or somatic mutations of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha(PIK3CA),amplification of AKT isoforms,or deletion or inactivation of *** evidence indicates a role for the PI3K/AKT/mTOR pathway in the development of chemotherapy resistance in ovarian ***,targeting key nodes of the PI3K/AKT/mTOR pathway is a potential therapeutic *** this review,we outline dysregulation of PI3K signaling in ovarian cancer,with a particular emphasis on HGSOC and platinum-resistant *** review pre-clinical evidence for inhibitors of the main components of the PI3K pathway and highlight past,current and upcoming trials in ovarian cancers for different inhibitors of the *** no inhibitors of the PI3K/AKT/mTOR pathway have thus far advanced to the clinic for the treatment of ovarian cancer,several promising compounds which have the potential to restore platinum sensitivity and improve clinical outcomes for patients are under evaluation and in various phases of clinical trials.

关键词： Ovarian cancer high-grade serous PI3K/AKT/mTOR pathway chemotherapy resistance inhibitors therapeutics

Smart Cellulose‑Based Janus Fabrics with Switchable Liquid Transportation for Personal Moisture and Thermal Management

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Nano-Micro Letters 2025年第1期17卷 333-347页

作者： Jianfeng Xi Yanling Lou Liucheng Meng Chao Deng Youlu Chu Zhaoyang Xu Huining Xiao Weibing Wu Jiangsu Co‑innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsJiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass MaterialsNanjing Forestry UniversityNanjing 210037People’s Republic of China College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada Macromolecular Chemistry and Bavarian Polymer Institute University of BayreuthBayreuth 95440Germany

The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human ***,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a ***,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/*** cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport ***,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability *** fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too *** addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic *** smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.

关键词： Directional water transport Cotton fabric Anti-gravity directional liquid transportation Janus wettability

Ramp-Wave Compression Experiment with Direct Laser Illumination on ShenGuang-Ⅲ Prototype Laser Facility

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Chinese Physics Letters 2017年第3期34卷 82-85页

作者：王峰薛全喜纪腾理玉龙徐涛彭晓世 Research Center of Laser Fusion China Academic of Engineering and Physics Collaborative innovation Center of IFSA Shanghai Jiao Tong University State Key Laboratory of Laser Interaction with Matter and Northwest Institute of Nuclear Technology

Ramp-wave compression experiment to balance the high compression pressure generation in aluminum and x-ray blanking effect in transparent window is demonstrated with an imaging velocity interferometer system for any reflector （VISAR） on ShenGuang-Ⅲprototype laser facility. The highest pressure is about 500 GPa after using the multilayer target design Al/Au/Al/LiF and -10^13 W//cm2 laser pulse illuminated on the planar Al target, which generates the spatial uniformity to 〈1% over 500 μm on the ablation layer. A 2-μm-thick Au layer is used to prevent the x-ray from preheating the planar ablation Al layer and window material LiF. The imaging VISAR system can be used to record the abrupt loss of the probe beam （λ= 532 nm） caused by absorption and reflection of 20-μm, 30-μm and 40-μm-thick Al, i.e., the blanking effect. Although there are slight shocks in the target, the peak pressure 500 GPa, which is the highest data up to now, is obtained with ramp-wave compression.

关键词： VISAR LiF Prototype Laser Facility Ramp-Wave Compression Experiment with Direct Laser Illumination on ShenGuang RWC Al

ENABLING TECHNOLOGIES FOR BEYOND TD-LTE-ADVANCED AND 5G WIRELESS COMMUNICATIONS

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China Communications 2016年第6期13卷 I0001-I0002页

作者： Shanzhi Chen Ping Zhang Rahim Tafazoili Datang Telecom Technology&Industry Group BUPT academic board State Key Lab of Networking and Switching Technology ics(formerly known as ccsr) 5g innovation centre at the university of surrey UK

TD-LTE-Advanced was accepted as one of the 4G global standards by ITU in *** 2013,Chinese government issued 4G TD-LTE licenses to all 3 Chinese ***,more than 1/3 of the global 4G equipments and users are using TD-LTE-Advanced ***,research toward 5G is one of the most attractive topics of mobile communication *** 3GPP has launched several workshops to

关键词：无线通信技术中国政府国际标准 4G ITU 运营商 LTE

Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu Yue Li Hua Zhang Lian-Lian Wang Wen-Wen Liu Xin Yang Ming-Zhao Xiao Hao-Ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

Evolutionary innovations of the vertebrates

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Integrative Zoology 2007年第2期2卷 60-67页

作者： Oded KHANER Department of Health Sciences Hadassah Academic CollegeJerusalemIsrael

This review concentrates on the greatest anatomical and morphological evolutionary innovations of the *** evolution,many new species of vertebrates evolved and underwent modifications by developing new forms,structures and functions of tissues and organ *** development of the chordates and vertebrates is herein examined in terms of innovations in their organ systems and organismal *** during chordate and vertebrate evolutionary history with unusually high rates of increase in morphological complexity are *** increases in complexity in particular chordates and vertebrates coincided with a likely genome duplication event,which resulted in a large increase in genome size and gene number in early vertebrates,and might indicate an increase in *** Hox and Pax gene families are also discussed because both illustrate the relationships between organismal and molecular *** unique innovations of vertebrates caused major changes in their organismal complexity,and these changes provided new options for future evolutionary development.

关键词： evolutionary development gene family organismal complexity vertebrate innovation

Synergistic catalytic removals of NO,CO and HC over CeO_2 modified Mn-Mo-W-O_x/TiO_2-SiO_2 catalyst

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Journal of Rare Earths 2018年第2期36卷 148-155页

作者： Qijie Jin Yuesong Shen Guorong Sui Xingjun Tao Youchun Pan Shemin Zhu Jiangsu National Synergetic innovation Center for Advanced Materials (SICAM) Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites College of Materials Science and Engineering Nanjing Tech University

A series of Mn-Mo-W-O_x/TiO_2-SiO_2 catalysts was modified with CeO_2 using an extrusion molding method. The catalytic activities of the obtained catalysts were tested for the synergistic catalytic removals of CO, NO and C_3H_8. The ratio of catalyst composition on catalytic activities for NH_3-SCR was optimized, which reveals that the molar ratio of Ti/Si was 9：1 and the catalyst containing 1.5 wt% CeO_2 and 12 wt% Mn-Mo-W-O_x exhibits the best catalytic performances. These samples were characterized by XRD, N_2-BET, Py-IR, NH_3-TPD, SEM/element mapping, H_2-TPR and XPS, respectively. Results show that the optimal catalyst exhibits more than 99% NO conversion, 86% CO conversion and 100% C_3H_8 conversion under GHSV of 5000 h^（-1）. In addition, the GHSV has little influence on removal of NO when it is less than 15,000 h^（-1）. Furthermore, the addition of CeO_2 will enhance the surface acidity, increase Mn^（4＋）concentration and inhibit the grain growth, which are favorable for the excellent catalytic ***,the 1.5 wt% CeO_2-12 wt% Mn-Mo-W-O_x/TiO_2-SiO_2 possesses outstanding redox properties,abundant acid sites and high Mn^（4＋） concentration, which provide a guarantee for synergistic catalytic removal of CO, NO and HC.

关键词： Mn-Mo-W-Ox/TiO2-SiO2 Cerium oxide additive Synergistic catalytic removal Nitrogen oxide Rare earths