检索结果-南通市图书馆

Impact of exercise on markers of B cell-related immunity:A systematic review

Journal of Sport and Health Science 2024年第3期13卷 339-352,I0002页

作者： David Walzik Sergen Belen Karen Wilisch Marie Kupjetz Silvana Kirschke Tobias Esser Niklas Joisten Alexander Schenk Sebastian Proschinger Philipp Zimmer Division of Performance and Health(Sports Medicine) Institute for Sport and Sport ScienceTU Dortmund UniversityDortmund 44227Germany

Background:B cells represent a crucial component of adaptive immunity that ensures long-term protection from infection by generating pathogen-specific immunoglobulins.Exercise alters B cell counts and immunoglobulin levels,but evidence-based conclusions on potential benefits for adaptive immunity are lacking.This systematic review assessed current literatures on the impact of acute exercise and exercise training on B cells,immunoglobulins,and markers of secretory immunity in human biofluids.Methods:According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)guidelines,MEDLINE,Web of Science,and Embase were searched on March 8,2023.Non-randomized controlled trials and crossover trials investigating the impact of acute exercise or exercise training on B cell counts and proportions,immunoglobulin levels,salivary flow rate,or secretory immunoglobulin A secretion rate were included.Quality and reporting of exercise training studies were assessed using the Tool for the Assessment of Study Quality and reporting in Exercise.Study characteristics,outcome measures,and statistically significant changes were summarized tabularly.Results:Of the 67 eligible studies,22 applied acute exercise and 45 applied exercise training.All included outcomes revealed significant alterations over time in acute exercise and exercise training context,but only a few investigations showed significant differences compared to control conditions.Secretory and plasma immunoglobulin A levels were most consistently increased in response to exercise training.Conclusion:B cell-related outcomes are altered by acute exercise and exercise training,but evidence-based conclusions cannot be drawn with high confidence due to the large heterogeneity in populations and exercise modalities.Well-designed trials with large sample sizes are needed to clarify how exercise shapes B cell-related immunity.

关键词： Antibody B-lymphocyte Exercise Humoral immunity Immune system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mechanically Joined Extrusion Profiles for Battery Trays

引用

Automotive Innovation 2024年第1期7卷 182-193页

作者： Florian Kneuper Stefan Neumann AndréSchulze Mortaza Otroshi A.Erman Tekkaya Gerson Meschut Institute of Forming Technology and Lightweight Components(IUL) TU Dortmund University44227 DortmundGermany Laboratory for Material and Joining Technology(LWF) Paderborn UniversityPaderbornGermany

In the context of electromobility,ensuring the leak tightness of assemblies is of paramount importance,particularly in bat-tery housings.Current battery housings,often featuring base assemblies crafted from extruded aluminum profiles,address the challenge of leak tightness at joints through methods like friction stir welding,a process known for its time and cost intensiveness.The aim of this study is to develop and implement a new type of extruded profile concept to produce tight base assemblies for battery housings by a longitudinal mechanical single stroke joining process.The geometry,the process and the properties of the aluminum profiles are investigated to get a joint that meets the tightness requirements and achieve high load-bearing capacities in agreement with the high homologation requirements set to vehicles with high-voltage systems.The joint is formed by means of a single stage press stroke,which eliminates the need for complex tool designs that are neces-sary for continuous joining(roll joining).Flat steel contact surfaces are used as joining tools.To evaluate the joint quality,force curves from the joining process are analyzed and the resulting joint geometries are assessed using micrographs.The resulting leak tightness of the linear joints is measured by a helium sniffer leak detector and the load-bearing capacities are investigated by shear lap and bending tests and fatigue strength test.The study also explores whether a difference in strength between the two joining partners has a positive effect on the joint properties.

关键词： Joining by plastic deformation Aluminum Leak Tightness

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nonlinear Rydberg exciton-polaritons in Cu2O microcavities

引用

Light(Science & Applications) 2024年第4期13卷 619-627页

作者： Maxim Makhonin Anthonin Delphan Kok Wee Song Paul Walker Tommi Isoniemi Peter Claronino Konstantinos Orfanakis Sai Kiran Rajendran Hamid Ohadi Julian Heckötter Marc Assmann Manfred Bayer Alexander Tartakovskii Maurice Skolnick Oleksandr Kyriienko Dmitry Krizhanovskii Department of Physics and Astronomy University of SheffieldSheffield S37RHUK. Department of Physics and Astronomy University of ExeterStocker RoadExeter EX44PYUK. SUPA School of Physics and AstronomyUniversity of St AndrewsSt Andrews KY169SSUK. Fakultät Physik TU DortmundAugust-Schmidt-Straße 444227 DortmundGermany

Rydberg excitons(analogues of Rydberg atoms in condensed matter systems)are highly excited bound electron-hole states with large Bohr radii.The interaction between them as well as exciton coupling to light may lead to strong optical nonlinearity,with applications in sensing and quantum information processing.Here,we achieve strong effective photon–photon interactions(Kerr-like optical nonlinearity)via the Rydberg blockade phenomenon and the hybridisation of excitons and photons forming polaritons in a Cu2O-filled microresonator.Under pulsed resonant excitation polariton resonance frequencies are renormalised due to the reduction of the photon-exciton coupling with increasing exciton density.Theoretical analysis shows that the Rydberg blockade plays a major role in the experimentally observed scaling of the polariton nonlinearity coefficient as∝n4.4±1.8 for principal quantum numbers up to n=7.Such high principal quantum numbers studied in a polariton system for the first time are essential for realisation of high Rydberg optical nonlinearities,which paves the way towards quantum optical applications and fundamental studies of strongly correlated photonic(polaritonic)states in a solid state system.

关键词： density. Rydberg polar

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparation of microparticles and nanoparticles using membrane-assisted dispersion,micromixing,and evaporation processes

引用

Particuology 2024年第1期84卷 30-44页

作者： Goran T.Vladisavljevic Chemical Engineering Department Loughborough UniversityLoughboroughLeicestershire LE113TUUnited Kingdom

Synthetic microporous membranes are increasingly used for energy-efficient and controlled production of micro-and nanoparticles and micro-and nanoemulsions with tuneable morphology and physico-chemical properties through various micromixing,emulsification,and evaporation processes.In emul-sification processes,the membrane pores are used for dispersed phase injection and size-controlled generation of droplets and droplet-templated particles.In micromixing processes,membrane is utilised as a micromixer for mixing two miscible liquids,usually solvent and antisolvent-rich solutions,which leads to the creation of supersaturation and subsequent nanoprecipitation or crystallisation.In mem-brane evaporation processes,membrane is used to prevent phase dispersion while allowing efficient molecular diffusion of solvent and/or antisolvent vapour through gas-filled pores.Membrane dispersion processes can be operated continuously by decoupling shear stress on the membrane surface from cross flow using tube insets,flow pulsations,swirling flow,membrane oscillations or membrane rotations.Droplet generation and solidification can be performed continuously in a single pass by connecting membrane module with a downstream reactor.Membrane dispersion processes can be used for pro-duction of nanoparticles such as nanovesicles(liposomes,micelles,ethosomes,and niosomes),nanogels,polymeric,lipid and metallic nanoparticles,and nanocrystals.The main advantages of membrane-assisted particle generation are in low energy consumption,controlled geometry and hydrodynamic conditions at the microscale level,flexible throughput due to modular and scalable design of membrane devices,and a wide choice of available microporous membranes with various wall porosities,wetta-bilities,pore sizes,and pore morphologies to suit different applications.

关键词： Nanoparticles Microparticles Nanoemulsions Microemulsions Microporous membrane Crystallisation Flash nanoprecipitation Emulsification Zero liquid discharge

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Goal-Oriented Control Systems(GOCS):From HOW to WHAT

引用

IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 816-819页

作者： Wen-Hua Chen the Department of Aeronautical and Automotive Engineering Loughborough UniversityLeicestershireLE113TUU.K.

Brief:New control theory is required to underpin safe design and deployment of future highly automated systems to deal with uncertain environments and complicated tasks,enabled by AI and other advanced technologies.Goal-Oriented Control Systems offer potential to transform the control system design from currently instructing a control system how to perform a task to specifying what is to be achieved.

关键词： automated instru system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficient slope reliability analysis under soil spatial variability using maximum entropy distribution with fractional moments

引用

Journal of Rock Mechanics and Geotechnical Engineering 2024年第4期16卷 1140-1152页

作者： Chengxin Feng Marcos A.Valdebenito Marcin Chwała Kang Liao Matteo Broggi Michael Beer Institute for Risk and Reliability Leibniz University HannoverCallinstr.34Hannover30167Germany Chair for Reliability Engineering TU Dortmund UniversityLeonhard-Euler-Str.5Dortmund44227Germany Faculty of Civil Engineering Wrocƚaw University of Science and TechnologyWrocƚawPoland Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu610031China university of Liverpool Institute for Risk and UncertaintyPeach StreetLiverpoolL69 7ZFUnited Kingdom International Joint Research Center for Resilient Infrastructure & International Joint Research Center for Engineering Reliability and Stochastic Mechanics Tongji UniversityShanghaiChina

Spatial variability of soil properties imposes a challenge for practical analysis and design in geotechnical engineering.The latter is particularly true for slope stability assessment,where the effects of uncertainty are synthesized in the so-called probability of failure.This probability quantifies the reliability of a slope and its numerical calculation is usually quite involved from a numerical viewpoint.In view of this issue,this paper proposes an approach for failure probability assessment based on Latinized partially stratified sampling and maximum entropy distribution with fractional moments.The spatial variability of geotechnical properties is represented by means of random fields and the Karhunen-Loève expansion.Then,failure probabilities are estimated employing maximum entropy distribution with fractional moments.The application of the proposed approach is examined with two examples:a case study of an undrained slope and a case study of a slope with cross-correlated random fields of strength parameters under a drained slope.The results show that the proposed approach has excellent accuracy and high efficiency,and it can be applied straightforwardly to similar geotechnical engineering problems.

关键词： Slope Random field Reliability analysis Maximum entropy distribution Latinized partial stratified sampling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrating Levels of Hierarchical Organization in Porous Organic Molecular Materials

引用

Nano-Micro Letters 2024年第5期16卷 134-153页

作者： Jesus Ferrando‑Soria Antonio Fernandez Instituto de Ciencia Molecular(ICMol) Universidad de Valencia46980 ValenciaSpain School of Science Loughborough UniversityLoughborough LE113TUUK

Porous organic molecular materials(POMMs)are an emergent class of molecular-based materials characterized by the formation of extended porous frameworks,mainly held by non-covalent interactions.POMMs represent a variety of chemical families,such as hydrogen-bonded organic frameworks,porous organic salts,porous organic cages,C-H···πmicroporous crystals,supramolecular organic frameworks,π-organic frameworks,halogen-bonded organic framework,and intrinsically porous molecular materials.In some porous materials such as zeolites and metal organic frameworks,the integration of multiscale has been adopted to build materials with multifunctionality and optimized properties.Therefore,considering the significant role of hierarchy in porous materials and the growing importance of POMMs in the realm of synthetic porous materials,we consider it appropriate to dedicate for the first time a critical review covering both topics.Herein,we will provide a summary of literature examples showcasing hierarchical POMMs,with a focus on their main synthetic approaches,applications,and the advantages brought forth by introducing hierarchy.

关键词： Porous organic molecular materials Hierarchy Hydrogen-bonded organic frameworks Porous cages Fullerene

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Distributed Dynamic Load in Structural Dynamics by the Impulse-Based Force Estimation Algorithm

引用

Computer Modeling in Engineering & Sciences 2024年第6期139卷 2865-2891页

作者： Yuantian Qin Yucheng Zhang Vadim V.Silberschmidt College of Astronautics Nanjing University of Aeronautics and AstronauticsNanjing210016China Wolfson School of Mechanical Electrical and Manufacturing EngineeringLoughborough UniversityLoughboroughLE113TUUK

This paper proposes a novel approach for identifying distributed dynamic loads in the time domain.Using polynomial andmodal analysis,the load is transformed intomodal space for coefficient identification.This allows the distributed dynamic load with a two-dimensional form in terms of time and space to be simultaneously identified in the form of modal force,thereby achieving dimensionality reduction.The Impulse-based Force Estimation Algorithm is proposed to identify dynamic loads in the time domain.Firstly,the algorithm establishes a recursion scheme based on convolution integral,enabling it to identify loads with a long history and rapidly changing forms over time.Secondly,the algorithm introduces moving mean and polynomial fitting to detrend,enhancing its applicability in load estimation.The aforementioned methodology successfully accomplishes the reconstruction of distributed,instead of centralized,dynamic loads on the continuum in the time domain by utilizing acceleration response.To validate the effectiveness of the method,computational and experimental verification were conducted.

关键词： Distributed force estimation time domain deconvolution recursion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interactive mechanism and friction modelling of transient tribological phenomena in metal forming processes: A review

引用

Friction 2024年第3期12卷 375-395页

作者： Xiao YANG Heli LIU Lemeng ZHANG Yiran HU Denis J.POLITIS Mohammad M.GHARBI Liliang WANG Department of Mechanical Engineering Imperial College LondonLondon SW72AZUK Department of Mechanical and Manufacturing Engineering University of CyprusNicosia 1678Cyprus Quaker Houghton Deutschland GmbH Dortmund 44319Germany

The accurate representation of tribological boundary conditions at the tool–workpiece interface is crucial for analysis and optimization of formability,material flow,and surface quality of components during metal forming processes.It has been found that these tribological conditions vary spatially and historically with process parameters and contact conditions.These time-dependent tribological behaviours are also known as transient tribological phenomena,which are widely observed during forming processes and many other manufacturing application scenarios.However,constant friction values are usually assigned to represent complex and dynamic interfacial conditions,which would introduce deviations in the relevant predictions.In this paper,transient tribological phenomena and the contemporary understanding of the interaction between friction and wear are reviewed,and it has been found that these phenomena are induced by the transitions of friction mechanisms and highly dependent on complex loading conditions at the interface.Friction modelling techniques for transient behaviours for metal forming applications are also reviewed.To accurately describe the evolutionary friction values and corresponding wear during forming,the advanced interactive friction modelling has been established for different application scenarios,including lubricated condition,dry sliding condition(metal-on-metal contact),and coated system.

关键词： transient tribological phenomena interactive friction mechanism modelling techniques metal forming

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental and computational analysis of the coolant distribution considering the viscosity of the cutting fluid during machining with helical deep hole drills

引用

Advances in Manufacturing 2022年第2期10卷 235-249页

作者： Ekrem Oezkaya Sebastian Michel Dirk Biermann Institute of Machining Technology Dortmund University of Technology(TU Dortmund)Dortmund 44227Germany

An experimental analysis regarding the distribution of the cutting fluid is very difficult due to the inaccessibility of the contact zone within the bore hole.Therefore,suitable simulation models are necessary to evaluate new tool designs and optimize drilling processes.In this paper the coolant distribution during helical deep hole drilling is analyzed with high-speed microscopy.Micro particles are added to the cutting fluid circuit bya developed high-pressure mixing vessel.After the evaluation of suitable particle size,particle concentration and coolant pressure,a computational fluid dynamics(CFD)simulation is validated with the experimental results.The comparison shows a very good model quality with a marginal difference for the flow velocity of 1.57%between simulation and experiment.The simulation considers the kinematic viscosity of the fluid.The results show that the fluid velocity in the chip flutes is low compared to the fluid velocity at the exit of the coolant channels of the tool and drops even further between theguidechamfers.Theflow velocity and the flow pressure directly at the cutting edge decrease to such an extent that the fluid cannot generate a sufficient cooling or lubrication.With the CFD simulation a deeper understanding of the behavior and interactions of the cutting fluid is achieved.Based on these results further research activities to improve the coolant supply can be carried out with great potential to evaluate new tool geometries and optimize the machining process.

关键词： Computational fluid dynamics(CFD)analysis:Viscosity-Tracermicro particles Fluidbehavior Helical deep hole drilling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：