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IEEE/CAA Journal of Automatica Sinica 2024年第10期11卷 2059-2067页

作者： Zeqiang Li Yujuan Wang Yongduan Song international Joint Laboratory on Safety and Control of Autonomous Unmanned systems School of AutomationChongqing UniversityChongqing 400044China IEEE

It is interesting yet nontrivial to achieve given control precision within user-assignable time for uncertain nonlinear *** underlying problem becomes even more challenging if the transient behavior also needs to be accommodated and only system output is available for *** key design innovations are proposed to circumvent the aforementioned technical difficulties,including the employment of state estimation filters with event-triggered mechanism,the construction of a novel performance scaling function and an error *** contrast to most existing performance based works where the stability is contingent on initial conditions and the maximum allowable steady-state tracking precision can only be guaranteed at some unknown(theoretically infinite)time,in this work the output of the system is ensured to synchronize with the desired trajectory with arbitrarily pre-assignable convergence rate and arbitrarily pre-specified precision within prescribed time,using output only with lower cost of sensing and *** addition,all the closed-loop signals are ensured to be globally uniformly bounded under the proposed control *** merits of the designed control scheme are confirmed by numerical simulation on a ship model.

关键词： Adaptive control nonlinear systems output feedback prescribed performance

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Advanced nanotherapeutics inspired by the abnormal microenvironment of leukemia

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Nano Research 2024年第9期17卷 8285-8300页

作者： Hao Zhang Tian Liu Mengyu Liu Shuo Wang Yuetong Huang Yifan Ma Bingjun Sun Zhonggui He Jin Sun Department of Pharmaceutics Wuya College of InnovationShenyang Pharmaceutical UniversityShenyang 110016China Joint international Research Laboratory of Intelligent Drug Delivery systems Ministry of EducationShenyang 110016China

During the development of leukemia,the overgrowth of leukemia cells in the bone marrow transforms the normal hematopoietic microenvironment into the leukemia microenvironment which favors its growth and inhibits normal hematopoietic stem *** leukemia microenvironment exhibits abnormalities in redox substances,metabolism,immune response,mesenchymal cells,extracellular matrix,stromal cells,hypoxia,and *** factors collectively provide a shelter for the malignant proliferation of leukemia ***,as the understanding of the leukemia microenvironment deepens,targeting or remodeling the abnormal leukemia microenvironment is becoming an effective strategy for leukemia *** technology can effectively change pharmacokinetic profiles,thus demonstrating many advantages in modulating the leukemia microenvironment and improving therapeutic *** this review,we outline the characteristics of abnormal leukemia bone marrow microenvironment,focusing on the abnormal changes in the redox,metabolic and immune *** also summarize emerging nanotechnology strategies in remodeling or targeting the aforementioned abnormal *** addition,the unique advantages and bright prospects of nanotechnology in remodeling and targeting the leukemia microenvironment are discussed.

关键词： nanotherapeutics immunity metabolism redox leukemia microenvironment

Energy-Function Based Pilot Protection Scheme for Hybrid UHVDC Transmission Applying Improved Hausdorff Distance

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CSEE Journal of Power and Energy systems 2024年第3期10卷 891-902页

作者： Zijiang Wang Youping Fan Ben Shang Yinbiao Shu School of Electrical Engineering and Automation Wuhan UniversityWuhan 430072China Institute of Next Generation Power systems&international Standards Wuhan UniversityWuhan 430072China CSEE IEEE

A hybrid UHVDC transmission system applying LCC as the rectifier and MMC as the inverter combines the advantages of both converter types,which makes this protection scheme more complicated.A new pilot protection scheme for a three-terminal hybrid DC transmission system applying energy functions is *** energy function for LCC is applied to MMC to derive the energy level of the hybrid ***,an improved Hausdorff distance(IHD)algorithm is proposed to detect the difference in energy levels between the normal and fault *** abrupt change in energy level is characterized by IHD change *** points at which the IHD change rate exceeds the threshold at converter stations are applied to determine the fault line and to estimate the fault *** proposed protection scheme is then verified by a simulation model of the Wudongde±800 kV three-terminal hybrid UHVDC transmission *** appropriate sampling frequency is selected for a real-time calculation,and the threshold is selected considering the effect of *** show the proposed scheme can identify and trip fault lines quickly and effectively,even for a 600Ωgrounding *** waveshape similarity algorithms are compared and *** with existing protection schemes,the proposed scheme transmits less data to improve communication speed and reliability.

关键词： Energy function Hausdorff distance pilot protection UHVDC transmission

Flexible pressure sensors with ultrahigh stress tolerance enabled by periodic microslits

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Microsystems & Nanoengineering 2024年第1期10卷 301-311页

作者： Song Wang Chenying Wang Yifan Zhao Yujing Zhang Yaxin Zhang Xiangyue Xu Qijing Lin Kai Yao Yuheng Wang Feng Han Yu Sun Zhuangde Jiang State Key Laboratory for Manufacturing systems Engineering International Joint Laboratory for Micro/Nano Manufacturing and Measurement TechnologiesSchool of Mechanical EngineeringXi’an Jiaotong UniversityXi’anChina State Key Laboratory for Manufacturing systems Engineering International Joint Laboratory for Micro/Nano Manufacturing and Measurement TechnologiesSchool of Instrument Science and TechnologyXi’an Jiaotong UniversityXi’anChina The Faculty of Electrical Engineering and Computer Science Ningbo UniversityNingboChina Department of Mechanical and Industrial Engineering University of TorontoTorontoCanada

Stress tolerance plays a vital role in ensuring the effectiveness of piezoresistive sensing films used in flexible pressure ***,existing methods for enhancing stress tolerance employ dome-shaped,wrinkle-shaped,and pyramidal-shaped microstructures in intricate molding and demolding processes,which introduce significant fabrication challenges and limit the sensing *** address these shortcomings,this paper presents periodic microslits in a sensing film made of multiwalled carbon nanotubes and polydimethylsiloxane to realize ultrahigh stress tolerance with a theoretical maximum of 2.477 MPa and a sensitivity of 18.092 kPa−*** periodic microslits permit extensive deformation under high pressure(e.g.,400 kPa)to widen the detection ***,the periodic microslits also enhance the sensitivity based on simultaneously exhibiting multiple synapses within the sensing interface and between the periodic sensing *** proposed solution is verified by experiments using sensors based on the microslit strategy for wind direction detection,robot movement sensing,and human health *** these experiments,vehicle load detection is achieved for ultrahigh pressure sensing under an ultrahigh pressure of over 400 kPa and a ratio of the contact area to the total area of 32.74%.The results indicate that the proposed microslit strategy can achieve ultrahigh stress tolerance while simplifying the fabrication complexity of preparing microstructure sensing films.

关键词： robot shaped stress

systems science in the new era: intelligent systems and big data

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Science China(Information Sciences) 2024年第3期67卷 308-310页

作者： Wenwu YU Duxin CHEN Hongzhe LIU He WANG Jinde CAO Zengru DI Xiaojun DUAN Bin JIA Xiaodong DING Yiguang HONG School of Mathematics Southeast University Purple Mountain Laboratories international Academic Center of Complex systems Beijing Normal University College of Science National University of Defense Technology School of systems Science Beijing Jiaotong University Business School University of Shanghai for Science and Technology Department of Control Science and Engineering Tongji University

This study introduces the emergence, research challenges,and future development of intelligent systems and big data(ISBD) and discusses the significance of ISBD to systems science. To this end, an overview of systems science is first presented, followed by the conclusion that the development of artificial intelligence(AI) has promoted the derivation and development of intelligent systems(ISs).

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Contact engineering for temperature stability improvement of Bi-contacted MoS2 field effect transistors

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Science China(Information Sciences) 2024年第06期67卷 172-179页

作者： Zizheng LIU Qing ZHANG Xiaohe HUANG Chunsen LIU Peng ZHOU State Key Laboratory of Integrated Chip and systems School of MicroelectronicsZhangjiang Fudan International Innovation CenterFudan University Frontier Institute of Chip and System Shanghai Key Lab for Future Computing Hardware and SystemFudan University Shaoxin Laboratory

Semimetallic bismuth（Bi） is one of the most effective strategies for reducing the contact resistance of two-dimensional transition metal dichalcogenide field effect transistors（FETs）. However, the low melting point of Bi contact（271.5℃） limits its reliable applications. In this study, we demonstrated that the temperature stability of Bi-contacted electrodes could be improved by inserting a high-melting point semimetallic antimony（Sb） between the Bi contacting layer and the gold（Au） capping layer. The proposed Bi/Sb/Au contact electrodes tended to form a metal mixture with a continuous surface during the heating process（Voids appeared on the surface of the Bi/Au contact electrodes after heating at 120℃）. Because of the improved contacting layer formed by the semimetal Bi/Sb alloy, the fabricated Bi/Sb/Au-contacted molybdenum sulfide（MoS2） FETs with different gate lengths demonstrated higher on-state current stability after heating treatment than the Bi/Au contact. Because of the Bi/Sb/Au contact and poly（methyl methacrylate） package, the MoS2FETs demonstrated time stability of at least two months from the almost unchanged transfer characteristics. The electrical stability indicates that the insertion of semimetallic Sb is a promising technology for reliable Bi-based contact.

关键词： temperature stability semimetallic bismuth contact semimetallic antimony contact MoS$_{2}$ FETs time stability

Simultaneously quantifying hundreds of acylcarnitines in multiple biological matrices within ten minutes using ultrahigh-performance liquid-chromatography and tandem mass spectrometry

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Journal of Pharmaceutical Analysis 2024年第1期14卷 140-148页

作者： Jingxian Zhang Qinsheng Chen Lianglong Zhang Biru Shi Men Yu Qingxia Huang Huiru Tang State Key Laboratory of Genetic Engineering School of Life SciencesHuman Phenome InstituteZhangjiang Fudan International Innovation CenterMetabonomics and Systems Biology Laboratory at Shanghai International Centre for Molecular PhenomicsZhongshan HospitalFudan UniversityShanghai200032China Wuhan Laboratory for Shanghai Metabolome Institute(SMI)Ltd. Wuhan430000China

Acylcarnitines are metabolic intermediates of fatty acids and branched-chain amino acids having vital biofunctions and pathophysiological significances. Here, we developed a high-throughput method for quantifying hundreds of acylcarnitines in one run using ultrahigh performance liquid chromatography and tandem mass spectrometry (UPLC-MS/MS). This enabled simultaneous quantification of 1136 acylcarnitines (C0–C26) within 10-min with good sensitivity (limit of detection 0.992), accuracy (relative error 0.998) for predicting retention time (tR) of acylcarnitines with no standards and built a database of their multiple reaction monitoring parameters (tR, ion-pairs, and collision energy). Furthermore, we quantified 514 acylcarnitines in human plasma and urine, mouse kidney, liver, heart, lung, and muscle. This provides a rapid method for quantifying acylcarnitines in multiple biological matrices.

关键词： Acylcarnitine UPLC-MS/MS Quantitative structure-retention relationship Molecular phenotype

Positive definiteness of real quadratic forms resulting from the variable-step L1-type approximations of convolution operators

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Science China Mathematics 2024年第2期67卷 237-252页

作者： Hong-Lin Liao Tao Tang Tao Zhou School of Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 211106China Division of Science and Technology BNU-HKBU United International CollegeZhuhai 519087China SUSTech international Center for Mathematics Shenzhen 518055China NCMIS&LSEC Institute of Computational Mathematics and Scientific/Engineering ComputingAcademy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China

The positive definiteness of real quadratic forms with convolution structures plays an important rolein stability analysis for time-stepping schemes for nonlocal operators. In this work, we present a novel analysistool to handle discrete convolution kernels resulting from variable-step approximations for convolution *** precisely, for a class of discrete convolution kernels relevant to variable-step L1-type time discretizations, weshow that the associated quadratic form is positive definite under some easy-to-check algebraic conditions. Ourproof is based on an elementary constructing strategy by using the properties of discrete orthogonal convolutionkernels and discrete complementary convolution kernels. To our knowledge, this is the first general result onsimple algebraic conditions for the positive definiteness of variable-step discrete convolution kernels. Using theunified theory, we obtain the stability for some simple nonuniform time-stepping schemes straightforwardly.

关键词： discrete convolution kernels positive definiteness variable time-stepping orthogonal convolution kernels complementary convolution kernels

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Solar manipulations of perpendicular magnetic anisotropy for flexible spintronics

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Frontiers of physics 2024年第4期19卷 73-79页

作者： Zhexi He Yifan Zhao Yujing Du Meng Zhao Yuxuan Jiang Ming Liu Ziyao Zhou State Key Laboratory for Manufacturing systems Engineering Electronic Materials Research LaboratoryKey Laboratory of the Ministry of Education&International Center for Dielectric ResearchSchool of Electronic Science and EngineeringThe International Joint Laboratory for Micro/Nano Manufacturing and Measurement TechnologyXi’an Jiaotong UniversityXi’an 710049China School of Materials Science&Engineering Changzhou UniversityChangzhou 213164China

Flexible electronics/spintronics attracts researchers’attention for their application potential abroad in wearable devices,healthcare,and other *** devices’performance(speed,energy consumption)is highly dependent on manipulating information bits(spin-orientation in flexible spintronics).In this work,we established an organic photovoltaic(OPV)/ZnO/Pt/Co/Pt heterostructure on flexible PET substrates with perpendicular magnetic anisotropy(PMA).Under sunlight illumination,the photoelectrons generated from the OPV layer transfer into the PMA heterostructure,then they reduce the PMA strength by enhancing the interfacial Rashba field *** coercive field(Hc)reduces from 800 Oe to 500 Oe at its maximum,and the magnetization can be switched up and down *** stability of sunlight control of magnetization reversal under various bending conditions is also tested for flexible spintronic ***,the voltage output of sunlight-driven PMA is achieved in our prototype device,exhibiting an excellent angular dependence and opening a door towards solar-driven flexible spintronics with much lower energy consumption.

关键词： interfacial magnetoelectric coupling perpendicular magnetic anisotropy deterministic magnetization reversal photovoltaic control of magnetism