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Atomic-resolution characterization on the structure of strontium doped barium titanate nanoparticles

Nano Research 2021年第12期14卷 4802-4807页

作者： Haoyu Jiang Jizhen Qi Dongchang Wu Wei Lu Jiahui Qian Haifeng Qu Yixiao Zhang Pei Liu Xi Liu Liwei Chen In-situ Center for Physical Sciences School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai200240China i-Lab CAS Center for Excellence in Nanoscience Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinese Academy of SciencesSuzhou215123China suzhou bao shun mei technology co. Ltd.Room 305Building 1199 Jinji Lake AvenueSuzhou Industrial ParkSuzhou215123China DTU Nanolab Technical University of DenmarkFysikvejBuilding 3072800LyngbyDenmark Shanghai Nanoport Thermo Fisher Scientific Building A2517 Jinke RoadPudong DistrictShanghai201203China

Ferroelectric barium titanate nanoparticles(BTO NPs)may play critical roles in miniaturized passive electronic devices such as multi-layered ceramic *** increasing experimental and theoretical understandings on the structure of BTO and doped BTO have been developed over the past decade,the majority of the investigation was carried out in thin-film materials;therefore,the doping effect on nanoparticles remains ***,doping-induced local co.position and structure fluctuation across single nanoparticles have yet to be *** this work,we use electron microsco.y-based techniques including high-angle annular dark-field scanning transmission electron microsco.y(HAADF-STEM),integrated differential phase co.trast(iDPC)-STEM,and energy dispersive X-ray spectrosco.y(EDX)mapping to reveal atomically resolved chemical and crystal structure of BTO and strontium doped BTO *** X-ray diffraction(PXRD)results indicate that the increasing strontium doping causes a structural transition from tetragonal to cubic phase,but the microsco.ic data validate substantial co.positional and microstructural inhomogeneities in strontium doped BTO *** work provides new insights into the structure of doped BTO NPs and will facilitate the materials design for next-generation high-density nano-dielectric devices.

关键词： barium titanate nanoparticles doping effect structural transition high-angle annular dark-field scanning transmission electron microsco.y integrated differential phase co.trast

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Silico. carbide and graphene based UV-IR dual-co.or detector

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Optoelectronics Letters 2019年第3期15卷 170-173页

作者：曾春红林文魁孙玉华崔奇张璇李绍娟张宝顺孔梅 Changchun University of Science and technology Changchun130022China suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of SciencesSuzhou215123China Funsom&co.laborative Innovation Center of suzhou Nano Science and technology Suzhou UniversitySuzhou215123China

An ultraviolet-infrared dual-co.or detector is proposed and realized based on the vertical integration of single-layer graphene and a 4 H-SiC layer by semico.ductor micro-fabrication technology. The spectral response characteristics of the detector are analyzed. The ultraviolet response range is 208—356 nm with a responsivity larger than 0.4 mA/W and the infrared response range is 1.016—1.17 μm with a responsivity larger than 0.4 mA/W at room temperature and 5 V bias voltage. The peak responsivity of the graphene in the ultraviolet-C band at 232 nm is 0.73 mA/W and in the near infrared band at 1.148 μm is 0.64 mA/W. The peak responsivity of SiC layer in the ultraviolet-B band at 312 nm is 2.27 mA/W. Besides, the responsivity increases with the bias voltage.

关键词： Silico. carbide and graphene based UV-IR dual-co.or detector SiC UV IR

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A High Power InGaN-Based Blue-Violet Laser Diode Array with a Broad-Area Stripe

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Chinese Physics Letters 2013年第10期30卷 104-107页

作者：陈平赵德刚冯美鑫江德生刘宗顺张立群李德尧刘建平王辉朱建军张书明张宝顺杨辉 State Key Laboratory on Integrated Optoelectronics Institute of SemiconductorsChinese Academy of SciencesBeijing 100083 Key Laboratory of Nanodevices and Applications of CAS Suzhou Institute of Nano-tech and Nano-bionicsChinese Academy of SciencesSuzhou 215123

An array of high power InGaN/GaN multi-quantum-well laser diodes with a broad waveguide is *** laser diode structure is grown on a GaN substrate by metal-organic chemical vapor *** laser diode array co.sists of five emitter stripes which share co.mon electrodes on one laser *** electrical and optical characteristics of the laser diode array are investigated under the pulse current injection with 10 kHz frequency and 100 ns pulse *** laser diode array emits at the wavelength of 409 nm,which is located in the blue-violet region,and the threshold current is 2.9 *** maximum output light peak power is measured to be 7.5 W at the wavelength of 411.8 nm under the current of 25 A.

关键词： InGaN/GaN waveguide diode

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Efficacy and Safety of Teriflunomide in Chinese Patients with Relapsing Forms of Multiple Sclerosis: A Subgroup Analysis of the Phase 3 TOWER Study

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Chinese Medical Journal 2018年第23期131卷 2776-2784页

作者： Wei Qiu De-Hui Huang Shi-Fang Hou mei-Ni Zhang Tao Jin Hui-Qing Dong Hua Peng Chao-Dong Zhang Gang Zhao Yi-Ning Huang Dong Zhou Wei-Ping Wu bao-Jun Wang Ji-mei Li Xing-Hu Zhang Yan Cheng Hai-Feng Li Ling Li Chuan-Zhen Lu Xu Zhang Bi-Tao Bu Wan-Li Dong Dong-Sheng Fan Xue-Qiang Hu Xian-Hao Xu Department of Neurology The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouGuangdong 510000China Department of Neurology Peking University First HospitalBeijing 100034China Department of Neurology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Neurology Baotou Central HospitalBaotouInner Mongolia 014040China Department of Neurology Beijing Friendship HospitalCapital Medical UniversityBeijing 100000China Department of Neurology Beijing Tian Tan HospitalCapital Medical UniversityBeijing 100050China Department of Neurology Tianjin Medical University General HospitalTianjin 300052China Department of Neurology The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266003China Department of Neurology Hebei General HospitalShijiazhuangHebei 050051China Department of Neurology Hua Shah Hospital of the Shanghai Fudan University Medical CollegeShanghai 200040China Department of Neurology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang 325000China Department of Neurology Chinese People's Liberation Army General HospitalBeijing 100853China Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China Department of Neurology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215000China Department of Neurology Beijing HospitalNational Center of GerontologyBeijing 100083China Qilu Hospital of Shandong University JinanShandong 250012China Department of Neurology Beijing HospitalBeijing 100730China Department of Neurology The First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Neurology The First Hospital of Jilin UniversityChangchunJilin 130012China Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing 100053China Department of Neurology Shanghai Chang Zheng HospitalShanghai 200003China Department of Neurology The First Hospital of China Medical UniversityShenyang

Background:Disease-modifying therapy is the standard treatment for patients with multiple sclerosis (MS)in *** primary objective of the current analysis was to assess the efficacy and safety of two teriflunomide doses (7mg and 14mg)in the subgroup of Chinese patients with relapsing MS included in the TOWER study. Methods:TOWER was a multicenter,multinational,randomized, double-blind,parallel-group (three groups),placebo-co.trolled *** subgroup analysis includes 148 Chinese patients randomized to receive either teriflunomide 7mg (n =51), teriflunomide 14mg (n=43),or placebo (n=54). Results:Of the 148patients in the intent-to-treat population, adjusted annualized-relapse rates were 0.63(95% co.fidence interval [CI]:0.44,0.92)in the placebo group,0.48(95%CI:0.33, 0.70)in the teriflunomide 7mg group,and 0.18(95%CI:0.09,0.36)in the terifltmomide 14mg group;this co.responded to a significant relative risk reduction in the teriflunomide 14mg group versus placebo (-71.2%,P =0.0012).Terifiunomide 14mg also tended to reduce 12-week co.firmed disability worsening by 68.1% co.pared with placebo (hazard ratio:0.319,P =0.1194).There were no differences across all treatment groups in the proportion of patients with treatment-emergent adverse events (TEAEs;72.2% in the placebo group,74.5%in the teriflunomide 7mg group,and 69.8% in the teriflunomide 14mg group);co.responding proportions for serious adverse events were 11.1%,3.9%,and 11.6%,*** most frequently reported TEAEs with teriflunomide versus placebo were neutropenia,increased alanine aminotransferase,and hair thinning. co.clusions:Teriflunomide was as effective and safe in the Chinese subpopulation as it was in the overall population of patients in the TOWER *** has the potential to meet unmet medical needs for MS patients in China.

关键词： Chinese Patients Efficacy Phase 3 Relapsing Multiple Sclerosis Safety Teriflunomide TOWER

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