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3D printing of silk fibroin-based hybrid scaffold treated with platelet rich plasma for bone tissue engineering

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Bioactive Materials 2019年第1期4卷 256-260页

作者： Liang Wei Shaohua Wu Mitchell Kuss Xiping Jiang Runjun Sun Reid Patrick Xiaohong Qin Duan Bin School of Textile Science and Engineering Xi'an Polytechnic UniversityXi'an710048PR China Mary&Dick Holland Regenerative Medicine Program Division of CardiologyDepartment of Internal MedicineUniversity of Nebraska Medical CenterOmahaNE68198USA Key Laboratory of Textile Science&technology Ministry of EducationCollege of TextilesDonghua UniversityShanghai201620PR China College of Textiles&Clothing Qingdao UniversityQingdao266071PR China Department of Pathology&Microbiology College of MedicineUniversity of Nebraska Medical CenterOmahaNE68198USA Department of Surgery College of MedicineUniversity of Nebraska Medical CenterOmahaNE68198USA Department of Mechanical and Materials Engineering University of Nebraska-LincolnLincolnNE68516USA

3D printing/bioprinting are promising techniques to fabricate scaffolds with well controlled and patient-specific structures and architectures for bone tissue *** this study,we developed a composite bioink consisting of silk fibroin(SF),gelatin(GEL),hyaluronic acid(HA),and tricalcium phosphate(TCP)and 3D bioprinted the silk fibroin-based hybrid *** 3D bioprinted scaffolds with dual crosslinking were further treated with human platelet-rich plasma(PRP)to generate PRP coated ***/Dead and MTT assays demonstrated that PRP treatment could obviously promote the cell growth and proliferation of human adipose derived mesenchymal stem cells(HADMSC).In addition,the treatment of PRP did not significantly affect alkaline phosphatase(ALP)activity and expression,but significantly upregulated the gene expression levels of late osteogenic *** study demonstrated that the 3D printing of silk fibroin-based hybrid scaffolds,in combination with PRP post-treatment,might be a more efficient strategy to promote osteogenic differentiation of adult stem cells and has significant potential to be used for bone tissue engineering.

关键词： 3D bioprinting Hybrid scaffold Coating Growth factor cocktail Tissue engineering

National Alveolar Echinococcosis Distribution--China, 2012−2016

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China CDC weekly 2020年第1期2卷 1-7页

作者： Canjun Zheng Chuizhao Xue Shuai Han Zhongjie Li Hu Wang Liying Wang Ying Wang Qian Wang Yu Feng Yanyan Hou Xiao Ma Junying Ma Xiumin Han Gongsang Quzhen Xiaofeng Jiang Weidong Guo Xianglin Wu Yaming Yang Lei Cao Fanka Li Weiqi Chen Xinliu Yan Shicheng Yu Meihua Fu Qing Yu Ning Xiao Jiangping Cao Jun Yan Weiping Wu Xiao-nong Zhou Division of Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionChinese Center for Tropical Diseases ResearchWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesMinistry of Science and TechnologyKey Laboratory of Parasite and Vector BiologyMinistry of HealthShanghaiChina Health Commission of Qinghai Province XiningQinghaiChina Sichuan Provincial Center for Disease Control and Prevention ChengduSichuanChina Gansu Provincial Center for Disease Control and Prevention LanzhouGansuChina Xingjiang Uyghur Autonomous Region Center for Disease Control and Prevention UrumqiXinjiangChina Qinhai Institute for Endemic Disease Prevention and Control XiningQinghaiChina Qinghai Provincial People’s Hospital XiningQinghaiChina Tibet Center for Diseases Control and Prevention LhasaTibetChina Inner Mongolia Autonomous Region Center for Diseases Control and Prevention HohhotInner MongoliaChina Ningxia Center for Disease Control and Prevention YinchuanNingxiaChina Yunnan Institute of Parasitic Diseases PuerYunnanChina Shaanxi Provincial Center for Disease Control and Prevention Xi’anShaanxiChina Xinjiang Production and Construction Corps Center for Disease Control and Prevention UrumqiXinjiangChina Henan Provincial Center for Disease Control and Prevention ZhengzhouHenanChina office of epidemiology Chinese Center for Disease Control and PreventionBeijingChina National Health Commission of the People’s Republic of China BeijingChina.

What is already known about this topic?Both alveolar echinococcosis(AE)and cystic echinococcosis are endemic in China,among which alveolar echinococcosis has a very high mortality *** is added by this report?The survey results showed the prevalence and scope of AE in China and identified high-risk groups including children,monks,herdsmen and illiterate *** the same time,all the cases found in the survey(more than 90%of the patients did not go to the hospital for diagnosis and treatment before survey)were promptly diagnosed and *** are the implications for public health practice?This study provides information for the development of a plan for AE prevention and control and for the implementation of interventions targeted to high-risk populations.

关键词： prevention diagnosis mortality

Crystallography of low Z material at ultrahigh pressure:Case study on solid hydrogen

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Matter and Radiation at Extremes 2020年第3期5卷 40-54页

作者： Cheng Ji Bing Li Wenjun Liu Jesse S.Smith Alexander Bjoorling Arnab Majumdar Wei Luo Rajeev Ahuja Jinfu Shu Junyue Wang Stanislav Sinogeikin Yue Meng Vitali B.Prakapenka Eran Greenberg Ruqing Xu Xianrong Huang Yang Ding Alexander Soldatov Wenge Yang Guoyin Shen Wendy L.Mao Ho-Kwang Mao Center for High Pressure Science and technology Advanced Research Beijing 100094China High Pressure Collaborative AccessTeam Geophysical LaboratoryCarnegie Institution of WashingtonArgonneIllinois 60439USA Center for the Study of Matter at Extreme Conditions and Department of Mechanical and Materials Engineering Florida International UniversityMiamiFlorida 33199USA Advanced Photon Source Argonne National LaboratoryLemontIllinois 60439USA HPCAT X-Ray Science DivisionArgonne National LaboratoryLemontIllinois 60439USA MAX IV Laboratory Lund University22100 LundSweden Condensed Matter Theory Group Materials Theory DivisionDepartment of Physics and AstronomyUppsala UniversityUppsala S-75120Sweden Center for Advanced Radiation Sources University of ChicagoChicagoIllinois 60637USA Department of Engineering Sciences and Mathematics Lule°a University of Technology97187 Lule°aSweden Department of Geological Sciences Stanford UniversityStanfordCalifornia 94305USA Stanford Institute for Materials and Energy Sciences SLAC National Accelerator LaboratoryMenlo ParkCalifornia 94025USA

Diamond anvil cell techniques have been improved to allow access to the multimegabar ultrahigh-pressure region for exploring novel phenomena in ***,the onlyway to determine crystal structures of materials above 100 GPa,namely,X-ray diffraction(XRD),especially for lowZ materials,remains nontrivial in the ultrahigh-pressure region,even with the availability of brilliant synchrotron X-ray *** thiswork,we performa systematic study,choosing hydrogen(the lowest X-ray scatterer)as the subject,to understand how to better perform XRD measurements of low Z materials at multimegabar *** techniques that we have developed have been proved to be effective in measuring the crystal structure of solid hydrogen up to 254GPa at room temperature[*** et al.,Nature 573,558–562(2019)].Wepresent our discoveries and experienceswith regard to several aspects of thiswork,namely,diamond anvil selection,sample configuration for ultrahigh-pressure XRDstudies,XRDdiagnostics for low Z materials,and related issues in data interpretation and pressure *** that these methods can be readily extended to other low Z materials and can pave the way for studying the crystal structure of hydrogen at higher pressures,eventually testing structural models of metallic hydrogen.

关键词： ultrahigh solid eventually

Optical Measurement of Photorecombination Time Delays

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Ultrafast Science 2023年第6期3卷 17-24页

作者： Chunmei Zhang Graham Brown Dong Hyuk Ko P.B.Corkum Joint Attosecond Science Laboratory University of Ottawa and National Research Council of Canada25 Templeton StOttawaON K1N 6N5Canada Beijing Institute of technology No.5South StreetZhongguancunHaidian DistrictBeijingChina Max Born Institute Max Born Str.2a12489 BerlinGermany

Recollision physics and attosecond pulse generation meld the precision of optics with collision *** a follow-up to our previous work,we reveal a new direction for the study of electronic structure and multielectron dynamics by exploiting the collision-physics nature of *** show experimentally that,by perturbing recollision trajectories with an infrared field,photorecombination time delays can be measured entirely optically using the Cooper minimum in argon as an *** doing so,we demonstrate the relationship between recollision trajectories and the transition moment coupling the ground and continuum *** particular,we show that recollision trajectories are influenced by their parent ion,while it is commonly assumed they are *** work paves the way for the entirely optical measurement of ultrafast electron dynamics and photorecombination delays due to electronic structure,multielectron interaction,and strong-field-driven dynamics in complex molecular systems and correlated solid-state systems.

关键词： collision entirely dynamics

Compare the epidemiological and clinical features of imported and local COVID-19 cases in Hainan, China

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Infectious Diseases of Poverty 2020年第5期9卷 105-115页

作者： Biao Wu Zi-Ying Lei Kun-Liang Wu Jian-Rong He Hui-Juan Cao Juan Fu Feng Chen Yuan Chen Bao Chen Xiao-Li Zhou Tao Huang Tao Wu Yong-Guo Du Suo-Xian Chen Fu-Rong Xiao Zhi-Liang Gao Jing He Feng Lin Bing-Liang Lin Department of Infectious Diseases Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouChina office of Diseases Control and Prevention Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouChina Department of Infectious Diseases the Third Affiliated Hospital of Sun Yat-Sen University600 Tianhe RoadGuangzhouChina GuangDong Provincial Key Laboratory of Liver Diseases the Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Infectious Diseases The Second Affiliated Hospital of Hainan Medical UniversityHaikouChina Nuffield Department of Women's and Reproductive Health University of OxfordOxfordUK Radiology Department Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouChina Clinical laboratory Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouChina Key Laboratory of Tropical Disease Control(Sun Yat-sen University) Ministry of EducationGuangzhouChina

Background:Effective management of imported cases is an important part of epidemic prevention and *** Province,China reported 168 coronavirus disease 2019(COVID-19),including 112 imported cases on February 19,2020,but successfully contained the epidemic within 1 *** described the epidemiological and clinical characteristics of COVID-19 in Hainan and compared these features between imported and local cases to provide information for other international epidemic ***:We included 91 patients(56 imported and 35 local cases)from two designated hospitals for COVID-19 in Haikou,China,from January 20 to February 19,*** on the demographic,epidemiological,clinical and laboratory characteristics were extracted from medical *** were followed until April 21,2020,and the levels of antibodies at the follow-ups were also analysed by the Wilcoxon matched-pairs signed ranks ***:Of the 91 patients,78(85.7%)patients were diagnosed within the first three weeks after the first case was identified(Day 1:Jan 22,2020),while the number of local cases started to increase during the third week No new cases occurred after Day *** and cough were two main clinical *** total,15(16.5%)patients were severe,14(15.4%)had complicated infections,nine(9.9%)were admitted to the intensive care unit,and three *** median duration of viral shedding in feces was longer than that in nasopharyngeal swabs(19 days vs 16 days,P=0.007).Compared with local cases,imported cases were older and had a higher incidence of fever and concurrent *** was no difference in outcomes between the two *** was positive in 92.8%patients(77/83)in the follow-up at week 2 after discharge,while 88.4%patients(38/43)had a reduction in IgG levels in the follow-up at week 4 after discharge,and the median level was lower than that in the follow-up at week 2(10.95 S/Cut Off(S/CO)vs 15.02 S/CO,P<0.001).Conclusion:Imported cases were more severe than

关键词： Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus 2 Epidemiology Clinical features Prevention and control

Antioxidant Activities and Characterization of Polyphenols from Selected Northern Thai Rice Husks: Relation with Seed Attributes

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Rice science 2023年第2期30卷 148-159,I0039页

作者： Jiratchaya WISETKOMOLMAT Chaiwat ARJIN Surat HONGSIBSONG Warintorn RUKSIRIWANICH Chutamat NIWAT Pimsiri TIYAYON Sansanee JAMJOD Supapohn YAMUANGMORN Chanakan PROM-U-THAI Korawan SRINGARM Department of Animal and Aquatic Sciences Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand School of Health Science Research Research Institute for Health SciencesChiang Mai UniversityChiang Mai 50200Thailand Department of Pharmaceutical Sciences Faculty of PharmacyChiang Mai UniversityChiang Mai 50200Thailand Food Science and technology Program School of Agro-IndustryMae Fah Luang UniversityChiang Rai 57100Thailand School of Agricultural Resources Chulalongkorn UniversityBangkok 10330Thailand Agronomy Division Department of Plant and Soil SciencesFaculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Lanna Rice Research Center Chiang Mai UniversityChiang Mai 50200Thailand Cluster of Research and Development of Pharmaceutical and Natural Products Innovation for Human or Animal Chiang Mai UniversityChiang Mai 50200Thailand

Rice production generates a significant amount of agricultural waste. This study aimed to give results related to the existence of antioxidant phenols in agricultural waste of selected Northern Thai rice varieties. The antioxidant activities, contents of total flavonoids and phenolic compounds in the ethanolic rice husk extract were evaluated. The highest antioxidant activities were found in the variety PES1CMU, with 2,2’-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid and 2,2-diphenyl-1-picrylhydrazyl as 679.66 and 4.16 mmol/(L·g) trolox equivalent, respectively, ferric reducing antioxidant power as 0.87 mmol/(L·g) Fe2+, total phenolic content as 29.90 mmol/(L·g) gallic acid and total flavonoid content as 12.16 mg/g catechin equivalent. Polyphenol compounds were identified mainly by standard polyphenols using the liquid chromatography mass spectrometry, with the highest contents of phytic acid, o-coumaric acid, naringin and kaempferol. The non-glutenous and wetland ecotypes of rice husk samples were the richest in antioxidant activities and polyphenol contents characterized by using principal component analysis. The glutenous rice husk contained higher antioxidant activities than the rest. Interestingly, quercetin is a significant phenolic compound that positively correlated with the overall antioxidant activities of rice husk. This finding will be relevant for future application of rice husk antioxidant components in the production of functional ingredients as well as for the food and pharmaceutical industries.

关键词： antioxidant agri-waste polyphenol rice husk seed characteristic Thai rice

Retraction:Macrophage involvement in the pathological evolution of ulcerative colitis-associated colon cancer and progress of related traditional Chinese medicine drug interventions

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Traditional Medicine Research 2023年第9期8卷 72-73页

作者： Jun-Yu Ke Jin-Bin Song Long Li Zhen-Fan He Zhuo-Jian Huang Zheng-Lin Liu Gui-Rong Chen Su-Ru Wen Heng-Li Zhou Hui-Lin Ma Qun Du Yong-Qiang Wu Yan-Wu Li Xin-Lin Chen School of Basic Medical Sciences Guangzhou University of Chinese MedicineGuangzhou 510006China Department of Surgery Gaozhou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese MedicineGaozhou 525200China Science and technology Innovation Center Guangzhou University of Chinese MedicineGuangzhou 510405China The First Clinical Medical College Guangzhou University of Chinese MedicineGuangzhou 510405China

Traditional Medicine Research has retracted this article upon the request of the editor-in-chief and academic *** June 5,2023,we received a complaint regarding possible picture plagiarism within the article,which promoted the decision to retract this *** a comprehensive examination,it was determined that the content depicted in this article's pictures was identical to that found in another published ***,the editorial office determined that retracting the article was necessary.

关键词： involvement colon editor

The effects of different travel modes and travel destinations on COVID-19 transmission in global cities

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Science Bulletin 2022年第6期67卷 588-592,M0003页

作者： Rui Zhu Luc Anselin Michael Batty Mei-Po Kwan Min Chen Wei Luo Tao Cheng Che Kang Lim Paolo Santi Cheng Cheng Qiushi Gu Man Sing Wong Kai Zhang Guonian Lü Carlo Ratti Department of Land Surveying and Geo-Informatics the Hong Kong Polytechnic UniversityHong KongChina Key Laboratory of Virtual Geographic Environment(Ministry of Education) Nanjing Normal UniversityNanjing 210023China Senseable City Laboratory Future Urban Mobility IRGSingapore-MIT Alliance for Research and TechnologySingapore 138602Singapore Center for Spatial Data Science Division of the Social SciencesUniversity of ChicagoChicago IL 60637USA School of Geography Science Nanjing Normal UniversityNanjing 210023China Centre for Advanced Spatial Analysis Faculty of the Built EnvironmentUniversity College LondonLondon WC1E 6BTUK Department of Geography and Resource Management the Chinese University of Hong KongHong KongChina Institute of Space and Earth Information Science the Chinese University of Hong KongHong KongChina Department of Human Geography and Spatial Planning Utrecht UniversityUtrecht 3584 CSNetherlands State Key Laboratory Cultivation Base of Geographical Environment Evolution Nanjing 210023China Department of Geography National University of SingaporeSingapore 117570Singapore SpaceTimeLab Department of CivilEnvironmental and Geomatic EngineeringUniversity College LondonLondon WC1E 6BTUK Department of Clinical Translational Research Singapore General HospitalSingapore 169856Singapore Division of Clinical Immunology and Transfusion Medicine Department of Laboratory MedicineKarolinska InstitutetStockholm 17177Sweden Senseable City Laboratory Department of Urban Studies and PlanningMassachusetts Institute of TechnologyCambridgeMA 02139USA Istituto di Informatica e Telematica del CNR Pisa 56124Italy Department of System Science Institute of High Performance Computing Agency for ScienceTechnology and ResearchSingapore 138632Singapore Department of Tourism Studies School of HumanitiesSoutheast UniversityNanjing 210096China

The international community has made significant efforts to flatten the COVID-19 curve,including predicting transmission[1,2],executing unprecedented global lockdowns and social distancing[3,4],promoting the wearing of facemasks and social distancing measures[5],and isolating confirmed cases and contacts[6].Because of the adverse consequences of these lockdown measures[7],many cities have reopened so they can rebuild their ***,as mobility has gradually returned towards normal,imported cases from unknown sources have disrupted the recovery situation,and cities are continually at high risk of new waves of infection[8,9]since airborne transmission is the dominant transmission route[10].

关键词：多变量时间序列疫情传播出行方式谷歌公司交通出行病毒传播出行行为大城市

Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

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Synthetic and Systems Biotechnology 2020年第1期5卷 11-18页

作者： Tadas Jakočiūnas Andreas K.Klitgaard Eftychia Eva Kontou Julie Bang Nielsen Emil Thomsen David Romero-Suarez Kai Blin Christopher J.Petzold Jennifer W.Gin Yaojun Tong Charlotte Held Gotfredsen Pep Charusanti Rasmus J.N.Frandsen Tilmann Weber Sang Yup Lee Michael K.Jensen Jay D.Keasling The Novo Nordisk Foundation Center for Biosustainability Technical University of DenmarkKgs.LyngbyDenmark Joint BioEnergy Institute EmeryvilleCAUSA Biological Systems&Engineering Division Lawrence Berkeley National LaboratoryBerkeleyCAUSA Department of Chemical and Biomolecular Engineering&Department of Bioengineering University of California BerkeleyCAUSA Center for Synthetic Biochemistry Institute for Synthetic BiologyShenzhen Institutes for Advanced TechnologiesShenzhenChina Department of Chemistry Technical University of DenmarkKgs.LyngbyDenmark Department of Biotechnology and Biomedicine Technical University of DenmarkKgs.LyngbyDenmark Department of Chemical and Biomolecular Engineering(BK21 Plus Program) Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon34141Republic of Korea

To accelerate the shift to bio-based production and overcome complicated functional implementation of natural and artificial biosynthetic pathways to industry relevant organisms,development of new,versatile,bio-based production platforms is *** we present a novel yeast-based platform for biosynthesis of bacterial aromatic *** platform is based on a synthetic polyketide synthase system enabling a first demonstration of bacterial aromatic polyketide biosynthesis in a eukaryotic host.

关键词： Natural products Synthetic biology Aromatic polyketides CRISPR/Cas9 Polyketide Production platform in eukaryotes Metabolic engineering Biotechnology