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Highly efficient Cherenkov radiation generation in the irregular point of hollow-core photonic crystal fiber

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Chinese Physics B 2012年第11期21卷 222-226页

作者：申向伟苑金辉桑新柱余重秀饶兰夏民韩颖夏长明侯蓝田 state Key laboratory of Information Photonics and Optical Communications Beijing University of Posts&Telecommunications Institute of Infrared Optical Fibers&sensors

Highly efficient Cherenkov radiation （CR） is generated by the soliton self-frequency shift （SSFS） in the irregular point of a hollow-core photonic crystal fiber （HC-PCF） in our laboratory. The impacts of pump power and wavelength on the CR are investigated, and the corresponding nonlinear processes are discussed. When the average power of the 120 fs pump pulse increases from 500 mW to 700 mW, the Raman soliton shifts from 2210 nm to 2360 nm, the output power of the CR increases by 2.3 times, the maximum output power ratio of the CR at 539 nm to that of the residual pump is calculated to be 24.32：1, the width of the output optical spectrum at the visible wavelength broadens from 35 nm to 62 nm, and the conversion efficiency η of the CR in the experiment can be above 32%.

关键词： Cherenkov radiution hollow-core photonic crystal fiber soliton self-frequency shift

Carbon dots-based dopamine sensors: Recent advances and challenges

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Chinese Chemical Letters 2024年第12期35卷 123-131页

作者： Chenghao Liu Xiaofeng Lin Jing Liao Min Yang Min Jiang Yue Huang Zhizhi Du Lina Chen Sanjun Fan Qitong Huang Key laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province Key Laboratory of Biomedical Sensors of Ganzhou School of Medical and Information EngineeringSchool of Pharmacy Scientific Research Center Gannan Medical University Department of Chemistry and Biochemistry The Ohio State University

Dopamine, a pivotal excitatory neurotransmitter, plays a crucial role in metabolic, cardiovascular, renal,central nervous, and endocrine systems. Abnormal dopamine within the human body can cause various diseases. Therefore, the precise quantification of dopamine levels, both in vivo and in vitro, holds paramount significance for clinical applications and physiological investigations. Carbon dots(CDs) exhibit a plethora of remarkable properties, including a substantial specific surface area, robust electrical conductivity, commendable biocompatibility, minimal toxicity, and high photostability. Considering these unique characteristics, CDs demonstrate substantial potential for fluorescent sensors, colorimetric sensors,and electrochemical sensors for dopamine detection. This review systematically examined the challenges and prospects for the utilization of CDs-based fluorescent sensors, electrochemical biosensors, and colorimetric sensors for monitoring dopamine levels in recent years. These findings unveil promising avenues for further advancements in the field of dopamine detection.

关键词： Dopamine Carbon dots Fluorescent sensors Colorimetric sensors Electrochemical sensors

Neurochip Based on Light-addressable Potentiometric Sensor

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稀有金属材料与工程 2006年第A3期35卷 413-416页

作者： Qingjun Liu Hua Cai Ying Xu Lifeng Qin Lijiang Wang Ping Wang Biosensor National Special laboratory Key Laboratory of Biomedical Engineering of Education MinistryDepartment of Biomedical Engineering Zhejiang University Hangzhou 310027 China state Key laboratory of Transducer Technology Chinese Academy of Sciences Shanghai 200050 China

A novel neurochip based on light addressable potentiometric sensor (LAPS) is *** its light addressable *** problems of the limitations of restricted discrete active sites of current neurochips,such as microelectrode array and field effect transistor array can be settled *** on the theoretical analysis of the interface between cells and LAPS,spontaneously discharges of hippocampal neurons induced by Mg~ 2+)-free media treatment were recorded by *** results demonstrate that this kind of neurochip has potential to monitor electrophysiology of cultured cells in a non-invasive way.

关键词： neurochip cell-based biosensor hippocampal neurons light-addressable potentiometric sensor

Automatic Monitoring Electronic Tongue with MEAs for Environmental Analysis

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稀有金属材料与工程 2006年第A3期35卷 381-384页

作者： Shaofang Zou Hong Men Yi Li Yinping Wang Ping Wang Biosensor National Special laboratory Key Laboratory of Biomedical Engineering of Education Ministry Department of Biomedical Engineering Zhejiang University Hangzhou 310027 China state Key laboratory of Transducer Technology Chinese Academy of Sciences Shanghai 200050 China

An automatic monitoring electronic tongue based on differential pulse stripping voltammetry (DPSV) was developed for heavy metals *** detections of trace Zn(Ⅱ),Cd(Ⅱ),Pb(Ⅱ),Cu(Ⅱ),Fe(Ⅲ) and Cr(Ⅲ) in water samples were performed with three electrochemical *** sensor chip combined a silicon-based Hg-coated Au microelectrode array (MEA) as the working electrode on one side with an Ag/AgCl reference electrode and a Pt counter electrode on the other *** a computer controlled multipotentiostat,pumps and valves,the electronic tongue realized in-situ real-time detection of the six metals mentioned above at parts-per-billion level without manual operation.

关键词： electronic tongue heavy metals automatic monitoring microelectrode array multipotentiostat

Room-Temperature Processed Amorphous ZnRhCuO Thin Films with p-Type Transistor and Gas-Sensor Behaviors

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Chinese Physics Letters 2020年第9期37卷 108-111页

作者： Bojing Lu Rumin Liu Siqin Li Rongkai Lu Lingxiang Chen Zhizhen Ye Jianguo Lu state Key laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Key laboratory for biomedical Engineering of Ministry of Education College of Biomedical Engineering and Instrument ScienceZhejiang UniversityHangzhou 310027China

We examine an amorphous oxide semiconductor(AOS)of *** a-ZnRhCuO films are deposited at room temperature,having a high amorphous quality with smooth surface,uniform thickness and evenly distributed elements,as well as a high visible transmittance above 87%with a wide bandgap of 3.12 *** a-ZnRhCuO films as active layers,thin-film transistors(TFTs)and gas sensors are *** TFT behaviors demonstrate the p-type nature of a-ZnRhCuO channel,with an on-to-off current ratio of^1×10^3 and field-effect mobility of0.079 cm^2 V^-1s^-*** behaviors of gas sensors also prove that the a-ZnRhCuO films are of p-type *** achievements relating to p-type a-ZnRhCuO films at room temperature with TFT devices may pave the way to practical applications of AOSs in transparent flexible electronics.

关键词： amorphous transparent films

Polarization-dependent efficient Cherenkov radiation at visible wavelengths in hollow-core photonic crystal fiber cladding

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Chinese Physics B 2013年第1期22卷 222-225页

作者：申向伟苑金辉桑新柱余重秀饶岚夏民韩颖夏长明侯蓝田吴中超何晓亮 The 26th Institute of China Electronics Technology Corporation state Key laboratory of Information Photonics and Optical Communications Beijing University of Posts & Telecommunications Institute of Infrared Optical Fibers & sensors

Efficient Cherenkov radiation （CR） is experimentally generated by a soliton self-frequency shift （SSFS） in a knot of hollow-core photonic crystal fiber （HC-PCF）. When the angle of the half-wave plate is rotated from 0° to 45°, the Raman soliton shifts from 2227 to 2300 nm, the output power of the CR increases 8.15 times, and the maximum output power ratio of the CR at 556 nm to the residual pump is estimated to be 20：1. The width of the output optical spectrum at visible wavelengths broadens from 25 to 45 nm, and the conversion efficiency of the CR can be above 28%. Moreover, the influences of the pump polarization and wavelength on the CR are studied, and the corresponding nonlinear processes are discussed.

关键词： polarization-dependent Cherenkov radiation hollow-core photonic crystal fiber (HC-PCF)

A Novel Structure of LAPS Array for Cell-Based Biosensor

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稀有金属材料与工程 2006年第A3期35卷 51-54页

作者： Ying Xu Hua Cai Qingjun Liu Lifeng Qin Lijiang Wang Ping Wang Biosensor National Special laboratory Key Laboratory of Biomedical Engineering of Education Ministry Department of Biomedical Engineering Zhejiang University Hangzhou 310027 China state Key Lab of Transducer Technology Chinese Academy of Sciences Shanghai 200050 China

The light-addressable potentiometric sensor (LAPS) is a semiconductor-based cellular biosensor with an electrolyte-insulator-semiconductor (EIS) *** depositing biocompatible layers on the sensing surface for cell culture, it can be used to detect bioelectrical parameters of *** characteristic curve for photocurrent versus applied bias voltage to the system shows a current-voltage curve (Ⅰ-Ⅴcurve).This technique can be used to detect the action potential changes towards different drugs based on the bias voltage dependence of an optical current,and provides a dynamic system by scanning light beam at the very cell on the sensor *** LAPS overcomes the limitation of recording sites,but high spatial resolution and sensitivity are also *** paper discussed a novel structure of LAPS array for extracellular monitoring to decrease potential noise *** characteristics of active recording array areas and cell culture conditions are measured.

关键词： light-addressable potentiometric sensor array LAPS sensitivity cell-based biosensor

Cell-Based Biosensors and Bio-MEMS for Its New Applications

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稀有金属材料与工程 2006年第A3期35卷 47-50页

作者： Ping Wang Biosensor National Special laboratory Key Laboratory of Biomedical Engineering of Education Ministry Department of Biomedical Engineering Zhejiang University Hangzhou 310027 China

This paper reviews a novel cell-based biosensor and Bio-MEMS which incorporate living cells as sensing elements that convert a change in immediate environment to signals conducive for *** is characterized with high sensitivity,excellent selectivity and fast response and have been implemented for a number of applications ranging from pharmaceutical screening to environmental pollutant *** paper also introduces our recent work about Light-Addressable Potentiometric sensors (LAPS),Field Effect Transistor (FET),Micro-Electrode Array sensors (MEAS) and Bio-MEMS for detecting the changes of concentration of extracellular ions and the action potential of living cell under effect of drugs and environmental ***, the paper gives some prospects of cell-based biosensors in the future.

关键词： cell-based sensors Bio-MEMS biosensors LAPS FET MEAs

Ultraviolet and mid-infrared continuum generation by cross-phase modulation between red-shifted solitons and blue-shifted dispersive waves in a photonic crystal fiber

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Chinese Physics B 2012年第7期21卷 337-342页

作者：申向伟苑金辉桑新柱余重秀饶岚忻向军夏民韩颖夏长明侯蓝田 state Key laboratory of Information Photonics and Optical Communications Beijing University of Posts&Telecommunications School of Information and Communication Engineering Beijing University of Posts&Telecommunications Institute of Infrared Optical Fibers&sensors

Using a photonic crystal fiber with a zero dispersion wavelength of the fundamelItal mode at 780 nm designed and fabricated in our lab, the ultraviolet and mid-infrared continua are generated by cross-phase modulation between red-shift solitons and blue-shift dispersive waves. The dependences of continuum on the pump power and wavelength are investigated. With the pump working at 820 nm, when the pump power increases froul 300 to 500 mW, the bandwidths of ultraviolet and mid-infrared continua change from 80 to 140 nm and 100 to 200 nm, respectively. The wavelength of ultraviolet continuum is below 246 nm, and the wavelength of mid-infrared continuum exceeds 2500 nm. Moreover, the influences of pump power on wavelength and conversion efficiency of different parts of continua are also demonstrated.

关键词： photonic crystal fiber (PCF) ultraviolet and mid-infrared continuum fundamentalmode soliton self-frequency shift