检索结果-南通市图书馆

The regulatory network and critical factors promoting programmed cell death during embryogenesis

Journal of Integrative Plant Biology 2025年第1期67卷 55-70页

作者： An Luo Ce Shi Pan Luo Zifu Zhao Meng-Xiang Sun college of life sciences Yangtze UniversityJingzhou 434023China state key laboratory of Hybrid Rice College of Life SciencesWuhan UniversityWuhan 430072China

Programmed cell death(PCD)is essential for animal and plant ***,the knowledge of the mechanism regulating PCD in plants remains limited,largely due to technical ***,we determined that the protease NtCP14 could trigger PCD in the embryonic suspensor of tobacco(Nicotiana tabacum),providing a unique opportunity to overcome the limitations by creating synchronous two-celled proembryos with ongoing PCD for transcriptome analysis and regulatory factor ***,we performed comparative transcriptome analysis using isolated two-celled proembryos and explored the potential regulatory network underlying NtCP14-triggered *** phytohormones,calcium,microtubule organization,the immunity system,soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins,long non-coding RNAs and alternative splicing are addressed as critical factors involved in the early stage of suspensor *** thought to play crucial roles in suspensor PCD are ***,decreased antioxidant gene expression and increased reactive oxygen species(ROS)levels during suspensor PCD suggest a critical role for ROS signaling in the initiation of NtCP14-triggered ***,five genes in the regulatory network are recommended as immediate downstream elements of ***,our analysis outlines an overall molecular network underlying protease-triggered PCD and provides a reliable database and valuable clues for targeting elements immediately downstream of NtCP14 to overcome technical bottlenecks and gain deep insight into the molecular mechanism regulating plant PCD.

关键词： programmed cell death protease reactive oxygen species suspensor transcriptome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hollow MnO_(2)-based multifunctional nanoplatform for enhanced tumor chemodynamic therapy

引用

Science China Materials 2025年第1期68卷 292-302页

作者： Dejie Ge Debao Ren Yamin Duan Xuan Luo Shuailin He Wenjun Qin Fei Wang Wen Yin Lixin Ma Yong Yang Cheng Zhang state key laboratory of Biocatalysis and Enzyme Engineering College of Life SciencesHubei UniversityWuhan 430062China Hubei key laboratory of Industrial Biotechnology College of Life SciencesHubei UniversityWuhan 430062China college of Health Science and Engineering Hubei UniversityWuhan 430062China School of Materials Science and Engineering Hubei UniversityWuhan 430062China

The inherent tumor microenvironment(TME)of hypoxia and high glutathione(GSH)hinders the production of reactive oxygen species(ROS),yet which are crucial roles to make the oxygen-independent chemodynamic therapy(CDT)***,we constructed hyaluronic acid(HA)-modified and peroxymonosulfate(PMS)-loaded hollow manganese dioxide(HMn)nanoparticles for not only TME-response drug release but also the distinct ROS donors to strengthen *** enriched in the tumor site,the prepared nanotheranostic agent(HA@HMn/PMS)depleted local GSH to reduce MnO_(2) to Mn^(2+),followed by generating•OH andSO_(4)^(−)through Fenton-like reaction and activation of PMS,*** bring in of•SO_(4)^(−),a rare radical possessing exceptional oxidizing ability and oxygen-independent property,breaks the limitations of traditional ROS and causes serious damage to tumor *** a xenograft mouse tumor model,detailed studies demonstrated that HA@HMn/PMS can significantly inhibit tumor *** work inspires the enormous potential of CDT in investigating the application of multifunctional nanosystems by combining the consumption of GSH and the synergistic effect of multiple radicals in oncotherapy.

关键词： hollow manganese dioxide sulfate radical glutathione chemodynamic therapy tumor therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Combined biochar and wheat-derived endophytic bacteria reduces cadmium uptake in wheat grains in a metal-polluted soil

引用

Journal of Environmental sciences 2025年第1期147卷 165-178页

作者： Zhihui Xiong Yaping Wang Linyan He Qi Sheng Xiafang Sheng college of life sciences Key Laboratory of Agricultural and Environmental MicrobiologyMinistry of AgricultureNanjing Agricultural UniversityNanjing 210095China

In this study,two wheat-derived cadmium(Cd)-immobilizing endophytic Pseudomonas paralactis M14 and Priestia megaterium R27 were evaluated for their effects on wheat tissue Cd uptake under hydroponic ***,the impacts of the biochar(BC),M14+R27(MR),and BC+MR treatments on wheat Cd uptake and the mechanisms involved were investigated at the jointing,heading,and mature stages of wheat plants under field-plot conditions.A hydroponic experiment showed that the MR treatment significantly decreased the above-ground tissue Cd content compared with theM14 or R27 *** BC+MRtreatment reduced the grain Cd content by 51.5%-67.7%and Cd translocation factor at the mature stage of wheat plants and increased the organic matter-bound Cd content by 31%-75%in the rhizosphere soils compared with the BC or MR *** with the BC or MR treatment,the relative abundances of the biomarkers associated with Gemmatimonas,Altererythrobacter,Gammaproteobacteria,Xanthomonadaceae,Phenylobacterium,and Nocardioides in the BC+MR-treated rhizosphere microbiome decreased and negatively correlated with the organic matter-bound Cd *** the BC+MR-treated root interior microbiome,the relative abundance of the biomarker belonging to Exiguobacterium increased and negatively correlated with the Cd translocation factor,while the relative abundance of the biomarker belonging to Pseudonocardiaceae decreased and positively correlated with the Cd translocation *** findings suggested that the BC+MR treatment reduced Cd availability and Cd transfer through affecting the abundances of these specific biomarkers in the rhizosphere soil and root interior microbiomes,leading to decreased wheat grain Cd uptake in the contaminated soil.

关键词： Cd-immobilizing endophytic bacteria Cd-contaminated soil Biochar+endophytic bacteria Grain Cd uptake Specific biomarkers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The effects of 17β-trenbolone and bisphenol A on sexual behavior and social dominance via the hypothalamic-pituitary-gonadal axis in male mice

引用

Journal of Environmental sciences 2025年第5期151卷 54-67页

作者： Xiang Zuo Minghe Sun Huijuan Bai Shuhui Zhang Jialu Luan Qian Yu Zhenhua Fu Qili Zhao Mingzhu Sun Xin Zhao Xizeng Feng college of life Science State Key Laboratory of Medicinal Chemical BiologyThe Key Laboratory of Bioactive MaterialsMinistry of EducationNankai UniversityTianjin 300071China Institute of Robotics&Automatic Information System College of Artificial IntelligenceNankai UniversityTianjin 300071China

17β-Trenbolone(17-TB)is well documented as an environmental endocrine disruptor in aquatic biological studies,but its effects on mammals remain poorly ***,17-TB acts as a hormone with properties similar to testosterone,and the consequences of juvenile exposure on adult social behavior remain *** A(BPA)acts as an estrogen-like hormone,compared to ***-week-old male Balb/c mice were exposed orally to 17-TB(100μg/(kg·day))and BPA(4 mg/(kg·day))for 28 *** of social interactions and a three-chamber test showed that 17-TB increased virility in male mice,intensified both male and female sexual behavior,and attracted and accepted female *** also increased social dominance through tube tests inmalemice and markedly activated the c-Fos^(+)immune response in themedial prefrontal cortex(mPFC)and basal amygdala(BLA).ELISA data showed that 17-TB and BPA exposure significantly affected serum gonadotropin-releasing hormone(GnRH),growth hormone(GH),estradiol(E2),and luteinizing hormone(LH)levels,as well as testicular lesions and androgen receptor(ARβ)and estrogen receptor(ERα)*** transcriptomic analysis further confirmed that could disrupt steroid synthesis and linoleic acid-related biometabolic *** findings suggest the influence of 17-TB and BPA exposure on sexual behavior and fertility in male mice,possibly through modulation of the hypothalamic-pituitary-gonadal *** study provides insights relevant to human reproductive health and neuro-social behavioral research,and the potential risk of environmental disturbances should not be overlooked.

关键词： 17β-Trenbolone(17-TB) Bisphenol A(BPA) hypothalamic-pituitary-gonadal axis(HPG) Sex hormones Social dominance Sexual behavior

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Disruption of Energy Metabolism and Reactive Oxygen Species Homeostasis in Honglian Type-Cytoplasmic Male Sterility(HL-CMS)Rice Pollen

引用

Rice science 2025年第1期32卷 81-93,I0056-I0058页

作者： WANG Mingyue ZHAO Weibo FENG Xiaoya CHEN Yi LI Junhao FU Jinmei YAN Yingchun CHU Zhaohui HUANG Wenchao state key laboratory of Hybrid Rice Key Laboratory for Research and Utilization of Heterosis in Indica Ricethe Ministry of Agriculture and Rural Affairs/Department of GeneticsCollege of Life SciencesWuhan UniversityWuhan 430072China

Honglian type-cytoplasmic male sterility(HL-CMS)is caused by the inter-communication between the nucleus and ***,the mechanisms by which sterility genes regulate metabolic alterations and changes in mitochondrial morphology in the pollen of HL-CMS remain *** this study,we compared the morphological differences between the pollen of the male sterile line YA and the near-isogenic line NIL-Rf6 using hematoxylin-eosin staining and 4ʹ,6-diamidino-2-phenylindole(DAPI)***-CMS is characterized by gametophytic sterility,where the aborted pollen grains are empty,and the tapetal layer remains *** electron microscopy was employed to observe mitochondrial morphological changes at the microspore stage,revealing significant mitochondrial alterations,characterized by the formation of'large spherical mitochondria',occurred at the binucleate stage in the YA ***,metabolomics analysis revealed decreased levels of metabolites associated with the carbohydrate and flavonoid ***,the decrease in flavonoids was found to contribute to an elevation in reactive oxygen species(ROS)***,we propose a model in which rice fertility is modulated by the levels of pollen carbohydrates and flavonoid metabolites,with impaired mitochondrial energy production and reduced flavonoid biosynthesis as the main causes of ROS accumulation and pollen abortion in rice.

关键词： cytoplasmic male sterility pollen reactive oxygen species rice mitochondrial metabolite

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fine control of growth and thermotolerance in the plant response to heat stress

引用

Journal of Integrative Agriculture 2025年第2期24卷 409-428页

作者： Yulong Zhao Song Liu Kaifeng Yang Xiuli Hu Haifang Jiang state key laboratory of Wheat&Maize Crop Science/college of life sciences Henan Agricultural University

Global warming impacts plant growth and development, which in turn threatens food security. Plants can clearly respond to warm-temperature(such as by thermomorphogenesis) and high-temperature stresses. At the molecular level, many small molecules play crucial roles in balancing growth and defense, and stable high yields can be achieved by fine-tuning the responses to external stimuli. Therefore, it is essential to understand the molecular mechanisms underlying plant growth in response to heat stress and how plants can adjust their biological processes to survive heat stress conditions. In this review, we summarize the heat-responsive genetic networks in plants and crop plants based on recent studies. We focus on how plants sense the elevated temperatures and initiate the cellular and metabolic responses that allow them to adapt to the adverse growing conditions. We also describe the trade-off between plant growth and responses to heat stress. Specifically, we address the regulatory network of plant responses to heat stress, which will facilitate the discovery of novel thermotolerance genes and provide new opportunities for agricultural applications.

关键词： heat stress signal transduction tolerance mechanisms trade-off

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The MON1–CCZ1 complex plays dual roles in autophagic degradation and vacuolar protein transport in rice

引用

Journal of Integrative Plant Biology 2025年第1期67卷 35-54页

作者： Binglei Zhang Yihua Wang Yun Zhu Tian Pan Haigang Yan Xin Wang Ruonan Jing Hongming Wu Fan Wang Yu Zhang Xiuhao Bao Yongfei Wang Pengcheng Zhang Yu Chen Erchao Duan Xiaohang Han Gexing Wan Mengyuan Yan Xiejun Sun Cailin Lei Zhijun Cheng Zhichao Zhao Ling Jiang Yiqun Bao Yulong Ren Jianmin Wan state key laboratory of Crop Gene Resources and Breeding National Key Facility for Crop Gene Resources and Genetic ImprovementInstitute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China college of life sciences Nanjing Agricultural UniversityNanjing 210095China state key laboratory of Crop Genetics&Germplasm Enhancement and Utilization Nanjing Agricultural UniversityNanjing 210095China Zhongshan Biological Breeding laboratory Nanjing 210095China

Autophagy is a highly conserved cellular program in eukaryotic cells which mediates the degradation of cytoplasmic components through the lysosome,also named the vacuole in ***,the molecular mechanisms underlying the fusion of autophagosomes with the vacuole remain ***,we report the functional characterization of a rice(Oryza sativa)mutant with defects in storage protein transport in endosperm cells and accumulation of numerous autophagosomes in root *** and immunocytochemical experiments showed that this mutant exhibits a defect in the fusion between autophagosomes and *** mutant harbors a loss-of-function mutation in the rice homolog of Arabidopsis thaliana MONENSIN SENSITIVITY1(MON1).Biochemical and genetic evidence revealed a synergistic interaction between rice MON1 and AUTOPHAGY-RELATED 8a in maintaining normal growth and *** addition,the rice mon1 mutant disrupted storage protein sorting to protein storage ***,quantitative proteomics verified that the loss of MON1 function influenced diverse biological pathways including autophagy and vacuolar transport,thus decreasing the transport of autophagic and vacuolar cargoes to ***,our findings establish a molecular link between autophagy and vacuolar protein transport,and offer insights into the dual functions of the MON1–CCZ1(CAFFEINE ZINC SENSITIVITY1)complex in plants.

关键词： autophagic degradation MON1–CCZ1 Rab7 rice vacuolar trafficking

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Green revolution gene drives adaptation of Arabidopsis to the extremely high altitude

引用

Science China life sciences 2025年第03期 859-870页

作者： Xing-Hui Hou Yong-Chao Xu Tianshu Sun Yan-Bo Gong Xin-Tong Li Guang-Teng Jin Yu-Tao Bian Yi-Ni Liu Juan Jiang Xiao-Min Niu Hongya Gu Ya-Long Guo state key laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences China National Botanical Garden state key laboratory for Protein and Plant Gene Research School of Life Sciences Peking University college of life sciences University of Chinese Academy of Sciences

To elucidate the process of adaptation, particularly the traits subject to natural selection and the molecular mechanisms underlying their natural variation, is one of the primary objectives of evolutionary biology. The uplifted landscape offers an excellent framework for understanding how organisms adapt to dramatic climatic gradients. To investigate the genetic basis of plant adaptation to the extremely high altitude, we first compared the genomic and phenotypic variations of two closely related Arabidopsis thaliana accessions from high altitude(Xizang, also known as “Tibet”) and low altitude(Yunnan), respectively. The Xizang population represents a relict group characterized by a small effective population size. Notably, the Xizang genome has more transposable elements(TEs) and more gene loss-offunction(Lo F) mutations. Differentially expressed genes were enriched in biological processes of cellular response to oxygen-containing compound, regulation of defense response, and response to light intensity. Intriguingly, the phenotypic selection analysis revealed that silique density was under natural selection. Furthermore, we genetically mapped and validated that the Lo F mutation of GA20ox1, the homologous gene of green revolution in rice, resulted in a higher silique density in Xizang Arabidopsis. Given that GA20ox1 is linked to Arabidopsis adaptation to the Alps Mountains, its parallel evolution plays an important role in the adaptation to Alpine habitats. Overall,our results highlight that identifying adaptive traits and elucidating the molecular mechanisms underlying natural variation of these traits is crucial for unraveling the mystery of adaptive evolution and has significant implications for crop breeding.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recognition of a salivary effector by the TNL protein RCSP promotes effector-triggered immunity and systemic resistance in Nicotiana benthamiana

引用

Journal of Integrative Plant Biology 2025年第1期67卷 150-168页

作者： Weiwei Rao Tingting Ma Jiayuan Cao Yajun Zhang Sisi Chen Shu Lin Xiaoxiao Liu Guangcun He Li Wan key laboratory of Plant Design CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China National key laboratory of Hybrid Rice College of Life SciencesWuhan UniversityWuhan 430072China University of Chinese Academy of sciences Beijing 100049China

Insects secret chemosensory proteins(CSPs)into plant cells as potential effector proteins during *** molecular mechanisms underlying how CSPs activate plant immunity remain largely *** show that CSPs from six distinct insect orders induce dwarfism when overexpressed in Nicotiana ***-mediated transient expression of Nilaparvata lugens CSP11(NlCSP11)triggered cell death and plant dwarfism,both of which were dependent on ENHANCED DISEASE SUSCEPTIBILITY 1(EDS1),N requirement gene1(NRG1)and SENESCENCE-ASSOCIATED GENE 101(SAG101),indicating the activation of effector-triggered immunity(ETI)in *** of NlCSP11 led to stronger systemic resistance against Pseudomonas syringae DC3000 lacking effector HopQ1-1 and tobacco mosaic virus,and induced higher accumulation of salicylic acid(SA)in uninfiltrated leaves compared to another effector XopQ that is recognized by a Tollinterleukin-1 receptor(TIR)domain nucleotidebinding leucine-rich repeat receptor(TNL)called ROQ1 in ***,NlCSP11-induced dwarfism and systemic resistance,but not cell death,were abolished in *** transgenic line expressing the SA-degrading enzyme Nah *** large-scale virus-induced gene silencing screening,we identified a TNL protein that mediates the recognition of CSPs(RCSP),including aphid effector MP10 that triggers resistance against aphids in ***,bimolecular fluorescence complementation and Alpha Fold2 prediction unveiled an interaction between NlCSP11 and ***,RCSP does not contain the conserved catalytic glutamic acid in the TIR domain,which is required for TNL *** findings point to enhanced ETI and systemic resistance by a TNL protein via hyperactivation of the SA ***,RCSP is the first TNL identified to recognize an insect effector.

关键词： chemosensory protein effector effector-triggered immunity salicylic acid TIR-NBS-LRR

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The third dimension of alpine plant leaf traits is related to cold-tolerance

引用

Plant Diversity 2025年第1期47卷 159-165页

作者： Yuan Wang Ji Suonan Kun Liu Yanni Gao Sihao Zhu Qian Liu Ning Zhao state key laboratory of Herbage Improvement and Grassland Agro-ecosystems College of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhouChina college of life sciences Qinghai Normal UniversityXiningChina college of Ecology Lanzhou UniversityLanzhouChina state Environmental Protection key laboratory of Regional Eco-process and Function Assessment Chinese Research Academy of Environmental SciencesBeijingChina state key laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijingChina

Alpine plants possess unique traits to adapt alpine *** leaf trait relationships of alpine plants can be captured by the two trait dimensions of organ size and resource economics is *** hypothesized that,beyond the trait dimensions of leaf size and resource economics,nonstructured carbohydrates(NSC)would reflect a dimension of cold-tolerance in alpine *** test this hypothesis,we measured 12 leaf traits critical to leaf construction and growth in 143 species across 7 sites ranging from alpine steppes to alpine meadows along an environmental gradient on the Tibetan ***,a cold resistance experiment was conducted at one of these sites to estimate the lethal temperature causing 50%frost damage(LT_(50))of 11 alpine *** majority of variations in 12 leaf traits of alpine plants were captured by three trait axes,in which leaf carbon(LCC)and NSC(including leaf starch;LSC and leaf soluble sugars;LSS)were clustered in a new dimension(PC3)beyond leaf size and structure,and resource *** LCC,LSC and LSS all showed negative correlations with mean annual temperature,a significant negative correlation was only found between LSS and LT_(50).It indicated that PC3 was able to reflect the cold-tolerance of alpine plants to some extent,in which LSS was the most critical *** storage and transformation of NSC under stressful conditions could reflect a dimension of long-term metabolic adaptation and cold-tolerance,which is an extension of the resource-utilization strategy beyond construction cost and growth.

关键词： Non-structured carbohydrates Resource economics Stress resistance Trait relationships The lethal temperature causing 50%frost damage(LT50)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：