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检索条件"机构=State Key Lab of New Drug and Pharmaceutical Process"
220 条 记 录,以下是61-70 订阅
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Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects
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Frontiers of Chemical Science and Engineering 2019年 第1期13卷 14-27页
作者: Feng Qi Jie Wu Hao Li Guanghui Ma Beijing Nuokangda pharmaceutical Technology Co. Ltd Beijing 100176 China Department of Mechanical and Aerospace Engineering University of Missouri MO 65211 USA National key laboratory of Biochemical Engineering Key Laboratory of Biopharmaceutical Production and Formulation Engineering PLA Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 China
Poly(D,L-lactic-co-glycolic acid)(PLGA)/poly (lactic acid)(PLA) microspheres/nanoparticles are one of the most successful drug delivery systems (DDS) in lab and clinic. Because of good biocompatibility and biodegradab... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Loss of the vitamin D receptor triggers senescence in chronic myeloid leukemia via DDIT4-mediated DNA damage
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Journal of Molecular Cell Biology 2023年 第10期15卷 65-76页
作者: Yan Xu Wentao Qi Chengzu Zheng Yuan Li Zhiyuan Lu Jianmin Guan Chunhua Lu Baobing Zhao key lab of Chemical Biology(MOE) School of Pharmaceutical SciencesCheeloo College of MedicineShandong UniversityJinan 250012China NMPA key laboratory for Technology Research and Evaluation of drug Products School of Pharmaceutical SciencesCheeloo College of MedicineShandong UniversityJinan 250012China Department of Pharmacology School of Pharmaceutical SciencesCheeloo College of MedicineShandong UniversityJinan 250012China School of pharmaceutical Sciences&Institute of Materia Medica Shandong First Medical University&Shandong Academy of Medical SciencesJinan 250012China Department of Hematology Heze Municipal HospitalHeze 274031China
Chronic myeloid leukemia(CML)is a hematopoietic malignancy driven by the fusion gene BCR::*** resistance to tyrosine kinase inhibitors(TKIs),due to BCR::ABL1 mutations and residual leukemia stem cells(LSCs),remains a ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy
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Acta Pharmaceutica Sinica B 2021年 第7期11卷 2004-2015页
作者: Ling Yu Zhenjie Wang Zhuomao Mo Binhua Zou Yuanyuan Yang Rui Sun Wen Ma Meng Yu Shijun Zhang Zhiqiang Yu Department of Traditional Chinese Medicine the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China The People’s Hospital of Gaozhou Maoming 525200China School of pharmaceutical Sciences Guangdong Provincial Key Laboratory of New Drug ScreeningSouthern Medical UniversityGuangzhou 510515China
Hepatocellular carcinoma(HCC)has been known as the second common leading cancer worldwide,as it responds poorly to both chemotherapy and ***(TP),a diterpenoid triepoxide,is a promising treatment agent for its effectiv... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy
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Chinese Chemical Letters 2020年 第5期31卷 1051-1059页
作者: Qiwen Zhu Madiha Saeed Rundi Song Tao Sun Chen Jiang Haijun Yu state key laboratory of drug Research&1 Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China key laboratory of Smart drug Delivery(Ministry of Education).state key laboratory of Medical Neurobiology.Department of Pharmaceutics School of Pharmacy.Fudan University.Shanghai 201203China University of Chinese Academy of Sciences.Beijing 100049 China
drug delivery systems(DDSs)are of paramount importance to deliver drugs at the intended targets,e.g.,tumor cells or tissue by prolonging blood circulation and optimizing the pharmaceutical ***,the therapeutic efficacy... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Global screening and identification of multiple constituents in Re-Du-Ning injection by UPLC-Q-TOF-MS through the screening of diagnostic ions in MSE mode
Global screening and identification of multiple constituents...
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中国化学会第十届全国天然有机化学学术会议
作者: Hai-Bo Li Yang Yu Zhen-Zhong Wang Jian-Liang Geng Yi Dai Wei Xiao Xin-Sheng Yao Jiangsu Kanion pharmaceutical Co.Ltd. Institute of Traditional Chinese Medicine & Natural Products College of Pharmacy Jinan University state key lab of new-Tech for Chinese Medicine pharmaceutical process Shenyang pharmaceutical University
The broad applications and mechanism explorations of traditional Chinese medicine prescriptions(TCMPs)require a clear understanding of TCMP chemical *** the present study,we describe an efficient and universally appli...
来源: cnki会议 评论
Targeted combination therapy for glioblastoma by co-delivery of doxorubicin,YAP-siRNA and gold nanorods
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Journal of Materials Science & Technology 2021年 第4期63卷 81-90页
作者: Lihuang Li Qiuyan Guo Yanxiu Liu Mindan Lu Jun Yang Yunlong Ge Qiang Zhang Benqiang Sun Xiumin Wang Li Liang-cheng Lei Ren key laboratory of Biomedical Engineering of Fujian Province University/Research Center of Biomedical Engineering of Xiamen Department of BiomaterialsCollege of MaterialsXiamen UniversityXiamen 361005China School of pharmaceutical Sciences Fujian Provincial Key Laboratory of Innovative Drug Target ResearchXiamen UniversityXiamen 361102China Department of Neurosurgery Xiang’an Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361102China Stomatological Hospital of Xiamen Medical College Xiamen 361105China state key lab of Physical Chemistry of Solid Surfaces Xiamen UniversityXiamen 361005China
The combination of brain targeting drug delivery systems and multi-modal intervention pose a promising therapeutic approach for glioblastoma *** this study,we developed an angiopep-2 peptide modified cationic liposome... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Synthesis of 6-(Bromomethyl)-4-methoxy-5,6,7,8-tetrahydropyrido-[3,2-d]pyrimidin-2-ol from 6-Methylpyrimidine-2,4-diol
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Chemical Research in Chinese Universities 2012年 第1期28卷 57-60页
作者: LIU Wei-dong2, DENG Xi-ling2, ZHANG Zhi-li2, WANG Xiao-wei2 and LIU Jun-yi1,2 1. state key laboratory of Natural and Biomimetic drug, 2. Department of Chemical Biology, School of pharmaceutical Sciences, Peking University, Beijing 100191, P. R. China Peking Univ Sch Pharmaceut Sci State Key Lab Nat & Biomimet Drug Beijing 100191 Peoples R China Peking Univ Sch Pharmaceut Sci Dept Biol Chem Beijing 100191 Peoples R China
6-(Bromomethyl)-4-methoxy-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-2-ol(compound 9) was synthe sized from 6-methylpyrimidine-2,4-diol(compound 1) through the crucial steps of 6-methyl alkylating and intramo lecu... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation
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Acta Pharmaceutica Sinica B 2024年 第8期14卷 3543-3560页
作者: Lixin Zhao Yuguang Zhu Hua Tao Xiying Chen Feng Yin Yingyi Zhang Jianfeng Qin Yongyin Huang Bikun Cai Yonghao Lin Jiaxiang Wu Yu Zhang Lu Liang Ao Shen Xi-Yong Yu The Fifth Affiliated Hospital Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target and Clinical PharmacologyNMPA&State Key LaboratorySchool of Pharmaceutical SciencesGuangzhou Medical UniversityGuangzhou 511436China
Pulmonary fibrosis poses a significant health threat with very limited therapeutic options *** this study,we reported the enhanced expression of mesenchymal homobox 1(MEOX1)in pulmonary fibrosis patients,especially in... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Pharmacokinetics Applications of Traditional Chinese Medicines
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World Journal of Traditional Chinese Medicine 2016年 第1期2卷 42-47页
作者: Qiu-Ju Li Ai-Hua Zhang Hui Sun Xi-Jun Wang National TCM key lab of Serum Pharmacochemistry Key Laboratory of Metabolomics and Chinmedomics Department of Pharmaceutical AnalysisHeilongjiang University of Chinese Medicine
Traditional Chinese medicine(TCM) has been widely used in many oriental countries for thousands of years and played an indispensable role in the prevention and treatment of diseases, especially the complicated and chr... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
MicroRNA-34c-5p provokes isoprenaline-induced cardiac hypertrophy by modulating autophagy via targeting ATG4B
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Acta Pharmaceutica Sinica B 2022年 第5期12卷 2374-2390页
作者: Yuhong Zhang Yanqing Ding Min Li Jing Yuan Youhui Yu Xueying Bi Huiqi Hong Jiantao Ye Peiqing Liu Department of Pharmacology and Toxicology School of Pharmaceutical SciencesNational and Local United Engineering Lab of Druggability and New Drugs EvaluationSun Yat-sen UniversityGuangzhou 510006China state key laboratory of Oncology in Southern China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhou 510006China
Pathological cardiac hypertrophy serves as a significant foundation for cardiac dysfunction and heart failure. Recently, growing evidence has revealed that microRNAs(miRNAs) play multiple roles in biological processes... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论