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Cavity-agnostic acoustofluidic manipulations enabled by guided flexural waves on a membrane acoustic waveguide actuator

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Microsystems & Nanoengineering 2024年第2期10卷 153-171页

作者： Philippe Vachon Srinivas Merugu Jaibir Sharma Amit Lal Eldwin J.Ng Yul Koh Joshua E.-Y.Lee Chengkuo Lee Department of Electrical and Computer Engineering National University of SingaporeSingaporeSingapore Institute of Microelectronics Agency for ScienceTechnology and Research(A*STAR)SingaporeSingapore sonicmems laboratory School of Electrical and Computer EngineeringCornell UniversityIthacaNYUSA School of Electrical and Data Engineering University of Technology SydneyUltimoNSWAustralia

This article presents an in-depth exploration of the acoustofluidic capabilities of guided flexural waves(GFWs)generated by a membrane acoustic waveguide actuator(MAWA).By harnessing the potential of GFWs,cavity-agnostic advanced particle manipulation functions are achieved,unlocking new avenues for microfluidic systems and lab-on-a-chip *** localized acoustofluidic effects of GFWs arising from the evanescent nature of the acoustic fields they induce inside a liquid medium are numerically investigated to highlight their unique and promising *** traditional acoustofluidic technologies,the GFWs propagating on the MAWA’s membrane waveguide allow for cavity-agnostic particle manipulation,irrespective of the resonant properties of the fluidic ***,the acoustofluidic functions enabled by the device depend on the flexural mode populating the active region of the membrane *** demonstrations using two types of particles include in-sessile-droplet particle transport,mixing,and spatial separation based on particle diameter,along with streaming-induced counter-flow virtual channel generation in microfluidic PDMS *** experiments emphasize the versatility and potential applications of the MAWA as a microfluidic platform targeted at lab-on-a-chip development and showcase the MAWA’s compatibility with existing microfluidic systems.

关键词： waveguide fluid cavity

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Ultrasonically actuated neural probes for reduced trauma and inflammation in mouse brain

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Microsystems & Nanoengineering 2022年第6期8卷 137-151页

作者： Po-Cheng Chen Catharine G.Young Chris B.Schaffer Amit Lal sonicmems laboratory School of Electrical and Computer EngineeringCornell UniversityIthacaNYUSA Meinig School of Biomedical Engineering Cornell UniversityIthacaNYUSA

Electrical neural recordings measured using direct electrical interfaces with neural tissue suffer from a short lifespan because the signal strength decreases over *** inflammatory response to the inserted microprobe can create insulating tissue over the electrical interfaces,reducing the recorded signal below noise *** of the factors contributing to this inflammatory response is the tissue damage caused during probe ***,we explore the use of ultrasonic actuation of the neural probe during insertion to minimize tissue damage in *** neural microprobes were designed and fabricated with integrated electrical recording sites and piezoelectric *** microprobes were actuated at ultrasonic frequencies using integrated piezoelectric *** microprobes were inserted into mouse brains under a glass window over the brain surface to image the tissue surrounding the probe using two-photon *** mechanical force required to penetrate the tissue was reduced by a factor of 2–3 when the microprobe was driven at ultrasonic *** histology at the probe insertion site showed a reduced area of damage and decreased microglia counts with increasing ultrasonic actuation of the *** imaging of the microprobe over weeks demonstrated stabilization of the inflammatory *** of electrical signals from neurons over time suggests that microprobes inserted using ultrasound have a higher signal-tonoise ratio over an extended time period.

关键词： microprobe insertion electrical

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微型核电池的研究

微型核电池的研究

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第十四届全国核电子学与核探测技术学术年会

作者：郭航 Amit Lal James Blanchard 厦门大学萨本栋微机电研究中心 sonicmems laboratory Cornell University Ithaca Department of Engineering Physics University of Wisconsin-Madison Madison

目前国内外正在研究的各种微型能源产生技术中,利用从放射性同位素中发射出的带电粒子的动能转换成电能的微型核电池在许多领域具有应用前景。本文作者评述了以往开发的应用于微机电系统和纳米器件的微型同位素电池,包括Beta型放射性同... 详细信息

目前国内外正在研究的各种微型能源产生技术中,利用从放射性同位素中发射出的带电粒子的动能转换成电能的微型核电池在许多领域具有应用前景。本文作者评述了以往开发的应用于微机电系统和纳米器件的微型同位素电池,包括Beta型放射性同位素微型核电池与直接电流收集型同位素核电池两种类型。这两种类型的核电池都使用镍-63放射性同位素;此外,本文还给出了使用钷-147同位素作为Beta型放射性同位素微型核电池的最新结果。

关键词：微型核电池微型Beta放射性同位素电池镍-63 钷-147

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