检索结果-南通市图书馆

Estimation of Physiologic Ability and Surgical Stress scoring system for predicting complications following abdominal surgery: A metaanalysis spanning 2004 to 2022

引用

World Journal of Gastrointestinal Surgery 2024年第1期16卷 215-227页

作者： Tian-Shu Pang Li-Ping Cao Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina

BACKGROUND Postoperative complications remain a paramount concern for surgeons and healthcare *** To present a comprehensive analysis of the Estimation of Physiologic Ability and Surgical Stress(E-PASS)scoring system’s efficacy in predicting postoperative complications following abdominal *** A systematic search of published studies was conducted,yielding 17 studies with pertinent *** such as preoperative risk score(PRS),surgical stress score(SSS),comprehensive risk score(CRS),postoperative complications,post-operative mortality,and other clinical data were collected for *** plots were employed for continuous and binary variables,withχ2 tests assessing heterogeneity(P value).RESULTS Patients experiencing complications after abdominal surgery exhibited significantly higher E-PASS scores compared to those without complications[mean difference and 95%confidence interval(CI)of PRS:0.10(0.05-0.15);SSS:0.04(0.001-0.08);CRS:0.19(0.07-0.31)].Following the exclusion of low-quality studies,results remained valid with no discernible *** analysis indicated that variations in sample size and age may contribute to hetero-geneity in CRS *** variable meta-analysis demonstrated a correlation between high CRS and increased postoperative complication rates[odds ratio(OR)(95%CI):3.01(1.83-4.95)],with a significant association observed between high CRS and postoperative mortality[OR(95%CI):15.49(3.75-64.01)].CONCLUSION In summary,postoperative complications in abdominal surgery,as assessed by the E-PASS scoring system,are consistently linked to elevated PRS,SSS,and CRS *** CRS scores emerge as risk factors for heightened morbidity and *** study establishes the accuracy of the E-PASS scoring system in predicting postoperative morbidity and mortality in abdominal surgery,underscoring its potential for widespread adoption in effective risk assessment.

关键词： Estimation of Physiologic Ability and Surgical Stress scoring system Preoperative risk score Surgical stress score Comprehensive risk score Complications

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The clinical application and advancement of robot-assisted McKeown minimally invasive esophagectomy for esophageal cancer

引用

Laparoscopic, Endoscopic and Robotic Surgery 2024年第1期7卷 6-10页

作者： Raojun Luo Yiming Li Xiumin Han Yunzheng Wang Zhengfu He Peijian Yan Ziyi Zhu Department of Thoracic Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Department of Operating Room Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Robotic surgery systems,as emerging minimally invasive approaches,have been increasingly applied for the treatment of esophageal cancer because they provide a high-definition three-dimensional surgical view and mechanical rotating arms that surpass the limitations of human hands,greatly enhancing the accuracy and flexibility of surgical ***-assisted McKeown esophagectomy(RAME),a common type of robotic esophagectomy,has been gradually implemented with the aim of reducing postoperative complications,improving postoperative recovery and achieving better long-term *** centers worldwide have reported and summarized their experiences with the RAME,and some have also discussed and analyzed its perioperative effects and survival prognosis compared with those of video-assisted minimally invasive *** to traditional surgery,the RAME has significant advantages in terms of lymph node dissection although there seems to be no difference in overall survival or disease-free *** the continuous advancement of technology and the development of robotic technology,further development and innovation are expected in the RAME *** review elaborates on the prospects of the application and advancement of the RAME to provide a useful reference for clinical practice.

关键词： Esophageal cancer Minimally invasive esophagectomy Robot-assisted McKeown esophagectomy Lymph node dissection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recentprogress in thebiomedical application of PEDOT:PSS hydrogels

引用

Chinese Chemical Letters 2024年第10期35卷 13-27页

作者： Binhan Zhao Zheng Li Lan Zheng Zhichao Ye Yuyang Yuan Shanshan Zhang Bo Liang Tianyu Li National Engineering Research Center of Innovation and Application of Minimally Invasive Instruments Sir Run Run Shaw HospitalSchool of MedicineZhejiangUniversityHangzhou 310028China Department of Translational Medicine Clinical Research Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310028China Biosensor National Special Laboratory College of Biomedical Engineering and Instrument ScienceZhejiang UniversityHangzhou 310028China School of Medicine Zhejiang UniversityHangzhou 310028China

Bioelectronics have gained substantial research attention owing to their potential applications in health monitoring and diagnose,and greatly promoted the development of ***,poly(3,4-ethylenedioxythiophene):polystyrene sulfonate(PEDOT:PSS)hydrogels have arose as a promising candi-date for the next-generation bioelectronic interface due to its high-conductivity,versatility,flexibility and *** this review,we highlight the recent advances of PEDOT:PSS hydrogels,including the gelation methods and modification strategies,and summarize their wide applications in different type of sensors and tissue engineering in *** expect that this work will provide valuable information regarding the functionalizations and applications of PEDOT:PSS hydrogels.

关键词： Conductingpolymer PEDOT:PSS hydrogels Conjugatedpolymer Gelation methods Biomedicalapplication

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Construction and validation of a risk-prediction model for anastomotic leakage after radical gastrectomy: A cohort study in China

引用

Laparoscopic, Endoscopic and Robotic Surgery 2024年第1期7卷 34-43页

作者： Jinrui Wang Xiaolin Liu Hongying Pan Yihong Xu Mizhi Wu Xiuping Li Yang Gao Meijuan Wang Mengya Yan Nursing Department Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Department of General Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China School of Nursing Zhejiang Chinese Medical UniversityHangzhou 310053China

Objectives:Anastomotic leakage(AL)stands out as a prevalent and severe complication following gastric cancer *** frequently precipitates additional serious complications,significantly influencing the overall survival time of *** study aims to enhance the risk-assessment strategy for AL following gastrectomy for gastric ***:This study included a derivation cohort and validation *** derivation cohort included patients who underwent radical gastrectomy at sir run run shaw hospital,Zhejiang University School of Medicine,from January 1,2015 to December 31,*** evidence-based predictor questionnaire was crafted through extensive literature review and panel *** on the questionnaire,inpatient data were collected to form a model-derivation *** cohort underwent both univariate and multivariate analyses to identify factors associated with AL events,and a logistic regression model with stepwise regression was developed.A 5-fold cross-validation ensured model *** validation cohort included patients from August 1,2021 to December 31,2021 at the same *** the same imputation method,we organized the validation-queue *** then employed the risk-prediction model constructed in the earlier phase of the study to predict the risk of AL in the subjects included in the validation *** compared the predictions with the actual occurrence,and evaluated the external validation performance of the model using model-evaluation indicators such as the area under the receiver operating characteristic curve(AUROC),Brier score,and calibration ***:The derivation cohort included 1377 patients,and the validation cohort included 131 *** independent predictors of AL after radical gastrectomy included age65 y,preoperative albumin<35 g/L,resection extent,operative time240 min,and intraoperative blood loss90 *** predictive model exhibited a solid AUROC of 0.750(95%CI:0.694e0.806;p<0.001)with a Br

关键词： Stomach neoplasms Anastomotic leak Risk factors Prediction model Risk assessment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interlayer repair with porcine small intestinal submucosa versus internal repair with tragus cartilage in endoscopic tympanoplasty

引用

Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 79-86页

作者： Lina Zhao Wenya Li Lei Zhang Department of Otolaryngology Head and Neck Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Objective Endoscopic tympanoplasty includes various surgical methods,such as internal repair,interlayer repair,and external *** technique requires autologous materials,allografts,and xenografts,which are used to repair tympanic membrane(TM)*** obtain good results,appropriate surgical methods and repair materials should be *** study aims to assess the efficacy of repairing refractory TM perforations in the porcine small intestinal submucosa(SIS)during transcanal endoscopic type I *** A retrospective chart review was performed on patients who underwent TM perforation repair with porcine SIS and tragus cartilage between January 2022 and September 2022 at sir run run shaw hospital,Zhejiang University School of *** size,tympanic status,pre-and postoperative symptoms,follow-up data,wound healing rates,and hearing improvement were *** Of the 115 patients included in the study,56 underwent interlayer repair with porcine SIS of the TM,and 59 patients underwent internal repair with tragus *** significant difference was found between the two groups at baseline in terms of age,sex,disease course,perforation side,tympanic status,underlying disease,or preoperative *** total postoperative effective rate of interlayer implantation with porcine SIS was 91.07%(51 patients),and that of internal implantation with tragus cartilage was 88.14%(52 patients).No significant difference was found in terms of the graft success rate between the two surgical methods(p=0.887).Postoperative pure tone auditory(PTA)and air-bone gap(ABG)density significantly increased in both groups compared with before surgery(p0.05).Compared to those in the internal implantation group,the patients in the interlayer group had a shorter operation duration(51.36±6.76 min vs.59.71±7.45 min,t=6.2

关键词： Porcine small intestinal submucosa Tragus cartilage Interlayer implantation Internal implantation Tympanic membrane Endoscopic tympanoplasty

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Micro-power negative pressure wound technique reduces risk of incision infection following loop ileostomy closure

引用

World Journal of Gastrointestinal Surgery 2024年第1期16卷 186-195页

作者： Deng-Yong Xu Bing-Jun Bai Lina Shan Hui-Yan Wei Deng-Feng Lin Ya Wang Da Wang Department of Colorectal Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Department of Wound&Ostomy Care Clinic Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Department of hospital Infection Control Zhejiang Cancer HospitalHangzhou 310005Zhejiang ProvinceChina

BACKGROUND Prophylactic loop ileostomy is an effective way to reduce the clinical severity of anastomotic leakage following radical resection of rectal *** surgical site infection(SSI)is a common complication after ileostomy *** To evaluate the efficacy and safety of the micro-power negative pressure wound technique(MPNPWT)in preventing incisional *** This was a prospective,randomized controlled clinical trial conducted at a single center.A total of 101 consecutive patients who underwent ileostomy closure after rectal cancer surgery with a prophylactic ileostomy were enrolled from January 2019 to December *** were randomly allocated into an MPNPWT group and a control *** MPNPWT group underwent intermittent suturing of the surgical incision with 2-0 Prolene and was covered with a micro-power negative pressure *** surgical outcomes were compared between the MPNPWT(n=50)and control(n=51)*** factors for incisional SSI were identified using logistic *** There were no differences in baseline characteristics between the MPNPWT(n=50)and control groups(n=51).The incisional SSI rate was significantly higher in the control group than in the MPNPWT group(15.7%vs 2.0%,P=0.031).However,MPNPWT did not affect other surgical outcomes,including intra-abdominal complications,operative time,and blood *** hospital stay length and hospitalization costs did not differ significantly between the two groups(P=0.069 and 0.843,respectively).None of the patients experienced adverse effects of MPNPWT,including skin allergy,dermatitis,and *** also helped heal the infected *** study indicated that MPNPWT was an independent protective factor[odds ratio(OR)=0.005,P=0.025)]and diabetes was a risk factor(OR=26.575,P=0.029)for incisional *** MPNPWT is an effective and safe way to prevent incisional SSI after loop ileostomy closure.

关键词： Micro-power negative pressure technique Ileostomy closure Incisional surgical site infection Infection prevention Postoperative incision

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Therapeutic advances in atrial fibrillation based on animal models

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第2期25卷 135-152页

作者： Qian GONG Xuan LE Pengcheng YU Lenan ZHUANG Institute of Genetics and Reproduction College of Animal SciencesZhejiang UniversityHangzhou310058China Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province Department of CardiologySir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou310016China

Atrial fibrillation(AF)is the most prevalent sustained cardiac arrhythmia among humans,with its incidence increasing significantly with *** the high frequency of AF in clinical practice,its etiology and management remain *** develop effective treatment strategies,it is imperative to comprehend the underlying mechanisms of AF;therefore,the establishment of animal models of AF is vital to explore its *** spontaneous AF is rare in most animal species,several large animal models,particularly those of pigs,dogs,and horses,have proven as invaluable in recent years in advancing our knowledge of AF pathogenesis and developing novel therapeutic *** review aims to provide a comprehensive discussion of various animal models of AF,with an emphasis on the unique features of each model and its utility in AF research and *** data summarized in this review provide valuable insights into the mechanisms of AF and can be used to evaluate the efficacy and safety of novel therapeutic interventions.

关键词： Atrial fibrillation Animal model Therapeutic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

GABAergic Interneuron Cell Therapy for Drug-Resistant Epilepsy

引用

Neuroscience Bulletin 2024年第5期40卷 680-682页

作者： Junzi Chen Zhongxia Li Yi Wang Liying Chen Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province First Affiliated Hospital and School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhou310053China Department of Pharmacy Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou310016China

Epilepsy,one of the most common central nervous system disorders,affects about 70 million people of all ages worldwide[1].It is characterized by hyperactive neuronal networks,resulting from imbalanced excitatory and inhibitory *** the development of multiple next-generation anti-seizure medicines,one-third of epilepsy patients are still drug-resistant[2].

关键词： epilepsy Therapy seizure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multifunctional RGD coated a single-atom iron nanozyme:A highly selective approach to inducing ferroptosis and enhancing immunotherapy for pancreatic cancer

引用

Nano Research 2024年第6期17卷 5469-5478页

作者： Haoqi Pan Xu Chen Mingming Xiao He Xu Jiansheng Guo Zhiyi Lu Dong Cen Xianjun Yu Si Shi Department of Pancreatic Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Shanghai Pancreatic Cancer Institute Shanghai 200032China Pancreatic Cancer Institute Fudan UniversityShanghai 200032China Key Laboratory of Advanced Fuel Cells and Electrolyzers Technology of Zhejiang Province Qianwan Institute of CNITECHNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Department of Pathology of sir run run shaw hospital Zhejiang University School of MedicineHangzhou 310016China Key Laboratory of Laparoscopic Technology of Zhejiang Province Department of General SurgerySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Nanozyme is a new promising approach to cancer therapy for its ability to induce ferroptosis by activating H_(2)O_(2)via a traditional radical pathway and enhance cancer ***,short half-life period of hydroxyl radical(·OH)results in unsatisfied ***,we synthesized a single-atom iron nanozyme(Fe-SAzyme),which can activate H_(2)O_(2)via a non-radical pathway to generate Fe-based reactive oxygen species(ROS)(O=FeO_(3)=O)for promoting the ferroptosis of pancreatic cancer *** Fe-SAzyme could be specifically phagocytosed by pancreatic cancer cells,increasing ROS levels and inhibiting glutathione(GSH)synthesis,which activates *** magnetic resonance imaging(MRI)showed decreased T2 signal after intravenous injection of RGD@Fe-AC(AC=activated carbon).Moreover,RGD@Fe-AC promoted dendritic cell(DC)maturation,overcame Treg-mediated immunosuppression,activated T cells to trigger adaptive immune responses,and enhanced the efficacy ofα-PD-L1 *** research demonstrated that RGD@Fe-AC provided a straightforward,easily implemented,and selective approach for pancreatic cancer treatment and immunotherapy.

关键词： single-atom iron nanozyme pancreatic cancer immunotherapy ferroptosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Review of Baduanjin and resistance exercise for the mental health of patients with hematologic malignancies

引用

World Journal of Psychiatry 2024年第8期14卷 1165-1173页

作者： Ya-Zhou Shen Feng Chen Jia-Wen Yu Yan Zhang Ling-Xiang Lu Yong-Li Huo Si-Ting Chu Bing Cao Lei-Wen Tang Department of Nursing Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Nursing The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

Patients with hematological tumors experience physical and psychological stress,and negative psychological ***,an emerging psychological rehabil-itation method combined with resistance exercise,has received widespread *** study reviews the current status of the application of Baduanjin combined with resistance exercise in improving the negative psychological state of patients with hematological tumors and discusses its problems and *** a literature review and comprehensive analysis,the application of Baduanjin and resistance exercise in the psychological rehabilitation of patients with hematological tumors was identified and *** results showed that Baduanjin with resistance exercise had a positive effect on improving negative psychological states of patients with hematological tumors,which can alleviate anxiety,depression,and other adverse emotions,and improve quality of ***,there is a lack of unified and standardized exercise intervention programs for practical application,and patient participation and compliance must be *** combined with resistance exercise can potentially improve the negative psychological status of patients with hematological tumors;however,it is still necessary to further standardize and improve the exercise program improving patient participation and *** studies should strengthen theoretical exploration and empirical research,providing more effective psychological rehabilitation strategies for patients with hematological tumors.

关键词： Hematological tumors Baduanjin Resistance exercise Negative psychological state Psychological rehabilitation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：