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Prevalence and Years of Life Lost due to Disability from Dental Caries among Children and Adolescents in Western China,1990-2015

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Biomedical and Environmental Sciences 2017年第10期30卷 701-707页

作者： WANG Zhuo DENG Ying LIU Shi Wei HE Jun JI Kui ZENG Xin Ying YANG Shu Juan XU Xin Yin LUO Yu ZHOU Mai Geng ZHANG Jian Xin West China School of Public Health Sichuan University sichuan Provincial Center for disease control and prevention Center for Chronic and Noncommunicable Disease Control and Prevention National Center for Chronic and Noncommunicable disease control and prevention Chinese Center for Disease Control and Prevention Department of Obstetrics and Gynecology West China Second University HospitalSichuan University

Objective To analyze the prevalence and years lived with disability （YLD） from dental caries among children and adolescents and the time trends over the past two decades in sichuan province, the largest province in west China. Methods Based on the Global Burden of disease Study 2015 （GBD2015）, which systematically assessed the epidemiological characteristics of major diseases and their transitions by country and region from 1990 to 2015, we extracted the estimated results for China. We then used the Bayesian meta-regression method to estimate the sex- and age-specific prevalences and YLDs from dental caries among children and adolescents under 15 years old in sichuan province and compared them with global and national indicators for the same period. Results In 2015, there were almost 6 million cases of dental caries in children and adolescents （aged 〈 15 years） in sichuan province, accounting for 6% of the total cases in China. For children under 5 years, the prevalence of deciduous caries was 55.9%, and the YLDs value was 10.8 per 100,000, while it was 24.3% and 5.1 per 100,000 respectively among 5- to 14-year-olds; for those aged 5 to 14 years, the prevalence of permanent caries was 21.5%, and the YLDs value was 11.5 per 100,000. From 1990 to 2015, the prevalence of dental caries for children under 5 years increased substantially, by 16.2%, and the YLDs increased by 8.7%. Among those aged 5 to 14 years, the prevalence increased and the YLDs decreased. Conclusion Dental caries remains a huge health burden in Western China. In contrast to the global and national data, the trend has increased rapidly over the past 25 years in this region. This work provides suggestions for the prevention and control for oral health in China with the policy of two-child.

关键词： Children and adolescents Dental caries YLD disease burden

Five Independent Cases of Human Infection with Avian Influenza H5N6—sichuan Province,China,2021

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China CDC weekly 2021年第36期3卷 751-756,I0001页

作者： Chongkun Xiao Jianan Xu Yu Lan Zhongping Huang Lijun Zhou Yaxin Guo Xiyan Li Lei Yang George F.Gao Dayan Wang William J.Liu Xingyu Zhou Huiping Yang sichuan Center for disease control and prevention ChengduSichuanChina NHC Key Laboratory of Biosafety National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina.

Summary What is known about this topic?The emerging H5Ny lineages of the avian influenza virus(AIV)with genomic reassortments have posed a continuous threat to animals and human *** the first case of avian influenza A... 详细信息

关键词： H5N6 Independent Human

An Investigation on the Molecular Characteristics and Intracellular Growth Ability among Environmental and Clinical Isolates of Legionella pneumophila in sichuan Province, China

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Biomedical and Environmental Sciences 2019年第7期32卷 520-530页

作者： ZENG Lin Zi LIAO Hong Yu LUO Long Ze HE Shu Sen QIN Tian ZHOU Hai Jian LI Hong Xia CHEN Da Li CHEN Jian Ping Department of Parasitology West China School of Basic Medical Sciences & Forensic Medicine Sichuan University Chengdu 610041 Sichuan China sichuan Center for disease control and prevention Chengdu 610041 Sichuan China State Key Laboratory for Infectious disease prevention and control National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China Chengdu first people's Hospital Chengdu 610041 Sichuan China

Objective To investigate the molecular characteristics and intracellular growth ability of Legionella pneumophila(L. pneumophila) strains from 1989 to 2016 in sichuan Province, China. Methods Seventy-nine isolates of L. pneumophila were collected from environmental and clinical sources, including cooling towers, hot springs, bath water, fountains, and patients, and identified with 16 S rRNA gene analysis and serum agglutination assay. The isolates were then typed by Sequence-Based Typing(SBT), and Genotyping of forty-two LP1 strains were analyzed by means of multiple-locus VNTR analysis with 8 loci(MLVA-8). All strains were further analyzed for two virulence genes: Legionella vir homologue(lvh) and repeats in structural toxin(rtx A). The intracellular growth ability of 33 selected isolates was determined by examining their interaction with J774 cells. Results All isolates were identified to L. pneumophila including 11 serogroups, among which the main serogroup were LP1, accounting for 54.43%. Thirty-three different sequence types(STs) from five main clonal groups and five singletons were identified, along with 8 different MLVA patterns. Both the lvh and rtx A loci were found in all 79 strains. Thirty isolates showed high intracellular growth ability in J774 cells. Conclusion L. pneumophila is a potential threat to public health, and effective control and prevention strategies are urgently needed.

关键词： Molecular characteristics Intracellular growth ability Environments Clinical L.pneumophila sichuan

Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus—sichuan Province,China,2019

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China CDC weekly 2020年第11期2卷 172-175页

作者： Jiushun Zhou Ning Wen Yong Zhang Qi Qi Chunxiang Fan Dongmei Yan Xiaoping Zhu Lixin Hao Shuangli Zhu Yu Liu Xiaozhen Ma Chao Ma Lei Nan Yong Chen Qianli Ma Cheng Wang Kun Deng Lei Cao Ge Shao Xianxiang Ding Hong Yang Zhijie An Lance ERodewald Aiqiang Xu Huaqing Wang Zijian Feng Zundong Yin Xianping Wu Wenbo Xu sichuan Provincial Center for disease control and prevention ChengduSichuanChina National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina National Institute for Viral disease control and prevention Chinese Center for Disease Control and PreventionBeijingChina Liangshan Yi Autonomous Prefectural Center for disease control and prevention XichangSichuanChina Leibo county Center for disease control and prevention LeiboLiangshanSichuanChina Chinese Field Epidemiology Training Program Chinese Center for disease control and prevention BeijingChina Shandong Provincial Center for disease control and prevention JinanShandongChina

What is already known about this topic?After the type 2 strain of the live,attenuated poliovirus vaccine was withdrawn globally in 2016,any identification of a type 2 poliovirus is a Public Health Emergency of International Concern.A vaccinederived type 2 poliovirus(VDPV2)was identified in sichuan,prompting an urgent,comprehensive investigation and *** is added by this report?Type 2 monovalent,live,attenuated oral poliovirus vaccine(mOPV2)is being used to respond to the numerous VDPV2 outbreaks seen around the *** contrast,the response in sichuan used Sabin strain inactivated poliovirus(sIPV)to stop circulation of the *** the 6 months following the vaccination response,there have been no VDPV2s detected in sichuan,despite extensive *** are the implications for public health practices?Further search for the VDPV2 must continue in order to determine whether transmission has been *** ongoing investigation and response to the sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks.

关键词： prompt globally Type

Coverage of 13-Valent Pneumococcal Conjugate Vaccine Among Children 0–15 Months of Age—9 Provinces,China,2019–2021

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China CDC weekly 2023年第17期5卷 379-384页

作者： Lijun Liu Zhaonan Zhang Xixi Zhang Changsha Xu Yifan Song Li Li Jiakai Ye Zhiguo Wang Hui Liang Weiyan Zhang Ling Lin Ning Li Shujun Zhang Qianli Ma Wen Du Yongzhuo Jiao Lingsheng Cao Qi Qi Lei Cao Wenzhou Yu sichuan Center for disease control and prevention Chengdu CitySichuan ProvinceChina National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina Suqian Center for disease control and prevention Suqian CityJiangsu ProvinceChina Jiangsu Center for disease control and prevention Nanjing CityJiangsu ProvinceChina Zhejiang Center for disease control and prevention Hangzhou CityZhejiang ProvinceChina Shandong Center for disease control and prevention Jinan CityShandong ProvinceChina Anhui Center for disease control and prevention Hefei CityAnhui ProvinceChina Hubei Center for disease control and prevention Wuhan CityHubei ProvinceChina Hunan Center for disease control and prevention Changsha CityHunan ProvinceChina Guizhou Center for disease control and prevention Guiyang CityGuizhou ProvinceChina Gansu Center for disease control and prevention Lanzhou CityGansu ProvinceChina

Summary What is already known on this topic?Limited data exist regarding the coverage of the 13-valent pneumococcal conjugate vaccine(PCV13)in China.A lack of official statistics,coupled with an insufficient body of published literature,hinders the accurate depiction of the current *** is added by this report?This study investigated the utilization of PCV13 and estimated its coverage in nine provinces across eastern,central,and western China between 2019 and *** an annual increase in PCV13 usage during this period,the overall coverage remained suboptimal.

关键词： spite coverage hinder

Coverage of the Combined DTaP-IPV/Hib Vaccine Among Children Aged 2-18 Months—9 PLADs,China,2019-2021

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China CDC weekly 2024年第19期6卷 418-423,I0001页

作者： Li Li Hui Liang Yifan Song Zhaonan Zhang Jing An Ning Li Huifeng Sun Ying Bao Leijin Mao Lin Ding Jie Yan Zhiguo Wang Lei Cao Jiakai Ye Wenzhou Yu National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases BeijingChina National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina Zhejiang Center for disease control and prevention Hangzhou CityZhejiang ProvinceChina Gansu Center for disease control and prevention Lanzhou CityGansu ProvinceChina Hubei Center for disease control and prevention Wuhan CityHubei ProvinceChina Shandong Center for disease control and prevention Jinan CityShandong ProvinceChina sichuan Center for disease control and prevention Chengdu CitySichuan ProvinceChina Anhui Center for disease control and prevention Hefei CityAnhui ProvinceChina Guizhou Center for disease control and prevention Guiyang CityGuizhou ProvinceChina Hunan Center for disease control and prevention Changsha CityHunan ProvinceChina Jiangsu Center for disease control and prevention Nanjing CityJiangsu ProvinceChina

Summary What is already known on this topic?In China,there is limited data available on the use and coverage of the non-program,combined diphtheria,tetanus toxoid,acellular pertussis adsorbed,inactivated poliovirus and haemophilus influenzae type b(DTaPIPV/Hib)pentavalent vaccine,and its role as a substitute for the separately administered standalone program vaccines.

关键词： vaccine Hib DTaP

The First Case of COVID-19 by an A.27 Lineage Variant Detected in a Returning Employee—sichuan Province,China,January 7,2021

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China CDC weekly 2021年第34期3卷 725-727页

作者： Li Liu Tao Luo Gaopeng Lei Yuliang Feng Xiang Zhao Huiping Yang Jianan Xu Ming Pan Linlin Zhou sichuan Provincial Center for disease control and prevention ChengduSichuanChina West China School of Basic Medical Sciences&Forensic Medicine Sichuan UniversityChengduSichuanChina National Institute for Viral disease control and prevention Chinese Center for Disease Control and PreventionBeijingChina

On January 7,2021,a 32-year-old returning employee arrived in Chengdu from Algeria via airplane and tested positive for coronavirus disease 2019(COVID-19)by nucleic acid *** was transferred to the designated hospital for further diagnosis and *** patient was diagnosed as a mild COVID-19 case on January *** medical treatment,this patient recovered and left the hospital on February 18.

关键词： treatment transferred COV

Emergence of a SARS-CoV-2 Omicron Subvariant BA.2.2 with a 454-Nucleotide Genomic Deletion-sichuan Province,China,May 10,2022

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China CDC weekly 2022年第40期4卷 904-906页

作者： Yuliang Feng Xiang Zhao Tao Luo Zhixiao Chen Huiping Yang Na Chen Xiaozhen Ma Mingyuan Li Weihua Zhang Sikai Jia Xun Yuan Ming Pan Linlin Zhou sichuan Center for disease control and prevention Chengdu CitySichuan ProvinceChina National Institute for Viral disease control and prevention Chinese Center for Disease Control and PreventionBeijingChina West China School of Basic Medical Sciences&Forensic Medicine Sichuan UniversityChengdu CitySichuan ProvinceChina College of Computer Science Sichuan UniversityChengdu CitySichuan ProvinceChina Guang’an Center for disease control and prevention Guang’an CitySichuan ProvinceChina

On May 9,2022,3 local residents in Guang’an City,sichuan Province,tested positive for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and were diagnosed as asymptomatic infections with coronavirus disease 2019(COVID-19)in a local outbreak,and as of May 14,a total of 20 confirmed cases and 398 asymptomatic infections were *** genome sequencing was performed directly on the nasal and throat swab specimens from the initial three asymptomatic infected individuals using the Illumina MiSeq platform(Illumina,San Diego,CA,USA).The complete genome sequences of 3 SARSCoV-2 strains,named SC1215,SC1216,and SC1217,were *** sequence of SC1217 has been deposited in the GISAID database(under the accession number EPI_ISL_12725020).

关键词： residents Whole fir

Prevalence,Incidence,and Characteristics of Tuberculosis Among Known Diabetes Patients—A Prospective Cohort Study in 10 Sites,2013–2015

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China CDC weekly 2022年第3期4卷 41-46页

作者： Jun Cheng Yanling Yu Qiongjin Ma Zhijian Wang Qingrong Zhou Guolong Zhang Shuangyi Hou Lin Zhou Feiying Liu Lan Xia Lin Xu Canyou Zhang Yinyin Xia Hui Chen Hui Zhang Lixia Wang National Center for Tuberculosis control and prevention China CDCBeijingChina Heilongjiang Provincial Center for disease control and prevention HarbinHeilongjiangChina Minhang District Center for disease control and prevention ShanghaiChina Center for disease control and prevention of Danyang County DanyangJiangsuChina Center for disease control and prevention of Jiangshan city JiangshanZhejiangChina Henan Provincial Center for disease control and prevention ZhengzhouHenanChina Hubei Provincial Center for disease control and prevention WuhanHubeiChina Center for Tuberculosis control of Guangdong Province GuangzhouGuangdongChina Guangxi Center for disease prevention and control NanningGuangxi Zhuang Autonomous RegionChina sichuan Provincial Center for disease control and prevention ChengduSichuanChina Yunnan Provincial Center for disease control and prevention KunmingYunnanChina

Summary What is already known about this topic?The association of diabetes mellitus(DM)with both increased risk of tuberculosis(TB)and unfavorable treatment outcomes has been identified by many studies(1).However,epidemic data for TB cases in DM patients is absent in *** is added by this report?This current population-based prospective cohort study,conducted in ten counties located in eastern,central,and western China during 2013–2015,revealed a high prevalence and incidence of TB in known DM *** TB cases were captured by active case-finding and a much higher presence of being asymptomatic among TB/DM patients was *** are the implications for public health practice?Active case-finding should be carried out in DM patients and populations at high risk for developing TB.A TB symptom screening-based case-finding strategy is not enough;chest radiography check should be done once a year for these patients.

关键词： finding Diabetes Patients