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Chinese Physics B 2015年第10期24卷 604-611页

作者： Gopi Krishna Saramekala Sarvesh Dubey Pramod Kumar Tiwari Department of Electronics and Communication Engineering National Institute of Technology shri ramswaroop memorial university

In this paper, a surface potential based threshold voltage model of fully-depleted（FD） recessed-source/drain（Re-S/D）silicon-on-insulator（SOI） metal-oxide semiconductor field-effect transistor（MOSFET） is presented while considering the effects of high-k gate-dielectric material induced fringing-field. The two-dimensional（2D） Poisson＇s equation is solved in a channel region in order to obtain the surface potential under the assumption of the parabolic potential profile in the transverse direction of the channel with appropriate boundary conditions. The accuracy of the model is verified by comparing the model＇s results with the 2D simulation results from ATLAS over a wide range of channel lengths and other parameters,including the dielectric constant of gate-dielectric material.

关键词： recessed-source/drain (Re-S/D) high-k gate-material fringing field and SCEs

Prevention and treatment of hypoxia-induced colorectal cancer damage in albino Wister rats

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Life Research 2024年第1期7卷 16-23页

作者： Ishrat Jahan Manju Pandey Shalini Pal Bushra Jabi Mohd Yaqub Khan Gaurav Kaithwas Department of Pharmaceutical Sciences Babasaheb Bhimrao Ambedkar UniversityLucknow 226025 India Institute of Pharmacy Shri Ramswaroop Memorial UniversityBarabanki 225003India School of Pharmaceutical Education&Research Jamia HamdardNew Delhi 110062India Institute of Pharmacy Azad Institute of Pharmacy and ResearchLucknow 226008India

Background:In the early metastasis of colon cancer,cancer cells detach,migrate,and infiltrate surrounding tissues,including lymph vessels and blood *** heterogeneity arises from both tumor cells and distinct *** of blood vessels,creates hypoxic regions within the tumors,fostering cancer stem cell-like properties due to reduced oxygen and nutrient *** hypoxia,tumor cells shift to a glycolytic pathway,producing more lactic acid that acidifies the microenvironment and leads to unstable heart rate variability(HRV)factors,weight disparity,and a higher incidence of aberrant crypt foci(ACF).These hypoxic-induced parameters promote cancer cell invasion,increase radiation resistance,and facilitate cancer cell ***:In this study,we induced hypoxia-preneoplastic colon damage in albino Wister rats by administrating 1,2-dimethyl hydrazine(DMH).After successfully creating a hypoxic environment in albino Wister rats,resulting in preneoplastic colon damage,we randomly allocated Wistar albino rats into seven groups,each containing 8 animals,and conducted a 6-week *** 1-Normal control(administered 1 mM EDTA+saline,2 ml/kg/day,p.o.);group 2-Toxic control(administered DMH,30 mg/kg/week,s.c.);group 3-Standard treatment(DMH,30 mg/kg/week,*** 6 weeks),followed by 5-fluorouracil and Leucovorin(25 mg/kg each on 1^(st),3^(rd),7^(th),and 10^(th) days,*** 6 weeks administration of DMH);group 4-Low dose of P1(DMH,30 mg/kg/week,s.c.+P1,2 mg/kg,i.v.,weekly for 3 weeks);group 5-High dose P1(DMH,30 mg/kg/week,s.c.+P1,4 mg/kg,i.v.,weekly for 3 weeks),group 6-Low dose of P2(DMH,30 mg/kg/week,s.c.,+P2,2 mg/kg,i.v.,weekly for 3 weeks),group 7-High dose of P2(DMH,30 mg/kg/week,s.c.,+P2,4 mg/kg,*** for 3 weeks).Results:DMH-treated rats exhibited alterations in HRV factors,weight disparity,elevated gastric pH,increased total acidity,a higher incidence of ACF,and changes in antioxidant markers(TBARs,SOD,catalase,GSH).Bri

关键词： colon cancer 1,2,4-triazine derivatives oxidative stress hypoxia-induced colon carcinogenesis

Studying the efficacy of isolation as a control strategy and elimination of tuberculosis in India:A mathematical model

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Infectious Disease Modelling 2023年第2期8卷 458-470页

作者： Archana Singh Bhadauria Hom Nath Dhungana Vinay Verma Stephen Woodcock Tapan Rai Department of Mathematics and Statistics Deen Dayal Upadhyaya Gorakhpur UniversityIndia School of Mathematical and Physical Sciences University of Technology SydneyAustralia Faculty of Mathematical and Statistical Sciences Institute of Natural Sciences and HumanitiesShri Ramswaroop Memorial UniversityUttar PradeshIndia

India has the highest burden of both tuberculosis(TB)and multidrug-resistant TB(MDRTB)based on the WHO Global TB Report *** the available data suggest that the total TB incidence has declined,the absolute number of new cases is still *** number of reported TB cases in India in 2018 was 2.2 million,which was 1.5 million in *** 47%increment in TB case notification in India within a decade shows a persistent public health *** contributes about 22%of the World's TB *** National Strategic Plan 2017e2025,sets out the government plans to eliminate TB by ***,the milestone seems unrealistic to achieve the TB eradication goal by *** developed a five-dimensional mathematical model to understand the TB dynamics in India and investigate the possibility of the earliest TB eradication time *** model stratifies the entire TB class into three different classes as drug-sensitive(DS),MDR,and isolated *** effective reproduction number,equilibrium points,and stability analysis of the model were carried *** model predicts the total estimated cases of DS-TB and MDR-TB from 2018 to 2035 through numerical simulation and suggests that TB may be eliminated by 2035 in India if the treatment success rate could be achieved to 95%,by contact tracing and isolating at least 50%of MDR-TB.

关键词： Multi-drug resistant Drug-sensitive Isolation Reproduction number Mathematical modelling

Analyzing the Implications of COVID-19 Pandemic through an Intelligent-Computing Technique

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Computer Systems Science & Engineering 2022年第6期41卷 959-974页

作者： Abhishek Kumar Pandey Jehad F.Al-Amri Ahmad F.Subahi Rajeev Kumar Raees Ahmad Khan Department of Information Technology Babasaheb Bhimrao Ambedkar UniversityLucknow226025India Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Science University College of Al JamoumUmm Al Qura UniversityMakkah21421Saudi Arabia Department of Computer Applications Shri Ramswaroop Memorial UniversityBarabanki225003India

The outbreak of Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2 virus or COVID-19) disease was declared pandemic by the WorldHealth Organization (WHO) on March 11, 2020. COVID-19 has already affectedmore than 211 nations. In such a bleak scenario, it becomes imperative to analyzeand identify those regions in Saudi Arabia that are at high risk. A preemptivestudy done in the context of predicting the possible COVID-19 hotspots wouldfacilitate in the implementation of prompt and targeted countermeasures againstSARS-CoV-2, thus saving many lives. Working towards this intent, the presentstudy adopts a decision making based methodology of simulation named Analytical Hierarchy Process (AHP), a multi criteria decision making approach, forassessing the risk of COVID-19 in different regions of Saudi Arabia. AHP givesthe ability to measure the risks numerically. Moreover, numerical assessments arealways effective and easy to understand. Hence, this research endeavour employsFuzzy based computational method of decision making for its empirical *** in the proposed paper suggest that Riyadh and Makkah are the mostsusceptible regions, implying that if sustained and focused preventive measuresare not introduced at the right juncture, the two cities could be the worst afflictedwith the infection. The results obtained through Fuzzy based computationalmethod of decision making are highly corroborative and would be very usefulfor categorizing and assessing the current COVID-19 situation in the Kingdomof Saudi Arabia. More specifically, identifying the cities that are likely to beCOVID-19 hotspots would help the country’s health and medical fraternity toreinforce intensive containment strategies to counter the ills of the pandemic insuch regions.

关键词： COVID-19 Saudi Arabian regions risk assessment dynamics of infection fuzzy AHP

Integrating Blockchain Technology into Healthcare Through an Intelligent Computing Technique

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Computers, Materials & Continua 2022年第2期70卷 2835-2860页

作者： Asif Irshad Khan Abdullah Saad Al-Malaise ALGhamdi Fawaz Jaber Alsolami Yoosef B.Abushark Abdulmohsen Almalawi Abdullah Marish Ali Alka Agrawal Rajeev Kumar Raees Ahmad Khan Department of Computer Science Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Information Systems Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Information Technology Babasaheb Bhimrao Ambedkar UniversityLucknow226025Uttar PradeshIndia Department of Computer Applications Shri Ramswaroop Memorial UniversityBarabanki225003Uttar PradeshIndia

The blockchain technology plays a significant role in the present era of information *** the last few years,this technology has been used effectively in several *** has already made significant differences in human life,as well as is intended to have noticeable impact in many other domains in the forthcoming *** rapid growth in blockchain technology has created numerous new possibilities for use,especially for healthcare *** digital healthcare services require highly effective security methodologies that can integrate data security with the availablemanagement *** test and understand this goal of security management in Saudi Arabian perspective,the authors performed a numerical analysis and simulation through a multi criteria decision making approach in this *** authors adopted the fuzzy Analytical Hierarchy Process(AHP)for evaluating the effectiveness and then applied the fuzzy Technique forOrder of Preference by Similarity to Ideal Solution(TOPSIS)technique to simulate the validation of *** eliciting highly corroborative and conclusive results,the study referred to a real time project of diabetes patients’management application of Kingdom of Saudi Arabia(KSA).The results discussed in this paper are scientifically proven and validated through various analysis *** the present study can be a credible basis for other similar endeavours being undertaken in the domain of blockchain research.

关键词： Blockchain technology data management fuzzy logic AHP TOPSIS

Hesitant Fuzzy-Sets Based Decision-Making Model for Security Risk Assessment

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Computers, Materials & Continua 2022年第2期70卷 2297-2317页

作者： Ahmed S.Alfakeeh Abdulmohsen Almalawi Fawaz Jaber Alsolami Yoosef B.Abushark Asif Irshad Khan Adel Aboud S.Bahaddad Alka Agrawal Rajeev Kumar Raees Ahmad Khan Department of Information Systems Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Computer Science Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Information Technology Babasaheb Bhimrao Ambedkar UniversityLucknow226025Uttar PradeshIndia Department of Computer Applications Shri Ramswaroop Memorial UniversityLucknow-Deva RoadBarabanki225003Uttar PradeshIndia

Security is an important component in the process of developing healthcare web *** need to ensure security maintenance;therefore the analysis of healthcare web application’s security risk is of utmost *** must be considered to minimise the security ***,security risk management activities are revised,prepared,implemented,tracked,and regularly set up efficiently to design the security of healthcare web *** the security risk of a healthcare web application must be considered as the key *** is,in specific,seen as an add-on during the development process of healthcare web applications,but not as the key *** must ensure that security is taken into account right from the earlier developmental stages of the healthcare web *** this row,the authors of this study have used the hesitant fuzzy-based AHP-TOPSIS technique to estimate the risks of various healthcare web applications for improving *** approach would help to design and incorporate security features in healthcare web applications that would be able to battle threats on their own,and not depend solely on the external security of healthcare web ***,in terms of healthcare web application’s security-durability,the security risk variable is measured,and vice ***,the findings of our study will also be useful in improving the durability of several web applications in healthcare.

关键词： Web applications security risk security durability hesitantbased decision-making approach

Hybrid Computational Modeling for Web Application Security Assessment

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Computers, Materials & Continua 2022年第1期70卷 469-489页

作者： Adil Hussain Seh Jehad F.Al-Amri Ahmad F.Subahi Md Tarique Jamal Ansari Rajeev Kumar Mohammad Ubaidullah Bokhari Raees Ahmad Khan Department of Information Technology Babasaheb Bhimrao Ambedkar UniversityLucknow226025Uttar PradeshIndia Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Science University College of Al JamoumUmm Al Qura UniversityMakkah21421Saudi Arabia Department of Computer Applications Shri Ramswaroop Memorial UniversityBarabanki225003Uttar PradeshIndia Department of Computer Science Aligarh Muslim UniversityAligarh202002Uttar PradeshIndia

Transformation from conventional business management systems to smart digital systems is a recurrent trend in the current *** has led to digital revolution,and in this context,the hardwired technologies in the software industry play a significant role However,from the beginning,software security remains a serious issue for all levels of *** vulnerabilities lead to intrusions that cause data breaches and result in disclosure of sensitive data,compromising the organizations’reputation that translates into,financial losses as *** of the data breaches are financially motivated,especially in the healthcare *** cyber invaders continuously penetrate the E-Health data because of the high cost of the data on the dark ***,security assessment of healthcare web-based applications demands immediate intervention mechanisms to weed out the threats of *** aim of this work is to provide efficient and effective healthcare web application security *** study has worked with the hybrid computational model of Multi-Criteria Decision Making(MCDM)based on Analytical Hierarchy Process(AHP)and Technique for Order of Preference by Similarity to Ideal-Solutions(TOPSIS)under the Hesitant Fuzzy(HF)*** fuzzy sets provide effective solutions to address decision making problems where experts counter hesitation to make a *** proposed research endeavor will support designers and developers in identifying,selecting and prioritizing the best security attributes for web applications’*** empirical analysis concludes that Robustness got highest priority amongst the assessed security attributes set followed by Encryption,Authentication,Limit Access,Revoke Access,Data Validation,and Maintain Audit *** results of this research endeavor depict that this proposed computational procedure would be the most conversant mechanism for determining the web application *** study also establishes g

关键词： Healthcare web application security assessment hesitant fuzzy sets AHP-TOPSIS

Evaluating the Impacts of Security-Durability Characteristic:Data Science Perspective

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Computer Systems Science & Engineering 2022年第5期41卷 557-567页

作者： Abdullah Alharbi Masood Ahmad Wael Alosaimi Hashem Alyami Alka Agrawal Rajeev Kumar Abdul Wahid Raees Ahmad Khan Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Information Technology Babasaheb Bhimrao Ambedkar UniversityLucknow226025India Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Applications Shri Ramswaroop Memorial UniversityBarabanki225003India Department of Computer Science and Information Technology Maulana Azad National Urdu UniversityHyderabad500032India

Since the beginning of web applications,security has been a critical study *** has been a lot of research done to figure out how to define and identify security goals or ***,high-security web apps have been found to be less durable in recent years;thus reducing their business *** security features of a web application are worthless unless they provide effective services to the user and meet the standards of commercial ***,there is a necessity to link in the gap between durability and security of the web ***,security mechanisms must be used to enhance durability as well as the security of the web *** durability and security are not related directly,some of their factors influence each other *** play an important role in reducing the void between durability and *** this respect,the present study identifies key characteristics of security and durability that affect each other indirectly and directly,including confidentiality,integrity availability,human trust and *** importance of all the attributes in terms of their weight is essential for their influence on the whole security during the development procedure of web *** estimate the efficacy of present study,authors employed the Hesitant Fuzzy Analytic Hierarchy Process(H-Fuzzy AHP).The outcomes of our investigations and conclusions will be a useful reference for the web application developers in achieving a more secure and durable web application.

关键词： Software security durability durability of security services web application development process

Analytical modeling of subthreshold current and subthreshold swing of Gaussiandoped strained-Si-on-insulator MOSFETs

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Journal of Semiconductors 2014年第8期35卷 52-59页

作者： Gopal Rawat Sanjay Kumar Ekta Goel Mirgender Kumar Sarvesh Dubey S.Jit Department of Electronics Engineering Indian Institute of Technology (BHU) Varanasi India Faculty of Electronics and Communication Engineering Shri Ramswaroop Memorial University Lucknow-Deva Road India

This paper presents the analytical modeling of subthreshold current and subthreshold swing of short- channel fully-depleted （FD） strained-Si-on-insulator （SSOI） MOSFETs having vertical Gaussian-like doping pro- file in the channel. The subthreshold current and subthreshold swing have been derived using the parabolic approx- imation method. In addition to the effect of strain on silicon layer, various other device parameters such as channel length （L）, gate-oxide thickness （tox）, strained-Si channel thickness （ts_Si）, peak doping concentration （Np）, project range （Rp） and straggle （op） of the Gaussian profile have been considered while predicting the device characteris- tics. The present work may help to overcome the degradation in subthreshold characteristics with strain engineering. These subthreshold current and swing models provide valuable information for strained-Si MOSFET design. Ac- curacy of the proposed models is verified using the commercially available ATLASTM, a two-dimensional （2D） device simulator from SILVACO.

关键词： strained-Si-on-insulator (SSOI) Poisson's solution short-channel-effects

Fractal dynamics and computational analysis of local fractional Poisson equations arising in electrostatics

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Communications in Theoretical Physics 2023年第12期75卷 12-18页

作者： Jagdev Singh Hassan Kamil Jassim Devendra Kumar Ved Prakash Dubey Department of Mathematics JECRC UniversityJaipurRajasthanIndia Department of Mathematics Kyung Hee University26 Kyungheedae-roDongdaemun-guSeoul02447Republic of Korea Department of Computer Science and Mathematics Lebanese American UniversityBeirutLebanon Department of Mathematics Faculty of Education for Pure SciencesUniversity of Thi-QarNasiriyahIraq Department of Mathematics University of RajasthanJaipur-302004RajasthanIndia Faculty of Mathematical and Statistical Sciences Shri Ramswaroop Memorial UniversityBarabanki-225003Uttar PradeshIndia

In this paper,the local fractional natural decomposition method(LFNDM)is used for solving a local fractional Poisson *** local fractional Poisson equation plays a significant role in the study of a potential field due to a fixed electric charge or mass density *** examples with computer simulations are presented in this *** obtained results show that LFNDM is effective and convenient for application.

关键词： poisson equation local fractional natural transform adomian decomposition method local fractional derivative electrostatics fractal media