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Particuology 2024年第7期90卷 307-322页

作者： Omid Afsari Kamyar Hashemnia School of Mechanical Engineering Shiraz UniversityMolla Sadra St.ShirazIran

This article investigates the combined effect and the order of influence of feed rate,inclination angle,vibration amplitude,frequency,and angle on the efficiency and mesh wear rate of a linear vibrating screen,as well as the average velocity,and mass of the accumulated *** discrete element modeling simulations were conducted using LIGGGHTS open-source code to analyze particles *** Taguchi method was employed to evaluate the combined effect of the ***,the simulation results were analyzed using analysis of *** optimal values of the parameters for maximising efficiency and minimising mesh wear were determined using grey relational *** results indicated that the most effective parameters on screening efficiency and average velocity of particles were the inclination angle,vibration angle,frequency,amplitude,and feed rate,*** most influential parameters on screen mesh wear rate were feed rate,inclination angle,vibration angle,frequency,and amplitude,respectively.

关键词： Discrete element modeling Granular material Taguchi method Vibrating screen Wear

Hepatoprotective effect of Holothuria leucospilota methanolic extract on dimethyl nitrosamine-induced hepatotoxicity in rats

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ANIMAL MODELS AND EXPERIMENTAL MEDICINE 2024年第4期7卷 544-552页

作者： Dejan, Fatemeh Daneshi, Amineh Aslani, Javad Rajabi Ahmadi, Nasrollah Roozbahani, Narges Eskandari Rahmanian, Elaham Behmanesh, Reza Gheisari, Hamid Reza shiraz univ Sch Vet Med Dept Basic Sci Shiraz Iran Farzanegan High Sch Dept Educ Tehran Kohgiluyeh & Bo Iran shiraz univ Sch Vet Med Food Hyg Dept Shiraz Iran shiraz univ Sch Vet Med Dept Pathol Shiraz Iran Kermanshah univ Med Sci Imam Reza Hosp Clin Res Dev Ctr Kermanshah Iran shiraz univ Med Sci Mol Dermatol Res Ctr Shiraz Iran shiraz univ Med Sci Sch Med Dept Anat Shiraz Iran Islamic Azad univ Fac Vet Med Dept Pathobiol Garmsar Branch Garmsar Iran

Background: Complementary medicine is an interesting field for extracting bioactive compounds from various plant and animal sources. The hepatoprotective effect of the methanolic extract of a species of sea cucumber called Holothuria leucospilota in an animal model of liver cancer caused by dimethyl nitrosamine (DMN) was studied. Methods: Wistar female rats were randomly divided into five groups (n = 12): control (intact), positive control (received 1% DMN [10 mg/kg/week, intraperitoneally] for 12 weeks), and three treatment groups (received 50, 100, and 200 mg/kg/day H. leucospilota extract orally for 12 weeks along with intraperitoneal administration of 1% DMN [10 mg/kg/week]). In all groups, ultrasound was performed on the liver every week to check its density. Blood sampling and liver isolation were performed on three occasions, at 4, 8, and 12 weeks, to check liver enzymes and the histopathological condition of the liver tissue (every week, four animals from each group were randomly selected). Results: Liver density changes were evident from the eighth week onward in the positive control group. Histopathological results indicated pathologic changes in the positive control group after 4 weeks. The increase in liver enzymes in the positive control group was significantly different from that in the treatment and control groups. Conclusions: We demonstrated the hepatoprotective effect of H. leucospilota on DMN-induced liver damage in rats using biochemical and histological parameters and ultrasonography. More additional research (in silico or in vitro) is needed to find the exact mechanism and the main biological compound in H. leucospilota.

关键词： dimethyl nitrosamine hepatotoxicity Holothuria leucospilota sea cucumber SEA-CUCUMBER HEPATOCELLULAR-CARCINOMA TRITERPENE GLYCOSIDES MOLECULAR-IDENTIFICATION STICHOPUS-HORRENS

Nonlinear wave dispersion in monoatomic chains with lumped and distributed masses:discrete and continuum models

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 633-648页

作者： E.GHAVANLOO S.EL-BORGI School of Mechanical Engineering Shiraz UniversityShiraz 71963-16548Iran Mechanical Engineering Program Texas A&M University at QatarDoha 23874Qatar

The main objective of this paper is to investigate the influence of inertia of nonlinear springs on the dispersion behavior of discrete monoatomic chains with lumped and distributed *** developed model can represent the wave propagation problem in a non-homogeneous material consisting of heavy inclusions embedded in a *** inclusions are idealized by lumped masses,and the matrix between adjacent inclusions is modeled by a nonlinear spring with distributed ***,the model is capable of depicting the wave propagation in bi-material bars,wherein the first material is represented by a rigid particle and the second one is represented by a nonlinear spring with distributed *** discrete model of the nonlinear monoatomic chain with lumped and distributed masses is first considered,and a closed-form expression of the dispersion relation is obtained by the second-order Lindstedt-Poincare method(LPM).Next,a continuum model for the nonlinear monoatomic chain is derived directly from its discrete lattice model by a suitable continualization *** subsequent use of the second-order method of multiple scales(MMS)facilitates the derivation of the corresponding nonlinear dispersion relation in a closed *** novelties of the present study consist of(i)considering the inertia of nonlinear springs on the dispersion behavior of the discrete mass-spring chains;(ii)developing the second-order LPM for the wave propagation in the discrete chains;and(iii)deriving a continuum model for the nonlinear monoatomic chains with lumped and distributed ***,a parametric study is conducted to examine the effects of the design parameters and the distributed spring mass on the nonlinear dispersion relations and phase velocities obtained from both the discrete and continuum *** parameters include the ratio of the spring mass to the lumped mass,the nonlinear stiffness coefficient of the spring,and the wave amplitude.

关键词： nonlinear mass-spring chain discrete model continuum model LindstedtPoincare method(LPM) method of multiple scales(MMS) dispersion phase velocity

Prediction of the burden of road traffic injuries in Iran by 2030: Prevalence, death,and disability-adjusted life years

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Chinese Journal of Traumatology 2024年第4期27卷 242-248页

作者： Mozhgan Seif Sedigheh Edalat Ali Majidpour Azad shirazi Somayeh Alipouri Mohsen Bayati Non-communicable Diseases Research Center Department of EpidemiologySchool of HealthShiraz University of Medical SciencesShirazIran Health Human Resources Research Center School of Health Management and Information SciencesShiraz University of Medical SciencesShirazIran Health Policy Research Center Institute of HealthShiraz University of Medical SciencesShirazIran

Purpose:Road traffic accidents pose a global challenge with substantial human and economic *** a high incidence of road traffic injuries,leading to a significant burden on *** studyaims to predict the future burden of road traffic injuries in Iran until 2030,providing valuable insights forpolicy-making and interventions to improve road safety and reduce the associated human and ***:This analytical study utilized time series models,specifically autoregressive integrated movingaverage(ARIMA)and artificial neural networks(ANNs),to predict the burden of road traffic accidents byanalyzing past data to identify patterns and trends in Iran until *** required data related toprevalence,death,and disability-adjusted life years(DALYs)rates were collected from the Institute forHealth Metrics and Evaluation database and analyzed using R software and relevant modeling andstatistical analysis ***:Both prediction models,ARIMA and ANNs indicate that the prevalence rates(per 100,000)of allroad traffic injuries,except for motorcyclist road injuries which have an almost flat trend,remaining ataround 430,increase by *** on estimations of both models,the rates of death and DALYs due tomotor vehicle and pedestrian road traffic injuries *** motor vehicle road injuries,estimatedtrends decrease to approximately 520 DALYs and 10 ***,for pedestrian road injuries these ratesreached approximately 300 DALYs and 6 deaths,according to the *** cyclists and other roadtraffic injuries,the predicted DALY rates by the ANN model increase to almost 50 and 8,while predictionsconducted by the ARIMA model show a static trend,remaining at 40 and approximately ***,these rates for the prediction of death rate by the ANN model increased to 0.6 and 0.1,while predictionsconducted by the ARIMA model show a static trend,remaining at 0.43 and *** to the ANNmodel,the predicted rates of DALY and death for m

关键词： Accidents Traffic Accident prevention Motorcycles Road injury Forecasting

Protective effect of co-enzyme Q10 on testicular tissue and sperm parameters in adult male rats treated with Sunset Yellow FCF

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Asian pacific Journal of Reproduction 2024年第2期13卷 80-88页

作者： Rohollah Nazari Somayeh Akbari Maryam Naseh Shayan Yousufzai Seyede Fatemeh Hosseini Fatemeh Karimi Histomorphometry and Stereology Research Center Shiraz University of Medical SciencesShirazIran Anatomy Department School of MedicineShiraz University of Medical SciencesShirazIran Student Research Committee Medical SchoolShiraz University of Medical SciencesShirazIran Faculty of Tabas School of NursingBirjand University of Medical SciencesBirjandIran

Objective:To determine the protective effect of co-enzyme Q10(CoQ10)on testicular tissue and sperm parameters in male rats treated with SunsetYellow ***:Sixty male Sprague-Dawley rats were randomly divided into 6 groups of the control,CoQ10(10 mg/kg/day),low dose of Sunset Yellow(2.5 mg/kg),high dose of Sunset Yellow(70 mg/kg),low dose of Sunset Yellow(2.5 mg/kg)plus CoQ10,and high dose of Sunset Yellow(70 mg/kg)plus *** drugs were administered via daily oral gavages for 6 *** the end of the experiment,sperm analysis,stereological and histological assessments of the testis were carried ***:The normal morphology(by 41.1%)and progressive spermatozoa(by 74.8%),testicle volume(by 33.4%),lumen volume(by 38.3%),interstitial tissue volume(by 44.7%),seminiferous tubule volume(by 40.7%),and number of spermatogonia(by 53.9%)and Leydig cells(by 70.7%)reduced in the rats that received high doses of Sunset Yellow in comparison to the control ***,all these alterations were recovered by CoQ10 treatment in the CoQ10 plus high dose of Sunset Yellow ***,low doses of Sunset Yellow did not affect different parameters of the testis and ***:CoQ10 could,to some extent,prevent structural changes of the testis induced by the high dose of SunsetYellow.

关键词： Sunset Yellow FCF Co-enzyme Q10 Testicle Sperm Stereology

Evaluation of the seismic behavior of reinforced concrete structures with flat slab-column gravity frame and shear walls through nonlinear analysis methods

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 713-726页

作者： M.A.Najafgholipour S.Heidarian Radbakhsh E.Erfani Department of Civil and Environmental Engineering Shiraz University of TechnologyShiraz ***Iran Department of Building Civiland Environmental EngineeringConcordia UniversityMontréal H3G 1M8Canada

This paper presents an investigation of the seismic behavior of reinforced concrete(RC)structures in which shear walls are the main lateral load-resisting elements and the participation of flat slab floor systems is not considered in the seismic design *** this regard,the behavior of six prototype structures(with different heights and plan layouts)is investigated through nonlinear static and time history analyses,implemented in the OpenSees *** results of the analyses are presented in terms of the behavior of the slab-column connections and their mode of failure at different loading ***,the global response of the buildings is discussed in terms of some parameters,such as lateral overstrength due to the gravity flat slab-column *** to the nonlinear static analyses,in structures in which the slab-column connections were designed only for gravity loads,the slab-column connections exhibited a punching mode of failure even in the early stages of ***,the punching failure was eliminated in structures in which a minimum transverse reinforcement recommended in ACI 318(2019)was provided in the slabs at joint ***,despite neglecting the contribution of gravity flat slab-column frames in the lateral load resistance of the structures,a relatively significant overstrength was imposed on the structures by the gravity frames.

关键词： RC flat slab-column frames seismic behavior nonlinear analysis time history analysis

Outcomes of surgical correction of Peyronie’s disease with plaque excision and grafting: Comparison of testicular tunica vaginalis graft versus bovine pericardium graft

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Asian Journal of Urology 2024年第3期11卷 497-503页

作者： Ali Eslahi Faisal Ahmed Mohammad Reza Askarpour Hossein-Ali Nikbakht Iman Shamohammadi Payam Ghasemi Hanieh Alimardani Bahareh Ebrahimi Department of Urology School of MedicineShiraz University of Medical SciencesShirazIran shiraz Geriatric Research Center Shiraz University of Medical SciencesShirazIran Urology Research Center Al-Thora General HospitalDepartment of UrologySchool of MedicineIbb University of Medical SciencesIbbYemen Social Determinants of Health Research Center Health Research InstituteBabol University of Medical SciencesBabolIran

Objective:Peyronie’s disease(PD)is an abnormal wound healing in the penile tunica *** fibrotic plaque excision,different graft materials have been used to repair the defects,but the optimal graft remains *** study aimed to compare the functional outcomes of testicular tunica vaginalis grafts and bovine pericardium grafts in patients with severe ***:A retrospective comparative study was conducted on 33 PD patients undergoing partial plaque excision and grafting from September 2015 to May *** patients were divided into two groups depending on the type of graft *** 15 patients in Group B,testicular tunica vaginalis grafts were used to repair the defect,while for 18 patients in Group A,bovine pericardium grafts were *** of the patient’s age,comorbidities,sexual function,penile curvature,postoperative complications,need for further treatment,change in penile length,and satisfaction were gathered and compared between the *** function was evaluated using the 5-item version of the International Index of Erectile Function(IIEF-5),and a functional less than 20-degree penile curvature after surgery was considered a successful ***:There was no difference in age,comorbidities,degree of curvature,perioperative IIEF-5,operative time,plaque size,or complication *** surgery,a statistically significant improvement in curvature degree(p<0.05)and satisfactory penile appearance(p<0.05)were seen in both groups without any superiority between the two groups(p=0.423 and p=0.840,respectively).With a 30-month follow-up,the IIEF-5 was consistent in both groups,with no statistical significance between the groups(p=0.492).The main change in penile length during the operation was increased and still positive in the last follow-up in both groups without statistical significance(p=0.255 and p=0.101,respectively).Conclusion:Partial plaque excision and corporoplasty with both testicular tunica vaginalis or bovine pericard

关键词： Peyronie's disease Plaqueexcision Testiculartunica vaginalis graft Bovinepericardium graft

Efficacy of tadalafil on improvement of men with erectile dysfunction caused by COVID-19:A randomized placebo-controlled trial

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Asian Journal of Urology 2024年第1期11卷 128-133页

作者： Iman Shamohammadi Seyedmohammad Kazemeyni Mohammadali Sadighi Tara Hasanzadeh Alireza Dizavi Department of Urology Nemazee HospitalShiraz University of Medical ScienceShirazIran Department of Urology Shariati HospitalTehran University of Medical ScienceTehranIran

Objective: According to the high prevalence of COVID-19 and the subsequent risk of men's sexual health, we decided to investigate the efficacy of tadalafil on improvement of men with erectile dysfunction caused by ***: In this study, 70 outpatients who were recovered from COVID-19 without acute respiratory distress syndrome with negative polymerase chain reaction test and a complaint of erectile dysfunction were divided into two groups: 35 patients who received tadalafil 5 mg daily and 35 who received placebo. For each patient, basic assessment of sexual function was performed using the 5-item version of the International Index of Erectile Function (IIEF-5) questionnaire. Then, treatment was started from 2 months after complete recovery of COVID-19 with negative polymerase chain reaction test for 3 months. At the end of the treatments, the patients were re-evaluated for sexual function using the complete version of IIEF questionnaire. Finally, the results before and after treatment in the intervention group were compared with those of the control ***: Treatment with both tadalafil and placebo improved the patients' sexual function criteria compared to the baseline. However, this improvement was significantly higher in the intervention group with tadalafil than the control group with placebo (p<0.05).Conclusion: Daily administration of tadalafil 5 mg seems to be effective and safe for improvement of erectile dysfunction caused by COVID-19.

关键词： Tadalafil Erectile dysfunction COVID-19 Sexual function

Correlation between critical thinking and emotional intelligence:a national crosssectional study on operating room nursing students in Iran

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Frontiers of Nursing 2024年第1期11卷 99-104页

作者： Armin Fereidouni Esmaeil Teymoori Tayebeh Bahmani Hamid Reza Sabet Zahra Maleki Mina Gharibi Department of Operating Room Technology Community Based Psychiatric Care Research CenterSchool of Nursing and MidwiferyShiraz University of Medical SciencesShirazIran Department of Operating Room Technology School of Paramedical SciencesAJA University of Medical SciencesTehranIran Department of Operating Room School of Allied Medical ScienceFasa University of Medical SciencesFasaIran Clinical Education Research Center Shiraz University of Medical SciencesShirazIran Medical Journalism Department School of Paramedical SciencesShiraz University of Medical SciencesShirazIran Department of Epidemiology Student Research CommitteeShiraz University of Medical SciencesShirazIran

Objective:According to the World Federation of Medical Education,critical thinking should be part of the training of medical and paramedical *** can improve the quality of care of patients after surgery by having or acquiring this skill in health ***,Emotional intelligence is introduced as an impor tant and effective factor on the professional performance and mental health of healthcare ***,the present study was designed and implemented to determine the relationship between emotional intelligence and critical thinking among operating room nursing students of medical sciences universities in ***:This cross-sectional study was done on 420 operating room students in 10 top medical sciences universities of Iran in *** sampling method in this research was multistage *** data collection instruments included demographic characteristics,Rickett's critical thinking,and Bradberry-Greaves'emotional intelligence *** receiving the ethics code,data collection was done for 2 *** data analysis,descriptive and inferential analyses including independent t-tests,analysis of variance,and Pearson correlation were *** collected data were analyzed by SPSS 18(IBM Corporation,Armonk,New York,United States).P-value<0.05 was considered ***:The mean age of the students participating in this study was 23.02±3.70 years,with women constituting 67.4%of *** results of data analysis indicated that the mean total score of critical thinking and emotional intelligence was 124.10±37.52 and 114.12±43.63,respectively.A direct significant correlation between critical thinking and emotional intelligence(r=0.459,P-value<0.001)and a significant relationship between gender and emotional intelligence(P-value=0.028)were ***:Based on the present study results,educational managers in the Ministry of Health are suggested to consider suitable educational programs for improving critical think

关键词： critical thinking emotional intelligence operating room students operating room nurses

Sacrificial piles as a countermeasure against local scour around underwater pipelines

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Water Science and Engineering 2024年第2期17卷 187-196页

作者： Forough Raeisi Seyed Mohammad Ali Zomorodiann Masih Zolghadr Hazi Mohammad Azamathulla Department of Water Engineering Shiraz UniversityShiraz ***Iran Department of Water Sciences Engineering Jahrom UniversityJahrom ***Iran Department of Civil and Environmental Engineering The University of the West IndiesSt.Augustine CampusTrinidad 331310Republic of Trinidad and Tobago

Local scour around pipelines crossing rivers or in marine environments is a significant *** can lead to failure of the pipelines resulting in environmental side effects and economic *** study developed an experimental method to reduce local scour around pipelines with a steady flow of clear water by installing cylindrical and cubical sacrificial *** sizes of sacrificial piles were examined in a linear *** piles were installed on the upstream side of the pipeline at three *** scour depth reduction rates below the pipeline were *** results showed that sacrificial piles could protect a pipeline from local scour.A portion of scoured sediment around the sacrificial piles was deposited beneath the *** sediment accumulation reduced the scour depth beneath the *** of the experimental results demonstrated that the size of piles(d),the spacing between piles,and the distance between the pipe and piles(Xp)were the variables that reduced the maximum scour beneath the pipeline with a diameter of *** the piles with d=0.40D and 0.64D,X_(p)=4OD was the optimal distance to install a group of piles,and cubical piles could mitigate scour more effectively than cylindrical piles under similar *** the piles with d=D,the greatest reduction in scour depth was achieved at X_(p)=50D with any desired spacings between piles,and cylindrical piles in this dimension could protect the pipeline against scour more effectively than cubical piles.

关键词： Clear water River crossing pipeline Local scour Self-burial process Sediment transport