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SecIngress:An API Gateway Framework to Secure Cloud Applications Based on N-Variant System

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China Communications 2021年第8期18卷 17-34页

作者： dacheng Zhou Hongchang Chen Guozhen Cheng Weizhen He Lingshu Li National digital Switching System Engineering and Technological r&d center ZhengzhouHenan 450002China

Based on the diversified technology and the cross-validation mechanism,the N-variant system provides a secure service architecture for cloud providers to protect the cloud applications from attacks by executing multiple variants of a single software in parallel and then checking their behaviors’consistency.However,it is complex to upgrade current Software as a Service(SaaS)applications to adapt N-variant system architecture.Challenges arise from the inability of tenants to adjust the application architecture in the cloud environment,and the difficulty for cloud service providers to implement N-variant systems using existing API gateways.This paper proposes SecIngress,an API gateway framework,to overcome the challenge that it is hard in the cloud environment to upgrade the applications based on N-variants system.We design a two-stage timeout processing method to lessen the service latency and an Analytic Hierarchy Process Voting under the Metadata mechanism(AHPVM)to enhance voting accuracy.We implement a prototype in a testbed environment and analyze the security and performance metrics before and after deploying the prototype to show the effectiveness of SecIngress.The results reveal that SecIngress enhances the reliability of cloud applications with acceptable performance degradation.

关键词： N-variant system API gateway cloud security analytic hierarchy process

How do Precision Medicine and System Biology response to Human Body's Complex Adaptability？

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Chinese Journal of Integrative Medicine 2016年第12期22卷 883-888页

作者：袁冰 hong kong modern chinese medicine r&d center Hong Kong SARChina

In the field of life sciences, although system biology and ＂precision medicine＂ introduce some complex scientific methods and techniques, it is still based on the ＂analysis–reconstruction＂ of reductionist theory as a whole. Adaptability of complex system increase system behaviour uncertainty as well as the difficulties of precise identification and control. It also put systems biology research into trouble. To grasp the behaviour and characteristics of organism fundamentally, systems biology has to abandon the ＂analysis–reconstruction＂ concept. In accordance with the guidelines of complexity science, systems biology should build organism model from holistic level, just like the Chinese medicine did in dealing with human body and disease. When we study the living body from the holistic level, we will find the adaptability of complex system is not the obstacle that increases the difficulty of problem solving. It is the ＂exceptional＂, ＂right-hand man＂ that helping us to deal with the complexity of life more effectively.

关键词： precision medicine complexity science adaptability system biology personalized medicine

Glycoside-specific metabolomics combined with precursor isotopic labeling for characterizing plant glycosyltransferases

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Molecular Plant 2022年第10期15卷 1517-1532页

作者： Jie Wu Wentao Zhu Xiaotong Shan Jinyue Liu Lingling Zhao Qiao Zhao shenzhen Key Laboratory of Synthetic Genomics Guangdong Provincial Key Laboratory of Synthetic GenomicsCAS Key Laboratory of Quantitative Engineering BiologyShenzhen Institute of Synthetic BiologyShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Innovation center of Pesticide research Department of Applied ChemistryCollege of ScienceChina Agricultural UniversityBeijing 100193China center for Plant Biology School of Life SciencesTsinghua UniversityBeijing 100084China

Glycosylation by uridine diphosphate-dependent glycosyltransferases(UGTs)in plants contributes to the complexity and diversity of secondary metabolites.UGTs are generally promiscuous in their use of acceptors,making it challenging to reveal the function of UGTs in vivo.Here,we described an approach that combined glycoside-specific metabolomics and precursor isotopic labeling analysis to characterize UGTs in Arabidopsis.We revisited the UGT72E cluster,which has been reported to catalyze the glycosylation of monolignols.Glycoside-specific metabolomics analysis reduced the number of differentially accumulated metabolites in the ugt72e1e2e3 mutant by at least 90%compared with that from traditional untargeted metabolomics analysis.In addition to the two previously reported monolignol glycosides,a total of 62 glycosides showed reduced accumulation in the ugt72e1e2e3 mutant,22 of which were phenylalanine-derived glycosides,including 5-OH coniferyl alcohol-derived and lignan-derived glycosides,as confirmed by isotopic tracing of[^(13)C_(6)]-phenylalanine precursor.Our method revealed that UGT72Es could use coumarins as substrates,and genetic evidence showed that UGT72Es endowed plants with enhanced tolerance to low iron availability under alkaline conditions.Using the newly developed method,the function of UGT78d2 was also evaluated.These case studies suggest that this method can substantially contribute to the characterization of UGTs and efficiently investigate glycosylation processes,the complexity of which have been highly underestimated.

关键词： glycosyltransferases glycosides-specific metabolomics precursor isotopic labeling glucoside Arabidopsis thaliana phenylpropanoid coumarins

Characterization of edible bird’s nest by peptide fingerprinting with principal component analysis

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Food Quality and Safety 2017年第1期1卷 83-92页

作者： Chun-Fai Wong Gallant Kar-Lun Chan Ming-Lu Zhang Ping Yao Huang-Quan Lin Tina Ting-Xia dong Geng Li Xiao-Ping Lai Karl Wah-Keung Tsim division of Life Science and center for Chinese Medicine r&d The Hong Kong University of Science and TechnologyClear Water BayKowloon HKUST shenzhen research Institute Hi-Tech ParkNanshan School of Chinese Herbal Medicine Guangzhou University of Chinese Medicine dongguan Mathematical Engineering Academy of Chinese Medicine Guangzhou University of Chinese MedicineChina

OBJECTIVES:Proteins are the major component and play a key role in nutritious and therapeutic functions of edible bird’s nest(EBN);however,limited studies have been conducted on the protein due to difficulties in extraction,isolation as well as identification.This study aimed to provide comprehensive information for the quality evaluation of EBN peptides,which would be a valuable reference for further study on EBN proteins.METHOdS:Here,we developed a quality control method using high performance liquid chromatography(HPLC)peptide fingerprints deriving from EBN being digested with simulated gastric fluid.The characteristic peptide peaks were collected and identified by LC-MS/MS.rESULTS:The characteristic peptide peaks,corresponding to the protein fragments of acidic mammalian chitinase-like,lysyl oxidase,and Mucin-5AC-like,were identified and quantified.Interestingly,the principal component analysis indicated that the fingerprints were able to discriminate colour of EBN(white/red)and production sites(cave/house)of White EBN on the same weight basis.As proposed by the model developed in this study,Muc-5AC-like and AMCaselike proteins were the markers with the highest discriminative power.CONCLUSIONS:The overall findings suggest that HPLC peptide fingerprints were able to clearly demonstrate peptide profile differences between genuine and adulterated EBN samples;and classify EBN samples by its color and production site.In addition,the protein identification results suggested that Muc-5AC-like protein was the major protein in EBN.

关键词： Edible bird’s nest Peptide fingerprint Mucin-5AC-like Acidic mammalian chitinase-like Principal component analysis

LdAS&ET-Ad:Learnable distillation Attack Strategies and Evolvable Teachers Adversarial distillation

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Computers, Materials & Continua 2024年第5期79卷 2331-2359页

作者： Shuyi Li Hongchao Hu XiaohanYang Guozhen Cheng Wenyan Liu Wei Guo National digital Switching System Engineering&Technological r&d center The PLA Information Engineering UniversityZhengzhou450000China

Adversarial distillation(Ad)has emerged as a potential solution to tackle the challenging optimization problem of loss with hard labels in adversarial training.However,fixed sample-agnostic and student-egocentric attack strategies are unsuitable for distillation.Additionally,the reliability of guidance from static teachers diminishes as target models become more robust.This paper proposes an Ad method called Learnable distillation Attack Strategies and Evolvable Teachers Adversarial distillation(LdAS&ET-Ad).Firstly,a learnable distillation attack strategies generating mechanism is developed to automatically generate sample-dependent attack strategies tailored for distillation.A strategy model is introduced to produce attack strategies that enable adversarial examples(AEs)to be created in areas where the target model significantly diverges from the teachers by competing with the target model in minimizing or maximizing the Ad loss.Secondly,a teacher evolution strategy is introduced to enhance the reliability and effectiveness of knowledge in improving the generalization performance of the target model.By calculating the experimentally updated target model’s validation performance on both clean samples and AEs,the impact of distillation from each training sample and AE on the target model’s generalization and robustness abilities is assessed to serve as feedback to fine-tune standard and robust teachers accordingly.Experiments evaluate the performance of LdAS&ET-Ad against different adversarial attacks on the CIFAr-10 and CIFAr-100 datasets.The experimental results demonstrate that the proposed method achieves a robust precision of 45.39%and 42.63%against AutoAttack(AA)on the CIFAr-10 dataset for resNet-18 and MobileNet-V2,respectively,marking an improvement of 2.31%and 3.49%over the baseline method.In comparison to state-of-the-art adversarial defense techniques,our method surpasses Introspective Adversarial distillation,the top-performing method in terms of robustness under AA attack for the CIFAr-10 dataset,with

关键词： Adversarial training adversarial distillation learnable distillation attack strategies teacher evolution strategy

Cu_2O-based solar cells using oxide semiconductors

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Journal of Semiconductors 2016年第1期37卷 38-46页

作者： Tadatsugu Minami Yuki Nishi Toshihiro Miyata Optoelectronic device System r&d center Kanazawa Institute of Technology

We describe significant improvements of the photovoltaic properties that were achieved in Al-doped ZnO（AZO）/n-type oxide semiconductor/p-type Cu_2O heterojunction solar cells fabricated using p-type Cu_2O sheets prepared by thermally oxidizing Cu sheets. The multicomponent oxide thin film used as the n-type semiconductor layer was prepared with various chemical compositions on non-intentionally heated Cu_2O sheets under various deposition conditions using a pulsed laser deposition method. In Cu_2O-based heterojunction solar cells fabricated using various ternary compounds as the n-type oxide thin-film layer, the best photovoltaic performance was obtained with an n-ZnGa_2O_4 thin-film layer. In most of the Cu_2O-based heterojunction solar cells using multicomponent oxides composed of combinations of various binary compounds, the obtained photovoltaic properties changed gradually as the chemical composition was varied. However, with the ZnO–MgO and Ga_2O_3–Al_2O_3systems, higher conversion efficiencies（á/ as well as a high open circuit voltage（Voc/ were obtained by using a relatively small amount of MgO or Al_2O_3, e.g.,（ZnO）0：91–（MgO）0：09 and（Ga_2O_3/0：975–（Al_2O_3/0：025, respectively. When Cu_2O-based heterojunction solar cells were fabricated using Al_2O_3–Ga_2O_3–MgO–ZnO（AGMZO）multicomponent oxide thin films deposited with metal atomic ratios of 10, 60, 10 and 20 at.% for the Al, Ga, Mg and Zn, respectively, a high Vocof 0.98 V and an á of 4.82% were obtained. In addition, an enhanced á and an improved fill factor could be achieved in AZO/n-type multicomponent oxide/p-type Cu_2O heterojunction solar cells fabricated using Na-doped Cu_2O（Cu_2O：Na） sheets that featured a resistivity controlled by optimizing the post-annealing temperature and duration. Consequently, an á of 6.25% and a Vocof 0.84 V were obtained in a Mg F2/AZO/n-（Ga_2O_3–Al_2O_3//p-Cu_2O：Na heterojunction solar cell fabricated using a Cu_2O：Na sheet with a resistivity of approximately 10 cm and a（Ga_（0：975）A_（l0：025）/2O3 thin film with a thickness

关键词： Cu2O n-type oxide semiconductor heterojunction solar cells high efficiency

A TSK Fuzzy Approach to Channel Estimation for OFdM Systems

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Journal of Electronic Science and Technology of China 2006年第2期4卷 101-105,109页

作者：张剑贺知明汪学刚罗家亮 SchoolofElectronic Engineering UniversityofElectronic Science and Technology ofChina Chengdu 610054 China UTStarcom Telecom r＆d center shenzhen 518057 China

This paper proposes a TSK fuzzy approach to channel estimation for Orthogonal Frequency division Multiplexing （OFdM） systems. The information of dispersive fading channel is described by using TSK fuzzy model, which is updated by the pilot symbols. The proposed approach can trace the variation of channel and it is computationally simple. Its performance is tested via simulations. results show that it is comparable to that of ideal Minimum Mean-Square-Error （MMSE） method, especially at the low Signal to Noise ratio （SNr）.

关键词： orthogonal frequency division multiplexing TSK fuzzy model robust channel estimation

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锌负极和锂负极在不同温度下的电化学行为

Science Bulletin 2023年第10期68卷 998-1007,M0003页

作者：李清洪虎郭寻朱家雄侯越刘超汪冬红梁国进赵玉伟陈奥李洪飞董斌斌李宝华支春义 department of Materials Science and Engineering City University of Hong KongHong KongChina Songshan Lake Materials Laboratory Dongguan 523808China Hong Kong center for Cerebro-Cardiovascular Health Engineering(COCHE) Hong KongChina National Engineering research center for Advanced Polymer Processing Technology Zhengzhou UniversityZhengzhou 450002China shenzhen Key Laboratory on Power Battery Safety and shenzhen Geim Graphene center Tsinghua Shenzhen International Graduate SchoolShenzhen 518055China Hong Kong Institute for Advanced Study City University of Hong KongHong KongChina

本文研究表明锂金属负极的枝晶问题在较低温度下会加剧,在较高温度下会受到抑制;而对于水系可充电锌基电池中锌金属负极的枝晶演变,温度的影响则恰恰相反.对两种负极的电化学行为的研究结果表明,界面反应速率和离子扩散率的匹配程度以... 详细信息

本文研究表明锂金属负极的枝晶问题在较低温度下会加剧,在较高温度下会受到抑制;而对于水系可充电锌基电池中锌金属负极的枝晶演变,温度的影响则恰恰相反.对两种负极的电化学行为的研究结果表明,界面反应速率和离子扩散率的匹配程度以及副反应综合影响了金属负极的枝晶生长和循环寿命.研究发现有机电解质和水电解质在上述影响因素上的不同性质导致相反的温度影响.本文进一步对混合电解质(有机和水性)进行了详细研究,以调节离子扩散率和副反应,同时扩大水系可充锌基电池的工作温度窗口.本文揭示了有机锂金属负极和水系锌基电池完全相反的温度影响,并揭示了潜在的影响机制,有助于加深对金属负极的理解,从而促进水系锌基电池的大规模应用.

关键词： Zndendrites Metalanodes Temperaturedependence Hybrid electrolytes

research of Arc Chamber Optimization Techniques Based on Flow Field and Arc Joint Simulation

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Plasma Science and Technology 2016年第3期18卷 319-324页

作者：钟建英郭煜敬张豪 r&d center Pinggao Group Co.Ltd.

The preliminary design of an arc chamber in the 550 kV SF6 circuit breaker was proposed in accordance with the technicai requirements and design experience. The structural optimization was carried out according to the no-load flow field simulation results and verified by no-load pressure measurement. Based on load simulation results such as temperature field variation at the arc area and the tendency of post arc current under different recovery voltage, the second optimal design was completed and its correctness was certificated by a breaking test. results demonstrate that the interrupting capacity of an arc chamber can be evaluated by the comparison of the gas medium recovery speed and post arc current growth rate.

关键词： flow filed arc simulation high voltage SF6 circuit breaker post arc current