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Investigation of the Anisotropic Morphology-Induced Effects of the Slippery Zone in Pitchers of Nepenthes alata

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Journal of Bionic Engineering 2015年第1期12卷 79-87页

作者： Pengfei Zhang Huawei Chen Deyuan Zhang School of Mechanical Engineering and Automation Beihang University Beijing 100191 China

Plant of carnivorous genus Nepenthes alata has evolved specific pitchers to prey insects for survival in the barren habitat, especially its slippery zone. The excellent slippery function has received considerable interest because of its potential applica- tion in antifriction surface design. The surface morphologies of intact and de-waxed slippery zones were characterized using scanning electron microscope and scanning white-light interferometer. Hierarchical structures with anisotropic micro- lunate structure and nano- wax crystals were found on the slippery zone. Due to the hierarchical structures, the slippery zone is hy- drophobic. It shows a significant anisotropic wettability with static contact angles 153.3° and 140.1° in the directions perpen- dicular and parallel to the upward direction （toward the peristome）, respectively. The sliding angles are -3° and -10° in the downward and upward directions, respectively. Crawling experiments indicate that the microscopic surface roughness and the brittleness of the wax crystals may reduce insect attachment in different modes according to the insect mass differences. Moreover, artificial slippery surfaces inspired by the slippery zone of Nepenthes alata were fabricated. Traction experiments quantitatively verified that the friction force of replicated lunate structures with Ra-2.54 μm surface roughness was reduced by about 25% as compared to flat surface with Ra-0.56 μm surface roughness for cricket claws.

关键词： biomimetic surface anisotropic wettability antifriction slippery surface Nepenthes alata

Sdr4 dominates pre-harvest sprouting and facilitates adaptation to local climatic condition in Asian cultivated rice

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Journal of Integrative Plant Biology 2022年第6期64卷 1246-1263页

作者： Bo Zhao Hui Zhang Tianxiao Chen Ling Ding Liying Zhang Xiali Ding Jun Zhang Qian Qian Yong Xiang shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China Shanxi Key Laboratory of Minor Crop Germplasm Innovation and Molecular Breeding College of Life SciencesShanxi Agricultural UniversityTaigu 030801China State Key Laboratory of Rice Biology China National Rice Research InstituteHangzhou 310006China

Pre-harvest sprouting(PHS),which reduces grain yield and quality,is controlled by seed dormancy *** few dormancy-related genes have been cloned,the genetic basis of seed dormancy in rice(Oryza sativa L.)remains ***,we performed a genome-wide association study and linkage mapping to dissect the genetic basis of seed dormancy in *** findings suggest that Seed Dormancy4(Sdr4),a central modulator of seed dormancy,integrates the abscisic acid and gibberellic acid signaling pathways at the transcriptional *** analysis revealed that three Sdr4 alleles in rice cultivars already existed in ancestral Oryza rufipogon ***,like the semi-dwarf 1(SD1)and Rc loci,Sdr4 underwent selection during the domestication and improvement of Asian cultivated *** distribution frequency of the Sdr4-n allele in different locations in Asia is negatively associated with local annual temperature and ***,we developed functional molecular markers for Sdr4,SD1,and Rc for use in molecular *** results provide clues about the molecular basis of Sdr4-regulated seed ***,these findings provide guidance for utilizing the favorable alleles of Sdr4 and Rc to synergistically boost PHS resistance,yield,and quality in modern rice varieties.

关键词： climatic adaptation pre-harvest sprouting Rc rice SD1 Sdr4 seed dormancy

Control of polymorphism in solution-processed organic thin film transistors by self-assembled monolayers

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Science China Chemistry 2020年第9期63卷 1221-1229页

作者： Danqing Liu Xu Xiao Zikai He Jingjuan Tan Lei Wang Bowen Shan Qian Miao shenzhen Key Laboratory of Polymer Science and Technology College of Materials Science and EngineeringShenzhen UniversityShenzhen 518060China Harbin Institute of Technology ShenzhenHIT Campus of University TownShenzhen 518055China Department of Chemistry the Chinese University of Hong KongShatinNew TerritoriesHong KongChina

Polymorphism of organic semiconductor films is of key importance for the performance of organic thin film transistors(OTFTs).Herein,we demonstrate that the polymorphism of solution-processed organic semiconductors in thin film transistors can be controlled by finely tuning the surface nanostructures of substrates with self-assembled monolayers(SAMs).It is found that the SAMs of 12-cyclohexyldodecylphosphonic acid(CDPA)and 12-phenyldodecylphosphonic acid(Ph DPA)induce different polymorphs in the dip-coated films of 2-dodecyl[1]benzothieno[3,2-b][1]benzothiophene(BTBT-C12).The film of BTBT-C12 on CDPA exhibits field effect mobility as high as 28.1 cm2 V-1 s-1 for holes,which is higher than that of BTBT-C12 on Ph DPA by three *** high mobility of BTBT-C12 on CDPA is attributable to the highly oriented films of BTBT-C12 with a reduced in-plane lattice and high molecular alignment.

关键词： self-assembled monolayer organic thin film transistor polymorphism interface engineering

Direct demonstration of triplet excimer in purely organic room temperature phosphorescence through rational molecular design

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Light(Science & Applications) 2022年第6期11卷 1218-1226页

作者： Zhenjiang Liu Yu Tian Jie Yang Aisen Li Yunsheng Wang Jia Ren Manman Fang Ben Zhong Tang Zhen Li Institute of Molecular Aggregation Science Tianjin UniversityTianjin 300072China Joint School of National university of Singapore Tianjin UniversityInternational Campus of Tianjin UniversityBinhai New CityFuzhou 350207China shenzhen Institute of Molecular Aggregate Science and Engineering School of Science and EngineeringThe Chinese University of Hong KongShenzhenGuangdong 518172China Tianjin Key Laboratory of Molecular Optoelectronic Sciences Department of ChemistryTianjin UniversityTianjin 300072China Department of Chemistry Wuhan UniversityWuhan 430072China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China

Organic luminogens with room temperature phosphorescence(RTP)have been paid great attention and developed rapidly for their wide application *** now,the internal mechanism and source of phosphorescence are still obscure,especially for the relationship between molecular dimer and RTP ***,we designed and synthesized eight phenothiazine 5,5-dioxide derivatives to directly reveal how the monomer and dimer in packing affect the RTP *** with strongπ-πstacking(θ<20.66°;d<3.86A)lead to pure triplet excimer emission,while those with weakπ-πstacking(27.02°<θ<40.64°;3.84A

关键词： RTP excimer rational

The Elongation Performance of Spirulina-templated Silver Micro Springs Embedded in the Polydimethylsiloxane

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Journal of Bionic Engineering 2017年第4期14卷 631-639页

作者： Jun Cai Yingying Shi Xinghao Li Deyuan Zhang School of Mechanical Engineering and Automation Beihang University Beijing 100191 China

Helical conductive particles have attracted much attention in preparing stretchable conductive materials because of their structural flexibility and uniform strain distribution under deformation. In this paper, Spirulina-templated silver micro springs were fabricated using electroless deposition of silver onto Spirulina surface. To investigate their potential application as con- ductive fillers for stretchable materials, they were mixed into polydimethylsiloxane （PDMS） uniformly, and then the mixture was spin coated on a polyfluortetraethylene （PTFE） plate to form a thin film, during which, micro springs tended to align its major axis along the radial direction of the plate. The tensile tests of micro springs were carried out using the film along the alignment direction of micro springs on the custom-made setup. Under the optimal condition of coating thickness of 0.67 gm, helical pitch of 29 gm and annealing temperature of 300 ~C, the average elongation of micro springs can reach up to -106.9%, which indicates that the as-prepared Spirulina-templated silver micro springs are promising flexible conductive fillers for fabricating stretchable conductive materials.

关键词： micro springs elongation electroless deposition of silver Spirulina stretchable conductive fillers

AI-assisted cell identification and optical sorting[Invited]

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Chinese Optics Letters 2023年第11期21卷 81-85页

作者：邓如平宋原杨嘉豪闵长俊张聿全袁小聪刘伟伟 Institute of Modern Optics Tianjin Key Laboratory of Micro-scale Optical Information Science and TechnologyNankai UniversityTianjin 300350China Nanophotonics Research Centre Institute of Microscale Optoelectronics&State Key Laboratory of Radio Frequency Heterogeneous IntegrationShenzhen UniversityShenzhen 518060China

Cell identification and sorting have been hot topics ***,most conventional approaches can only predict the category of a single target,and lack the ability to perform multitarget tasks to provide coordinate information of the *** limits the development of high-throughput cell screening ***,artificial intelligence(AI)systems based on deep-learning algorithms provide the possibility to extract hidden features of cells from original image ***,we demonstrate an AI-assisted multitarget processing system for cell identification and *** this system,each target cell can be swiftly and accurately identified in a mixture by extracting cell morphological features,whereafter accurate cell sorting is achieved through noninvasive manipulation by optical *** AI-assisted model shows promise in guiding the precise manipulation and intelligent detection of high-flux cells,thereby realizing semiautomatic cell research.

关键词： AI algorithm cell identification and sorting optical tweezers microfluidic chip

pH-Sensitive nanoscale materials as robust drug delivery systems for cancer therapy

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Chinese Chemical Letters 2020年第6期31卷 1345-1356,F0003页

作者： Zhaoqing Shi Qianqian Li Lin Mei School of Pharmaceutical Sciences(shenzhen) Sun Yat-sen UniversityShenzhen 518107China Tsinghua shenzhen International Graduate School.Tsinghua university Shenzhen 518055China

Cancer is one of the diseases that have the highest mortality,which threatens the human *** functions as the most widely used strategy in clinic to treat cancer,still exists urgent problems,like lacking selectivity and causing severe side *** to detailed researches on the metabolism,functions and histology of cancer tissues,many different features of cancer are uncovered,like lower pH in microenvironment,abnormal redox level in intracellular compartments and elevated expression level of several enzymes and ***,the development of smart nanoparticles that response to tumor specific microenvironment has lighted up hope for selective cancer ***,this review mainly focuses on pH-sensitive nano scale materials for anti-cancer drug *** summarized the formation progress of acidic tumor microenvironment,the mechanism of pHresponsive drug delivery system and nanomaterials that responsive to acidic pH in tumor microenvironment.

关键词： Cancer therapy Drug delivery systems Nanoparticles pH-sensitive material

Physical exercise reverses immuno-cold tumor microenvironment via inhibiting SQLE in non-small cell lung cancer

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Military Medical Research 2024年第4期 616-619页

作者： Zhi-Wen Luo Ya-Ying Sun Wei Xia Jun-Ying Xu Dong-Jing Xie Chun-Meng Jiao Ji-Ze Dong Hui Chen Ren-Wen Wan Shi-Yi Chen Jie Mei Wen-Jun Mao Department of Sports Medicine Huashan Hospital Affiliated to Fudan University Department of Sports Medicine Shanghai General Hospital Department of Critical Care Medicine the Affiliated Wuxi People's Hospital of Nanjing Medical University Department of Oncology the Affiliated Wuxi People's Hospital of Nanjing Medical University Guangdong Pharmaceutical university Institute of Acupuncture Research Institutes of Integrative MedicineFudan University Department of Cardiothoracic Surgery the Affiliated Wuxi People's Hospital of Nanjing Medical University

Dear Editor,Physical exercise has been shown to be associated with reduced cancer incidence and cancer-associated mortality[1,2],but the underlying mechanisms are *** regulation has emerged as one of the most prominent mechanisms explaining the effects of exercise on cancer[1,2].Physical exercise primarily lowers blood cholesterol and triglycerides,and protects against cardiovascular diseases[3].

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One-year status of hepatic venous pressure gradient measurement from 85 hospitals in China

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Portal Hypertension & Cirrhosis 2024年第2期3卷 116-123页

作者： Jitao Wang Ting Cui Linpeng Zhang Zhiping Yan Lei Li Jinjun Chen Junhui Sun Hua Xiang He Zhu Hao Wu Jiancuo Gengzang Feng Zhang Wei Wu Guohong Cao Wuhua Guo Haibin Shi Hui Xue Guangjun Huang Qiang Yu Meng Niu Huiling Xiang Derun Kong Wei Gou Xuefeng Luo Fuliang He Min Yuan Wei Liu Yong Wang Hongjie Hu Xiaoli Zhu Tao Yu Qinxue Sun Wei Qu Ting Lu Deqiang Ma Li Zhang Jun Ma Jun Yang Ketao Mu Xiaoliang Zhu Kai Xiong Huiguo Ding Shengjuan Yao Mingsheng Huang Fang Wang Zexin Wang Yong Huang Jianan Li Hongfeng Yi Birun Huang Zhongwei Zhao Duiping Feng Yanming Lei Changlong Hou Wenbo Guo Shirong Liu Gaojun Teng Kangshun Zhu Fan Wu Xiaogang Hu Wenfeng Zhang Shaoqi Yang Zhouchao Hu Pengfei Pang Shaowu Zhuang Weidong Wang Qingliang Zhu Kunpeng Zhang Chengyu Liu Dongliang Li Chao Ma Hong Jiang Xingong Zhao Weixin Ren Zhiwei Wang Lei Yu Fuhuang Lin Chaoguang Yan Feng Wang Lei Yu Hui Huan Wenyong Shen Shaofei He Chengda Zhang Jinlun Bao Jiangtao Liu Jun Wu Jianbo Zhao Jian Zhang Xiaolong Qi Hebei Provincial Key Laboratory of Cirrhosis&Portal Hypertension Xingtai People's HospitalXingtaiHebeiChina Center of Portal Hypertension Department of RadiologyZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina Department of Interventional Therapy Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijingChina Department of Intervention Taiyuan Third People's HospitalTaiyuanShanxiChina Department of Intervention Zhongshan Hospital Affiliated to Fudan UniversityShanghaiChina Department of Interventional Medicine The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Infectious Diseases Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdongChina Hepatobiliary and Pancreatic Intervention Center The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiangChina Interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunanChina Department of Intervention Sixth People's Hospital of ShenyangShenyangLiaoningChina Department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanChina Department of Intervention The Fourth People's Hospital of Qinghai ProvinceXiningQinghaiChina Department of Gastroenterology Nanjing Drum Tower HospitalNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Radiology Shulan(Hangzhou)HospitalHangzhouZhejiangChina Department of Intervention Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxiChina Department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinanShandongChina Department of Interventional Radiology Fifth Medical Center

Aims:Surveys and research on the applications of the hepatic venous pressure gradient(HVPG)are important for understanding the current status and future development of this technology in *** article aimed to investigate the status of hepatic venous pressure gradient measurement in China in ***:We investigated the overall status of HVPG technology in China-including hospital distribution,hospital level,annual number of cases,catheters used,average cost,indications,and current challenges by using online *** counting the number and percentages of cases of these results,we hope to clarify the current status of HVPG measurements in ***:According to the survey,85 hospitals in China used HVPG technology in 2022 distributed across 29 provinces.A total of 4989 HVPG measurements were performed in all of the surveyed hospitals in 2022,of which 2813 cases(56.4%)were measured *** average cost of HVPG measurement was 5646.8±2327.9 *** the clinical teams who performed the measurements(sometimes multiple per hospital),94.3%(82/87)used the balloon method,and the majority of the teams(72.4%,63/87)used embolectomy ***:This survey clarified the clinical application status of HVPG in China and confirmed that some medical institutions in China have established a foundation for this *** is still necessary to continue promoting and popularizing this technology in the future.

关键词： application status hepatic vein pressure gradient questionnaire survey