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Journal of Materials Science & Technology 2019年第2期35卷 336-343页

作者： Jinkai Zhang Wenhui Zhou Hui Wang Kaili Lin Fengshan Chen Department of orthodontics School & Hospital of Stomatology Tongji University Shanghai Engineering Research Center of Tooth Restoration and Regeneration Department of Oral & Cranio-Maxillofacial Surgery Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai Key Laboratory of Stomatology Shanghai Research Institute of Stomatology

Three-dimensional-printed(3 D-P) titanium implants display many advantages, such as design flexibility,higher efficiency, the capability to easily construct complex or customized structures, etc., and is believed to potentially replace traditional implants. However, the biological performance of the 3 D-P titanium surface has not been investigated systematically. Herein, we analyzed the surface characteristics of 3 D-P Ti6 Al4 V implants and evaluated the biological responses of bone marrow derived mesenchymal stromal cells(BMSCs) to the 3 D-P surface in vitro. Moreover, after implantation into the rat femoral condyle for3 and 6 weeks, the osseointegration performance was evaluated. The results showed the 3 D-P Ti6 Al4 V implant presented distinct fluctuant macroscale rough surface and relatively better hydrophilicity which enhanced the adhesion, proliferation, osteogenic differentiation and angiogenetic factor expression of BMSCs. Moreover, the in vivo osseointegration performance was also better than that of the control group at the early stage. The present study suggested the 3 D-P titanium alloy is a promising candidate to be used as implant material.

关键词： Three-dimensional printing Titanium alloy BMSCs Osteogenesis Osseointegration

Functional engineering strategies of 3D printed implants for hard tissue replacement

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Regenerative Biomaterials 2023年第1期10卷 148-180页

作者： Cen Chen Bo Huang Yi Liu Fan Liu In-Seop Lee College of Life Sciences and Medicine Zhejiang Sci-Tech UniversityHangzhou 310018PR China Department of orthodontics School of StomatologyChina Medical UniversityShenyang 110002PR China Institute of Human Materials Suwon 16514Republic of Korea

Three-dimensional printing technology with the rapid development of printing materials are widely recognized as a promising way to fabricate bioartificial bone *** consideration of the disadvantages of bone substitutes,including poor mechanical properties,lack of vascularization and insufficient osteointegration,functional modification strategies can provide multiple functions and desired characteristics of printing materials,enhance their physicochemical and biological properties in bone tissue ***,this review focuses on the advances of functional engineering strategies for 3D printed biomaterials in hard tissue *** is structured as introducing 3D printing technologies,properties of printing materials(metals,ceramics and polymers)and typical functional engineering strategies utilized in the application of bone,cartilage and joint regeneration.

关键词： hard tissue replacement bone regeneration 3D printing additive manufacturing functional engineering

A Comparison between 2D and 3D Images to Study Maxillary and Mandibular Widths: A Pilot Study

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Open Journal of Stomatology 2017年第3期7卷 186-196页

作者： Ilaf Al Mawaldi Sawsan Tabbaa C. Brian Preston Mayssa Salti Department of orthodontics School of Dental Medicine SUNY at Buffalo New York USA school of orthodontics Brooks Rehabilitation College of Healthcare Jacksonville University Florida USA Department of orthodontics School of Dental Medicine SUNY at Buffalo New York USA Post-Graduate Program Department of Orthodontics School of Dental Medicine SUNY at Buffalo New York USA

The objective of this study is to compare the transverse dimensions of the jaws, obtained from traditional posteroanterior (PA) cephalometric radiographs, and with the similar respective measurements obtained by means of cone beam computed tomography (CBCT). Data of twelve subjects were selected from the clinical records of Orthodontic Department. All of the subjects had their permanent teeth in occlusion and had good quality regular (2D), and CBCT (3D) images as part of their initial records. Subjects were divided to a posterior cross-bite and non-cross bite groups. The ratio of the maxillary, to mandibular transverse widths was calculated for the sample. In subjects without dental cross-bites the average ratio of the maxillary, to mandibular jaw widths was 0.75 on the standard radiographs and 1.04 on the CBCT scans. In subjects with dental cross-bites the average ratio of these widths was 0.70 on the standard radiographs and 0.9 on the CBCT scans. The ratios of the maxillary, to mandibular widths differ when obtained from conventional cephalometric radiographs as compared to the respective ratios obtained from CBCT scans. Maxillary, to mandibular width ratio is in the order of 1:1 as determined by means of CBCT scans.

关键词： Posteroanterior Cephalometric (PA) Radiograph CBCT 2D 3D Transverse Jaw Measurements Posterior Cross-Bite

STEINER CEPHALOMETRIC NORMS FOR SHANGHAI ADULT

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Medical Bulletin of Shanghai Jiaotong University 1991年第2期14卷 94-98页

作者：彭适生 Department of orthodontics School of Stomatology SSMU Shanghai

In this paper, 60 samples (30 male and 30 female) with normal occlusion in permanent dentition were selected. 60 lateral radiographic cephalograms were taken. By mean of Steiner analysis, means, standard deviations were calculated. Acceptable compromises for individual use were established. Comparison these data with Beijing and Korean were made. Thus the characteristics of craniofacial morphology and denture patterns of Shanghai adult were observed.

关键词： Steiner analysis cephalometric acceptable compromises

EFFECT OF PULSED ELECTROMAGNETIC FIELD AND BIOMECHANICAL FORCE ON ORTHODONTIC TOOTH MOVEMENT

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Medical Bulletin of Shanghai Jiaotong University 1991年第2期14卷 81-85页

作者：陈青蓉楼昭华蔡中刘侃彭适生 Department of orthodontics School of Stornatology SSMU Shanghai

The purpose of this experiment is to investigate the effect of pulsed electromagnetic field (PEMF) and biomechanical force on orthodontic tooth movement by means of measurement of gross tooth movement anatomic data, light microscopic evaluation and transmission electromicroscopic evaluation. The results indicate that PEMF combined with biomechanical force could accelerate the rate and amount of orthodontic tooth movement, enhance bone deposition in tension side and resorption in compression side. The results also suggest that PEMF could accelerate orthodontic tooth movement as a result of increase in quantity of active cells, PEMF couldn’t change the ultrastructure of cells.

关键词： putsed electromagnetic field orthodontic tooth movement

Advances in orthodontic clear aligner materials

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Bioactive Materials 2023年第4期22卷 384-403页

作者： Yashodhan M.Bichu Abdulraheem Alwafi Xiaomo Liu James Andrews Bjorn Ludwig Aditi Y.Bichu Bingshuang Zou Private Practice Abu DhabiUnited Arab Emirates Department of Oral Health Science Faculty of DentistryUniversity of British ColumbiaVancouverCanada Faculty of Dentistry Department of Dental Public HealthKing Abdulaziz UniversityJeddahSaudi Arabia Department of orthodontics Peking University School and Hospital of StomatologyBeijingChina Private Practice PerthAustralia Department of orthodontics University of HomburgSaarGermany

Rapid technological improvements in biomaterials,computer-aided design(CAD)and manufacturing(CAM)have endorsed clear aligner therapy(CAT)as a mainstay of orthodontic treatment,and the materials employed for aligner fabrication play an all-important role in determining the clinical performance of clear *** narrative review has attempted to comprehensively encompass the entire gamut of materials currently used for the fabrication of clear aligners and elucidate their characteristics that are crucial in determining their performance in an oral *** developments and current protocols in aligner fabrication,features of contemporary bioactive materials,and emerging trends related to CAT are *** in aligner material chemistry and engineering possess the potential to bring about radical transformations in the therapeutic applications of CAT;in the absence of which,clear aligners would continue to underperform clinically,due to their inherent biomechanical ***,while innovations in aligner materials such as shape memory polymers,direct three-dimensional(3D)printed clear aligners and bioactive materials combined with clear aligner materials are essential to further advance the applications of CAT;increased awareness of environmental responsibilities among aligner manufacturers,aligner prescribing clinicians and aligner users is essential for better alignment of our climate change goals towards a sustainable planet.

关键词： Clear aligners Bioactive materials Shape memory polymers Direct 3D printing Environment Review

Primary cilia in hard tissue development and diseases

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Frontiers of Medicine 2021年第5期15卷 657-678页

作者： Sijin Li Han Zhang Yao Sun Department of orthodontics School&Hospital of StomatologyTongji UniversityShanghai Engineering Research Center of Tooth Restoration and RegenerationShanghai 200072China Department of Implantology School&Hospital of StomatologyTongji UniversityShanghai Engineering Research Center of Tooth Restoration and RegenerationShanghai 200072China

Bone and teeth are hard *** tissue diseases have a serious effect on human survival and quality of *** cilia are protrusions on the surfaces of *** antennas,they are distributed on the membrane surfaces of almost all mammalian cell types and participate in the development of organs and the maintenance of *** in cilium-related genes result in a variety of developmental and even lethal *** with multiple ciliary gene mutations present overt changes in the skeletal system,suggesting that primary cilia are involved in hard tissue development and ***,primary cilia act as sensors of external stimuli and regulate bone ***,substances are trafficked through primary cilia by intraflagellar transport,which affects key signaling pathways during hard tissue *** this review,we summarize the roles of primary cilia in long bone development and remodeling from two perspectives:primary cilia signaling and sensory *** addition,the cilium-related diseases of hard tissue and the manifestations of mutant cilia in the skeleton and teeth are *** believe that all the findings will help with the intervention and treatment of related hard tissue genetic diseases.

关键词： primary cilia bone mechanical sensing hard tissue cilium-related bone disease tooth

Clear aligner treatment for a four-year-old patient with anterior crossbite and facial asymmetry:A case report

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World Journal of Clinical Cases 2022年第15期10卷 5088-5096页

作者： Yi-Ran Zou Zi-Qi Gan Li-Xing Zhao State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesDepartment of OrthodonticsWest China Hospital of StomatologySichuan UniversityChengdu 610041Sichuan ProvinceChina Department of orthodontics Hospital of StomatologyGuanghua School of StomatologySun Yat-sen UniversityGuangdong Provincial Key Laboratory of StomatologyGuangzhou 510055Guangdong ProvinceChina

BACKGROUND Clear aligners have been widely used to treat malocclusions from crowding,extraction cases to orthodontic-orthognathic cases,and practitioners are exploring the border of *** the first time,clear aligners were used to early intervene anterior cross-bite and facial *** SUMMARY This case report described a four-year-old child presented with anterior cross-bite and facial asymmetry associated with functional mandibular shift,who had undergone a failed treatment with conventional *** total treatment time was 18 weeks,and a stable outcome was *** The increasing need in early treatment highlights the need for clinicians to thoroughly investigate for the patient regarding clinical manifestation as well as patient *** hope that our case will be contemplated by clinicians when seeking for treatment alternatives.

关键词： Early treatment Three-dimensional diagnosis and treatment planning Anterior cross-bite Functional mandibular shift Case report

Root Resorption in Anterior Open Bite Malocclusions Due to Vertical Correction: A Radiometric Pilot Study

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Open Journal of Orthopedics 2023年第6期13卷 233-245页

作者： Suhina Kapoor David Briss Shuying Jiang Thomas J. Cangialosi Department of orthodontics Rutgers School of Dental Medicine Newark USA

Introduction: One of the most common risks of fixed orthodontic therapy is the evidence of root resorption post orthodontic treatment ranging from mild root blunting to severe root resorption of significant portions of the root structure. The etiology of apical root resorption is multifactorial but largely depends upon the type of orthodontic tooth movement and treatment duration. Study Objective: The primary aim of this study is to examine the association of external apical root resorption and vertical correction in anterior open bite malocclusions using panoramic radiographs for evaluation. Materials and Methods: Pre-treatment and post-treatment panoramic radiographs of 16 patients with anterior open bite malocclusions were scored to assess root resorption of anterior teeth (U/L 3-3). Initial and final root length and total tooth length for U/L 3-3 were measured on panoramic radiographs in Dolphin imaging. Results: Of the 24 pairs of measurements, 7 had a significant p-value (p Conclusions: A statistically significant amount of root resorption was observed, from pre-treatment to post-treatment radiographs. All mandibular anterior teeth except the mandibular right lateral incisors showed evidence of root resorption.

关键词： Open bite malocclusion External apical root resorption Open bite closure

Hyoid Bone Position as an Etiological Factor in Mandibular Divergence and Morphology

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Open Journal of Orthopedics 2022年第1期12卷 10-25页

作者： Tiffany Pei-Jou Chen Falon Rodhisky Shuying Sue Jiang Thomas J. Cangialosi Private Practice of orthodontics Manalapan NJ USA Private Practice of orthodontics Hope Mills NJ USA Rutgers school of Dental Medicine Newark NJ USA Department of orthodontics School of Dental Medicine Rutgers University Newark NJ USA

Objectives: The objective is to determine whether there are differences in the position of the hyoid bone at rest in natural head position in subjects with mandibular hyperdivergence and to evaluate whether there are differences in hyoid position and antegonial notch depth in mandibular hyperdivergent males and females. Methods and Materials: This is a retrospective cohort study involving a review of lateral cephalometric radiographs of 45 adult men and women with mandibular hyperdivergency. Hyperdivergency was determined by cephalometric ranges of: SN-GoGn as least +2 SD from normal, Y-axis, PP-GoGN, and gonial angle greater than +1SD from normal. A group of 45 normodivergent adults served as a control, with cephalometric ranges of: SN-GoGn within ±1 SD of normal, with only one measurement of the other three between +1 and +1.5 standard deviations. A custom

关键词： Hyoid Bone Mandibular Divergence Orthopedic Surgery