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Double ramification cycles with Orbifold Targets

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Acta Mathematica Sinica,English Series 2022年第8期38卷 1333-1376页

作者： Bo Hui cHEN cheng Yong DU rui WANG Department of Mathematics Sichuan UniversityChengdu 610064P.R.China school of mathematical sciences V.C.&V.R.Key Lab and Laurent Mathematics CenterSichuan Normal UniversityChengdu 610068P.R.China Department of Mathematics University of CaliforniaBerkeleyCA 94720-3840USA

In this paper,we consider double ramification cycles with orbifold *** explicit formula for double ramification cycles with orbifold targets,which is parallel to and generalizes the one known for the smooth case,is **... 详细信息

关键词： root of orbifold line bundles polynomiality double ramification cycle absolute/relative orbifold Gromov–Witten theory

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Fractal Dimension of random Attractors for Non-autonomous Fractional Stochastic Ginzburg–Landau Equations

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Acta Mathematica Sinica,English Series 2020年第3期36卷 318-336页

作者： chun Xiao GUO Ji SHU Xiao Hu WANG Department of Mathematics China University of Mining and Technology BeijingBeijing 100083P.R.China school of mathematical Science and v.c.&v.r.key lab Sichuan Normal UniversityChengdu 610068P.R.China Department of Mathematics Sichuan UniversityChengdu 610064P.R.China

This paper considers the dynamical behavior of solutions for non-autonomous stochastic fractional Ginzburg–Landau equations driven by additive noise with α∈(0, 1). First, we give some conditions for bounding the fractal dimension of a random invariant set of non-autonomous random dynamical system. Second, we derive uniform estimates of solutions and establish the existence and uniqueness of tempered pullback random attractors for the equation in H. At last, we prove the finiteness of fractal dimension of random attractors.

关键词： Non-autonomous stochastic fractional Ginzburg–Landau equation random dynamical system random attractor additive noise fractal dimension

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Probing the Gamma-ray Emission region of Five Tev Flat Spectrum radio Quasars

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research in Astronomy and Astrophysics 2024年第6期24卷 156-169页

作者： Hu-Bing Xiao Hai-Tao cao rui Xue Jin-Ting cai Ge-Ge Wang Marina Manganaro Shao-Hua Zhang Zhi-Hao Ouyang Li-Ping Fu Jun-Hui Fan Shanghai key lab for Astrophysics Shanghai Normal UniversityShanghai 200234China school of Information Engineering Guangzhou Panyu PolytechnicGuangzhou 511483China Department of Physics Zhejiang Normal UniversityJinhua 321004China college of Mathematics and Physics Guangxi Minzu UniversityNanning 530006China key laboratory of cosmology and Astrophysics(Liaoning) College of SciencesNortheastern UniversityShenyang 110819China Department of Physics University of RijekaRijeka 51000Croatia center for Astrophysics Guangzhou UniversityGuangzhou 510006China key laboratory for Astronomical Observation and Technology of Guangzhou Guangzhou 510006China Astronomy Science and Technology research laboratory of Department of Education of Guangdong province Guangzhou 510006China

The location ofγ-ray emission of blazars remains a contested topic,inspiring the development of numerous investigative techniques to address this *** this work,we analyzed Fermiγ-ray light curves in the Gev and Mev bands,employing the discrete cross-correlation function method to discern time lags between the two *** 4c+21.35,Ton 599,B21420+32,and PKS 1510-089,we identified a time lag spanning several days,while for PKS 1441+25,the time lag was not statistically *** results imply that the soft photons necessary for inverse compton scattering predominantly originate from the dusty torus in the first four sources,whereas for PKS1441+25,they seem to be sourced mainly from the broad-line *** analysis of the opacity(τγγ)and the Gev spectra study supports the conclusion that the location of the dissipation region must be beyond the BLr to avoid significant ***,for PKS 1441+25,the emission region is also posited to lie outside yet proximate to the *** parameters of describing the emission region were obtained by fitting broadband spectral energy distribution with contemporaneous observation *** findings suggest that for the five Tev FSrQs,during Te v flaring events,the jet appears to maintain an equilibrium between the energy density of the magnetic field and that of the particles for all investigated sources,with the exceptions of 4c+21.35 and PKS1441+*** terms of the overall jet power,particle energy is the dominant contributor,and the observed blazar radiation cannot be solely attributed to the magnetic field,except in the case of 4c+***,magnetic reconnection is unlikely to be the primary mechanism behind particle acceleration in these systems.

关键词： galaxies:active gamma-rays:galaxies galaxies:jets

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contactin-associated protein-like 2(cNTNAP2)mutations impair the essentialα-secretase cleavages,leading to autism-like phenotypes

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1625-1636页

作者： Qing Zhang Mengen Xing Zhengkai Bao Lu Xu Yang Bai Wanqi chen Wenhao Pan Fang cai Qunxian Wang Shipeng Guo Jing Zhang Zhe Wang Yili Wu Yun Zhang Jia-Da Li Weihong Song Oujiang laboratory(Zhejiang lab for regenerative Medicine Vision and Brain Health)Zhejiang Key Laboratory of Alzheimer's DiseaseZhejiang Provincial Clinical Research Center for Mental DisordersSchool of Mental Health and Wenzhou Kangning HospitalThe Second Affiliated Hospital and Yuying Children's HospitalInstitute of AgingWenzhou Medical UniversityWenzhouZhejiang 325035China Townsend Family laboratories Department of PsychiatryBrain Research CenterThe University of British Columbia2255 Wesbrook MallVancouverBC V6T 1Z3Canada chongqing key laboratory of Translational Medical research in cognitive Development and Learning and Memory Disorders Ministry of Education Key Laboratory of Child Development and DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China center for Medical Genetics Hunan Key Laboratory of Animal Models for Human DiseasesHunan Key Laboratory of Medical GeneticsHunan International Scientific and Technological Cooperation Base of Animal Models for Human DiseasesSchool of Life SciencesCentral South UniversityChangsha 410078 HunanChina The National clinical research center for Geriatric Disease Xuanwu HospitalCapital Medical UniversityBeijing 100053Chin

Mutations in the contactin-associated protein-like 2(cNTNAP2)gene are associated with autism spectrum disorder(ASD),and ectodomain shedding of the cNTNAP2 protein plays a role in its ***,key enzymes involved in the c-terminal cleavage of cNTNAP2 remain largely unknown,and the effect of ASD-associated mutations on this process and its role in ASD pathogenesis remain *** this report we showed that cNTNAP2 undergoes sequential cleavages by furin,ADAM10/17-dependent a-secretase and presenilindependent *** identified that the cleavage sites of ADAM10 and ADAM17 in cNTNAP2 locate at its c-terminal residue I79 and L96,and the main a-cleavage product c79 by ADAM10 is required for the subsequent y-secretase cleavage to generate cNTNAP2 intracellular domain(cIcD).ASD-associated cNTNAP2 mutations impair the a-cleavage to generate c79,and the inhibition leads to ASDIlike repetitive and social behavior abnormalties in the cntnap2l1254T knock-in ***,exogenous expression of 79 improves autism-ike phenotypes in the cntnap2^(11254T) knock-in and cntnap2^(-/-)knockout *** data demonstrates that the a-secretase is essential for cNTNAP2 processing and its *** study indicates that inhibition of the cleavage by pathogenic mutations underlies ASD pathogenesis,and upregulation of its c-terminal fragments could have therapeutical potentials for ASD treatment.

关键词： NAP2 cleavage subsequent

Fractal Dimension of random Attractors for Non-autonomous Fractional Stochastic reaction-diffusion Equations

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Journal of Partial Differential Equations 2020年第4期33卷 377-394页

作者： SHU Ji BAI Qianqian HUANG Xin ZHANG Jian school of Mathematics sciences and v.c.&v.r.key lab Sichuan Normal UniversityChengdu 610068China Department of Basic courses Sichuan Vocational College of Finance and EconomicsChengdu 610101China school of mathematical sciences University of Electronic Science and Technology of ChinaChengdu 611731China

This paper deals with non-autonomous fractional stochastic reaction-diffusion equations driven by multiplicative noise with s∈(0,1).We first present some conditions for estimating the boundedness of fractal dimension of a random invariant *** we establish the existence and uniqueness of tempered pullback random ***,the finiteness of fractal dimension of the random attractors is proved.

关键词： random dynamical system random attractor fractal dimension fractional reactiondiffusion equation multiplicative noise

Electrocatalytic synthesis of c-N coupling compounds from cO_(2) and nitrogenous species

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SusMat 2024年第2期4卷 51-74页

作者： Zheng Zhang Danyang Li Yunchuan Tu Jiao Deng Huiting Bi Yongchao Yao Yan Wang Tingshuai Li Yongsong Luo Shengjun Sun Dongdong Zheng Sónia A.c.carabineiro Zhou chen Junjiang Zhu Xuping Sun Hubei key laboratory of Biomass Fibers and Eco-Dyeing&Finishing College of Chemistry and Chemical EngineeringWuhan Textile UniversityWuhanHubeiChina school of chemistry and chemical Engineering Chongqing UniversityChongqingChina i-lab Vacuum Interconnected NanotechWorkstation(Nano-X)Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhouJiangsuChina Institute of Fundamental and Frontier sciences University of Electronic Science and Technology of ChinaChengduSichuanChina college of chemistry Chemical Engineering and Materials ScienceShandong Normal UniversityJinanShandongChina LAQv-rEQUIMTE Department of ChemistryNOVA School of Science and TechnologyUniversidade NOVA de Lisboa2829-516 CaparicaPortugal college of Materials Xiamen UniversityXiamenFujianChina

The electrocatalytic synthesis of c-N coupling compounds from cO_(2) and nitrogenous species not only offers an effective avenue to achieve carbon neutral-ity and reduce environmental pollution,but also establishes a route to synthesize valuable chemicals,such as urea,amide,and *** innovative approach expands the application range and product categories beyond simple carbona-ceous species in electrocatalytic cO_(2) reduction,which is becoming a rapidly advancing *** review summarizes the research progress in electrocatalytic urea synthesis,using N_(2),NO_(2)^(-),and NO_(3)^(-)as nitrogenous species,and explores emerging trends in the electrosynthesis of amide and amine from cO_(2) and nitro-gen ***,the future opportunities in this field are highlighted,including electrosynthesis of amino acids and other compounds containing c-N bonds,anodic c-N coupling reactions beyond water oxidation,and the catalytic mechanism of corresponding *** critical review also captures the insights aimed at accelerating the development of electrochemical c-N coupling reactions,confirming the superiority of this electrochemical method over the traditional techniques.

关键词： c-N coupling cO_(2) reduction electrocatalysis nitrogenous species reaction mechanism

An all-metallic nanovesicle for hydrogen oxidation

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National Science review 2024年第06期 233-242页

作者： Juntao Zhang Lujie Jin Hao Sun Xiaozhi Liu Yujin Ji Youyong Li Wei Liu Dong Su Xuerui Liu Zhongbin Zhuang Zhiwei Hu Qi Shao Xiaoqing Huang State key laboratory of Physical chemistry of Solid Surfaces College of Chemistry and Chemical Engineering Xiamen University Innovation laboratory for sciences and Technologies of Energy Materials of Fujian province(IKKEM) key laboratory for Special Functional Materials of Ministry of Education National &Local Joint Engineering Research Center for High-efficiency Display and Lighting Technology School of Materials Science and EngineeringCollaborative Innovation Center of Nano Functional Materials and Applications Henan University Institute of Functional Nano and Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials& Devices Soochow University State key laboratory of rare Earth resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Beijing National laboratory for condensed Matter Physics Institute of Physics Chinese Academy of Sciences State key lab of Organic-Inorganic composites Beijing University of Chemical Technology Max Planck Institute for chemical Physics of Solids college of chemistry and chemical Engineering and Materials Science Soochow University

vesicle, a microscopic unit that encloses a volume with an ultrathin wall, is ubiquitous in ***, it remains a huge challenge to create its inorganic metal-based artificial counterparts. Here,inspired by the formation of biological vesicles, we proposed a novel biomimetic strategy of curling the ultrathin nanosheets into nanovesicles, which was driven by the interfacial strain. Trapped by the interfacial strain between the initially formed substrate rh layer and subsequently formed rhru overlayer, the nanosheet begins to deform in order to release a certain amount of strain. Density functional theory（DFT）calculations reveal that the ru atoms make the curling of nanosheets more favorable in thermodynamics applications. Owing to the unique vesicular structure, the rhru nanovesicles/c displays excellent hydrogen oxidation reaction（HOr） activity and stability, which has been proven by both experiments and DFT calculations. Specifically, the HOr mass activity of rhru nanovesicles/c are 7.52 A mg（rh+ru）-1at an overpotential of 50 m v at the rotating disk electrode（rDE） level; this is 24.19 times that of commercial Pt/c(0.31 m A mgPt-1). Moreover, the hydroxide exchange membrane fuel cell（HEMFc） with rhru nanovesicles/c displays a peak power density of 1.62 W cm-2in the H2-O2condition, much better than that of commercial Pt/c(1.18 W cm-2). This work creates a new biomimetic strategy to synthesize inorganic nanomaterials, paving a pathway for designing catalytic reactors.

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Epidemiology of liver diseases:global disease burden and forecasted research trends

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Science china Life sciences 2024年

作者： Jia Xiao Fei Wang Yuan Yuan Jinhang Gao Lu Xiao chao Yan Feifei Guo Jiajun Zhong Zhaodi che Wei Li Tian Lan Frank Tacke vijay H.Shah cui Li Hua Wang Erdan Dong Division of Gastroenterology and Hepatology Mayo Clinic Department of Health sciences National Natural Science Foundation of China Department of Oncology The First Affiliated Hospital Institute for Liver Diseases of Anhui Medical University Inflammation and Immune Mediated Diseases laboratory of Anhui province Anhui Medical University research center for cardiopulmonary rehabilitation University of Health and Rehabilitation Sciences Qingdao Hospital(Qingdao Municipal Hospital) School of Health and Life Sciences University of Health and Rehabilitation Sciences Department of cardiology and Institute of vascular Medicine Peking University Third Hospital State Key Laboratory of Vascular Homeostasis and Remodeling Peking University Department of Gastroenterology Qingdao Central Hospital University of Health and Rehabilitation Sciences Guangdong Provincial key laboratory of Tumor Interventional Diagnosis and Treatment Zhuhai Hospital Affiliated with Jinan University Division of Gastroenterology Seventh Affiliated Hospital of Sun Yat-sen University school of Biological sciences Jinan University Aier Institute of Ophthalmology Central South University lab of Gastroenterology and Hepatology West China Hospital Sichuan University clinical Medicine research Institute and Department of Metabolic and Bariatric Surgery the First Affiliated Hospital of Jinan University Faculty of Pharmaceutical sciences Toho University Department of Hepatology and Gastroenterology Charité-Universit?tsmedizin Berlin Campus Virchow-Klinikum and Campus Charité Mitte

We assessed the global incidence, mortality, and disability-adjusted life years(DALYs) associated with various liver diseases, including alcohol-related liver disease(ALD), hepatitis B/c virus infections(HBv or Hcv), liver cancer, metabolic dysfunction-associated steatotic liver disease(MASLD), and other chronic liver diseases, from the 2019 Global Burden of Disease study. Additionally, we analyzed the global trends in hepatology research and drug development. From 2000 to 2019, prevalence rates increased for ALD, MASLD and other liver diseases, while they decreased for HBv, Hcv, and liver cancer. countries with a high socio-demographic index(SDI) exhibited the lowest mortality rates and DALYs. The burden of liver diseases varied due to factors like sex and region. In nine representative countries, MASLD,along with hepatobiliary cancer, showed highest increase in funding in hepatology research. Globally, the major research categories in hepatology papers from 2000 to 2019 were cancer, pathobiology, and MASLD. The United States(U.S.) was at the forefront of hepatology research, with china gradually increasing its influence over time. Hepatologists worldwide are increasingly focusing on studying the communication between the liver and other organs, while underestimating the research on ALD. cancer, Hcv, and MASLD were the primary diseases targeted for therapeutic development in clinical trials. However, the proportion of new drugs approved for the treatment of liver diseases was relatively low among all newly approved drugs in the U.S., china, Japan, and the European Union. Notably, there were no approved drug for the treatment of ALD in the world.

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Dynamical behaviors of non-autonomous fractional FitzHugh-Nagumo system driven by additive noise in unbounded domains

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Frontiers of Mathematics in china 2021年第1期16卷 59-93页

作者： chunxiao GUO Yiju cHEN Ji SHU Xinguang YANG Department of Mathematics China University of Mining and TechnologyBeijing 100083China Department of Mathematics Sichuan UniversityChengdu 610065China school of mathematical Science Laurent Mathematics Center and V.C.&:V.R.Key LabSichuan Normal UniversityChengdu 610066China Department of Mathematics and Information Science Henan Normal UniversityXinxiang 453007China

The regularity of random attractors is considered for the non-autonomous fractional stochastic FitzHugh-Nagumo *** prove that the system has a pullback random attractor that is compact in Hs(r^(n))×L^(2)(r^(n))and attracts all tempered random sets of L^(2)(r^(n))×L^(2)(r^(n))in the topology of Hs(r^(n))×L^(2)(r^(n))with s∈(0,1).By the idea of positive and negative truncations,spectral decomposition in bounded domains,and tail estimates,we achieved the desired results.

关键词： Fractional stochastic FitzHugh-Nagumo system random attractor asymptotic compactness