检索结果-南通市图书馆

Long-term Consumption of Highland Barley Tea Promotes Healthy Aging of Skeletal Muscle

food science and Human Wellness 2024年

作者： Li Yan Chenzhipeng Nie Qingwei Zheng Mingcong Fan Waleed AL-Ansi Haifeng Qian Li Wang State Key Laboratory of food science and technology School of Food Science and Technology Jiangnan University

Highland barley tea (HBT) is made from roasted barley seeds and is abundant in β-glucan， amino acids， minerals， phenolics， and other natural active ingredients. These natural compounds found in whole grains have been shown to slow aging and positively affect skeletal muscle function. As a result， studying the effects of HBT on the skeletal muscle health of the elderly population is critical from a scientific and societal standpoint for improving their health status and reducing the medical burden on society. The antioxidant activity and the content of natural active substances were used as indicators to screen the optimal process of HBT brewing. The effects of long-term HBT consumption on aging in mice were investigated by using HBT as a substitute for drinking water in naturally aging mice for a 5-month intervention. Afterward， various factors were measured， such as basic physiological indices， inflammation， plasma metabolites， skeletal muscle function， and exercise capacity， to evaluate the effects of HBT on aging in mice. Long-term consumption of HBT reduced body and spleen weight， increased body weight percentage of skeletal muscle， and reduced plasma inflammation levels in aging mice. Metabolomic results showed increased plasma levels of the mitochondrial marker short-chain acylcarnitine and some amino acids. Additionally， there was a decrease in bile and long-chain acylcarnitine. The level of fibrosis in the gastrocnemius muscle of aging mice was suppressed， and the percentage of type I muscle fibers was increased， improving the endurance of the mice. Thus， long-term consumption of HBT may reduce body weight and increase skeletal muscle mitochondrial activity and exercise capacity in aging mice by reducing inflammation levels and alleviating mitochondrial damage.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Effects of edible whole citrus fruits on endogenous antioxidant enzymes of HepG2 cells

引用

food Quality and Safety 2022年第2期6卷 310-317页

作者：孙玉敬刘苗苗陶文扬叶兴乾孙培龙 College of food science and technology Zhejiang University of TechnologyHangzhouChina Department of food science and Nutrition School of Biosystems Engine ering and Food ScienceZhejiang UniversityHangzhouChina

The effects of eating fresh citrus fruits including two varieties of mandarins,one of sweet oranges,one of grapefruit,two of pomelo,and one of kumquat cultivated in China on endogenous antioxidant enzymes were investigated by in vitro digestion and HepG2 cells.The correlations between enzyme activity and cell uptake of phytochemicals and cellular antioxidant capacities were analyzed.The results showed that most fresh citrus fruits increased the endogenous antioxidant activity.Bairoumiyou,Hongroumiyou,Ponkan,and Jinju after digestion significantly increased the activity of catalase(P<0.05).Hongroumiyou,Bairoumiyou,Ponkan navel orange,and Jinju after digestion significantly increased glutathione peroxidases(GPxs)activity(P<0.05),while Huyou and satsuma could not increase the activity of GPxs after digestion.Thioredoxin oxidoreductase activity was improved significantly by most of the digested whole citrus fruits except Ponkan(P<0.05)and thioredoxin oxidoreductase added whole citrus fruits had a higher increase than added citrus fruits extracts.The results indicated that edible whole citrus fruits had similar effects as extracts on enzymes.

关键词： Citrus fruit endogenous antioxidant enzymes in vitro digestion polyphenols carotenoids

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering the thermostability of D-lyxose isomerase from Caldanaerobius polysaccharolyticus via multiple computer-aided rational design for efficient synthesis of D-mannose

引用

Synthetic and Systems Biotechnology 2023年第2期8卷 323-330页

作者： Hao Wu Ming Yi Xiaoyi Wu Yating Ding Minghui Pu Li Wen Yunhui Cheng Wenli Zhang Wanmeng Mu school of food science and Bioengineering Changsha University of Science&TechnologyChangsha410114China State Key Laboratory of food science and technology Jiangnan UniversityWuxi214122China

D-Mannose is an attractive functional sugar that exhibits many physiological benefits on human health.The demand for low-calorie sugars and sweeteners in foods are increasingly available on the market.Some sugar isomerases,such as D-lyxose isomerase(D-LIase),can achieve an isomerization reaction between D-mannose and D-fructose.However,the weak thermostability of D-LIase limits its efficient conversion from D-fructose to D-mannose.Nonetheless,few studies are available that have investigated the molecular modification of D-LIase to improve its thermal stability.In this study,computer-aided tools including FireProt,PROSS,and Consensus Finder were employed to jointly design D-LIase mutants with improved thermostability for the first time.Finally,the obtained five-point mutant M5(N21G/E78P/V58Y/C119Y/K170P)showed high thermal stability and cat-alytic activity.The half-life of M5 at 65◦C was 10.22 fold,and the catalytic efficiency towards 600 g/L of D-fructose was 2.6 times to that of the wild type enzyme,respectively.Molecular dynamics simulation and intramolecular forces analysis revealed a thermostability mechanism of highly rigidity conformation,newly formed hydrogen bonds andπ-cation interaction between and within protein domains,and redistributed surface electrostatic charges for the mutant M5.This research provided a promising D-LIase mutant for the industrial production of D-mannose from D-fructose.

关键词： D-lyxose isomerase Thermostability D-mannose Molecular modification

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nondestructive determination of IMP content in chilled chicken based on hyperspectral data combined with chemometrics

引用

International Journal of Agricultural and Biological Engineering 2022年第1期15卷 277-284页

作者： Yangyang Wang Hongju He Shengqi Jiang Hanjun Ma school of food science Henan Institute of Science and TechnologyXinxiang 453003HenanChina

This study was conducted to investigate the potential of hyperspectral imaging technique(900-1700 nm)for nondestructive determination of inosinic acid(IMP)in chicken.Hyperspectral images of chicken flesh samples were acquired,and their mean spectra within the images were extracted.The quantitative relationship between the mean spectra and reference IMP value was fitted by partial least squares(PLS)regression algorithm.A PLS model(MAS-PLS)built with moving average smoothing(MAS)spectra showed better performance in predicting IMP content,leading to correlation coefficients(RP)of 0.951,root mean square error(RMSEP)of 0.046 mg/g,and residual predictive deviation(RPD)of 3.152.Regression coefficient(RC),successive projections algorithm(SPA),stepwise,competitive adaptive reweighted sampling(CARS),and uninformative variable elimination(UVE)were used to select the optimal wavelengths to optimize the MAS-PLS model.Based on the 18 optimal wavelengths(907.14,917.02,918.67,926.90,930.20,936.78,956.54,1004.28,1135.89,1211.56,1302.07,1367.94,1397.60,1488.31,1680.17,1683.49,1686.80 and 1695.10 nm)selected from MAS spectra by SPA,the MAS-SPA-PLS model was built with R_(P) of 0.920,RMSEP of 0.056 mg/g and RPD of 3.220,which was similar to the MAS-PLS model.The overall study indicated that hyperspectral imaging in the 900-1700 nm range combined with PLS and SPA could be used to predict the IMP content in chicken flesh.

关键词： near-infrared hyperspectral imaging chicken inosinic acid partial least squares successive projections algorithm

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Apigenin is an anoikis sensitizer with strong anti-metastatic properties in experimental breast cancer

引用

food science and Human Wellness 2023年

作者： Ruijie Xu Zhijie Yao Hao Zhang Haitao Li Wei Chen State Key Laboratory of food science and technology Jiangnan University School of Food Science and Technology Jiangnan University

Loss of susceptibility to anoikis signals is a crucial step in metastasis. Anoikis resistance therefore represents a promising adjuvant therapeutic target for cancer management. In this study， we have conducted a rationalized screening to search for novel leading anoikis sensitizer from daily foods. Among 19 tested dietary phytochemicals， the best results were obtained with apigenin， a natural component of celery. Phenotypically， apigenin sensitized breast cancer cells to anoikis， lowered the number of circulating tumor cells， and protected against breast cancer metastasis to lung in mice. Mechanistically， we demonstrated that the thromboxane A2(TXA2)- TXA2receptor (TP) axis has a critical role in acquired anoikis resistance by activating PI3K-Akt signaling pathway. Blockage of TXA2signaling up-regulate p53 as well as its target gene p21， caused a G1 phase arrest， and finally led to apoptosis in breast cancer cells. TXA2level was positively correlated with breast cancer cell anoikis rate， and apigenin significantly inhibited TXA2biosynthesis in vitro and in vivo. Collectively， we identified apigenin as potent anoikis sensitizer with anti-metastatic properties in a mouse model of breast cancer， and these findings might provide a rationale for introducing apigenin supplementation to breast cancer patients.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Insight into the ammonia torrefaction and pyrolysis system of cellulose:Unraveling the evolution of chemical structure and nitrogen migration mechanism

引用

Journal of Energy Chemistry 2023年第3期78卷 135-147,I0005页

作者： Shanjian Liu An Zhao Jia Liu Mengqian Yin Fupeng Huang Dongmei Bi school of Agricultural Engineering and food science Shandong University of TechnologyZibo 255000ShandongChina

This study aimed to investigate the mechanism of nitrogen doping,migration,and conversion during ammonia torrefaction and also explore the evolution law of the chemical structure of cellulose.The results showed that the ammonia torrefaction pretreatment could significantly optimize the distribution of nitrogen and oxygen elements in cellulose.The carbon skeleton first captured the active nitrogenous radicals to form-NHn-N,and pyridine-N and pyrrole-N originated from the conversion of-NHn-N.The existence of C=O played a major role in the immobilization of nitrogen.The nitrogen in bio-oil exists mainly in the form of five-and six-membered heterocycles.The correlation analysis showed that the main precursors for the formation of nitrogenous heterocyclic compounds were five-membered Oheterocyclic compounds.Finally,the product distribution characteristics in the torrefaction-pyrolysis systems were summarized,and the nitrogen doping and conversion mechanisms were proposed.This study expanded the boundaries of cellulose pretreatment and the production of high-value chemicals.

关键词： Ammonia torrefaction Cellulose Nitrogenous compounds Structure evolution Nitrogen migration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microbiomics and metabolomics insights into the microbial regulation on the formation of flavor components in the traditional fermentation process of Chinese Hongqu aged vinegar

引用

food science and Human Wellness 2023年

作者： Shan-Gong Tong Wen-Long Li Yuan-Dong Rao Yan-Qin Xiao Ying-Yin Yan Wei-Ling Guo Xu-Cong Lv Jin-Yuan Sun Lian-Zhong Ai Li Ni Institute of food science and technology College of Biological science and Engineering Fuzhou University School of Food Science and Technology Jiangnan University Beijing Laboratory for food Quality and Safety Beijing technology and Business University school of Health science and Engineering University of Shanghai for science and technology food Nutrition and Health Research Center school of Advanced Manufacturing Fuzhou University

This study aimed to investigate microbial succession and metabolic dynamics during the traditional fermentation of Hongqu aged vinegar， and explore the core functional microbes closely related to the formation of flavor components. Microbiome analysis demonstrated that Lactobacillus， Acetobacter， Bacillus， Enterobacter， Lactococcus， Leuconostoc and Weissella were the predominant bacterial genera， while Aspergillus piperis， Aspergillus oryzae， Monascus purpureus， Candida athensensis， Candida xylopsoci， Penicillium ochrosalmoneum and Simplicillium aogashimaense were the predominant fungal species. Correlation analysis revealed that Acetobacter was positively correlated with the production of tetramethylpyrazine， acetoin and acetic acid， Lactococcus showed positive correlation with the production of 2-nonanone， 2-heptanone， ethyl caprylate， ethyl caprate， 1-hexanol， 1-octanol and 1-octen-3-ol， Candida xylopsoci and Candida rugosa were positively associated with the production of diethyl malonate， 2，3-butanediyl diacetate， acetoin， benzaldehyde and tetramethylpyrazine. Correspondingly， non-volatile metabolites were also detected through UPLC-QTOF/MS. A variety of amino acids and functional dipeptides were identified during the traditional brewing of Hongqu aged vinegar. Correlation analysis revealed that Lactobacillus was significantly associated with DL-lactate， indolelactic acid， D-(+)-3-phenyllactic acid， pimelic acid， pregabalin and 3-aminobutanoic acid. This study is useful for understanding flavor formation mechanism and developing effective strategies for the suitable strains selection to improve the flavor quality of Hongqu aged vinegar.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The impact of the novel starch-lipid complexes on the glucolipids metabolism， inflammation， and gut dysbiosis of Type 2 diabetes mellitus rats

引用

food science and Human Wellness 2023年

作者： Yingshuang Lu Renbing Qin Jin Wang Fengjuan Xiang Yan Zhang Bowei Zhang Dancai Fan Huan Lv Xuemeng Ji Shujun Wang Shuo Wang State Key Laboratory of food Nutrition and Safety Tianjin University of science & technology school of food science Henan Institute of science and technology Tianjin Key Laboratory of food science and Health school of Medicine Nankai University

It has been widely accepted that resistant starch (RS) provides numerous health benefits for human. In this research， we aimed at evaluating the performance of novel starch-lipid complexes， RS5， in comparison with RS2 on physical features， glucolipids metabolism， inflammation， and gut microbiota profiles of Type 2 diabetes mellitus (T2DM) rats. The T2DM model was established by streptozotocin injection to the high-fat-sugar fed rats. According to a serial of biochemical analyses， we found that RS5 diets were strongly correlated with enhanced homeostatic model assessment for insulin secretion (HOMA-IS)， high-density lipoprotein cholesterol (HDL-C)， adiponectin (ADP)， insulin action index (IAI)， glucagon-like peptide-1 (GLP1)， and short-chain fatty acids (SCFAs) in T2DM rats whilst negatively associated with the low-density lipoprotein (LDL-C) and inflammatory cytokines， showing the capabilities to ameliorate T2DM symptoms by regulation of glucolipid metabolism， gut metabolites， and inflammation. On the other hand， RS2-enriched supplementations were influential in the mediation of insulin secretion to improve glucose metabolism. The increasing evidence collected herein suggested that intestinal microbiota could mediate glucolipids metabolism and alleviate inflammation after certain microflora nourished by RS. In addition， RS intake made an impact on PI3K/AKT signaling pathway that might contribute to the improvement of glucose metabolism， insulin resistance， and inflammatory responses.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Gold-nanoparticle-based multiplex immuno-strip biosensor for simultaneous determination of 83 antibiotics

引用

Nano Research 2023年第1期16卷 1259-1268页

作者： Xianlu Lei Xinxin Xu Liqiang Liu Liguang Xu Li Wang Hua Kuang Chuanlai Xu State Key Laboratory of food science and technology Jiangnan UniversityWuxi 214122China International Joint Research Laboratory for Biointerface and Biodetection and School of Food Science and TechnologyJiangnan UniversityWuxi 214122China

Antibiotic residues,generated by the irrational use of drugs and environmental pollution,have always been a great challenge to aquaculture safety.Therefore,a quick,convenient,and performance-excellent way to detect antibiotic residues in aquaculture fish is urgently required.In this study,a multiplex immunochromatographic strip biosensor based on gold nanoparticles was developed for the simultaneous detection of five classes of antibiotic residues(24β-lactam antibiotics,26 sulfonamides,five tetracyclines,24 quinolones,and four amphenicols)in aquaculture fish within 10 min.The detection ranges of five representative antibiotics,penicillin G,sulfamethazine,tetracycline,enrofloxacin,and chloramphenicol,were 2.33–38.4,0.688–17.1,1.4–48.1,1.45–32.9,and 0.537–9.06μg/kg,respectively.The accuracy and stability of these measurements were demonstrated by analyzing spiked fish samples,with recovery rates of 87.5%–115.2%and a coefficient of variation<9.5%.The cross-reaction rates,based on the five representative antibiotics,were 3.77%–202%forβ-lactams,3.95%–137%for sulfonamides,9.19%–100%for tetracyclines,4.9%–145%for quinolones,and 3.2%–100%for amphenicols.The excellent testing performance of the biosensor strip to most of antibiotic residues in aquaculture fish ensures they meet the maximum residue limits required by countries or organizations.Therefore,this multiplex immunochromatographic strip biosensor is potentially applicable to the rapidly on-site determination of antibiotic residues in aquaculture fish.

关键词： antibiotic aquaculture biosensor immunochromatographic strip

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Improvement of gelation properties of myofibrillar proteins from porcine longissimus dorsi muscle through microwave combined with air convection thawing treatment

引用

International Journal of Agricultural and Biological Engineering 2023年第3期16卷 254-261页

作者： Fenxia Han Mingming Zhu Yi Xing Hanjun Ma school of Animal science and Veterinary Medicine Henan Institute of Science and TechnologyXinxiang 453003HenanChina school of food science Henan Institute of Science and TechnologyXinxiang 453003HenanChina

The effects of the microwave combined with air convection thawing(MAT)on the gelling properties of pork myofibrillar proteins(MPs)were further studied and compared with those of fresh meat(FM),and single thawing methods(microwave thawing(MT)and air convection thawing(AT)).Results revealed that the thawing methods,excluding MAT,induced deterioration in the gelling properties of MPs.There was no significant difference(p>0.05)in the water holding capacity(WHC),cooking loss,whiteness,and strength of gel samples subjected to MAT and those of FM samples,demonstrating that the gelling properties were retained after MAT.As well,protein aggregation was limited,since MAT reduced the change in zeta potential and turbidity compared to that observed with MT or AT.The dynamic rheology and scanning electron microscopic results were relatively consistent,revealing that among the different thawing techniques,MAT had the least negative impact on the microstructure of MPs gel,leading to the generation of a more elastic and uniform gel structure than that of the MT or AT gels.Moreover,MAT resulted in higher water retention in the gels than that achieved with MT or AT.These findings indicated that MAT improved the gelling properties of MPs,thereby confirming the suitability of this treatment for use in the meat processing industry.

关键词： microwave combined with air convection thawing gelling property myofibrillar protein moisture distribution microstructure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：