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Machine-learned wearable sensors for real-time hand-motion recognition: toward practical applications

National Science Review 2024年第2期11卷 231-263页

作者： Kyung Rok Pyun Kangkyu Kwon Myung Jin Yoo Kyun Kyu Kim Dohyeon Gong Woon-Hong Yeo Seungyong Han Seung Hwan Ko Department of Mechanical engineering Seoul National University IEN center for Human-Centric Interfaces and engineering Institute for Electronics and NanotechnologyGeorgia Institute of Technology school of electrical and computer engineering Georgia Institute of Technology Department of Chemical engineering Stanford University Department of Mechanical engineering Ajou University George W.Woodruff school of Mechanical engineering Georgia Institute of Technology Institute of Advanced Machinery and Design(SNU-IAMD) Seoul National University

Soft electromechanical sensors have led to a new paradigm of electronic devices for novel motion-based wearable applications in our daily lives. However, the vast amount of random and unidentified signals generated by complex body motions has hindered the precise recognition and practical application of this technology. Recent advancements in artificial-intelligence technology have enabled significant strides in extracting features from massive and intricate data sets, thereby presenting a breakthrough in utilizing wearable sensors for practical applications. Beyond traditional machine-learning techniques for classifying simple gestures, advanced machine-learning algorithms have been developed to handle more complex and nuanced motion-based tasks with restricted training data sets. Machine-learning techniques have improved the ability to perceive, and thus machine-learned wearable soft sensors have enabled accurate and rapid human-gesture recognition, providing real-time feedback to users. This forms a crucial component of future wearable electronics, contributing to a robust human–machine interface. In this review, we provide a comprehensive summary covering materials, structures and machine-learning algorithms for hand-gesture recognition and possible practical applications through machine-learned wearable electromechanical sensors.

关键词： wearable sensor soft electronics artificial intelligence machine learning human–machine interfaces gesture recognition

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Advances in Wireless,Batteryless,Implantable Electronics for Real‑Time,Continuous Physiological Monitoring

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Nano-Micro Letters 2024年第3期16卷 254-302页

作者： Hyeonseok Kim Bruno Rigo Gabriella Wong Yoon Jae Lee Woon‑Hong Yeo IEN center for Wearable Intelligent Systems and Healthcare Georgia Institute of TechnologyAtlantaGA 30332USA George W.Woodruff school of Mechanical engineering Georgia Institute of TechnologyAtlantaGA 30332USA school of electrical and computer engineering Georgia Institute of TechnologyAtlantaGA 30332USA Wallace H.Coulter Department of Biomedical engineering Georgia Tech and Emory University School of MedicineAtlantaGA 30332USA Parker H.Petit Institute for Bioengineering and Biosciences Institute for MaterialsInstitute for Robotics and Intelligent MachinesGeorgia Institute of TechnologyAtlantaGA 30332USA

This review summarizes recent progress in developing wireless,batteryless,fully implantable biomedical devices for real-time continuous physiological signal monitoring,focusing on advancing human health care.Design considerations,such as biological constraints,energy sourcing,and wireless communication,are discussed in achieving the desired performance of the devices and enhanced interface with human tissues.In addition,we review the recent achievements in materials used for developing implantable systems,emphasizing their importance in achieving multi-functionalities,biocompatibility,and hemocompatibility.The wireless,batteryless devices offer minimally invasive device insertion to the body,enabling portable health monitoring and advanced disease diagnosis.Lastly,we summarize the most recent practical applications of advanced implantable devices for human health care,highlighting their potential for immediate commercialization and clinical uses.

关键词： Implantable electronics Biomedical systems Batteryless devices Wireless electronics Physiological signal monitoring

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基于侧基多通道和对称性破缺效应的分子电导调控

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Science China Materials 2024年第6期67卷 1994-1999页

作者：郝杰汪博宇赵璁霍雅妮王进莹贾传成郭雪峰 center of Single-Molecule Sciences Institute of Modern OpticsFrontiers Science Center for New Organic MatterTianjin Key Laboratory of Micro-scale Optical Information Science and TechnologyCollege of Electronic Information and Optical EngineeringNankai UniversityTianjin 300350China Network for Computational nanotechnology School of Electrical and Computer EngineeringPurdue UniversityIndiana 47907USA Beijing National Laboratory for Molecular Sciences National Biomedical Imaging CenterCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

化学取代是有效调节分子电导,产生多通道输运、量子干涉效应和其他机制的关键方法.但分子骨架和侧基之间存在复杂的相互作用,目前仍未被研究清楚.在本工作中,我们结合扫描隧道显微镜裂结实验技术和第一性原理计算方法,深入研究了具有不... 详细信息

化学取代是有效调节分子电导,产生多通道输运、量子干涉效应和其他机制的关键方法.但分子骨架和侧基之间存在复杂的相互作用,目前仍未被研究清楚.在本工作中,我们结合扫描隧道显微镜裂结实验技术和第一性原理计算方法,深入研究了具有不同σ和π侧基的分子电导.实验结果及理论分析表明,σ侧基的加入引起了分子前线轨道的对称性破缺并加剧了分子内散射,从而导致电导的降低.相反,π侧基引入了额外的电荷传输通道,实现了电荷传输的多通道效应,增加了分子的电导.这些发现为未来分子功能化和分子电子器件的设计提供了坚实的基础.

关键词： side substituent multiple-channel effect symmetry-breaking effect single-molecule junction

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Electronic properties of 2D materials and their junctions

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Nano Materials Science 2024年第1期6卷 1-23页

作者： Taposhree Dutta Neha Yadav Yongling Wu Gary J.Cheng Xiu Liang Seeram Ramakrishna Aoussaj Sbai Rajeev Gupta Aniruddha Mondal Zheng Hongyu Ashish Yadav Department of Chemistry Indian Institute of Engineering Science and TechnologyShibpurWest Bengal711103India center for Advanced Laser Manufacturing(CALM) Shandong University of TechnologyZibo255000PR China school of Industrial engineering Purdue University315 N.Grant St.West LafayetteIN47907United States birck nanotechnology center Purdue University1205 W State St.West LafayetteIN47907United States Advanced Materials Institute Qilu University of TechnologyShandong Academy of SciencesJinan250014PR China Nanoscience and nanotechnology Initiative National University of Singapore10 Kent Ridge Crescent119260Singapore Faculty of Applied Phsyics and Mathematics Gdansk University of Technology Narutowicza 11/1280233GdanskPoland Department of Physics School of EngineeringUniversity of Petroleum&Energy StudiesDehradun248007UttarakhandIndia Department of Physics National Institute of Technology DurgapurDurgapur713209West BengalIndia

With an extensive range of distinctive features at nano meter-scale thicknesses,two-dimensional(2D)materials drawn the attention of the scientific community.Despite tremendous advancements in exploratory research on 2D materials,knowledge of 2D electrical transport and carrier dynamics still in its infancy.Thus,here we highlighted the electrical characteristics of 2D materials with electronic band structure,electronic transport,dielectric constant,carriers mobility.The atomic thinness of 2D materials makes substantially scaled field-effect transistors(FETs)with reduced short-channel effects conceivable,even though strong carrier mobility required for high performance,low-voltage device operations.We also discussed here about factors affecting 2D materials which easily enhanced the activity of those materials for various applications.Presently,Those 2D materials used in state-of-the-art electrical and optoelectronic devices because of the extensive nature of their electronic band structure.2D materials offer unprecedented freedom for the design of novel p-n junction device topologies in contrast to conventional bulk semiconductors.We also,describe the numerous 2D p-n junctions,such as homo junction and hetero junction including mixed dimensional junctions.Finally,we talked about the problems and potential for the future.

关键词： 2D materials electrical properties p-n junctions Mixed hereto junctions Homo junctions electrical transport

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Integrated proteomic profiling identifies amino acids selectively cytotoxic to pancreatic cancer cells

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The Innovation 2024年第3期5卷 138-145页

作者： Alfred Akinlalu Zachariah Flaten Komila Rasuleva Md Saimon Mia Aaron Bauer Santhalingam Elamurugan Nega Ejjigu Sudipa Maity Amara Arshad Min Wu Wenjie Xia Jia Fan Ang Guo Sijo Mathew Dali Sun Department of electrical and computer engineering University of Denver2155 E Wesley AvenueDenverCO 80210USA Biomedical engineering Program North Dakota State University1401 Centennial BoulevardEngineering AdministrationRoom 203FargoND 58102USA Department of Pharmaceutical Sciences School of PharmacyNorth Dakota State University1001 S.1401 Albrecht Boulevard Sudro HallFargoND 58102USA Materials and nanotechnology Program North Dakota State University1410 North 14th AvenueCIE 201FargoND 58102USA Wenzhou Institute University of Chinese Academy of SciencesWenzhouZhejiang 325000China Department of Aerospace engineering Iowa State UniversityAmesIA 50011USA center for Cellular and Molecular Diagnostics Tulane University School of Medicine1430 Tulane AvenueNew OrleansLA 70112USA Department of Biochemistry and Molecular Biology Tulane University School of Medicine1430 Tulane AvenueNew OrleansLA 70112USA Knoebel Institute for Healthy Aging University of Denver2155 E Wesley AvenueDenverCO 80210USA

Pancreatic adenocarcinoma(PDAC)is one of the most deadly cancers,characterized by extremely limited therapeutic options and a poor prognosis,as it is often diagnosed during late disease stages.Innovative and selective treatments are urgently needed,since current therapies have limited efficacy and significant side effects.Through proteomics analysis of extracellular vesicles,we discovered an imbalanced distribution of amino acids secreted by PDAC tumor cells.Our findings revealed that PDAC cells preferentially excrete proteins with certain preferential amino acids,including isoleucine and histidine,via extracellular vesicles.These amino acids are associated with disease progression and can be targeted to elicit selective toxicity to PDAC tumor cells.Both in vitro and in vivo experiments demonstrated that supplementation with these specific amino acids effectively eradicated PDAC cells.Mechanistically,we also identified XRN1 as a potential target for these amino acids.The high selectivity of this treatment method allows for specific targeting of tumor metabolism with very low toxicity to normal tissues.Furthermore,we found this treatment approach is easy-to-administer and with sustained tumor-killing effects.Together,our findings reveal that exocytosed amino acids may serve as therapeutic targets for designing treatments of intractable PDAC and potentially offer alternative treatments for other types of cancers.

关键词： finding identif selectivity

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A generalized synthesis method for freestanding multiferroic twodimensional layered supercell oxide films via a sacrificial buffer layer

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Nano Research 2023年第7期16卷 10559-10566页

作者： Jianan Shen Benson Kunhung Tsai Ke Xu Anyu Shang James PBarnard Yizhi Zhang Rahul Tripathi Zhihong Chen Xinghang Zhang Haiyan Wang school of Materials engineering Purdue UniversityWest LafayetteIndiana 47907USA Elmore Family school of electrical and computer engineering Purdue UniversityWest LafayetteIndiana 47907USA birck nanotechnology center Purdue UniversityWest LafayetteIndiana 47907USA

Multiferroics are an intriguing family of materials due to the simultaneous presence of two ferroic orderings,namely,ferroelectricity and ferromagnetism.They are scientifically and technologically important and have numerous potential applications,such as four-state logic memories and multiferroic tunneling junctions.However,the growth of epitaxial singlephase multiferroic thin films typically requires single crystalline oxide substrates,which hinders their future integration with Sibased devices.In this study,we report a generalized synthesis method that uses the polydimethylsiloxane(PDMS)-assisted wetetching method with an Sr_(3)Al_(2)O_(6)(SAO)sacrificial layer to transfer freestanding single-phase multiferroic Bi_(2)NiMnO_(6)(BNMO)films from conventional SrTiO_(3)(STO)substrates onto a Si wafer.The structures and properties of the films have been characterized before and after the transfer.These transferred films possess good multiferroic properties on Si wafers,indicating full compatibility with modern Si technology.This method can be generally applicable to other Bi-based multiferroic materials as well.Lastly,the original STO substrates after the transfer process have been recycled for preparing new batches of freestanding BNMO films,indicating a low-cost and sustainable method for manufacturing large-volume freestanding complex oxide thin films.

关键词： multiferroics freestanding films wet-transfer SAO sacrificial layer recyclable substrates sustainable

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Symmetry breaking in thermal photonics

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Light(Science & Applications) 2022年第12期11卷 2835-2836页

作者： Xueji Wang Zubin Jacob birck nanotechnology center Elmore Family School of Electrical and Computer EngineeringPurdue UniversityWest LafayetteIN 47907USA

engineering symmetries in nanostructures and metasurfaces provides a new paradigm to control incoherent heat radiation for applications in energy conversion,thermal sources,infrared imaging,and radiative cooling.

关键词： thermal breaking radiative

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Ultra-thin, planar, Babinet-inverted plasmonic metalenses

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Light(Science & Applications) 2013年第1期2卷 170-175页

作者： Xingjie Ni Satoshi Ishii Alexander V Kildishev Vladimir M Shalaev school of electrical and computer engineering and birck nanotechnology center Purdue UniversityWest LafayetteIN 47907USA

We experimentally demonstrate the focusing of visible light with ultra-thin,planar metasurfaces made of concentrically perforated,30-nm-thick gold films.The perforated nano-voids—Babinet-inverted(complementary)nano-antennas—create discrete phase shifts and form a desired wavefront of cross-polarized,scattered light.The signal-to-noise ratio in our complementary nano-antenna design is at least one order of magnitude higher than in previous metallic nano-antenna designs.We first study our proof-of-concept‘metalens’with extremely strong focusing ability:focusing at a distance of only 2.5 mm is achieved experimentally with a 4-mm-diameter lens for light at a wavelength of 676 nm.We then extend our work with one of these‘metalenses’and achieve a wavelength-controllable focal length.Optical characterization of the lens confirms that switching the incident wavelength from 676 to 476 nm changes the focal length from 7 to 10 mm,which opens up new opportunities for tuning and spatially separating light at different wavelengths within small,micrometer-scale areas.All the proposed designs can be embedded on-chip or at the end of an optical fiber.The designs also all work for two orthogonal,linear polarizations of incident light.

关键词： metalens nano-antennas plasmonics wavefront shaping

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Ghost resonance in anisotropic materials:negative refractive index and evanescent field enhancement in lossless media

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Advanced Photonics 2019年第4期1卷 21-31页

作者： Evgenii Narimanov Purdue University School of Electrical and Computer EngineeringBirck Nanotechnology CenterWest LafayetteIndianaUnited States

We show that dielectric waveguides formed by materials with strong optical anisotropy support electromagnetic waves that combine the properties of propagating and evanescent fields.These“ghost waves”are created in tangent bifurcations that“annihilate”pairs of positive-and negative-index modes and represent the optical analogue of the“ghost orbits”in the quantum theory of nonintegrable dynamical systems.Ghost waves can be resonantly coupled to the incident evanescent field,which then grows exponentially through the anisotropic media—as in the case of negative index materials.As ghost waves are supported by transparent dielectric media,the proposed approach to electromagnetic field enhancement is free from the“curse”of material loss that is inherent to conventional negative index composites.

关键词： photonics,biaxial materials negative index of refraction nonlinear optics

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Experimental observation of coupled valley and spin Hall effect in p-doped WSe2 devices

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InfoMat 2020年第5期2卷 968-974页

作者： Terry Y.T.Hung Avinash Rustagi Shengjiao Zhang Pramey Upadhyaya Zhihong Chen school of electrical and computer engineering Purdue UniversityWest LafayetteIndiana birck nanotechnology center Purdue UniversityWest LafayetteIndiana

It is generally accepted that perpendicular magnetic anisotropy(PMA)magnets are preferred over in-plane magnetic anisotropy(IMA)magnets in data storage applications owing to their large thermal stability even at ultra-scaled dimensions.To efficiently and deterministically switch a PMA,out-of-plan spin current is required.However,conventional giant spin Hall effect(GSHE)materials only produce spin currents with in-plane polarization.Our work,on the other hand,demonstrated for the first time that out-of-plane spin currents can indeed be generated by applying electric filed to monolayer WSe2 at room temperature and the spin information was detected by a graphene channel.Supported by theoretical calculations,we found that the interfacial polarization between graphene and WSe2 to be^38%assuming the ferromagnetic detector's polarization efficiency to be^4%.Moreover,the spin polarization is determined by the polarity of the applied electric field.

关键词： Coupled valley and spin Hall effect Perpendicular magnetic anisotropy WSe2

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