检索结果-南通市图书馆

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

引用

Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou Ru Ye Liyan Zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun community health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Influence of comorbidity on outcomes of older patients with acute pancreatitis based on a national administrative database

引用

Hepatobiliary & Pancreatic Diseases International 2015年第4期14卷 422-428页

作者： Atsuhiko Murata Makoto Ohtani Keiji Muramatsu Shinya Matsuda Department of Preventive Medicine and community health School of Medicine University of Occupational and Environmental Health

Little information is available on the influ- ence of comorbidities on outcomes of older patients with acute pancreatitis. This study aimed to investigate the influence of co- morbidities on outcomes of older patients with acute pancreati- tis using data from a national Iapanese administrative database. METHODS： A total of 14 322 older patients （〉70 years） with acute pancreatitis were referred to 1090 hospitals between 2010 and 2012 in Japan. We collected patients＇ data from the administrative database to compare the in-hospital mortal- ity and length of stay of older patients with acute pancreatitis. The patients were categorized into four groups according to comorbidity level using the Charlson Comorbidity Index （CCI）： none （CCI score=0; n=6890）; mild （1; n=3874）; moder- ate （2; n=2192） and severe （〉3; n=1366）. RESULTS： Multiple logistic and linear regression analyses revealed that severe comorbidity was significantly associated with higher in-hospital mortality and longer length of stay [odds ratio （OR）=2.26; 95% confidence interval （CI）： 1.75-2.92, P〈0.001 and coefficient 4.37 days; 95% CI： 2.89-5.85, P〈0.001, respectively]. In addition, cardiovascular and renal diseases were the most significant comorbidities affecting outcomes of the older patients. ORs of cardiovascular and renal diseases for mortality were 1.44 （95% CI： 1.13-1.85, P=0.003） and 2.69 （95% CI： 1.88-3.85, P〈0.001）, respectively, and coefficients forlength of stay were 3.01 days （95% CI： 1.34-4.67, P〈0.001） and 3.72 days （95% CI： 1.01-6.42, P=0.007）, respectively. CONCLUSION： This study demonstrated that comorbidities significantly influenced outcomes of older patients with acute pancreatitis and cardiovascular and renal comorbidities were significant factors affecting outcomes.

关键词： acute pancreatitis comorbidity length of stay databases

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Molecular Structure Tailoring of Organic Spacers for High‑Performance Ruddlesden–Popper Perovskite Solar Cells

引用

Nano-Micro Letters 2025年第2期17卷 314-357页

作者： Pengyun Liu Xuejin Li Tonghui Cai Wei Xing Naitao Yang Hamidreza Arandiyan Zongping Shao Shaobin Wang Shaomin Liu school of Materials Science and Engineering State Key Laboratory of Heavy Oil ProcessingChina University of Petroleum(East China)Qingdao 266580People’s Republic of China school of Chemistry and Chemical Engineering Shandong University of TechnologyZibo 255049People’s Republic of China Centre for Applied Materials and Industrial Chemistry(CAMIC) School of ScienceRMIT UniversityMelbourneVic 3000Australia WA school of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6102Australia school of Chemical Engineering The University of AdelaideAdelaideSA 5005Australia school of Engineering Great Bay UniversityDongguan 523000People’s Republic of China

Layer-structured Ruddlesden–Popper(RP)perovskites(RPPs)with decent stability have captured the imagination of the photovoltaic research community and bring hope for boosting the development of perovskite solar cell(PSC)***,two-dimensional(2D)or quasi-2D RP PSCs are encountered with some challenges of the large exciton binding energy,blocked charge transport and poor film quality,which restrict their photovoltaic ***,these issues can be readily resolved by rationally designing spacer cations of *** review mainly focuses on how to design the molecular structures of organic spacers and aims to endow RPPs with outstanding photovoltaic *** firstly elucidated the important roles of organic spacers in impacting crystallization kinetics,charge transporting ability and stability of *** we brought three aspects to attention for designing organic ***,we presented the specific molecular structure design strategies for organic spacers of RPPs aiming to improve photovoltaic performance of RP *** proposed strategies in this review will provide new avenues to develop novel organic spacers for RPPs and advance the development of RPP photovoltaic technology for future applications.

关键词： Ruddlesden-Popper perovskites Low-dimensional perovskite solar cells Organic spacers Molecular structure Design strategies

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Accumulation of Visceral Fat and Preventive Measures among the Elderly

引用

Cardiovascular Innovations and Applications 2020年第2期4卷 279-285页

作者： Israel Oluwasegun Ayenigbara school health and community health Unit Department of Health EducationUniversity of IbadanIbadanNigeria

Visceral fat is a specifi c fat that is produced in the body,transformed into cholesterol,and circulated in the blood to other parts of the *** circulated cholesterol usually in the form of low-density lipoproteins forms plaque on the walls of the arteries,thereby constricting and blocking them and preventing the free fl ow of nutrients to various vital organs in the *** fat is deleterious to the health of elderly people because it is mostly found in the region of the abdomen that houses vital organs such as the pancreas,liver,and digestive tract,and it further affects the normal functioning of hormones in the ***,15 million people die of a noncommunicable disease(NCD)annually between the age of 30 years and the age of 69 years,and there is an increase in NCD morbidity among people older than 70 *** visceral fat in elderly people could have deleterious health consequences,as it is a predisposing factor for many other NCDs and chronic health *** lifestyle,unhealthy eating,stress,and inactivity are the major causes of excessive visceral ***,measures to prevent the accumulation of visceral fat are straightforward,and impressive results are achieved with regular physical exercise,healthy diet choices,and proper stress management.

关键词： visceral fat prevention healthy diet exercise stress management

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Correlates of first dose of measles vaccination delivery and uptake in Indonesia

引用

Asian Pacific Journal of Tropical Medicine 2011年第2期4卷 140-145页

作者： Renae Fernandez Anu Rammohan Niyi Awofeso school of Population health University of Western AustraliaAustralia school of Business Discipline of EconomicsUniversity of Western AustraliaAustralia school of Public health and community Medicine University of New South WalesAustralia

Objective:To determine health systems-related,familial,and cultural factors which influence the delivery and uptake of measles vaccination in ***:Logistic regression analysis of data collected during the 2007 Indonesian Demographic and health Survey was undertaken by the authors to investigate these *** 2007 Indonesian Demographic and health Survey dataset is a nationally representative,randomly sampled survey containing 15 065 children aged between 9 and 59 ***:72.8%of children had received the measles *** coverage was similar for males and females;however,coverage was higher amongst urban children,80.1%,compared to 68.5%in rural *** key findings of the regression analysis were congruent with the results of previous research targeting vaccination *** controlling for all other factors,maternal age,maternal education,wealth, the use of a skilled birth attendant,and postnatal check-ups were positively and significantly (Phealth education and health systems improvements are also required.

关键词： Measles Indonesia Vaccination Rural-urban differences Maternal education

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medical Consultations Option and Influencing Factors for SARS-CoV-2 Infected Individuals-Beijing Municipality,China,December 2022

引用

China CDC weekly 2023年第26期5卷 572-578,I0003-I0005页

作者： Mingyue Li Jue Liu Ming Du Chen Wang Yafang Huang Wentao Li Tong Xiang Jingwei Zhao Xiaoli Zhu Xinying Dong Hao Wu Shugang Li school of General Practice and Continuing Education Capital Medical UniversityBeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Beijing community health Service Association BeijingChina school of Public health Capital Medical UniversityBeijingChina

Summary What is already known about this topic?In December 2022,China revised its epidemic prevention and control strategy,leading to an increase in coronavirus disease 2019(COVID-19)cases and a peak in medical *** departments implemented relevant policies to coordinate and allocate medical resources throughout ***,there is a scarcity of research on the status of medical consultations and the factors influencing them.

关键词： Influencing China. prevention

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Editorial commentary on special issue of COVID-19 pandemic

引用

The Journal of Biomedical Research 2020年第6期34卷 395-396页

作者： Wei Yang school of community health Sciences University of NevadaRenoNV 89557USA.

This special issue of The Journal of Biomedical Research presents rigorous empirical analysis related to COVID-19 research in responding to the current global COVID-19 *** articles from different disciplines not only offer broader perspectives on combating the outbreaks,but also disseminate the most updated findings on this new challenge for human being to the field.

关键词： COVID-19 SARS-CoV-2 coronavirus pandemic outbreak

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Biofilm three-dimensional architecture influences in situ pH distribution pattern on the human enamel surface

引用

International Journal of Oral Science 2017年第2期9卷 74-79页

作者： Jin Xiao Anderson T Hara Dongyeop Kim Domenick T Zero Hyun Koo Geelsu Hwang Eastman Institute for Oral health University of Rochester Medical Center Department of Cariology Operative Dentistry and Dental Public HealthOral Health Research InstituteIndiana University School of Dentistry Biofilm Research Laboratories Levy Center for Oral HealthDepartment of Orthodontics and Divisions of Pediatric Dentistry & Community Oral HealthSchool of Dental MedicineUniversity of Pennsylvania

To investigate how the biofilm three-dimensional(3D) architecture influences in situ pH distribution patterns on the enamel surface. Biofilms were formed on human tooth enamel in the presence of 1% sucrose or 0.5% glucose plus 0.5% fructose. At specific time points, biofilms were exposed to a neutral pH buffer to mimic the buffering of saliva and subsequently pulsed with 1% glucose to induce re-acidification. Simultaneous 3D pH mapping and architecture of intact biofilms was performed using two-photon confocal microscopy. The enamel surface and mineral content characteristics were examined successively via optical profilometry and microradiography analyses. Sucrose-mediated biofilm formation created spatial heterogeneities manifested by complex networks of bacterial clusters(microcolonies). Acidic regions(pH<5.5) were found only in the interior of microcolonies,which impedes rapid neutralization(taking more than 120 min for neutralization). Glucose exposure rapidly re-created the acidic niches, indicating formation of diffusion barriers associated with microcolonies structure. Enamel demineralization(white spots),rougher surface, deeper lesion and more mineral loss appeared to be associated with the localization of these bacterial clusters at the biofilm-enamel interface. Similar 3D architecture was observed in plaque-biofilms formed in vivo in the presence of sucrose. The formation of complex 3D architectures creates spatially heterogeneous acidic microenvironments in close proximity of enamel surface, which might correlate with the localized pattern of the onset of carious lesions(white spot like) on teeth.

关键词： biofilms demineralization dental caries exopolysaccharides microcolonies pH microenvironments plaque Streptococcus mutans

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Spatial distribution and habitat characterization of mosquito species during the dry season along the Mara River and its tributaries,in Kenya and Tanzania

引用

Infectious Diseases of Poverty 2018年第1期7卷 14-29页

作者： Gabriel O.Dida Douglas N.Anyona Paul O.Abuom Daniel Akoko Samson O.Adoka Ally-Said Matano Philip O.Owuor Collins Ouma school of Public health and community Development Maseno UniversityMasenoKenya school of Environment and Earth Sciences Maseno UniversityMasenoKenya Impact Research and Development Organization KisumuKenya school of health Sciences Jaramogi Oginga Odinga University of Science and TechnologyBondoKenya East African community/Lake Victoria Basin Commission KisumuKenya Department of Chemistry Maseno UniversityMasenoKenya Department of community and Public health Technical University of KenyaNairobiKenya

Background:Vector-borne diseases are increasingly becoming a major health problem among communities living along the major rivers of *** larger water bodies such as lakes and dams have been extensively researched,rivers and their tributaries have largely been *** study sought to establish the spatial distribution of mosquito species during the dry season and further characterize their habitats along the Mara River and its ***:In this cross-sectional survey,mosquito larvae were sampled along the Mara River,its two perennial tributaries(Amala and Nyangores),drying streams,and adjacent aquatic habitats(***,puddles that receive direct sunlight[open sunlit puddles],rock pools,hippo and livestock hoof prints,and vegetated pools).Each habitat was dipped 20 times using a standard *** between breeding sites and human habitation was determined using global positioning system *** collected mosquito larvae were identified using standard taxonomic *** physico-chemical parameters were measured in situ using a multiparameter *** mosquito larvae per habitat type were compared using analysis of variance and chi-square tests,while the relationship between mosquito larvae and physicochemical parameters was evaluated using a generalized linear mixed *** Cox-Stuart test was used to detect trends of mosquito larvae *** test allowed for verification of monotonic tendency(rejection of null hypothesis of trend absence)and its ***:A total of 4001 mosquito larvae were collected,of which 2712(67.8%)were collected from river/stream edge habitats and 1289(32.2%)were sampled from aquatic habitats located in the terrestrial ecosystem about 50 m away from the main river/*** gambiae s.s,***,and *** group,the three most potent vectors of malaria in Sub-Saharan Africa,together with other anopheline mosquitoes,were the most dominant mosquito species(70.3%)

关键词： Anopheles gambiae Anopheles funestus Culex Mosquito Larval habitat Mara River Kenya Tanzania

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Present status of endoscopic mastectomy for breast cancer

引用

World Journal of Clinical Oncology 2015年第3期6卷 25-29页

作者： Tetsuhiro Owaki Yuko Kijima Heiji Yoshinaka Munetsugu Hirata Hiroshi Okumura Simiya Ishigami Yasuhito Nerome Toshiro Takezaki Shoji Natsugoe community-based Medicine Graduate School of Medical and Dental HealthKagoshima University

Endoscopy is now being used for breast cancer surgery. Though it is used for mastectomy, lymph node dissection, and breast reconstruction, its prime use is for mastectomy. Because an incision can be placed inconspicuously in the axillary site, a relatively largeincision can be created. A retractor with an endoscope, CO2, and an abrasion device with the endoscope are used for operation space security. It is extremely rare that an endoscope is used for lymph node dissection. For breast reconstruction, it may be used for latissimus muscle flap making, but an endoscope is rarely used for other reconstructions. Endoscopic mastectomy is limited to certain institutions and practiced hands, and it has not been significantly developed in breast cancer surgery. On the other hand, endoscopic surgery may be used widely in breast reconstruction. With respect to the spread of robotic surgery, many factors remain uncertain.

关键词： Endoscopy Video-assisted Breast cancer Surgery Mastectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：