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Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei Tang Jinyu Zeng Yige Song Chao Xu Kai Zhao Guoqiang Liu Youming Lu Xinyan Li Kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

An Active-Set Projected Trust Region Algorithm for Box Constrained Optimization Problems

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Journal of Systems science & Complexity 2015年第5期28卷 1128-1147页

作者： YUAN Gonglin WEI Zengxin ZHANG Maojun College of mathematics and Information science Guangxi University school of Mathematic and computing science Guilin University of Electronic Technology

An active-set projected trust region algorithm is proposed for box constrained optimization problems, where the given algorithm is designed by three steps. First, the projected gradient direction which normally has better numerical performance is introduced. Second, the projected trust region direction that often possesses good convergence is defined, where the matrix of trust region subproblem is updated by limited memory strategy. Third, in order to get both good numerical performance and convergence, the authors define the final search which is the convex combination of the projected gradient direction and the projected trust region direction. Under suitable conditions, the global convergence of the given algorithm is established. Numerical results show that the presented method is competitive to other similar methods.

关键词： Active-set strategy convergence trust region

Lipschitz continuity of the optimal value function and KKT solution set in indefinite quadratic programs

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Applied mathematics(A Journal of Chinese Universities) 2015年第1期30卷 102-110页

作者： HAN You-pan CHEN Zhi-ping ZHANG Feng school of science Xi’an Polytechnic University Department of computing science School of Mathematics and Statistics Xi’an Jiaotong University

When all the involved data in indefinite quadratic programs change simultaneously, we show the locally Lipschtiz continuity of the KKT set of the quadratic programming problem firstly, then we establish the locally Lipschtiz continuity of the KKT solution set. Finally, the similar conclusion for the corresponding optimal value function is obtained.

关键词： quadratic program Lipschitz continuity value function feasible solution KKT solution set.

Bifurcation of travelling wave solutions for (2+1)-dimension nonlinear dispersive long wave equation

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Applied mathematics(A Journal of Chinese Universities) 2009年第3期24卷 291-297页

作者： RONG Ji-hong TANG Sheng-qiang school of mathematics and computing science,Guilin University of Electronic Technology,Guilin541004,China school of mathematics and computing science Guilin University of Electronic Technology Guilin China

In this paper,the bifurcation of solitary,kink,anti-kink,and periodic waves for （2＋1）-dimension nonlinear dispersive long wave equation is studied by using the bifurcation theory of planar dynamical *** parameter sets are shown,and under various parameter conditions,all exact explicit formulas of solitary travelling wave solutions and kink travelling wave solutions and periodic travelling wave solutions are listed.

关键词： solitary wave kink and anti-kink wave periodic wave (2+1)-Dimension nonlinear dispersive long wave equation

Miyaoka-type inequalities for terminal threefolds with nef anti-canonical divisors

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science China mathematics 2025年第1期 1-18页

作者： Masataka Iwai Chen Jiang Haidong Liu Department of mathematics Graduate School of ScienceOsaka University Shanghai Center for Mathematical sciences & school of Mathematical sciences Fudan University Department of mathematics Sun Yat-sen University

In this paper,we study Miyaoka-type inequalities on Chern classes of terminal projective 3-folds with nef anti-canonical *** X be a terminal projective 3-fold such that-KXis *** show that if c1（X） · c2（X）≠0,then c1（X） · c2（X） ≥ 1/252;if further X is not rationally connected,then c1（X） · c2（X） ≥ 4/5 and this inequality is *** order to prove this,we give a partial classification of such varieties along with many *** also study the nonvanishing of c1（X）dim X-2· c2（X） for terminal weak Fano varieties and prove a Miyaoka-Kawamata-type inequality.

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Influence of introducing Zr,Ti,Nb and Ce elements on externally solidified crystals and mechanical properties of high-pressure die-casting Al–Si alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 147-153页

作者： Junjie Li Wenbo Yu Zhenyu Sun Weichen Zheng Liangwei Zhang Yanling Xue Wenning Liu Shoumei Xiong Center of Materials science and Engineering School of Mechanical and Electronic Control EngineeringBeijing Jiaotong UniversityBeijing 100044China Traffic&Transportation Engineering Central South UniversityChangsha 410075China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China school of Materials science and Engineering Tsinghua UniversityBeijing 100084China

High pressure die casting(HPDC)AlSi10Mn Mg alloy castings are widely used in the automobile *** can optimize the mechanical properties of castings through heat treatment,while the release of thermal stress arouses the deformation of large integrated ***,the development of non-heat treatment Al alloys is becoming the hot *** addition,HPDC contains externally solidified crystals(ESCs),which are detrimental to the mechanical properties of *** achieve high strength and toughness of non-heat treatment die-casting Al-Si alloy,we used AlSi9Mn alloy as matrix with the introduction of Zr,Ti,Nb,and *** influences on ESCs and mechanical properties were systematically investigated through three-dimensional reconstruction and thermodynamic *** results reveal that the addition of Ti increased ESCs'size and porosity,while the introduction of Nb refined ESCs and decreased ***,large-sized Al_3(Zr,Ti)phases formed and degraded the mechanical *** introduction of Ce resulted in the poisoning effect and reduced mechanical properties.

关键词： aluminium alloy high-pressure die-casting externally solidified crystals non-heat treatment

Existence and Nonexistence of Global Positive Solutions for a Weakly Coupled P-Laplacian System

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Acta Mathematicae Applicatae Sinica 2013年第3期29卷 541-554页

作者： Xian-zhong ZENG Zhen-hai LI Yong-geng GU school of mathematics and computing science Hunan University of Science and Technology College of science Guangxi University for Nationalities Department of mathematics Hunan Normal University

In this paper, we deal with a weakly coupled evolution P-Laplacian system with inhomogeneous terms. We obtain a critical criterion concerning existence and nonexistence of its global positive solutions. Such a criterion is different from that of the weakly coupled evolution P-Laplacian system with homogeneous terms. Further, we demonstrate existence and nonexistence of its global positive solutions.

关键词： the evolution P-Laplacian system inhomogeneous terms blow-up global existence

Periodic solutions and flip bifurcation in a linear impulsive system

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Chinese Physics B 2008年第11期17卷 4114-4122页

作者：蒋贵荣杨启贵 school of Mathematical sciences South China University of Technology school of mathematics and computing science Guilin University of Electronic Technology

In this paper, the dynamical behaviour of a linear impulsive system is discussed both theoretically and numerically. The existence and the stability of period-one solution are discussed by using a discrete map. The conditions of existence for flip bifurcation are derived by using the centre manifold theorem and bifurcation theorem. The bifurcation analysis shows that chaotic solutions appear via a cascade of period-doubling in some interval of parameters. Moreover, the periodic solutions, the bifurcation diagram, and the chaotic attractor, which show their consistence with the theoretical analyses, are given in an example.

关键词： linear impulsive equation periodic solution flip bifurcation

From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu Jun Shen Xin Zhang Lingcong Chao Liang Chen Ding Zhang Tao Wei Shoudong Xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China school of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China school of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added