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Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou Ru Ye Liyan Zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang district HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

Optimization of Convolutional Neural Network Based on Improved Sparrow Algorithm for Flywheel Energy Storage System Loss in Small Sample

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Dianwang Jishu/Power System Technology 2025年第1期49卷 366-372页

作者： Wei, Le Li, Chenglin Fang, Fang Liu, Yubin school of Control and Computer Engineering North China Electric Power University Changping District Beijing 102206 China

Flywheel energy storage systems have standby losses and are unsuitable for long-term energy storage. Aiming at the economic index of flywheel loss, based on the small sample data of the operation of the flywheel energy storage system, a flywheel loss calculation model combining a Logistic chaotic sparrow optimization algorithm and a convolutional neural network was proposed. Firstly, the causes of flywheel loss were analyzed. Next, the flywheel operation data of Ningxia Lingwu Power Plant was preprocessed, and the adversarial generation network was used for small-sample enrichment. Then, the loss model is established based on the convolutional neural network, the improved sparrow algorithm is used to optimize the hyperparameters of the model, and the superiority of the model is verified by comparison. Finally, simulation experiments show that the model can optimize the output of the flywheel energy storage system and reduce the flywheel loss. © 2025 Power System Technology Press. All rights reserved.

关键词： Flywheels

Daily Intra Day Collaborative Rolling Optimization Strategy for Solar Energy Storage Power Stations Participating in Multiple Application Scenarios

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Dianwang Jishu/Power System Technology 2025年第1期49卷 198-208页

作者： Liu, Zifa Li, Kunyang Zheng, Siqi school of Electrical and Electronic Engineering North China Electric Power University Changping District Beijing 102206 China

The joint operation of photovoltaic power stations and energy storage systems can reduce the uncertainty of power output from the power supply side and improve the stability of the power grid. The current application scenarios for solar energy storage power stations are relatively single, making it difficult to simultaneously consider primary and secondary frequency regulation and joint electricity sales. In response to this issue, this paper proposes a multi-scenario compatible day-ahead rolling optimization operation strategy that considers the electricity market and primary and secondary frequency regulation services. Firstly, the characteristics of primary and secondary frequency modulation signals will be analyzed, and a collaborative optimization strategy framework for hybrid energy storage in photovoltaic power plants will be proposed under multi-application scenario scheduling resolution. Then, to maximize the joint revenue of the station, a daily optimization model is established that considers the secondary frequency regulation capacity of energy storage. In the intraday stage, the actual output priority of each scenario is considered, and a rolling optimization solution is obtained to obtain the operation plan of the energy storage system. Using actual data from a photovoltaic power station in Daqing, Heilongjiang Province, simulation verification was conducted, and sensitivity analysis was conducted on the model. The example shows that the optimization strategy proposed in this paper can unleash the scheduling potential of different energy storage resources, effectively improve the accuracy of power station reporting and frequency regulation ability. © 2025 Power System Technology Press. All rights reserved.

关键词： Sensitivity analysis

Subretinal fibrosis secondary to neovascular age-related macular degeneration:mechanisms and potential therapeutic targets

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Neural Regeneration Research 2025年第2期20卷 378-393页

作者： Jingxiang Zhang Xia Sheng Quanju Ding Yujun Wang Jiwei Zhao Jingfa Zhang Department of Ophthalmology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Urology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Ophthalmology Shanghai General Hospital(Shanghai First People’s Hospital)Shanghai Jiao Tong University School of MedicineShanghaiChina National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghaiChina

Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular *** causes local damage to photoreceptors,retinal pigment epithelium,and choroidal vessels,which leads to permanent central vision loss of patients with neovascular age-related macular *** pathogenesis of subretinal fibrosis is complex,and the underlying mechanisms are largely ***,there are no effective treatment options.A thorough understanding of the pathogenesis of subretinal fibrosis and its related mechanisms is important to elucidate its complications and explore potential *** current article reviews several aspects of subretinal fibrosis,including the current understanding on the relationship between neovascular age-related macular degeneration and subretinal fibrosis;multimodal imaging techniques for subretinal fibrosis;animal models for studying subretinal fibrosis;cellular and non-cellular constituents of subretinal fibrosis;pathophysiological mechanisms involved in subretinal fibrosis,such as aging,infiltration of macrophages,different sources of mesenchymal transition to myofibroblast,and activation of complement system and immune cells;and several key molecules and signaling pathways participating in the pathogenesis of subretinal fibrosis,such as vascular endothelial growth factor,connective tissue growth factor,fibroblast growth factor 2,platelet-derived growth factor and platelet-derived growth factor receptor-β,transforming growth factor-βsignaling pathway,Wnt signaling pathway,and the axis of heat shock protein 70-Toll-like receptors 2/*** review will improve the understanding of the pathogenesis of subretinal fibrosis,allow the discovery of molecular targets,and explore potential treatments for the management of subretinal fibrosis.

关键词： choroidal neovascularization epithelial-mesenchymal transition mesenchymal transition myofibroblast neovascular age-related macular degeneration submacular fibrosis subretinal fibrosis therapeutic targets transforming growth factor-β vascular endothelial growth factor

Advancements and Challenges in Organic–Inorganic Composite Solid Electrolytes for All‑Solid‑State Lithium Batteries

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Nano-Micro Letters 2025年第1期17卷 46-97页

作者： Xueyan Zhang Shichao Cheng Chuankai Fu Geping Yin Liguang Wang Yongmin Wu Hua Huo State Key Laboratory of Space Power‑Sources School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310058People’s Republic of China State Key Laboratory of Space Power-Sources 2965 Dongchuan RoadMinhang DistrictShanghai 200240People’s Republic of China

To address the limitations of contemporary lithium-ion batteries,particularly their low energy density and safety concerns,all-solid-state lithium batteries equipped with solid-state electrolytes have been identified as an up-and-coming *** the various SEs,organic–inorganic composite solid electrolytes(OICSEs)that combine the advantages of both polymer and inorganic materials demonstrate promising potential for large-scale ***,OICSEs still face many challenges in practical applications,such as low ionic conductivity and poor interfacial stability,which severely limit their *** review provides a comprehensive overview of recent research advancements in ***,the influence of inorganic fillers on the main functional parameters of OICSEs,including ionic conductivity,Li+transfer number,mechanical strength,electrochemical stability,electronic conductivity,and thermal stability are systematically *** lithium-ion conduction mechanism of OICSE is thoroughly analyzed and concluded from the microscopic ***,the classic inorganic filler types,including both inert and active fillers,are categorized with special emphasis on the relationship between inorganic filler structure design and the electrochemical performance of ***,the advanced characterization techniques relevant to OICSEs are summarized,and the challenges and perspectives on the future development of OICSEs are also highlighted for constructing superior ASSLBs.

关键词： Composite solid electrolytes Inorganic filler Interfacial stability Li-ion conduction mechanism Characterization techniques

Research on Two-stage Voltage and Reactive Power Optimization Coordinated Control Method Considering Flexible On-load Tap Changer

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Dianwang Jishu/Power System Technology 2025年第1期49卷 272-283页

作者： Li, Jiaming Huo, Qunhai Yin, Jingyuan Lu, Hao Zhou, Jing Zhu, Meisheng He, Wei Dong, Hongwei Institute of Electrical Engineering Chinese Academy of Sciences Haidian District Beijing 100192 China school of Electronic Electrical and Communication Engineering University of Chinese Academy of Sciences Shijingshan District Beijing 100049 China Shanghai Jiguang Polytechnic College Baoshan District Shanghai 201901 China Three Gorges Electric Power Co. Ltd. Hubei Province Wuhan 430000 China

With the large-scale integration of distributed photovoltaic (DPV) in the distribution network, voltage exceeding limits and fluctuations are becoming increasingly severe. The voltage and reactive power optimization and coordination control method considering new power quality management devices needs to be further improved to adapt to the new changes in the power grid. This article considers the power quality regulation effect of the new flexible on-load tap changer (OLTC) and proposes a two-stage voltage and reactive power optimization coordinated control method. The first stage is the day before hour level scheduling stage. Based on distributed photovoltaic and load prediction data, the active output results of DPV and the switching results of flexible OLTC taps and capacitor banks are obtained through power flow calculation and iterative optimization. The second stage is the minute-level reactive power optimization stage. Based on the first stage, considering the reactive power output characteristics of flexible OLTC and DPV, adjusting the reactive power output of the equipment while correcting the capacitor bank switching combination in the first stage, further reducing the maximum voltage deviation of each node and making the distribution network voltage distribution more reasonable. An IEEE33 node distribution system simulation model is built in the paper. The proposed two-stage voltage and reactive power optimization coordination control method considering flexible OLTC can improve the DPV absorption level by 9.29% based on the conventional economic optimal goal of 88.07%, while meeting the requirement that the voltage deviation of the entire node is less than 0.1pu During the entire period, the overall economic efficiency improved by 7.8%. The results demonstrate the rationality and effectiveness of the proposed method. © 2025 Power System Technology Press. All rights reserved.

关键词： Quality management

Inter‑Skeleton Conductive Routes Tuning Multifunctional Conductive Foam for Electromagnetic Interference Shielding,Sensing and Thermal Management

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Nano-Micro Letters 2025年第3期17卷 19-36页

作者： Xufeng Li Chunyan Chen Zhenyang Li Peng Yi Haihan Zou Gao Deng Ming Fang Junzhe He Xin Sun Ronghai Yu Jianglan Shui Caofeng Pan Xiaofang Liu school of Materials Science and Engineering Beihang UniversityBeijing 100191People’s Republic of China Institute of Atomic Manufacturing Beihang UniversityBeijing 100191People’s Republic of China Tianmushan Laboratory Xixi Octagon CityYuhang DistrictHangzhou 310023People’s Republic of China Science and Technology On Electromagnetic Scattering Laboratory Beijing Institute of Environmental FeaturesBeijing 100854People’s Republic of China

Conductive polymer foam(CPF)with excellent compressibility and variable resistance has promising applications in electromagnetic interference(EMI)shielding and other integrated functions for wearable ***,its insufficient change amplitude of resistance with compressive strain generally leads to a degradation of shielding performance during ***,an innovative loading strategy of conductive materials on polymer foam is proposed to significantly increase the contact probability and contact area of conductive components under *** inter-skeleton conductive films are constructed by loading alginate-decorated magnetic liquid metal on the polymethacrylate films hanged between the foam skeleton(denoted as AMLM-PM foam).Traditional point contact between conductive skeletons under compression is upgraded to planar contact between conductive ***,the resistance change of AMLM-PM reaches four orders of magnitude under ***,the inter-skeleton conductive films can improve the mechanical strength of foam,prevent the leakage of liquid metal and increase the scattering area of EM ***-PM foam has strain-adaptive EMI shielding performance and shows compression-enhanced shielding effectiveness,solving the problem of traditional CPFs upon *** upgrade of resistance response also enables foam to achieve sensitive pressure sensing over a wide pressure range and compression-regulated Joule heating function.

关键词： Inter-skeleton conductive films Conductive polymer foam Liquid metal Electromagnetic interference shielding

Properties of ground state and anomalous quantum fluctuations in one-dimensional polaron-soliton systems-the effects of electron-two-phonon interaction and non-adiabatic quantum correlations

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Chinese Physics B 2011年第6期20卷 372-383页

作者：罗质华曹锡金余超凡 Department of Physics Guangdong University of Education Pinggang Middle school Longgang District

Based on the Holstein model Hamiltonian of one-dimensional molecular crystals, by making use of the expansion approach of the correlated squeezed-coherent states of phonon instead of the two-phonon coherent state expansion scheme, the properties of the ground state and the anomalous quantum fluctuations are investigated in a strongly coupled electron-phonon system with special consideration of the electron-two-phonon interaction. The effective renormalization （ai） of the displacement of the squeezed phonons with the effect of the squeezed-coherent states of phonon and both the electron-displaced pbonon and the polaron-squeezed phonon correlations have been combined to obtain the anomalous quantum fluctuations for the corrections of the coherent state. Due to these non-adiabatic correlations, the effective displacement parameter ai is larger than the ordinary parameter ai （0） In comparison with the electron-one-phonon interaction （g） corrected as oig, we have found the electron-two-phonon interaction （gl） corrected as ai2gi is enhanced significantly. For this reason, the ground state energy （E（2）） contributed by the electron-two-phonon interaction is more negative than the single-phonon case （E01）） and the soliton solution is more stable. At the same time, the effects of the electron-two-phonon interaction greatly increase the polaron energy and the quantum fluctuations. Furthermore, in a deeper level, we have considered the effect of the polaron-squeezed phonon correlation （f-correlation）. Since this correlation parameter f 〉 1, this effect will strengthen the electron-one and two-phonon interactions by fai9 and f2ai2g1, respectively. The final results show that the ground state energy and the polaron energy will appear more negative further and the quantum fluctuations will gain further improvement.

Hydraulic characteristics of an anaerobic baffled reactor as onsite wastewater treatment system

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Journal of Environmental Sciences 2010年第9期22卷 1319-1326页

作者： Yuttachai Sarathai Thammarat Koottatep Antoine Morel school of Environment Resources and Development Asian Institute of Technology Eawag:Swiss Federal Institute for Aquatic Science & Technology Department for Water and Sanitation in Developing Countries(Sandec)

The feasibility of using anaerobic baffled reactor （ABR） as onsite wastewater treatment system was discussed. The ABR consisted of one sedimentation chamber and three up-flow chambers in series was experimented under different peak flow factors （PFF of 1 to 6）, superficial gas velocities （between 0.6 and 3.1 cm/hr） and hydraulic retention times （HRT）（24, 36 and 48 hr）. Residence time distribution （RTD） analyses were carded out to investigate the hydraulic characteristics of the ABR. It was found that the PFF resulted in hydraulic dead space. The dead space did not exceed 13% at PFF of 1, 2 and 4 while there was 2-fold increase （26%） at PFF of 6. Superficial gas velocities did not result in more （biological） dead space. The mixing pattern of ABR tended to be a completely- mixed reactor when PFF increased. Superficial gas velocities did not affect mixing pattern. The effects of PFF on mixing pattern could be minimized by higher HRT （48 hr）. The tank-in-series （TIS） model （N = 4） was suitable to describe the hydraulic behaviour of the studied system. The HRT of 48 hr was able to maintain the mixing pattern under different flow patterns, introducing satisfactory hydraulic efficiency. Chemical oxygen demand （COD） and total suspended solids （TSS） removals under all flow patterns were achieved more than 85% and 90%, respectively. The standard deviation of effluent COD and TSS concentration did not exceed 15 mg/L.

关键词： anaerobic baffled reactor dead space hydraulic characteristics onsite system peak flow factor