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Prostaglandin E1 administration post liver transplantation and renal outcomes:A retrospective single center experience

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World Journal of Transplantation 2024年第4期14卷 101-109页

作者： Vinay Jahagirdar Mohamed Ahmed Ifrah Fatima Hassam Ali Laura Alba John H Helzberg Lee s Cummings Matthew Wilkinson Jameson Forster Alisa Likhitsup Department of Internal Medicine Saint Luke’s Health System of Kansas City and the University of Missouri-Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Internal Medicine Department of Gastroenterology and HepatologySaint Luke’s Health System of Kansas City and University of Missouri-Kansas CityKansas CityMO 64111United States Department of surgery University of Missouri-Kansas City and Transplant SurgerySaint Luke’s Hospital of Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Prostaglandin E1(PGE1),or alprostadil,is a potent vasodilator that improves hepatic blood flow and reduces ischemia-reperfusion injury post-liver transplantation(LT).However,the benefits of PGE1 on renal function after LT have not yet been well *** To assess the impact of PGE1 administration on renal function in patients who underwent liver or liver-kidney *** This retrospective study included all patients who underwent liver or liverkidney transplant at our institution from January,2011 to December,*** were classified based on whether they received ***1 was administered post-LT to those with transaminases>1000 U/L in the immediate postoperative ***,post-LT treatments and/or complications,renal function,and survival were *** logistic regression analysis was performed,and a two-tailed P values considered statistically *** A total of 145 patients underwent LT,with 44(30%)receiving *** patient characteristics were comparable,except the PGE1 group had significantly higher aspartate aminotransferase(AsT)(1961.9 U/L±1862.3 U/L vs 878 U/L±741.4 U/L,P=0.000),alanine aminotransferase(1070.6 U/L±895 U/L vs 547.7 U/L±410 U/L,P=0.000),international normalized ratio on post-LT day 1(2±0.74 vs 1.8±0.4,P=0.03),a longer intensive care unit stay(8.1 days±11.8 days vs 3.8 days±4.6 days,P=0.003),more vasopressor use(55.53 hours±111 hours vs 16.33 hours±26.3 hours,P=0.002),and higher immediate postoperative complications(18.6%vs 4.9%,P=0.04).The PGE1 group also had a significantly higher 90-day readmission rate(29.6%vs 13.1%,P=0.02)and lower 1-year liver graft survival(87.5%vs 98.9%,P=0.005).However,30-day readmission(31.6%vs 27.4%,P=0.64),LT complications(hepatic artery thrombosis,biliary complications,rejection of liver graft,cardiomyopathy),1-year patient survival(96.9%vs 97.8%,P=0.77),overall liver graft survival,and overall patient survival were similar between t

关键词： Liver transplantation Alprostadil Protective agents Transplant Prostaglandin E1

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Isolated Third Nerve Cranial Palsy: Complication of Brain Aneurysm

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surgical science 2024年第4期15卷 225-231页

作者： Diana Magiricu Michelle Garcia-Rybkin Internal Medicine Department Montefiore St. Luke&#8217s Cornwall Hospital Newburgh NY USA Emergency Medicine Department Montefiore St. Luke&#8217s Cornwall Hospital Newburgh NY USA

This case report highlights a critical and emergent condition, isolated third nerve cranial palsy due to a brain aneurysm. It emphasizes the importance of differential diagnosis and attentiveness to the physical exam in an emergency setting. The detailed progression from initial symptoms and misinterpretation to final diagnosis offers valuable insight into the dangers of overlooking critical diagnoses. A bilobed intracranial aneurysm arising from the internal carotid artery (ICA) caused symptoms in this patient that could have been attributed to a less malignant etiology, such as a complex migraine. Overlooking the urgency of the situation and missing the diagnosis could have had a grave and irreversible outcome.

关键词： Migraine Brain Aneurysm

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Changes of growth-climate relationships of smith fir forests along an altitudinal gradient

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Journal of Forestry Research 2024年第5期35卷 37-46页

作者： Jiacheng Zheng Jing Yang Hengfeng Jia Lixin Lyu Jiayang Langzhen Qi-Bin Zhang state Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093People’s Republic of China University of Chinese Academy of sciences Beijing 100049People’s Republic of China Linzhou Bureau of Meteorology LinzhouLhasa 851611TibetPeople’s Republic of China institute of Plateau Ecology Tibet Agricultural and Animal Husbandry UniversityLinzhi 860000TibetPeople’s Republic of China

Temporal changes in the relationship between tree growth and climate have been observed in numerous forests across the *** patterns and the possible regu-lators(e.g.,forest community structure)of such changes are,however,not well understood.A vegetation survey and analyses of growth-climate relationships for Abies georgei ***(smith fir)forests were carried along an altitudi-nal gradient from 3600 to 4200 m on Meili snow Mountain,southeastern Tibetan *** results showed that the associations between growth and temperature have declined since the 1970s over the whole transect,while response to standardized precipitation-evapotranspiration indices(sPEI)strengthened in the mid-and *** between growth and vegetation data showed that tree growth was more sensitive to drought in stands with higher species richness and greater shrub *** stress on growth may be increased by heavy competition from shrub and herb *** results show the non-stationary nature of tree growth-climate associations and the linkage to for-est community *** components should be considered in future modeling and forecasting of forest dynamics in relation to climate changes.

关键词： Climate change Tree rings Altitudinal gradient Community structure Plant diversity

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Optimal interval for delayed retrieval surgery with reciprocating morcellators after enucleation of giant prostatic hyperplasia in holmium laser enucleation of the prostate

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Asian Journal of Urology 2024年第3期11卷 423-428页

作者： Fumiyasu Endo Masaki shimbo Kenji Komatsu Kazuhiro Ohwaki Kazunori Hattori Department of Urology St.Luke’s International Hospital9-1 Akashi-choChuo-kuTokyoJapan Department of Hygiene and Public Health Teikyo University School of Medicine Graduate School of Medicine2-11-1 KagaItabashi-kuTokyoJapan

Objective:The aim of this research was to evaluate the efficiency of reciprocating morcellation for removing giant benign prostatic hyperplasia during holmium laser enucleation of the prostate,investigate whether performing morcellation as a two-stage procedure improves tissue retrieval efficiency,and seek to determine the optimal interval between the two ***:This study included nine cases of holmium laser enucleation of the prostate with an enucleated prostate weight exceeding 200 g,indicative of substantial prostate *** was performed on Day 0(n=4),Day 4(n=1),Day 6(n=1),and Day 7(n=3).The intervals were compared regarding the morcellation efficiency,beach ball presence,and ***:The mean estimated prostate volume was 383(range 330e528)mL;the median enucleation weight was 252(interquartile range[IQR]222,342)g;and the median enucleation time was 83(IQR 62,100)*** mean morcellation efficiency was 1.44(sD 0.55)g/min on Day 0 and 13.69(sD 2.46)g/min on day *** morcellation efficiency was 4.15 g/min and 10.50 g/min on Day 4 and Day 6,respectively,with significantly higher in the two-stage group compared to one-stage group(11.0 g/min vs.1.5 g/min;p=0.014).Efficiency was strongly correlated with intervals(ps of beach balls were 100%(4/4)and 60%(3/5)in the immediate and two-stage surgery groups,***:The efficiency of two-stage morcellation with reciprocating morcellators was highly related to the postoperative interval,with the maximum efficiency reached on Day 7.

关键词： Holmiumlaser enucleationofthe prostate Reciprocating morcellator Giant adenoma Two-stage surgery

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Parameter matching and experiment of the combined cyclone separation and cylinder sieve cleaning system for rape combine harvester

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International Journal of Agricultural and Biological Engineering 2024年第1期17卷 128-136页

作者： Jiacheng Yuan Qingxi Liao Xingyu Wan Jia Yang Caixia shu College of Engineering Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Agricultural Equipment in mid-lower Yangtze River Ministry of Agriculture and Rural AffairsWuhan 430070China

Existing rape combine harvester with a cyclone separation cleaning device has the challenge that the loss rate and the cleaning rate increase and decrease simultaneously.A cleaning process route was proposed,which involves the cyclone separation cleaning device removing light and tiny impurities,and the cylinder sieve device removing coarse and long impurities such as pod shells and short stems.A novel cleaning system combining the cyclone separation cleaning device and cylinder sieve cleaning devices was *** ranges of the structure and operation parameters for each component were analyzed based on kinematics and dynamic analysis.A four-factor five-level quadratic orthogonal test was carried out,in which the loss rate and cleaning rate were taken as the evaluation *** velocity at the suction port,the rotation speed of the cylinder sieve,the screw pitch of the spiral blade and the diameter of the sieve hole were taken as the influencing *** orthogonal test results showed that the cleaning system performed best at a rotation speed of the winnower is 600 r/min,an airflow velocity at the suction port is 18.25 m/s,a rotation speed of the cylinder sieve is 87 r/min,a screw pitch of the spiral blade is 440 mm and a diameter of the sieve hole is 4.48 *** this time,the loss rate of the cleaning system is 3.22%,and the cleaning rate is 95.67%.Compared to the conventional cyclone separation cleaning device,the loss rate is reduced by 2.17%and the cleaning rate is increased by 1.05%.This study can provide a reference for the optimal cleaning system design for rape combine harvesters.

关键词： agricultural engineering cleaning system cyclone separation cylinder sieve rapeseed combine harvester

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Resurgence of dengue in the Philippines

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World Journal of Virology 2024年第3期13卷 7-9页

作者： Jasmine s Interior Kyrsten Jannae J Bigay Remigo Angelo A Iringan Mary Beth F Tanco st.luke's Medical Center College of Medicine-William H.Quasha Memorial Quezon 1112Philippines

The coronavirus disease 2019(COVID-19)pandemic has significantly influenced the epidemiological landscape of various infectious diseases such as *** is an endemic disease in the Philippines,which showed a significant de-cline in the number of cases beginning in March 2020 due to the stringent public health measures implemented to curb COVID-19 ***,the easing of these restrictions subsequently led to a resurgence in dengue cases,as reported by the World Health Organization,with a notable increase compared to previous *** the country navigates towards a post-pandemic phase,addressing the resurgence of dengue requires sustained efforts in vector control,surveillance,and healthcare *** article underscores the critical need for collab-orative efforts among stakeholders to mitigate the resurgence of dengue while managing the ongoing recovery from the COVID-19 pandemic.

关键词： Dengue Dengue fever COVID-19 Pandemic sARs-CoV-2 Philippines

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seasonal changes in Hermit Thrush (Catharus guttatus) song syntax

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Avian Research 2024年第2期15卷 172-179页

作者： sean P.Roach luke C.McLean Jeff W.MacLeod Leslie s.Phillmore Psychology Department University of New Brunswick Saint John100 Tucker Park RoadSaint JohnNBCanada Department of Psychology and Neuroscience Dalhousie University1355 Oxford StHalifaxNSB3H 4J1Canada

In many songbird species,birdsong features phonological syntax,meaning that the units within their vocal se-quences are ordered in a non-random way that adheres to a *** such syntactical patterns have been richly described in many species,comparatively little is known about how those patterns contribute to song achieving its important *** each of song’s main functions,territorial defense and mate attraction,evidence of a role for syntax is *** species for which syntax has been thoroughly described is the Hermit Thrush(Catharus guttatus),which presents song types from their repertoires in a semi-predictable order and,in doing so,rapidly cycle up and down the frequency *** objective of the present study was to explore the importance of song syntax in the Hermit Thrush through a within-subject examination of how measures of syntax,such as the predictability of song type order within song sequences,shift over the breeding *** hypothesized that,if such syntactical characteristics are important to breeding behaviour,they would be most prominent at the start of the breeding season when activity associated with territory establishment and mate attraction is most *** revealed that,as predicted,the rigidness of song type ordering within se-quences was highest at the start of the season and declined *** song type sequences were most predictable at the vitally important early part of the breeding season fit our hypothesis that this aspect of song syntax is important to song’s functions related to territory establishment and/or mate *** work will clarify whether that role relates to one of song’s two main functions or serves song transmission in some broader way.

关键词： Birdsong Hermit Thrush seasonal change stereotypy syntax

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Wood anatomy chronologies of scots pine in the foothills of the Western sayan(siberia)

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Journal of Forestry Research 2024年第3期35卷 13-27页

作者： Elena A.Babushkina Dmitry R.Dergunov Mikhail s.Zharkov Liliana V.Belokopytova Dina F.Zhirnova Bao Yang Jingjing Liu Xiaomei Peng Eugene A.Vaganov Khakass Technical institute Siberian Federal UniversityAbakan 655017Russia institute of Ecology and Geography Siberian Federal UniversityKrasnoyarsk 660036Russia Mathematical Methods and IT Department Siberian Federal UniversityKrasnoyarsk 660036Russia Key Laboratory of Desert and Desertification Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000People's Republic of China school of Geographic and Oceanographic sciences Nanjing UniversityNanjing 210093People's Republic of China Department of Dendroecology V.N.Sukachev Institute of ForestSiberian Branch of the Russian Academy of ScienceKrasnoyarsk 660036Russia

Recent methodological advances in quantitative wood anatomy have provided new insights into the climatic responses of radial growth at the scale of cell structure of tree rings. This study considered long-term chronologies of tracheid measurements, indexed by a novel approach to separate their specific climatic responses from signal recorded in cell production(closely reflected in tree-ring width). To fill gaps in understanding the impact of climate on conifer xylem structure, scots pine(Pinus sylvestris L.)trees > 200 years old were selected within the forest-steppe zone in southern siberia. such habitats undergo mild moisture deficits and the resulting climatic regulation of growth processes. Mean and maximum values of cell radial diameter and cell wall thickness were recorded for each tree *** a low level of climatogenic stress, components of cell chronologies independent of cambial activity were separated to obtain significant climatic signals revealing the timing of the specific stages of tracheid differentiation. Cell expansion lasted from mid-April to July and was impacted similarly to tree-ring width(stimulated by precipitation and stressed by heat), maximum cell size formed late June. A switch in the climatic responses of mean anatomical traits indicated transition to latewood in mid-July. secondary wall deposition lasted until mid-september, suppressed by end of season temperatures. Generally, anatomical climatic responses were modulated by a less dry May and september compared with summer months.

关键词： Quantitative wood anatomy Cell radial size Cell wall thickness Pinus sylvestris Climatic response

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speed and surface steepness affect internal tibial loading during running

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Journal of sport and Health science 2024年第1期13卷 118-124页

作者： Hannah Rice Markus Kurz Patrick Mai Leon Robertz Kevin Bill Timothy R.Derrick steffen Willwacher Department of Physical Performance Norwegian School of Sport SciencesOslo 0806Norway sports Tech Research Centre Mid Sweden UniversityÖstersund SE-83125Sweden Department of Mechanical and Process Engineering Offenburg University of Applied SciencesOffenburg 77652Germany institute of Biomechanics and Orthopaedics German Sport University CologneCologne 50933Germany Department of Kinesiology Iowa State UniversityAmesIA 50011USA

Background:Internal tibial loading is influenced by modifiable factors with implications for the risk of stress *** encounter varied surface steepness(gradients)when running outdoors and may adapt their speed according to the *** study aimed to quantify tibial bending moments and stress at the anterior and posterior peripheries when running at different speeds on surfaces of different ***:Twenty recreational runners ran on a treadmill at 3 different speeds(2.5 m/s,3.0 m/s,and 3.5 m/s)and gradients(level:0%;uphill:+5%,+10%,and+15%;downhill:-5%,-10%,and-15%).Force and marker data were collected synchronously *** moments were estimated at the distal third centroid of the tibia about the medial-lateral axis by ensuring static equilibrium at each 1%of *** was derived from bending moments at the anterior and posterior peripheries by modeling the tibia as a hollow ***-way repeated-measures analysis of variance were conducted using both functional and discrete statistical ***:There were significant main effects for running speed and gradient on peak bending moments and peak anterior and posterior *** running speeds resulted in greater tibial *** uphill at+10%and+15%resulted in greater tibial loading than level *** downhill at-10%and-15%resulted in reduced tibial loading compared to level *** was no difference between+5%or-5%and level ***:Running at faster speeds and uphill on gradients≥+10%increased internal tibial loading,whereas slower running and downhill running on gradients≥-10%reduced internal *** running speed according to the gradient could be a protective mechanism,providing runners with a strategy to minimize the risk of tibial stress injuries.

关键词： Bending moments Gradient Musculoskeletal modeling Overuse injury Tibial stress Training factors

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Disentangling the effects of management and climate change on habitat suitability for saproxylic species in boreal forests

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Journal of Forestry Research 2024年第2期35卷 121-133页

作者： Ellinoora Ekman María Triviño Clemens Blattert Adriano Mazziotta Maria Potterf Kyle Eyvindson Department of Biological and Environmental science University of JyvaskylaP.O.Box 3540014 JyvaskylaFinland institute for Atmospheric and Earth system Research(INAR)/Physics Faculty of ScienceUniversity of HelsinkiP.O.Box 6800014 HelsinkiFinland school of Resource Wisdom University of JyvaskylaP.O.Box 3540014 JyvaskylaFinland Natural Resources institute Finland(luke) Latokartanonkaari 900790 HelsinkiFinland Ecosystem Dynamics and Forest Management Group Technical University of MunichHans‑Carl‑Von‑Carlowitz‑Platz 285354 FreisingGermany Faculty of Environmental sciences and Natural Resource Management Norwegian University of Life SciencesP.O.Box 50031433ÅsNorway

Forest degradation induced by intensive forest management and temperature increase by climate change are resulting in biodiversity decline in boreal *** forest management and high-end climate emission scenarios can further reduce the amount and diversity of deadwood,the limiting factor for habitats for saproxylic species in European boreal *** magnitude of their combined effects and how changes in forest management can affect deadwood diversity under a range of climate change scenarios are poorly *** used forest growth simulations to evaluate how forest management and climate change will individually and jointly affect habitats of red-listed saproxylic species in *** simulated seven forest management regimes and three climate scenarios(reference,RCP4.5 and RCP8.5)over 100 *** regimes included set aside,continuous cover forestry,business-as-usual(BAU)and four modifications of *** suitability was assessed using a speciesspecific habitat suitability index,including 21 fungal and invertebrate species groups.“Winner”and“loser”species were identified based on the modelled impacts of forest management and climate change on their habitat *** found that forest management had a major impact on habitat suitability of saproxylic species compared to climate *** suitability index varied by over 250%among management regimes,while overall change in habitat suitability index caused by climate change was on average only 2%.More species groups were identified as winners than losers from impacts of climate change(52%–95%were winners,depending on the climate change scenario and management regime).The largest increase in habitat suitability index was achieved under set aside(254%)and the climate scenario RCP8.5(>2%),while continuous cover forestry was the most suitable regime to increase habitat suitability of saproxylic species(up to+11%)across all climate change *** results show that close-to-na

关键词： Biodiversity simulations Finland Forest planning Habitat suitability Deadwood

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