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Enhanced air-coupled impact echo technique by phase analysis of signals from multiple sensors

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 297-310页

作者： Najjiya Almallah Nenad Gucunski new Jersey Department of Transportation New Jersey 08625USA Department of Civil&Environmental Engineering Rutgers University-New BrunswickNJ 08854USA

This paper presents an air-coupled impact echo(IE)technique that relies on the phase spectrum of the collected data to find the frequencies corresponding to the reflections from *** proposed technique takes advantage of the fact that the IE compression wave is not a propagating wave,but it is the 1st order symmetrical(S1)mode Lamb wave at zero group velocity(S1-ZGV).Therefore,it searches the phase spectra of the data collected by multiple sensors to locate the frequency corresponding to the lowest phase *** a result,the technique reduces the effect of propagating waves,including the direct acoustic wave and ambient *** is named the Constant Phase IE(CPIE).The performance of the CPIE is experimentally compared with the regular amplitude spectrum-based IE technique and two other multisensor IE *** CPIE shows a performance advantage,especially in a noisy environment.

关键词： nondestructive testing(NDT) nondestructive evaluation(NDE) bridge inspection bridge evaluation impact echo bridge delamination concrete bridge deck air-coupled sensing MEMS

The modulatory effect of oolong tea polyphenols on intestinal flora and hypothalamus gene expression in a circadian rhythm disturbance mouse model

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Food Science and Human Wellness 2024年第2期13卷 748-764页

作者： Ruonan Yan Chi-Tang Ho Yanan Liu Shengnan Zhan Zufang Wu Xin Zhang Department of Food Science and Engineering Ningbo UniversityNingbo 315211China Department of Food Science Rutgers UniversityNew BrunswickNew Jersey 08901USA

The interaction between host circadian rhythm and gut microbes through the gut-brain axis provides new clues for tea polyphenols to improve host *** present research showed that oolong tea polyphenols(OTP)improved the structural disorder of the intestinal flora caused by continuous darkness,thereby modulating the production of metabolites related to pyruvate metabolism,glycolysis/gluconeogenesis,and tryptophan metabolism to alleviate the steady-state *** fecal microbiota transplantation from the OTP group,the single-cell transcriptomic analysis revealed that OTP significantly increased the number of hypothalamus cell clusters,up-regulated the number of astrocytes and fibroblasts,and enhanced the expression of circadian rhythm genes Cry2,Per3,Bhlhe41,Nr1d1,Nr1d2,Dbp and Rorb in hypothalamic *** results confirmed that OTP can actively improve the intestinal environmental state as well as internal/peripheral circadian rhythm disorders and cognitive impairment,with potential prebiotic functional characteristics to notably contribute to host health.

关键词： Gut microbiota Circadian rhythm Oolong tea polyphenols Single-cell sequencing Metabolism

Regular types and order of vanishing along a set of non-integrable vector fields

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Acta Mathematica Sinica,English Series 2024年

作者： Xiaojun HUANG Wanke YIN Department of Mathematics Rutgers UniversityNew Brunswick School of Mathematics and Statistics Wuhan University

This paper has two parts. We first survey recent efforts on the Bloom conjecture which still remains open in the case of complex dimension at least 4. Bloom’s conjecture concerns the equivalence of three regular types. There is a more general important notion, called the singular D’Angelo type (or simply, D’Angelo type). While the finite D’Angelo type condition is the right one for the study of local subelliptic estimates for Kohn’s ■-Neumann problem, regular types are important as their finiteness gives the global regularity up to the boundary of solutions of Kohn’s ■-Neumann *** the second part of the paper, we provide a proof of a seemingly elementary but a truly fundamental property (Theorem 2.2 or its CR version Theorem 2.5) on the vanishing order of smooth functions along a system of non-integrable vector fields. A special case, Corollary 2.6, of Theorem 2.5had appeared in a paper of D’Angelo. A main goal in this part is to provide proofs for these results for the purpose of future references. Our arguments are based on a deep normalization theorem for a system of non-integrable vector fields due to Helffer-Nourrigat, as well as its late generalization by Boauendi-Rothschild.

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Gluing Affine Vortices

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Acta Mathematica Sinica,English Series 2024年第1期40卷 250-312页

作者： Guang Bo XU Department of Mathematics Rutgers UniversityHill Center-Busch Campus 110 Frelinghuysen RoadPiscatawayNJ 08854-8019USA

We provide an analytical construction of the gluing map for stable affine vortices over the upper half plane with the Lagrangian boundary *** result is a necessary ingredient in studies of the relation between gauged ... 详细信息

关键词： Affine vortices gauged linear sigma model adiabatic limit symplectic reduction

Piperine regulates the circadian rhythms of hepatic clock gene expressions and gut microbiota in high-fat diet-induced obese rats

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Food Science and Human Wellness 2024年第3期13卷 1617-1627页

作者： Weiyun Zhang Chi-Tang Ho Wenlian Wei Jie Xiao Muwen Lu Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods College of Food ScienceSouth China Agricultural UniversityGuangzhou 510642China Department of Food Science Rutgers UniversityNew Brunswick 08901USA

The interplay between the host circadian clock and microbiota has significant influences on host metabolism processes,and circadian desynchrony triggered by high-fat diet(HFD)is closely related to metabolic *** this study,the modulatory effects of piperine(PIP)on lipid metabolism homeostasis,gut microbiota community and circadian rhythm of hepatic clock gene expressions in obese rats were *** Sprague-Dawley(SD)rats were fed with normal diet(ND),HFD and HFD supplemented with PIP,*** 9 weeks,rats were sacrificed with tissue and fecal samples collected for circadian *** showed that chronic PIP administration ameliorated the obesity-induced alterations in lipid metabolism and dysregulation of hepatic clock gene expressions in obese *** gut microbial communities studied through 16S rRNA sequencing showed that PIP ameliorated the imbalanced nicrobiota and recovered the circadian rhythm of Lactobacillaceae,Desulfovibrionaceae,Paraprevotellaceae,and *** fecal metabolic profiles indicated that 3-dehydroshikimate,cytidine and lithocholyltaurine were altered,which were involved in the amino acid and fatty acid metabolism *** findings could provide theoretical basis for PIP to work as functional food to alleviate the lipid metabolism disorder,circadian rhythm misalignment,and gut microbiota dysbiosis with wide applications in the food and pharmaceutic industries.

关键词： Piperine Circadian clock Obesity Gut microbiota

Oxygen heterocyclic compounds(OHCs) in lemon oils are important markers in targeted HPLC analyses for authentication

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Food Science and Human Wellness 2024年

作者： Siyu Liu Shiming Li Chi-Tang Ho Department of Food Science rutgers university New Brunswick College of Biology and Agricultural Resources Huanggang Normal university

Lemon oils are broadly used as flavoring agents in beverages， foods， cosmetics and pharmaceuticals， yet the adulteration of natural， particularly cold pressed lemon oils is very common in the industry due to its unmet demand and high cost. Nowadays， most quality control (QC) analysis of lemon oils is conducted by gas chromatography (GC) analysis， which is far from a reliable method. Oxygen heterocyclic compounds (OHCs) in non-volatile fraction are gaining increasing attention in authentication process because of the nearly finger-printing profiles of OHCs in cold pressed citrus essential oils. Our goal in this study was to identify OHCs using high performance liquid chromatography (HPLC) in lemon oils， establish OHC profiles， perform stepwise logistic regression analysis (SLRA) and build effective predicting model and further determine adulterated lemon oils by referencing the OHC profiles and established models. After HPLC analyses， profiling and SLRA modeling of 154 OHCs samples of industrial lemon oils， we found that the combination of isopimpinellin and total OHC concentration are essential and robust predictors to differentiate authentic samples from adulterated lemon oils with a success rate of 98% from the 5-fold cross validation. This study provided a reliable and efficient method in determining the authenticity of lemon oils.

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Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 203-204页

作者： Vishal Singh Arnab Choudhury Hyung Jin Ahn Department of Pharmacology Physiology and NeurosciencesRutgers-New Jersey Medical SchoolNewarkNJUSA Brain Health Institute Rutgers UniversityPiscatawayNJUSA

Alzheimer’s disease(AD)stands out as the primary manifestation of age-related dementia,portraying a chronic neurodegenerative disorder distinguished by the accumulation of fibrillar amyloid-β(Aβ)plaques and neurofibrillary tangles of hyperphosphorylated ***,from a clinical standpoint,AD presents itself as a complex condition with a spectrum of dysfunctions rather than a singular pathological *** often-overlooked aspect of the disease is the presence of extensive cerebrovascular abnormalities,given that the majority of AD patients experience altered cerebral blood flow,damaged vasculature,increased microinfarcts and *** models of AD further support this observation,showing cerebrovascular dysfunction such as impaired cerebral blood flow and altered cerebrovascular reactivity(Tataryn et al.,2021;Gareau et al.,2023).

关键词： cerebrovascular dysfunction Alzheimer

Do tensile and shear forces exerted on cells influence mechanotransduction through stored energy considerations?

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BIOCELL 2024年第4期48卷 525-540页

作者： FREDERICK H.SILVER TANMAY DESHMUKH Department of Pathology and Laboratory Medicine Robert Wood Johnson Medical SchoolRutgersThe State University of New JerseyPiscatawayNJ 08854USA OptoVibronex LLC.Ben Franklin Tech PartnersBethlehemPA 18015USA

All tissues in the body are subjected externally to gravity and internally by collagenﬁbril and cellular retractive forces that create stress and energy equilibrium required for *** involves mechanical work(force through a distance)and energy storage as kinetic and potential *** leads to changes in cell mitosis or apoptosis and the synthesis or loss of tissue *** involves the application of energy directly to cells through integrin-mediated processes,cell-cell connections,stretching of the cell cytoplasm,and activation of the cell nucleus via yes-associated protein(YAP)and transcriptional coactivator with PDZ-motif(TAZ).These processes involve numerous complexes,intermediate molecules,and multiple *** pathways have been identiﬁed from research studies on vertebrate cell culture and from studies in *** pathways involve mechanosensors and other molecules that activate the *** review discusses the mitogen-activated protein kinase(MAPK)family,Hippo,Hedgehog,and Wingless-related integration site(WNT)/βcatenin signaling *** mediators covered includeβcatenin,ion channels,growth factors,hormone receptors,members of the Ras superfamily,and components of the linker of nucleoskeleton and cytoskeleton(LINC)***,the interrelationship among the different pathways remains to be clariﬁ***-mediated mechanotransduction involves direct tensile loading and energy applied to the cell membrane via collagenﬁbril *** energy is transferred between cells by stretching the cell-cell connections involving cadherins and the WNT/βcatenin *** alterations induce changes in intracellular events in the cytoskeleton and nuclear skeleton caused by the release of YAP and *** coactivators then penetrate through the nuclear pores and inﬂuence nuclear cell *** in the balance of forces and energy applied to cells and tissues is hypothesized to shift th

关键词： MAPK family Hippo Hedgehog WNT pathway βcatenin Ion channels Growth factor receptors Hormone receptors Ras superfamily LINC complex Collagen Cadherins

Bioactive phytochemicals and associated multifunctional health-promoting effects of Polygonati Rhizoma

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Food Science and Human Wellness 2024年

作者： Shuzhen Wang Feng He Yunli Xiao Fu Xiang Lan Lu Wei Wu Chi-Tang Ho Shiming Li College of Biology and Agricultural Resources Huanggang Normal university School of Computer and Information Technology Beijing Jiaotong university Department of Food Science rutgers university New Brunswick

Polygonati Rhizoma， a functional food and a traditional Chinese medicine broadly used in China and several Southeast Asia countries， possesses effective health-promoting activities. Prepared from three plants in Polygonatum family (P. kingianum， P. sibiricum， and P. cyrtonema)， Polygonati Rhizoma has drawn increasing attention due to its remarkable immune-enhancing and metabolic regulatory activities in recent years. In this review， we summarized the updated research of chemical constituents and biological activities of Polygonati Rhizoma， especially the metabolic regulation， immunomodulatory effects， and anti-fatigue activities， aiming to provide a comprehensive understanding， broaden the usage and promote more in-depth exploration of Polygonati Rhizoma as a functional food.

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