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Current state of the art imaging approaches for colorectal liver metastasis

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hepatobiliary Surgery and Nutrition 2020年第1期9卷 35-48页

作者： Bita hazhirkarzar Pegah Khoshpouri Mohammadreza Shaghaghi Mounes Aliyari Ghasabeh Timothy M.Pawlik Ihab R.Kamel russell h.morgan department of radiology and radiological sciences Johns Hopkins University School of MedicineBaltimoreMDUSA department of Surgery The Ohio State UniversityWexner Medical CenterColumbusOHUSA

One of the most common cancers worldwide, colorectal cancer (CRC) has been associated with significant morbidity and mortality and therefore represents an enormous burden to the health care system. Recent advances in CRC treatments have provided patients with primary and metastatic CRC a better long-term prognosis. The presence of synchronous or metachronous metastasis has been associated, however, with worse survival. The most common site of metastatic disease is the liver. A variety of treatment modalities aimed at targeting colorectal liver metastases (CRLM) has been demonstrated to improve the prognosis of these patients. Loco-regional approaches such as surgical resection and tumor ablation (operative and percutaneous) can provide patients with a chance at long-term disease control and even cure in select populations. Patient selection is important in defining the most suitable treatment option for CRLM in order to provide the best possible survival benefit while avoiding unnecessary interventions and adverse events. Medical imaging plays a crucial role in evaluating the characteristics of CRLMs and disease resectability. Size of tumors, proximity to adjacent anatomical structures, and volume of the unaffected liver are among the most important imaging parameters to determine the suitability of patients for surgical management or other appropriate treatment approaches. We herein provide a comprehensive overview of current-state-of-the-art imaging in the management of CRLM, including staging, treatment planning, response and survival assessment, and post-treatment surveillance. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are two most commonly used techniques, which can be used solely or in combination with functional imaging modalities such as positron emission tomography (PET) and diffusion weighted imaging (DWI). Providing up-to-date evidence on advantages and disadvantages of imaging modalities and tumor assessment criteria, the current

关键词： Colorectal metastasis liver imaging tumor response

Role of transcatheter arterial embolization for massive bleeding from gastroduodenal ulcers

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World Journal of Gastroenterology 2009年第47期15卷 5889-5897页

作者： Romaric Loffroy Boris Guiu The russell h morgan department of radiology and radiological science Division of Cardiovascular and Interventional Radiology The Johns Hopkins Hospital 600 North Wolfe Street Blalock 545 BaltimoreMD 21287 United States Division of Vascular and Interventional radiology University of Dijon School of Medicine Bocage Teaching Hospital 2 bd du Maréchal de Lattre de Tassigny BP 77908 21079 Dijon Cedex France

Intractable bleeding from gastric and duodenal ulcers is associated with significant morbidity and mortality. Aggressive treatment with early endoscopic hemostasis is essential for a favourable outcome. In as many as 12%-17% of patients,endoscopy is either not available or unsuccessful. Endovascular therapy with selective catheterization of the culprit vessel and injection of embolic material has emerged as an alternative to emergent operative intervention in high-risk patients. There has not been a systematic literature review to assess the role for embolotherapy in the treatment of acute upper gastrointestinal bleeding from gastroduo-denal ulcers after failed endoscopic hemostasis. here,we present an overview of indications,techniques,and clinical outcomes after endovascular embolization of acute peptic-ulcer bleeding. Topics of particular relevance to technical and clinical success are also discussed. Our review shows that transcatheter arterial embolization is a safe alternative to surgery for massive gastroduodenal bleeding that is refractory to endoscopic treatment,can be performed with high technical and clinical success rates,and should be considered the salvage treatment of choice in patients at high surgical risk.

关键词： Peptic ulcer Massive bleeding Endoscopy Angiography Embolization

Prevalence of unsuspected thyroid nodules in adults on contrast enhanced 16-and 64-MDCT of the chest

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World Journal of radiology 2012年第7期4卷 311-317页

作者： Sameer Ahmed Pamela T Johnson Karen M horton Atif Zaheer Saline Tsai Elliot K Fishman russell h morgan department of radiology and radiological science Johns Hopkins Hospital Baltimore MD 21212 United States

AIM: To determine the prevalence of unsuspected thyroid nodules on contrast enhanced 16and 64-modified discrete cosine transform (MDCT) of the chest, in a population of adult outpatients imaged for indications other than thyroid disease. METhODS: This retrospective study involved review of intravascular contrast-enhanced MDCT scans of the chest from 3077 consecutive adult outpatients, to identify unsuspected thyroid nodules. Exclusion criteria included history of thyroid cancer, known thyroid nodules or thyroid disease and risk factors for thyroid cancer, as evidenced by their medical records. One of 9 radiologists recorded number of nodules, location and bidirectional measurement of largest nodule, as well as amount of thyroid visualized on the chest computed tomography (CT). Presence of nodule was correlated with age, gender, race and percentage of thyroid imaged. RESULTS: A total of 2510 (2510/3077 or 81.6%) study subjects were included in the data analysis; among them,one or more nodules were identified in 629 subjects (629/2510 or 25.1%), with 242 (242/629 or 38.5%) having multiple nodules. Patients with nodule(s) were significantly older than those without (64 ± 13 years vs 58 ± 14 years, P h presence of nodule(s) (373/1222 or 30.5% vs 256/1288 or 19.9%, P having multiple nodules (167/373 or 44.8%) compared to men (75/256 or 29.3%, P he majority of nodules (427/629 or 67.9%) were less than 1 cm. CONCLUSION: This retrospective review revealed a prevalence of 25.1% for unsuspected thyroid nodules on contrast-enhanced chest CT.

关键词： Thyroid nodule Thyroid cancer Multidetector cosine transform Incidental finding Chest computed tomography

Spectrum of magnetic resonance imaging findings in congenital lumbar spinal stenosis

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World Journal of Clinical Cases 2014年第12期2卷 883-887页

作者： Theodoros Soldatos Majid Chalian Shrey Thawait Alan J Belzberg John Eng John A Carrino Avneesh Chhabra russell h morgan department of radiology and radiological science the Johns Hopkins Hospital Baltimore MD 21287 United States department of Neurosurgery the Johns Hopkins Hospital Baltimore MD 21287 United States department of radiology and Orthopaedic Surgery University of Texas Southwestern Medical Center Dallas TX 75390-9178 United States

AIM: To investigate whether congenital lumbar spinal stenosis(CLSS) is associated with a specific degenerative changes of the lumbar spine. METhODS: The lumbar spine magnetic resonance imaging studies of 52 subjects with CLSS and 48 control subjects were retrospectively evaluated. In each examination, the five lumbar levels were assessed for the presence or absence of circumferential or shallow annular bulges, annular tears, anterior or posterior disc herniations, epidural lipomatosis, Schmorl's nodes,spondylolisthesis, pars defects, and stress reactions of the posterior vertebral elements. RESULTS: Compared to control individuals, subjects with CLSS exhibited increased incidence of circumferential and shallow annular bulges, annular tears, discherniations and spondylolisthesis(P h increased incidence of degenerative changes in specific osseous and soft-tissue elements of the lumbar spine.

关键词： Congenital lumbar spinal stenosis Magnetic resonance imaging Imaging findings Degenerative changes Low back pain

高级影像检查在老年人X线隐匿性髋部骨折中的应用:系统综述及荟萃分析

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国际医学放射学杂志 2020年第6期 731-732页

作者：董力宁 A.haj-Mirzaian J.Eng R.Khorasani A.S.Raja A.S.Levin S.E.Smith The russell h.morgan department of radiology and radiological science Johns Hopkins University School of Medicine

摘要临床上怀疑有髋部骨折的老年病人中,X线摄影未发现但需行手术治疗的髋部骨折(即外科髋部骨折)的总发生率仍不清楚。此外,对这些病人进一步行高级影像检查的

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他汀类药物与表现为heberden结节的膝关节骨性关节炎的关系：来自于OAI的研究结果

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国际医学放射学杂志 2020年第1期 107-108页

作者： A. haj-Mirzaian B. Mohajer A. Guermazi P.G. Conagham J.A.C. Lima M.J. Blaha 邹明珠 department of Musculoskeletal radiology Russell H.Morgan Department of Radiology and Radiological Science Johns Hopkins University School of Medicine

他汀类药物对于膝关节骨性关节炎(OA)影像学表现的确切影响,以及OA病人对他汀类药物的疗效反应特征尚不明确。目的探讨他汀类药物的应用对于依据heber-

关键词：他汀类药物 heberden 研究结果骨性关节炎 OAI

表观扩散系数鉴别浆液性和黏液性胰腺囊性肿瘤的价值

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国际医学放射学杂志 2019年第6期 742-743页

作者： P.Pandey A.Pandey N.Shao F.N.Varzaneh M.A.Ghasabeh M.Zharghampour 杨琳 russell h.morgan department of radiology and radiological sciences Central Radiology Johns Hopkins University School of Medicine

摘要目的评估MR扩散加权成像(DWI)用于鉴别浆液性与黏液性胰腺囊性肿瘤(PCN)的价值。方法纳入117例PCN≥10 mm的病人。3名阅片者在是否使用表观扩散系

关键词：胰腺囊性肿瘤黏液性浆液性扩散系数

偶然发现的胰腺囊性肿瘤的随访：基线MRI和CT的特征能预测囊肿的生长吗？

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国际医学放射学杂志 2019年第6期 728-729页

作者： P.Pandey A.Pandey Y.Luo M.A.Ghasabeh P.Khoshpouri S.Ameli 张瀚 russell h.morgan department of radiology and radiological sciences Johns Hopkins University School of Medicine

摘要目的使用修订的美国放射学会(ACR)建议评估偶然检测到的胰腺囊性肿瘤(PCN)在长期影像学随访中的增长情况,并评估基线成像的影像特征与生长之间的关联。

关键词：胰腺囊性肿瘤 CT MRI

心脏CT评估致心律失常性右心室型心肌病的心外脂肪分布

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国际医学放射学杂志 2019年第1期 110-111页

作者： M.A.Ghasabeh A.S.J.M.Te Riele C.A.James h.S.Vincent Chen C.Tichnell B.Murray 刘会娜 The russell h. morgan department of radiology and radiological sciences Johns Hopkins University School of Medicine

摘要目的比较致心律失常性右心室型心肌病(ARVD/C)病人和健康对照组的心外膜脂肪差异。材料与方法回顾性对比研究2008年1月—2015年7月期间行心脏CT检查

关键词：心肌病心律失常右心室 CT