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The natural history of flail chest injuries

Chinese Journal of Traumatology 2017年第5期20卷 293-296页

作者： Kamil Naidoo Layth Hanbali Peter Bates royal London Hospital. Whitechapel London UK

Purpose： Flail chest （FC） injuries represent a significant burden on trauma services because of its high morbidity and mortality. Current gold standard conservative management strategies for FC, are now being challenged by renewed interest in surgical rib fixation. This retrospective epidemiological study sets out to evaluate FC patients, and quantify the natural history of this injury by studying the injury patterns, epidemiology and mortality of patients sustaining FC injuries admitted to a major trauma centre （MTC）. Methods： A retrospective cohort analysis has been conducted at an MTC with full trauma service. All patients （age 〉 16 years） sustaining FC were included. Patient demographics, injury characteristics and inpatient stay information were extracted. Results： Two hundred and ninety-three patients were identified, with a mean injury severity score （ISS） of 28.9 （range 9-75）, average age of 56.1 years （range of 16-100）, and a male predominance （78%）. Road traffic accidents accounted for 45% （n = 132） of injuries, whilst 44% were fall or jump from height （n = 129）. Associated lung contusion was present in 133 patients （45%） while 76% of patients were found to have 5 or more ribs involved in the flail segment （n = 223） with 96% （n = 281 ） having a unilateral FC. Inpatient treatment was required 19.9 days （range 0-150 days） with 59% of patients （n = 173） requiring intensive care unit （ICU） level care for 8.4 days （range 1-63） with 61.8% requiring mechanical ventilation （n = 107） for 10.5 days （range 1-54）, and Z8g underwent rib fixation with rib plates （n = 23）. The mortality rate was found to be 14% （n = 42）. A non-significant trend towards improved outcomes in the conservative group was found when compared with the fixation group; ventilation days （6.94 vs 10.06, p = 0.18） intensive treatment unit （ITU） length of stay （LOS）（12.56 vs 15.53, p = 0.28） and hospital LOS （32.62 vs 35.24, p = 0.69）. Conclusion： This study has successfully described the natural hi

关键词： Flail chest Natural history Epidemiology Rib plates

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A Simulation of Signal Collisions over the North Atlantic for a Spaceborne ADS-B Receiver Using Aloha Protocol

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Positioning 2015年第3期6卷 23-31页

作者： Richard Van Der Pryt Ron Vincent Department of Physics Royal Military College of Canada Kingston Canada

Automatic Dependent Surveillance-Broadcast (ADS-B) is an air traffic surveillance system in which aircraft broadcast GPS position, velocity and status on 1090 MHz at random intervals between 0.4 and 0.6 seconds. ADS-B networks for air traffic monitoring have been implemented worldwide, but ground stations cannot be installed in oceanic regions, leaving these areas uncovered. A solution for tracking aircraft over the ocean is through the monitoring of ADS-B signals by using spaceborne receivers. The royal Military College of Canada has developed an ADS-B receiver that is scheduled to fly as a technology demonstrator on the canadian Advanced Nanospace eXperiment-7 (CanX-7) nanosatellite. The payload will collect ADS-B data over the North Atlantic that will be compared to truth data provided by air traffic services. A potential issue for the CanX-7 payload is signal collisions. The extended footprint of the satellite coverage means that a large number of aircraft may be in view at any one time, leading to ADS-B messages that arrive simultaneously at the receiver not being decoded. A simulation of CanX-7 passage over the operations area was carried out to calculate the probability of signal collisions. Using the Aloha Protocol, it was determined that the loss of information as a result of signal collisions is well within the standards of ground based radars used by air traffic system agencies.

关键词： ADS-B Satellite Air Traffic Control Aloha Protocol

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Remote sensing and analysis of tropical cyclones:Current and emerging satellite sensors

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Tropical Cyclone Research and Review 2023年第4期12卷 267-293页

作者： Lucrezia Ricciardulli Brian Howell Christopher R.Jackson Jeff Hawkins Joe Courtney Ad Stoffelen Sebastian Langlade Chris Fogarty Alexis Mouche William Blackwell Thomas Meissner Julian Heming Brett Candy Tony McNally Masahiro Kazumori Chinmay Khadke Maria Ana Glaiza Escullar Remote Sensing Systems Santa RosaCAUSA Joint Typhoon Warning Center Pearl HarborHawaiiUSA Global Ocean Associates(supporting NOAA/NESDIS STAR) AlexandriaVAUSA University of Wisconsin Cooperative Institute for Meteorological Satellite StudiesMadisonWIUSA Bureau of Meteorology PerthAustralia royal Netherlands Meteorological Institute(KNMI) De BiltNetherlands Tropical Cyclone/Regional Specialized Meteorological Center Meteo FranceReunionFrance canadian Hurricane Center(CHC) DartmouthNova ScotiaCanada University Brest CNRSIRDIfremerLaboratoire d’Oceanographie Physique et Spatiale(LOPS)IUEMBrestFrance MIT Lincoln Laboratory LexingtonMAUSA Met Office ExeterUK European Centre for Medium-Range Weather Forecasts ReadingUK Japan Meteorological Agency(JMA) TokyoJapan India Meteorological Department(IMD) New DelhiIndia Philippine Atmospheric Geophysical and Astronomical Services Administration(PAGASA)Diliman Quezon CityPhilippines

This article describes recent advances in the capability of new satellite sensors for observing Tropical Cyclones(TC)fine structure,wind field,and temporal *** article is based on a World Meteorological Organization(WMO)report prepared for the 10th International Workshop on Tropical Cyclones(IWTC),held in Bali in December 2022,and its objective is to present updates in TC research and operation every four *** we focus on updates regarding the most recent space-based TC observations,and we cover new methodologies and techniques using polar orbiting sensors,such as C-band synthetic aperture radars(SARs),L-band and combined C/X-band radiometers,scatterometers,and microwave imagers/*** additionally address progress made with the new generation of geostationary and small satellites,and discuss future sensors planned to be launched in the next *** then briefly describe some examples on how the newest sensors are used in operations and data assimilation for TC forecasting and research,and conclude the article with a discussion on the remaining challenges of TC space-based observations and possible ways to address them in the near future.

关键词： Tropical cyclones Surface wind Satellite sensors Operations

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A Simulation of Reflected ADS-B Signals over the North Atlantic for a Spaceborne Receiver

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Positioning 2016年第1期7卷 51-62页

作者： Richard Van Der Pryt Ron Vincent Department of Physics Royal Military College of Canada Kingston Canada

Automatic Dependent Surveillance-Broadcast (ADS-B) is an air traffic surveillance technology in which aircraft broadcast position, identification and status an average of 6.2 times per second on 1090 MHz. The royal Military College of Canada has developed an ADS-B receiver that is scheduled to fly as a technology demonstrator on the canadian Advanced Nanospace eXperiment-7 (CanX-7) nanosatellite. A signal propagation model was developed to determine the power level and number of signals that will be detected by CanX-7. Since the ADS-B messages are alternately transmitted from upper and lower antennas, both the direct and reflected signals were considered. A simulation using the model was run over the North Atlantic with aircraft data supplied by air traffic services and a satellite altitude of 800 km. Power at the receiver for reflected ADS-B signals ranged from -109.5 to -118 dBm depending on aircraft-satellite geometry and was approximately 18 dBm less than the direct path signal strength. With a sensitivity of -103 dBm, the CanX-7 ADS-B receiver should detect virtually all of the direct path signals while reflected signals are below the detection threshold. Although the reflected signals should not be a factor for the CanX-7 mission, they could be a consideration for a large operational satellite with a more sensitive receiver. The reception of both direct and reflected ADS-B signals from multiple aircraft could lead to signal collisions and subsequent loss of aircraft tracking information, particularly in coastal regions where there are additional sources of the 1090 MHz signal.

关键词： ADS-B Satellite Air Traffic Control Ocean Scattering

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Anatomical and Radiological Description of the Macaca fascicularis Spine in Comparison with the Human Spine

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Open Journal of Veterinary Medicine 2022年第12期12卷 171-186页

作者： Anant Krishnan Guneet Kaleka Scott Emerson Guy Sovak Heather Simmons Kevin Brunner Dane Schalk John Sledge Amber Hoggatt Shanker Nesathurai Department of Diagnostic Radiology Oakland University William Beaumont School of Medicine Auburn Hills USA Department of Diagnostic Radiology and Molecular Imaging Beaumont Hospital Royal Oak USA canadian Memorial Chiropractic College Toronto Canada Wisconsin National Primate Research Center Madison USA Lafayette Bone and Joint Clinic Lafayette USA Harvard medical School Boston USA Department of Physical Medicine and Rehabilitation Hamilton Health Sciences Corporation Hamilton Canada Division of Physical Medicine and Rehabilitation Michael G. DeGroote School of Medicine McMaster University Hamilton Canada

Background: This paper describes and displays the spinal radiological anatomy and associated pathology in a Macaca fascicularis and compares it to the spinal anatomy of humans. Animal models are commonly used in research. As compared to Macaca mulatta, the anatomy of M. fascicularis is less well described in the literature. Materials and methods: The authors anatomically reconstructed and reviewed the defleshed spine of a single adult M. fascicularis visually, radiographically, and with high resolution CT. Results: 7 cervical, 12 thoracic, 6 lumbar, 3 sacral, and 16 caudal vertebrae were identified. Similarities in the spine to humans were seen as well as differences such as the beaked anterior arch of C1, the anterior pointed lower lumbar vertebrae, the upward curved transverse processes, and presence of three sacral segments. Degenerative changes were seen at multiple locations similar to humans though most pronounced at T3-4. Conclusions: This paper addresses the normal spinal anatomy and degenerative changes in an adult M. fascicularis and compares it to humans.

关键词： Macaca Fascicularis Macaques Spine Anatomy Radiology CT Comparative Study Computed Tomography

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PTD-OD-HA融合蛋白对bcr/abl阳性细胞凋亡的影响

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肿瘤 2010年第4期30卷 267-271页

作者：黄峥兰季茂胜袁颖黄世峰刘钉宾曾建明温健萍冯文莉重庆医科大学临床血液学教研室临床检验诊断学教育部重点实验室重庆400016 重庆医科大学附属第一医院普外科重庆400016 canadian Blood services Hamilton ON L8S 1 H8 Canada

目的:研究含有蛋白转导域(protein transduction domain,PTD)、寡聚化结构域(oligomerization domain,OD)和HA标签的PTD-OD-HA融合蛋白对几种bcr/abl阳性细胞株细胞凋亡的影响。方法:将前期制备的PTD-OD-HA蛋白作用于几种bcr/abl阳性细胞后,应用FCM法、DNA梯度电泳(DNAladder)和透射电子显微镜检测细胞凋亡,RT-PCR和Western印迹法检测凋亡相关基因bax、bcl-2的mRNA和蛋白水平变化。结果:FCM法检测发现,PTD-OD-HA能促进bcr/abl阳性细胞发生凋亡;DNA ladder实验检测发现,PTD-OD-HA作用后BaF3-P210和K562细胞DNA电泳有梯状条带;透射电子显微镜观察发现,PTD-OD-HA作用后BaF3-P210细胞发生了凋亡;RT-PCR及Western印迹法检测显示,促凋亡基因bax的mRNA及蛋白水平增高,抗凋亡基因bcl-2的mRNA及蛋白水平降低。结论:PTD-OD-HA蛋白可以特异性诱发bcr/abl阳性细胞的凋亡。

关键词：白血病,髓样,慢性重组融合蛋白质类细胞凋亡融合蛋白类,bcr-abl

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以吡嗪酰胺用量作为评估结核病漏报的方法

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国际结核病与肺部疾病杂志 2002年第1期 38-41页

作者： J.H.van Loenhout-Rooyackers H.G.M.Leufkens Y.A.Hekster N.A.Kalisvaart 王海东 GGD Regio Nijmegen (Municipal Health services) Nijmegen Department of Pharmacoepidemiology and Pharmacotherapy Utrecht Institute for Pharmaceutical Sciences Utrecht University medical Centre Nijmegen St. Radboud Nijmegen royal Netherlands Tuberculosis Association (KNCV) Den Haag The Netherlands

目的:为了建立确认荷兰医生对活动性结核病报告的方法。方法:以服用化疗药物吡嗪酰胺作为结核病发生的标志。根据发给门诊病人吡嗪酰胺的每日剂量(DDD)来估计1994-1998年期间荷兰结核病患者的数量。DDD是一个测量的技术单位,不必须反... 详细信息

目的:为了建立确认荷兰医生对活动性结核病报告的方法。方法:以服用化疗药物吡嗪酰胺作为结核病发生的标志。根据发给门诊病人吡嗪酰胺的每日剂量(DDD)来估计1994-1998年期间荷兰结核病患者的数量。DDD是一个测量的技术单位,不必须反映推荐或者实际应用的剂量。通常它的主要指标是以具有正常器官功能成人的平均每日剂量为基础。荷兰医疗保险部(CVZ)的药物信息规划部门(GIP)提供DDD资料。以通报给荷兰结核病登记处(NTR)的结核病患者为基础,按照这些病人的体重计算他们应该服用多少吡嗪酰胺(测量DDD)。结果:按照GIP药房记录的DDD数量与通告给NTR计算出的DDD的数量只相差8％;登记的病人数应该是6889,而不是6349。结论:GIP和NTR测量的吡嗪酰胺用量的非常接近,有力地证明荷兰报告的结核病与应报告的疾病指标相符。这种方法使用简便并且值得在其他国家推广。

关键词： DDD 吡嗪酰胺结核病应报告疾病

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Infertility in China: Culture, society and a need for fertility counselling

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Asian pacific Journal of Reproduction 2019年第1期8卷 1-6页

作者： Shanna Logan Royce Gu Wen Li Shuo Xiao Antoinette Anazodo School of Women and Children's Health University of New South WalesSydneyAustralia Fertility and Research Centre Royal Hospital for WomenSydneyAustralia Kids Cancer Centre Sydney Children's HospitalSydneyAustralia Reproductive medical Center Shanghai Changzheng HospitalSecond Military Medical UniversityShanghaiChina Reproductive Health and Toxicology Laboratory Department of Environmental Health SciencesArnold School of Public HealthUniversity of South CarolinaColumbiaSC29208USA Nelune Comprehensive Cancer Centre Prince of Wales HospitalSydneyAustralia

With a high rate of infertility, it is important to understand the context of fertility and family planning in China, to inform the necessity of supportive care. A literature review was undertaken to explore the societal constructs informing perspectives of childbearing, family planning and infertility, alongside Chinese considerations of fertility treatments, including assisted reproductive technologies and fertility counselling. In China, childbearing attitudes and behaviours are shaped by tensions between traditional cultural values of the filial piety originating from Confucianism, the history of strict family planning policy, the recent termination of one-child policy and the socioeconomic circumstance. For infertile Chinese individuals, the inability to meet these childbearing expectations gives rise to significant pressure and consequent psychological distress, particularly depressive symptoms. Demographic factors such as gender, education, income and geographical location have been found to influence prevalence and degree of depression in infertile Chinese men and women. These difficulties are compounded by barriers of cultural acceptance, legislative restrictions and availability of resources for alternative options such as adoption and surrogacy. It is important that these fertility sociocultural factors are taken into consideration when assisting Chinese patients to access and utilise fertility treatment services.

关键词： China Infertility Family planning policy Sociocultural factors Fertility treatment Fertility counselling

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儿童精神卫生服务未能满足快速增长的需求--目前的危机就是对儿童有系统性歧视的明证

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英国医学杂志中文版 2018年第4期21卷 181-182页

作者： Dubicka, Bernadka Bullock, Tori royal Coll Psychiatrists Child & Adolescent Fac London England

自从绿皮书《每个儿童都重要》（Every Child Matters）发布以来已过了20年。20年前，英国政府发布这一报告旨在让儿童服务发生彻底转变，包括对儿童和青少年精神卫生服务的大力投资。

关键词：儿童精神卫生服务系统性歧视保健知识心理学

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Recreational Access Management Planning: Understanding Perceptions Regarding Public Forest Lands in SW Alberta

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Open Journal of Forestry 2015年第4期5卷 387-401页

作者： Rachelle L. Haddock Michael S. Quinn Miistakis Institute Mount Royal University Calgary Canada Faculty of Environmental Design University of Calgary Calgary Canada Institute for Environmental Sustainability Mount Royal University Calgary Canada

Management of recreational access on public forest lands is a complex issue of growing global importance. The provision of public recreation opportunities is part of the suite of ecological goods and services that must be considered by many forest managers. Effective access management is predicated on understanding the attitudes and perceptions of recreation users in order to predict and influence visitor behaviour and gauge the acceptance of new management strategies. Potential access management strategies vary given the nature of recreation activities and include: restricting the amount, type, and spatial distribution of use, visitor education, temporal restrictions and enhancing site durability. In this research we examined the views of recreation users on public lands in southwestern Alberta, Canada through implementation of an online survey (n = 945) with a focus on access management options. The results indicate a strong belief that the quality of the recreation experience is declining and that increased management and enforcement are required. More detailed analysis indicates that demographic and user-type variables strongly influence ideas about appropriate management. Forest managers need to engage with, understand, and respond to a wide variety of recreation user needs and preferences.

关键词： Forest Recreation Management Access Management Off-Highway Vehicles Non-Motorized Recreation Social Science of Natural Resource Management

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