检索结果-南通市图书馆

Pharmacological adjuvants for diabetic vitrectomy surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Methodology 2024年第4期14卷 84-90页

作者： Ramesh Venkatesh Chaitra Jayadev Vishma Prabhu Priyanka Gandhi Rupal Kathare Naresh K Yadav Ayushi Choudhary Jay Chhablani Department of Ophthalmology Narayana NethralayaBangalore 560010India Department of retina Narayana Nethralaya Eye InstituteBangalore 560010India Department of Vitreo retina Narayana NethralayaRetina ServSuper Specialty Eye Hospital and Post Graduate Institute of OphthalmologyBangalore 560010India Department of retina University of Pittsburg School of MedicinePittsburgPA 15213United States

Diabetic vitrectomy is a highly intricate surgical procedure performed during the advanced stages of diabetic retinopathy(DR).It is used to treat conditions such as tractional or combined retinal detachment,vitreous hemorrhage,and subhyaloid hemorrhage,which are all severe manifestations of proliferative *** results of the surgery are uncertain and *** surgery has made significant progress since the early stages of *** the past ten years,advancements in intravitreal pharmacotherapy have emerged,offering new possibilities to improve the surgical results for our *** the realm of medical terminology,an"adjunct"refers to a pharmaceutical or substance employed to aid or expedite the primary therapeutic intervention for a particular *** introduction has broadened the range of therapeutic choices that are accessible prior to,during,and following surgical *** review article will specifically analyze the pharmacological adjuncts used in diabetic vitrectomy surgery,with a focus on their role in facilitating or aiding specific steps of the *** implementation of this system of categorization offers benefits to the surgeon by allowing them to foresee potential difficulties that may occur during the surgical procedure and to choose the appropriate pharmacological agent to effectively tackle these challenges,thus enhancing surgical success rates.

关键词： Diabetic retinopathy Vitrectomy Intravitreal injections Anti-vascular endothelial growth factor Adjuvants Outcomes

retinal vascular morphological characteristics in diabetic retinopathy: an artificial intelligence study using a transfer learning system to analyze ultra-wide field images

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第6期17卷 1001-1006页

作者： Xin-Yi Deng Hui Liu Zheng-Xi Zhang Han-Xiao Li Jun Wang Yi-Qi Chen Jian-Bo Mao Ming-Zhai Sun Li-Jun Shen Center for Rehabilitation Medicine Department of OphthalmologyZhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)Hangzhou 310014Zhejiang ProvinceChina Department of Precision Machinery and Instrumentation University of Science and Technology of ChinaHefei 230026Anhui ProvinceChina Department of retina Eye Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

AIM:To investigate the morphological characteristics of retinal vessels in patients with different severity of diabetic retinopathy(DR)and in patients with or without diabetic macular edema(DME).METHODS:The 239 eyes of DR patients and 100 eyes of healthy individuals were recruited for the *** severity of DR patients was graded as mild,moderate and severe non-proliferative diabetic retinopathy(NPDR)according to the international clinical diabetic retinopathy(ICDR)disease severity scale classification,and retinal vascular morphology was quantitatively analyzed in ultra-wide field images using RU-net and transfer learning *** presence of DME was determined by optical coherence tomography(OCT),and differences in vascular morphological characteristics were compared between patients with and without ***:retinal vessel segmentation using RU-net and transfer learning system had an accuracy of 99%and a Dice metric of *** with the healthy group,the DR group had smaller vessel angles(33.68±3.01 vs 37.78±1.60),smaller fractal dimension(Df)values(1.33±0.05 vs 1.41±0.03),less vessel density(1.12±0.44 vs 2.09±0.36)and fewer vascular branches(206.1±88.8 vs 396.5±91.3),all Pretinal vessel segmentation system is used with 99%accuracy,thus providing with relatively satisfactory performance in the evaluation of quantitative vascular *** patients have a tendency of vascular occlusion and *** presence of DME does not compromise the integral retinal vascular pattern.

关键词： diabetic retinopathy vascular morphology deep learning ultra-wide field imaging diabetic macular edema

Bidirectional link between periodontitis and systemic inflammation in diabetic retinopathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第7期15卷 1651-1653页

作者： Prateek Nishant Sony Sinha Ranjeet Kumar Sinha Arvind Kumar Morya Department of Ophthalmology ESIC Medical CollegePatna 801103BiharIndia Department of Ophthalmology-Vitreo-retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatna 801507BiharIndia Department of Community Medicine Patna Medical CollegePatna 800004BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

Periodontitis is independently associated with numerous lifestyle *** patients have approximately threefold increased odds of periodontitis,which in turn increases the risk of systemic *** study by Thazhe Poyil et al is an effort to establish the inflammatory link between diabetic retinopathy(DR)and periodontitis based on the periodontal inflamed surface area in diabetic patients with and without *** further advance the study,we suggest refining the eligibility criteria to explicitly state the clinical correlates of periodontitis and DR,larger sample size and improved sampling methodology,matching of baseline characteristics of the two groups,as well as improved statistical approach and interpretation of the study *** of hemoglobin A1c(HbA1c)in studies comparing type 2 diabetes mellitus patients with DR of matched severity with and without periodontitis could provide a clearer picture of whether HbA1c level is indeed influenced by periodontitis.

关键词： Glucose intolerance Hyperglycemia Inflammation Research methodology Vision

Nutrition interventions and clinical outcomes of pregnant women with gestational diabetes mellitus: More than meets the eye

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第1期15卷 126-128页

作者： Sony Sinha Prateek Nishant Ranjeet Kumar Sinha Arvind Kumar Morya Ripunjay Prasad Department of Ophthalmology-Vitreo-retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatnaPatna 801507BiharIndia Department of Ophthalmology ESIC Medical CollegePatnaPatna 801103BiharIndia Department of Community Medicine Patna Medical CollegePatna 800004BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology RP Eye InstituteDelhi 110001DelhiIndia

In the retrospective study by Luo et al regarding clinical outcomes in gestational diabetes mellitus(GDM),the results are statistically significant in favour of the benefits of individualized nutrition interventions enumerated *** study has provided important evidence to improve maternal and child health in the Asian *** methods,however,appear to have considerable limi-tations,wherein the time point of diagnosis of GDM,severity of GDM,selection bias,compliance to therapy,important maternal covariates,observable microvascular abnormalities and the confounding effect of added insulin have not been *** have provided suggestions to improve the external validity of the study,including the use of Equator Network reporting guidelines and inclusion of overweight and obese patients in future studies.

关键词： Glucose intolerance Hyperglycemia Obesity Pregnancy Research methodology

Intraocular lens selection in diabetic patients:How to increase the odds for success

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第6期15卷 1199-1211页

作者： Arvind Kumar Morya Prateek Nishant Prasanna Venkatesh Ramesh Sony Sinha Aarti Heda Sarika Salodia Ripunjay Prasad Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology ESIC Medical CollegePatna 801113BiharIndia Department of Glaucoma and Research Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Department of Ophthalmology-Vitreo-retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatnaPatna 801507BiharIndia Department of Ophthalmology National Institute of OphthalmologyPune 411000MaharashtraIndia Department of Safety Global Medical SafetyLundbeckSingapore 307591Singapore Department of Ophthalmology RP Eye InstituteDelhi 110001India

The incidence of cataracts is significantly higher in diabetic individuals,particularly in younger age groups,with rates quadrupled in those under 65 and doubled in those over 65 compared to *** surgery in diabetic patients poses many challenges:Poor epithelial healing,decreased corneal sensitivity,increased central corneal thickness,decreased endothelial cell count,variable topography,poor pupillary dilatation,anterior capsular phimosis,posterior capsular opacification(PCO),chances of progression of diabetic retinopathy(DR),zonular weakness,and vitreous prolapse and diabetic macular *** of an appropriate intraocular lens(IOL)is crucial for visual rehabilitation and monitoring *** choice of IOL in diabetic cataract patients is a challenging ***-edge IOLs are favored for their capacity to mitigate PCO,whereas hydrophilic counterparts may incur calcification in the setting of proliferative *** advisability of premium IOLs for achieving spectacle independence warrants judicious evaluation,particularly in the presence of advanced *** IOL placement within the capsular bag is advocated to minimize postoperative *** preoperative assessment and informed patient counseling regarding IOL options are indispensable for optimizing surgical *** review article covers various aspects regarding the choice of IOLs in different case scenarios and complications in the diabetic population.

关键词： Diabetics Cataract Intraocular lens Diabetic retinopathy Diabetes mellitus

Construction and validation of a neovascular glaucoma nomogram in patients with diabetic retinopathy after pars plana vitrectomy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第4期15卷 654-663页

作者： Yi Shi Yan-Xin Zhang Ming-Fei Jiao Xin-Jun Ren Bo-Jie Hu Ai-Hua Liu Xiao-Rong Li Surgical retina Tianjin Key Laboratory of Retinal Functions and DiseasesTianjin Branch of National Clinical Research Center for Ocular DiseaseEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China Glaucoma Tianjin Key Laboratory of Retinal Functions and DiseasesTianjin Branch of National Clinical Research Center for Ocular DiseaseEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China Ocular Trauma Tianjin Key Laboratory of Retinal Functions and DiseasesTianjin Branch of National Clinical Research Center for Ocular DiseaseEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China

BACKGROUND Neovascular glaucoma(NVG)is likely to occur after pars plana vitrectomy(PPV)for diabetic retinopathy(DR)in some patients,thus reducing the expected *** the risk factors for NVG occurrence and building effective risk prediction models are currently required for clinical *** To develop a visual risk profile model to explore factors influencing DR after *** We retrospectively selected 151 patients with DR undergoing *** patients were divided into the NVG(NVG occurrence)and No-NVG(No NVG occurrence)groups according to the occurrence of NVG within 6 months after *** risk factors for postoperative NVG were screened by logistic regression.A nomogram prediction model was established using R software,and the model’s prediction accuracy was verified internally and externally,involving the receiver operator characteristic curve and correction *** After importing the data into a logistic regression model,we concluded that a posterior capsular defect,preoperative vascular endothelial growth factor≥302.90 pg/mL,glycosylated hemoglobin≥9.05%,aqueous fluid interleukin 6(IL-6)≥53.27 pg/mL,and aqueous fluid IL-10≥9.11 pg/mL were independent risk factors for postoperative NVG in patients with DR(P<0.05).A nomogram model was established based on the aforementioned independent risk factors,and a computer simulation repeated sampling method was used to internally and externally verify the nomogram *** area under the curve(AUC),sensitivity,and specificity of the model were 0.962[95%confidence interval(95%CI):0.932-0.991],91.5%,and 82.3%,*** AUC,sensitivity,and specificity of the external validation were 0.878(95%CI:0.746-0.982),66.7%,and 95.7%,*** A nomogram constructed based on the risk factors for postoperative NVG in patients with DR has a high prediction *** study can help formulate relevant preventive and treatment measures.

关键词： Diabetic retinopathy Retinopathy Neovascular Glaucoma Risk factors Nomogram

Intensive care unit-acquired weakness and mechanical ventilation:A reciprocal relationship

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第18期12卷 3644-3647页

作者： Ranjeet Kumar Sinha Sony Sinha Prateek Nishant Arvind Kumar Morya Department of Community Medicine Patna Medical CollegeBiharPatna 800004India Department of Ophthalmology-Vitreo-retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesBiharPatna 801507India Department of Ophthalmology ESIC Medical CollegeBiharPatna 801113India Department of Ophthalmology All India Institute of Medical SciencesTelanganaHyderabad 508126India

Intensive care unit-acquired weakness(ICU-AW;ICD-10 Code:G72.81)is a syndrome of generalized weakness described as clinically detectable weakness in critically ill patients with no other credible *** risk factors for ICU-AW include hyperglycemia,parenteral nutrition,vasoactive drugs,neuromuscular blocking agents,corticosteroids,sedatives,some antibiotics,immobilization,the disease severity,septicemia and systemic inflammatory response syndrome,multiorgan failure,prolonged mechanical ventilation(MV),high lactate levels,older age,female sex,and pre-existing systemic *** is a definite association between the duration of ICU stay and MV with ***,the interpretation that these are modifiable risk factors influencing ICU-AW,appears to be flawed,because the relationship between longer ICU stays and MV with ICU-AW is reciprocal and cannot yield clinically meaningful strategies for the prevention of *** strategies must be based on other risk *** multicentric randomized controlled trials as well as meta-analysis of such studies can be a more useful approach towards determining the influence of these risk factors on the occurrence of ICU-AW in different populations.

关键词： Critical illness Meta-analysis Morbidity Myopathy Polyneuropathy Risk factors

Novel automated non-invasive detection of ocular surface squamous neoplasia using artificial intelligence

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Methodology 2024年第2期14卷 51-64页

作者： Sony Sinha Prasanna Venkatesh Ramesh Prateek Nishant Arvind Kumar Morya Ripunjay Prasad Department of Ophthalmology–Vitreo retina Neuro Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatna 801507India Department of Glaucoma and Research Mahathma Eye Hospital Private LimitedTrichy 620017India Department of Ophthalmology ESIC Medical CollegePatna 801113India Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126India Department of Ophthalmology RP Eye InstituteDelhi 110001India

Ocular surface squamous neoplasia(OSSN)is a common eye surface tumour,characterized by the growth of abnormal cells on the ocular *** includes invasive squamous cell carcinoma(SCC),in which tumour cells penetrate the basement membrane and infiltrate the stroma,as well as non-invasive conjunctival intraepithelial neoplasia,dysplasia,and SCC in-situ thereby presenting a challenge in early detection and *** identification and precise demarcation of the OSSN border leads to straightforward and curative treatments,such as topical medicines,whereas advanced invasive lesions may need orbital exenteration,which carries a risk of *** intelligence(AI)has emerged as a promising tool in the field of eye care and holds potential for its application in OSSN *** algorithms trained on large datasets can analyze ocular surface images to identify suspicious lesions associated with OSSN,aiding ophthalmologists in early detection and *** can also track and monitor lesion progression over time,providing objective measurements to guide treatment ***,AI can assist in treatment planning by offering personalized recommendations based on patient data and predicting the treatment *** manuscript highlights the role of AI in OSSN,specifically focusing on its contributions in early detection and diagnosis,assessment of lesion progression,treatment planning,telemedicine and remote monitoring,and research and data analysis.

关键词： Conjunctival neoplasm Early detection of cancer Machine learning Deep neural network Precision medicine

Management of subretinal hemorrhage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Eye Science 2017年第1期32卷 22-24页

作者： Gregg T.Kokame Department of Surgery University of Hawaii John A Burns School of MedicineHonoluluHI 96813USA Hawaii Macula and retina Institute Hawan 96701USA retina consultants of hawau HonoluluHI 96813USA

Subretinal hemorrhage is a vision threatening complication of exudative age related macular degeneration(AMD) and polypoidal choroidal vasculopathy(PCV). Timely removal or displacement of subretinal hemorrhage from the central macula, ideally within 7 to 10 days after onset, is critical to allowing potential recovery of vision. Surgical techniques with the use of a bubble to displace the subretinal hemorrhage can now be performed with tissue plasminogen activator to lyze the blood and with or without vitrectomy.

关键词： Subretinal hemorrhage age related macular degeneration(AMD) polypoidal choroidal vasculopathy(PCV) vitrectomy tissue plasminogen activator intraocular gas bubble