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World Journal of Clinical Cases 2022年第29期10卷 10600-10605页

作者： Victor Villasuso-Alcocer Juan P Flores-Tapia Fernando Perez-Garfias Andrea Rochel-Perez Nina Mendez-Dominguez Scholar at Direccion General de Calidad y Educacion en Salud Secretaría de SaludMexico 11570Mexico Urology department Hospital Regional de Alta Especialidad de la Peninsula de YucatanMerida 97300YucatanMexico Research and Learning Hospital Regional de Alta Especialidad de la Peninsula de YucatanMerida 97130YucatanMexico

BACKGROUND Diagnosis of emphysematous pyelonephritis has been described around the world for some decades,frequently associated with Escherichia coli and other anaerobic,gas-forming bacteria and mostly in patients living with *** present a case report of emphysematous pyelonephritis in a non-diabetic patient caused by Serratia fonticola as well as a brief literature review to draw attention to this rare pathogen as a cause of *** SUMMARY A 38-year-old female presented with fever,severe pain in the right flank and changes in urinary *** was admitted,and emphysematous pyelonephritis was confirmed by an abdominal computerized tomography and urine cultures;the latter showed Serratia fonticola as a single *** 3 d of being treated with piperacillin/tazobactam and percutaneous drainage she became afebrile,and the gas presence *** Emphysematous pyelonephritis infections in non-diabetic patients are rare but can be severe and *** case suggests that Serratia fonticola infection can occur in patients undergoing invasive or instrumented procedures.

关键词： Serratia fonticola Emphysematous pyelonephritis Urinary tract infections Nephrolithiasis Case report

Digital Intubation without Stylet: Myth or Reality? Case Report

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Open Journal of Anesthesiology 2021年第5期11卷 156-163页

作者： Maya Christiam Mauricio Jesús Alberto Melendez Ordoñez Ismael Bernardo Viveros Peralta Villanueva Verónica Juan José Dosta Herrera Andrea Carolina Jimenez Palacios Jimmy Andersson delgado Criollo Monserrat Escalante Rodríguez Dalia Fernanda Farrera Rámirez Maribel Méndez Suarez Pedro Sánchez Mata residente de anestesiología Hospital Juárez de México Ciudad de México México Médico adjunto al Servicio de anestesiología Unidad Médica de Alta Especialidad (UMAE) Hospital General Doctor Gaudencio Jefe del Servicio de anestesiología Unidad Médica de Alta Especialidad (UMAE) Hospital General Doctor Gaudencio González Garza (LA RAZA) Ciudad de México México

Digital intubation was discovered as one of the first methods to face a difficult airway without direct laryngoscopy. From the very beginning, this technique has been surrounded by much controversy, mainly because it required to be performed by an expert. Nowadays, it remains a useful technique when treating patients with difficult airways, so it is of utmost importance all personnel involved with airway management must know and perfect this technique when scenarios where conventional laryngoscopy or rescue devices for difficult airway are not available or contraindicated. The present work’s main objective is to suggest digital intubation as a safe and effective technique for the management of patients with difficult airways when there are no other devices available. The authors present a successful case of digital intubation on a patient with a difficult airway, demonstrating this technique is useful when performed by expert practitioners and when there is no other equipment available.

关键词： Intubation Intratracheal Oxygenation Anesthesia Airway Management

A Case Report of Hypothyroidism and Pericardial Effusion

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Case Reports in Clinical Medicine 2020年第12期9卷 408-420页

作者： Cacelín Garza José Ramón Cacelín Miranda Rafael Sebastián Cacelín Miranda Ariadna Rosalba Meléndez Ordo&ntilde ez Jesús Alberto Servicio de Medicina Interna Hospital General de Nativitas Tlax Mexico departamento de Medicina Interna Unidad de Cuidados Intensivos Hospital General de Zona No. 1 Instituto Mexicano del Seguro Social Tlax Mexico Facultad de Medicina Universidad Popular Autónoma del Estado de Puebla Puebla México residente de la especialidad de anestesiología Hospital Juárez de México Ciudad de México México

The pericardial sac is made of two layers: the visceral and parietal pericardium. Located between these two layers, the pericardial cavity is found. It contains around 15 to 50 mL of a liquid secreted by mesothelial cells. Pericardial effusion is described as the accumulation of liquid within the pericardial cavity, exceeding the previous mentioned quantity. It has multiple causes, such as malignancy, infectious origins, inflammation, and others, such as hypothyroidism. One of the multiple clinical manifestations associated with hypothyroidism is pericardial effusion. It is related to the severity and duration of the disease, being more frequent in congenital hypothyroidism or cases of a long history of hypothyroidism, as well as clinical hypothyroidism. It can present a clinical challenge mainly due to the discordance between the total volume of the effusion and the clinical symptoms shown by the patient. The main objective of this work is to present a case of a forty-two-year-old male with hypothyroidism-associated pericardial effusion which resolved satisfactorily with hormone replacement therapy.

关键词： Hypothyroidism Pericardial Effusion Echocardiogram Levothyroxin

Acceptance of living liver donation among medical students: A multicenter stratified study from Spain

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World Journal of Gastroenterology 2016年第25期22卷 5800-5813页

作者： Antonio Ríos Ana Isabel López-Navas Ana Isabel López-López Francisco Javier Gómez Jorge Iriarte Rafael Herruzo Gerardo Blanco Francisco Javier Llorca Angel Asunsolo Pilar Sánchez-Gallegos Pedro Ramón Gutiérrez Ana Fernández María Teresa de Jesús laura Martínez-Alarcón Alberto lana Lorena Fuentes Juan Ramón Hernández Julio Virseda José Yelamos José Antonio Bondía Antonio Miguel Hernández Marco Antonio Ayala Pablo Ramírez Pascual Parrilla International Collaborative Donor Project ('Proyecto Colaborativo Internacional Donante' 30007 Casillas Murcia Spain department of Surgery Paediatrics Obstetrics and Gynaecology University of Murcia Avenida de las Fuerzas Armadas 30800 Espinardo Murcia Spain Transplant Unit Surgery Service IMIB - Virgen de la Arrixaca University Hospital Carretera Madrid-Cartagena s/n 30120 El Palmar Murcia Spain Regional Transplant Centre Consejeria de Sanidad y Consumo de la Region de Murcia 30008 Ronda de Levante Murcia Spain Hospital Clinico Universitario Virgen de la Arrixaca Departamento de Cirugia General y del Aparato Digestivo Unidad de Trasplantes 30007 Casillas Murcia Spain department of Psychology Universidad Catolica San Antonio (UCAM) Avenida de los Jeronimos 30107 Guadalupe Murcia Spain department of Urology San Juan University Hospital of Alicante 03010 Calle Pintor Baeza Alicante Spain Universidad de Granada Avenida del Hospicio s/n 18010 Granada Spain Universidad de Navarra Campus Universitario 31080 Pamplona Navarra Spain Universidad Autonoma de Madrid Ciudad Universitaria de cantoblanco 28049 Madrid Spain Servicio de Cirugia HBP y Trasplante Hepatico Complejo Hospitalario Universitario de Badajoz Hospital Infanta Cristina Avenida Elvas s/n 06006 Badajoz Spain Universidad de Cantabria Avenida los Castros s/n 39005 Santander Cantabria Spain departamento de Cirugia Ciencias Medicas y Sociales Facultad de Medicina y Ciencias de la Salud Universidad de Alcala Campus Cientifico-Tecnologico Plaza de San Diego s/n 28801 Alcala de Henares Madrid Spain Facultad de Medicina Universidad de Malaga 29071 Avenida de Cervantes Malaga Spain Servicio de Urologia (Complejo Hospitalario Universitario de Canarias CHUC) y Departamento de Cirugia (Universidad de La Laguna ULL) Calle Molinos de Agua s/n 38207 San Cristobal de La Laguna Santa Cruz de Tenerife Spain departamento de Ciencias Biomedicas Basicas Facultad de Ciencias Biomedicas Universidad Europea de

AIM: To analyze the attitude of Spanish medical students toward living liver donation (LLD) and to establish which factors have an influence on this ***: Study type: A sociological, interdisciplinary, multicenter and observational study. Study population: Medical students enrolled in Spain (n = 34000) in the university academic year 2010-2011. Sample size: A sample of 9598 students stratified by geographical area and academic year. Instrument used to measure attitude: A validated questionnaire (PCID-DVH RIOS) was self-administered and completed anonymously. Data collection procedure: Randomly selected medical schools. The questionnaire was applied to each academic year at compulsory sessions. Statistical analysis: Student´s t test, χ2 test and logistic regression ***: The completion rate was 95.7% (n = 9275). 89% (n = 8258) were in favor of related LLD, and 32% (n = 2937) supported unrelated LLD. The following variables were associated with having a more favorable attitude: (1) age (P = 0.008); (2) sex (P demic year (P lant oneself in the future (P de toward deceased donation (P de toward living kidney donation (P ded (P lation of the body after donation (P dents have a favorable attitude toward LLD.

关键词： Attitude Living liver donation Medical students Transplantation Organ donation Psychosocial variables Spain

Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones

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Asian Journal of Urology 2021年第3期8卷 275-279页

作者： Braulio Omar Manzo Jose David Cabrera Esteban Emiliani Hector Manuel Sanchez Brian Howard Eisner Jose Ernesto Torres Urology department Hospital Regional de Alta Especialidad del BajioBlvd.Milenio#130Col.San Carlos la RonchaLeonGuanajuatoMexico Urology department Fundacion PuigvertUniversidad Autonoma de BarcelonaBarcelonaSpain Urology department Massachusetts General HospitalHarvard Medical SchoolBostonUSA

Objective:To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney ***:A retrospective,longitudinal,descriptive,and observational study was carried out by reviewing the hospital electronic medical record from 2014 to *** adherence to drug treatment was measured 6 months after its initiation,and the numerical values of the metabolic studies were *** tests were performed to compare the difference before and after ***:Ninety patients were evaluated,with 73.3% of *** 180-day overall adherence rate was 61.2% in patients treated with a single drug and 85.4% in patients treated with multiple *** is a statistically significant increase in citrate levels in patients with good adherence in comparison with non-adherent patients(p=0.031 vs.p=0.528).Conclusions:Medical treatment and dietary measures in patients with kidney stones have an initial impact at 6 months on the values of the main urinary metabolic alterations that predispose to calculi formation;the most significant is seen in those patients with adherence to medical treatment for hypocitraturia.

关键词： Kidney stones Renal stones Metabolic disorders Medical treatment Citrate Oxalate Lithiasis

Importance of Pharmacotherapeutic Follow-Up in Odontopediatrics

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Open Journal of Stomatology 2021年第1期11卷 1-13页

作者： Cristina Janeth Montañez-Sosa César Gaitán-Fonseca María Argelia López-Luna Carlos Bermúdez-Jiménez Jesús Luego-Ferreira Silverio Frausto-Esparza Luis Alejandro Aguilera-Galavíz especialidad de Odontopediatría (CLIO) de la Unidad Académica de Odontología Universidad Autónoma de Zacatecas (UAO/UAZ) Zacatecas Mexico Unidad Académica de Ciencias Químicas-QFB Universidad Autónoma de Zacatecas Zacatecas Mexico

The most common cause of admission to the Pediatric dentistry service is dental pain, active deafness and an oppressive sensation that is sometimes throbbing and burning. Pharmacotherapy in Pediatric Dentistry must be effective, safe, and rational in neonates, infants, and children. The pharmacotherapeutic follow-up of pediatric patients from Integral Clinic of the Odontopediatric Specialty (CLIO) and Kindergarten Clinic (CLIJANI), Autonomous University of Zacatecas (UAZ) was carried out. Through an observational, exploratory, and cross-sectional study, 23 patients from the Pediatric Dentistry Specialty Clinic (CLIO/UAO/UAZ) and 35 clinical records of patients from CLIJANI, from August 2019-2020, were analyzed. Prior authorization for the patient, an interview, and pharmacotherapeutic follow-up were performed, recording data on the indicated drug, the dose, and the schedule of use. On carrying out the interview on pharmacotherapy with the parents or guardians who accompany the patient, 91.3% of the pediatric patients were not administered pharmacological treatment. It was observed that there is no adequate adherence to the pharmacological treatment in pediatric patients.

关键词： Tooth Pain Analgesics Antimicrobial Therapy

Brain-derived neurotrophic factor plasma levels and premature cognitive impairment/dementia in type 2 diabetes

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World Journal of Diabetes 2016年第20期7卷 615-620页

作者： Blanca Murillo Ortíz Joel Ramírez Emiliano Edna Ramos-Rodríguez Sandra Martínez-Garza Hilda Macías-Cervantes Sergio Solorio-Meza Texar Alfonso Pereyra-Nobara Unidad de Investigación en Epidemiología Clínica Unidad Médica de Alta Especialidad No. 1 BajioInstituto Mexicano del Seguro Social departamento de Ciencias Médicas División Ciencias de la SaludUniversidad de Guanajuato

AIM To assess the relationship of brain-derived neurotrophic factor(BDNF) with cognitive impairment in patients with type 2 diabetes. METHODS The study included 40 patients with diabetes mellitus type 2(DM2), 37 patients with chronic kidney disease in hem dialysis hemodialysis therapy(HD) and 40 healthy subjects. BDNF in serum was quantified by ELISA. The Folstein Mini-Mental State Examination was used to evaluate cognitive *** The patients with DM2 and the patients in HD were categorized into two groups, with cognitive impairment and without cognitive impairment. The levels of BDNF showed significant differences between patients with DM2(43.78 ± 9.05 vs 31.55 ± 10.24, P = 0.005). There were no differences between patients in HD(11.39 ± 8.87 vs 11.11 ± 10.64 P = 0.77); interestingly, ferritin levels were higher in patients with cognitive impairment(1564 ± 1335 vs 664 ± 484 P = 0.001). The comparison of BDNF values, using a Kruskal Wallis test, between patients with DM2, in HD and healthy controls showed statistical differences(P decrease of BDNF occurs early and progressively in patients in HD.

关键词： Diabetes mellitus type 2 Hemodialysis Brain-derived neurotrophic factor Folstein mini-mental Premature cognitive impairment

Anterior and Posterior Approach Results for Treatment of Cervical Myelopathy in the Elderly: A 10-Year Experience in a Mexican Institution

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Open Journal of Orthopedics 2021年第7期11卷 207-219页

作者： Mauricio Daniel Sánchez-Calderón María Elena Córdoba-Mosqueda José Ramón Aguilar-Calderón Carlos René Domínguez-Herz Diego Ochoa-Cacique Daniel Alejandro Vega-Moreno Victor Andrés Reyes-Rodriguez Ulises García-González Abraham Ibarra-de la Torre Rodrigo Efraín Hernández-Reséndiz department of Neurosurgery Hospital Central Sur de Alta Especialidad de Alta Especialidad de PEMEX Periferico sur 4091 Fuentes del Pedregal Tlalpan México City México department of Neurosurgery Hospital Regional de Alta Especialidad “Centenario de la Revolución Mexicana” ISSSTE Cuernavaca Palo Escrito Emiliano Zapata department of Neurosurgery Hospital Central Norte PEMEX Mexico City México department of Neurosurgery Hospital &Aacute ngeles Clí nica Londres Mexico City Mexico

Introduction: degeneration of the cervical spine (CDSD) prevalence is nearly 90% by the 7th decade. This is the first research that compares the outcomes between the Anterior Approach (AA) and Posterior Approach (PA) ... 详细信息

Introduction: Degeneration of the cervical spine (CDSD) prevalence is nearly 90% by the 7th decade. This is the first research that compares the outcomes between the Anterior Approach (AA) and Posterior Approach (PA) to cervical myelopathy (CM) in the elderly. Materials and Methods: A retrospective observational study of electronic health records at the Hospital Central Sur de Alta Especialidad (HCSAE), PEMEX from January 2010 to May 2020 with patients older than 60 years submitted to cervical surgery. For the analysis we elaborated two groups according to the surgical approach: AA vs PA;we analyzed the trans-operative behavior, the immediate outcome, and after 3 months, 6 months, and 1 year. Results: As a total of 145 patients, the prevalence of CM in elderly was the 63.8% with a median age of 69 (64 - 75) years. We found statistical differences in strength outcome only in the P3m (p = 0.011), for sensitivity we found major prevalence of affection in the PA group. We didn’t report a significant difference in the Neck Disability Index (NDI) at all measures, but the PA presented a major incapacity. The Nurick scale results were significant in all stages (p . Discussion: Patients show significant improvements in outcome measures with either anterior or posterior surgery. Both approaches are highly efficacious in preventing neurolo

关键词： Cervical Spine Surgical Approach Elderly Cervical Myelopathy Cervical degenerative Spine Disease

Acetylsalicylic Acid Administered in Patients with Type 2 Diabetes Mellitus and Its Effect on the Antioxidant Enzyme System

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Journal of Diabetes Mellitus 2022年第4期12卷 252-262页

作者： Sara Pascoe-González Karina Celia Morgado-Castillo Maria Guadalupe Ramos-Zavala Ernesto Germán Cardona-Muñoz Fernando Grover-Paez María Claudia Espinel-Bermúdez Sandra Ofelia Hernández-González Instituto de Terapéutica Experimental y Clínica (INTEC) Departamento de Fisiología Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara México Unidad de Investigación Biomédica 02 Unidad Médica de Alta Especialidad Hospital de Especialidades Centro Médico Nacional de Occidente del Instituto Mexicano del Seguro Social Guadalajara México

Type 2 diabetes mellitus and its complications are associated with oxidative stress and the depletion of antioxidant defenses. The influence of acetylsalicylic acid on reversing the decrease in antioxidants, insulin resistance, glucose homeostasis, and inflammatory cascade can help prevent diabetes complications. Purpose: The aim of the study was to evaluate the effect of acetylsalicylic acid on the antioxidant enzymatic system in patients with diabetes. Methods: A randomized, double-blind, placebo-controlled clinical trial was carried out in 21 patients of both sexes with Type 2 diabetes for less than five years at the time of diagnosis, without pharmacological treatment, and randomly selected. Acetylsalicylic acid (300 mg) was administered orally for three months to the study group (n = 11) compared to the placebo control group (n = 10). Before and after the intervention, anthropometric and metabolic measurements were taken, fasting plasma glucose, glycated hemoglobin A1c, lipid profile panel, glutathione peroxidase, superoxide dismutase, catalase, and antioxidant capacity/activity were determined;values are presented as mean ± standard deviation. Intra- and intergroup differences were tested by Wilcoxon signed rank and Mann-Whitney U test, respectively;p-value ≤ 0.05 was considered statistically significant. Results: The acetylsalicylic acid group showed a decrease in weight (85.6 ± 19.3 vs. 84.1 ± 19.0 kg p = 0.01), cholesterol (205.9 ± 16.6 vs. 186.0 ± 23.2 mg/dL p = 0.02), and glycated hemoglobin A1c (7.8% ± 0.9% vs. 7.0% ± 0.7% p = 0.02). The placebo group exhibited reduction in weight (76.1 ± 14.9 vs. 74.9 ± 15.0 kg p = 0.04), glycated hemoglobin A1c (6.9% ± 0.6% vs. 6.2% ± 0.4% p = 0.004), and total antioxidant capacity (4.1 ± 0.5 vs. 4.8 ± 0.3 mmol/L p = 0.002). Conclusion: The administration of acetylsalicylic acid did not modify the antioxidant enzyme system.

关键词： Type 2 Diabetes Mellitus Acetylsalicylic Acid Oxidative Stress Glucose Glycated Hemoglobin A1c

Diabetic Patients develop Greater Intensity of Postoperative Pain than Non-Diabetics after Open Cholecystectomy: A Pilot Study

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Journal of Biosciences and Medicines 2021年第6期9卷 67-75页

作者： Rocío Adriana Martínez-Alpuche Erick Mauricio Brindis-Fuentes Crystel Guadalupe Guzmán-Priego Francisco Valenzuela-Priego Leonor Ivonne Parra-Flores Jorge Elías Torres-López Pain Mechanisms laboratory División Académica de Ciencias de la Salud Universidad Juárez Autónoma de Tabasco Villahermosa Tabasco México department of Anaesthesiology Hospital Regional de Alta Especialidad “Dr. Juan Graham Casasús” Villahermosa Tabasco México

Background: Pre-clinical and clinical studies have shown that inflammatory pain intensity is increased under diabetes condition. Open cholecystectomy (OC) is a surgical procedure with predictable postoperative pain. However, the comparison of postoperative pain due to open cholecystectomy in diabetic and non-diabetic patients remains unknown. The research question to answer was whether diabetic patients undergoing OC development greater intensity of postoperative pain than non-diabetic patients. Methods: The study was conducted between June 2016 and February 2018 at the Regional Hospital of High Specialty “Dr. Juan Graham Casasús” of Villahermosa, Tabasco, Mexico. Seventy patients in two groups of 35 patients each scheduled for OC under general anesthesia were studied. Pain was assessed using the 11-point numerical rating scale (NRS). The primary endpoint was to know NRS pain scores after awaking of general anesthesia. Secondary outcomes included the time of onset of pain and comparing NRS scores between diabetic and non-diabetic patients undergoing OC. Results: Diabetic patients reported significantly greater intensity pain than non-diabetic patients. The mean overall pain score in the diabetic and non-diabetic patients was 7.2 ± 0.3 and 5.3 ± 0.3 (P = 0.0002), respectively. Furthermore, 60% of diabetic patients had severe pain (NRS ≥ 8) compared to 20% of non-diabetics (P = 0.006). The time to onset postoperative pain was about 35 minutes in both groups (P = 0.876). Conclusions: Diabetic patients undergoing OC have greater intensity postoperative pain and also more frequency of patients with severe pain scores compared with non-diabetic patients. Therefore, analgesic treatment in those patients should consider this point in order to provide a satisfactory postoperative analgesia.

关键词： Postoperative Pain Inflammatory Pain Cholecystectomy Diabetes Observational Study