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Mapping the territories of the mountain-foothill zone of Tajikistan exposed to mudflows

Journal of Mountain Science 2025年第1期22卷 16-30页

作者： SAFAROV Mustafo KANG Shichang FAZYLOV Ali GULAYOZOV Majid NAVRUZSHOEV Hofiz BANERJEE Abhishek MAMADJANOV Yunus Key Laboratory of Cryospheric Science and Frozen Soil Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China research center for Ecology and Environment of Central Asia(Dushanbe) Dushanbe 734063Tajikistan University of Chinese Academy of sciences Beijing 100049China Institute of Water Problems Hydropower and Ecology of the National Academy of Sciences of TajikistanDushanbe 734042Tajikistan Mountain Societies research Institute University of Central AsiaDushanbe 734000Tajikistan State Scientific Institution“center for research of Glaciers of the National Academy of sciences of Tajikistan” Dushanbe 734025Tajikistan

In recent years,mudflows have emerged as a significant threat to infrastructure and lives,exhibiting increased frequency and *** study collectively addresses the rising threat of natural hazards,specifically mudflows in mountain-foothill zones in Tajikistan,utilizing UAV and remote sensing technologies to monitor their *** 2020 to 2023,we employed a QC-2 Micro UAV and a DJI Phantom 4 quadcopter to capture high-resolution aerial imagery across multiple affected districts,supplemented by pre-and post-event Sentinel-2 images analyzed using the Normalized Difference Water Index(NDWI)and Normalized Difference Vegetation Index(NDVI).Our analysis revealed that 49 districts and cities experienced significant mudflow events,resulting in estimated damages and economic losses of 30.2 million USD,with particularly severe impacts noted in the Khuroson,Tojikobod,Vakhsh,Panjakent,Lakhsh,and *** composition of mudflows in the six studied areas predominantly consisted of clay,with some regions featuring mudstone and a few exhibiting a mixture of both *** findings indicate the predominance of rain-induced mudflows in foothill areas,contrasting with rain-snow,glacial,and lake-outburst-induced mudflows in mountainous *** underscores the urgent need for effective disaster risk management strategies in vulnerable *** UAV and remote sensing technologies provides crucial information for analyzing damages,identifying vulnerable areas,and advising emergency response efforts,thereby enhancing disaster risk management in Tajikistan.

关键词： Disaster Mudflows Remote sensing Unmanned aerial vehicles Tajikistan

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Efficient remediation of different concentrations of Cr-contaminated soils by nano zero-valent iron modified with carboxymethyl cellulose and biochar

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Journal of Environmental sciences 2025年第1期147卷 474-486页

作者： Lihong Xie Qiyan Ma Qingjun Chen Yiyang Liu Pengfei Guo Jinlan Zhang Guilan Duan Aijun Lin Tingting Zhang Shangyi Li Department of Environmental Science and Engineering College of Chemical EngineeringBeijing University of Chemical TechnologyBeijing 100029China China National Petroleum and Chemical Planning Institute Beijing 100013China State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China

Nano zero-valent iron(nZVI)is widely used in soil remediation due to its high ***,the easy agglomeration,poor antioxidant ability and passivation layer of Fe-Cr coprecipitates of nZVI have limited its application scale in Cr-contaminated soil remediation,especially in high concentration of Cr-contaminated ***,we found that the carboxymethyl cellulose on nZVI particles could increase the zeta potential value of soil and change the phase of *** with the presence of biochar,97.0%and 96.6%Cr immobilization efficiency through CMC-nZVI/BC were respectively achieved in high and low concentrations of Cr-contaminated soils after 90-days *** addition,the immobilization efficiency of Cr(VI)only decreased by 5.1%through CMC-nZVI/BC treatment after 10 weeks aging in air,attributing to the strong antioxidation *** for the surrounding Crcontaminated groundwater,the Cr(VI)removal capacity of CMC-nZVI/BC was evaluated under different reaction conditions through column experiments and COMSOL ***-nZVI/BC could efficiently remove 85%of Cr(VI)in about 400 hr when the initial Cr(VI)concentration was 40 mg/L and the flow rate was 0.5 mL/*** study demonstrates that uniformly dispersed CMC-nZVI/BC has an excellent remediation effect on different concentrations of Cr-contaminated soils.

关键词： Carboxymethyl cellulose Nanoscale zero-valent iron Biochar Cr-contaminated soils

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High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasis

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Animal Models and Experimental Medicine 2025年第1期8卷 162-170页

作者： Yitong Li Tingting Feng Qinghong Wang Yue Wu Jue Wang Wenlong Zhang Qi Kong NHC Key Laboratory of Human Disease Comparative Medicine Beijing Engineering Research Center for Experimental Animal Models of Human Critical DiseasesInstitute of Laboratory Animal SciencesChinese Academy of Medical Sciences(CAMS)and Comparative Medicine CenterPeking Union Medical College(PUMC)BeijingChina

Background:Breast cancer is the most common cancer in women,and in advanced stages,it often metastasizes to the ***,research on the biological mechanisms of breast cancer brain metastasis and potential therapeutic targets are ***:Differential gene expression analysis(DEGs)for the datasets GSE43837 and GSE125989 from the GEO database was performed using online analysis tools such as GEO2R and *** investigation related to SULF1 was conducted using online databases such as Kaplan-Meier Plotter and ***,expression levels,variations,associations with HER2,biological processes,and pathways involv-ing SULF1 could be analyzed using UALCAN,cBioPortal,GEPIA2,and LinkedOmics ***,the sensitivity of SULF1 to existing drugs was explored using drug databases such as RNAactDrug and ***:High expression of SULF1 was associated with poor prognosis in advanced breast cancer brain metastasis and was positively correlated with the expression of *** the metastatic breast cancer population,SULF1 ranked top among the 16 DEGs with the highest mutation rate,reaching 11%,primarily due to *** and GSEA analyses revealed that the genes co-expressed with SULF1 were positively enriched in the‘ECM-receptor interaction’gene set and negatively enriched in the‘Ribosome’gene ***,docetaxel and vinorelbine can act as treatment options if the expression of SULF1 is ***:This study,through bioinformatics analysis,unveiled SULF1 as a poten-tial target for treating breast cancer brain metastasis(BM).

关键词： brain metastasis breast cancer potential therapeutic target SULF1

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First documentation of early Silurian conodonts from western Thailand and its geological implications

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Journal of Palaeogeography 2025年第1期14卷 157-171页

作者： Zhong-Yang Chen Hathaithip Thassanapak Wen-Jie Li Xue-Jin Wu Mongkol Udchachon Xiang Fang Clive Burrett State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of Sciences University of Chinese Academy of sciences Excellence center in Evolution of Life Basin Studies and Applied Palaeontology Palaeontological Research and Education Center Mahasarakham University Department of Biology Faculty of Science Mahasarakham University

The early Silurian conodonts are firstly described and illustrated from western Thailand. Samples were collected from the Kroeng Kravia Forest Park area for conodont and lithofacies analyses. An upper Telychian Lower Pterospathodus amorphognathoides amorphognathoides Subzone is recognized for the studied succession. Three lithofacies were identified from the carbonate succession, including stromatolite-thrombolite limestone, nodular limestone, and red limestone. Both analyses on lithofacies and conodont assemblages indicate a deeper marine depositional environment. The conodont fauna in the study area is similar to that from Baoshan of Yunnan Province and Langao of Shaanxi Province in West China and resembles that from similar depositional environments in Australia, Laurentia, and peri-Gondwana, suggesting good connections among these regions by ocean currents.

关键词： Silurian Conodonts Deep marine environment Western Thailand Sibumasu

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DTD1 modulates synaptic efficacy by maintaining D-serine and D-aspartate homeostasis

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Science China(Life sciences) 2025年第2期68卷 467-483页

作者： Xiao Liu Chaojuan Yang Zhuoran Lin Jianing Li Bin Yin Xuepei Lei Wei Han Boqin Qiang Pengcheng Shu Chen Zhang Xiaozhong Peng State KeyLaboratoryofCommon Mechanism research for Major Diseases Departmentof Biochemistry&Molecular BiologyMedicalPrimate Research CenterNeuroscienceCenterInstituteof Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijing 100005China State Key Laboratory of Respiratory Health and Multimorbidity Beijing 100005China Institute of Laboratory Animal sciences Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China School of Basic Medical sciences Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijing 100069China Key Laboratoryof Biomechanics and Mechanobiology(Beihang University) Ministryof EducationBeijing AdvancedInnovation Center for Biomedical EngineeringSchoolof Engineering MedicineBeihang UniversityBeijing 100191China Chinese Institute for Brain research Beijing 102206China

D-serine and D-aspartate are involved in N-methyl-D-aspartate receptor(NMDAR)-related physiological and pathological ***-t RNA deacylase 1(DTD1)may biochemically contribute to D-serine or D-aspartate ***,it is unclear thus far whether DTD1 regulates D-serine or D-aspartate content in neurobiological *** the present research,we found that DTD1 was essential to maintain the D-serine or D-aspartate homeostasis,which was consistent with the phenomenon that DTD1-deficiency resulted in changes in the quantity changes of functional NMDAR subunits in postsynaptic ***,DTD1 played a considerable role in regulating dendritic morphology and synaptic *** a consequence,DTD1 affected neurobiological events,including the synaptic strength of the CA3-to-CA1 circuit,dendritic spine density of hippocampal pyramidal neurons,and behavioral performance of mice in the Morris water *** findings highlight the important role of DTD1 in synaptic transmission,neuronal morphology,and spatial learning and memory and suggest an undisclosed mechanism of DTD1 that participates the regulation of D-serine or D-aspartate homeostasis in hippocampal neurons.

关键词： D-aminoacyl-tRNA deacylase 1 D-serine D-aspartate synaptic transmission neuronal morphology spatial learning and memory

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Selenate-based heterojunction with cobalt-nickel paired site for electrocatalytic oxidation of 5-hydroxymethylfurfural coupling water splitting to produce hydrogen

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Journal of Energy Chemistry 2025年第2期101卷 156-162页

作者： Zhengru Yang Jia Hui Wangxi Fan Pengcheng Liu Chunyong Zhang Shuang Dong Zhou Yang Department of Chemistry and Chemical Engineering & Jiangsu Key Laboratory of Clean Energy Storage and Conversion Jiangsu University of Technology Engineering Technology and Materials research center China Academy of Transportation Sciences School of Chemical Engineering and Materials Changzhou Institute of Technology

It is very appealing that 5-hydroxymethylfurfural（HMF） is electrocatalytical oxidized as 2,5-furandicarboxylic acid（FDCA） linking to non-classical cathodic hydrogen（H2） ***,the electrocatalysts for electrocatalytic HMF oxidative reaction（e-HMFOR） have been facing low Faradaic efficiency（FE） and high water splitting ***,we propose a strategy of the NiSeO3@（CoSeO3）4heterojunction by constructing a Co-Ni paired site,where the Co site is in charge of adsorbing for HMF while the electrons are transferred to the Ni site,thus giving the NiSeO3@（CoSeO3）4heterojunction superior electrocata lytic performances for e-HMFOR and water *** optimizing conditions,the NiSeO3@（CoSeO3）4heterojunction has high conversion of 99.7%,high selectivity of 99.9%,and high FE of 98.4% at 1.3 V,as well as low cell voltage of 1.31 V at 10 mA cm-2in 1 M KOH+0.1 M *** study offers a potential insight for e-HMFOR to high value-added FDCA coupling water splitting to produce H2in an economical manner.

关键词： Co-Ni paired site e-HMFOR FDCA Heterojunction Hydrogen evolution

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Impact of residual antibiotics on microbial decomposition of livestock manures in Eutric Regosol:Implications for sustainable nutrient recycling and soil carbon sequestration

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Journal of Environmental sciences 2025年第1期147卷 498-511页

作者： Linfa Fang Prakash Lakshmanan Xiaoxuan Su Yujia Shi Zheng Chen Yu Zhang Wei Sun Junxi Wu Ran Xiao Xinping Chen Interdisciplinary research center for Agriculture Green Development in Yangtze River Basin College of Resources and EnvironmentSouthwest UniversityChongqing 400715China Key Laboratory of Sugarcane Biotechnology and Genetic Improvement(Guangxi) Ministry of Agriculture and Rural AffairsGuangxi Key Laboratory of Sugarcane Genetic ImprovementSugarcane Research InstituteGuangxi Academy of Agricultural SciencesNanning 530007China Queensland Alliance for Agriculture and Food Innovation University of QueenslandSt Lucia 4067QLDAustralia Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and National Resources ResearchChinese Academy of SciencesBeijing 100101China

The land application of livestock manure has been widely acknowledged as a beneficial approach for nutrient recycling and environmental ***,the impact of residual antibiotics,a common contaminant of manure,on the degradation of organic compounds and nutrient release in Eutric Regosol is not well ***,we studied,how oxytetracycline(OTC)and ciprofloxacin(CIP)affect the decomposition,microbial community structure,extracellular enzyme activities and nutrient release from cattle and pig manure using litterbag incubation *** showed that OTC and CIP greatly inhibited livestock manure decomposition,causing a decreased rate of carbon(28%-87%),nitrogen(15%-44%)and phosphorus(26%-43%)*** relative abundance of gramnegative(G-)bacteria was reduced by 4.0%-13%while fungi increased by 7.0%-71%during a 28-day incubation ***-occurrence network analysis showed that antibiotic exposure disrupted microbial interactions,particularly among G-bacteria,G+bacteria,and *** changes in microbial community structure and function resulted in decreased activity of urease,β-1,4-N-acetyl-glucosaminidase,alkaline protease,chitinase,and catalase,causing reduced decomposition and nutrient release in cattle and pig *** findings advance our understanding of decomposition and nutrient recycling from manure-contaminated antibiotics,which will help facilitate sustainable agricultural production and soil carbon sequestration.

关键词： Residual antibiotics Livestock manure decomposition microbial community Co-occurrence network Enzyme activities

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Phase transition in modified thermodynamics of Kerr-AdS black holes

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Chinese Physics C 2025年第1期49卷 350-358页

作者： Qin Liu Xiaoning Wu Xiao Zhang School of Physical Science and Technology Guangxi UniversityNanning 530004China Guangxi center for Mathematical research Guangxi UniversityNanning 530004China Institute of Mathematics Academy of Mathematics and Systems Science and Hua Loo-Keng LaboratoryChinese Academy of SciencesBeijing 100190China School of Mathematical sciences University of Chinese Academy of SciencesBeijing 100049China

In this study,we investigate the critical phenomena of Kerr-AdS black holes under the modified first law of ***,we considered modified black hole thermodynamics that exhibit a van der Waalslike phase *** critical exponents were calculated,and then,a swallowtail diagram of free energy was *** with existing results,the main difference is the correspondence between the thermal quantities of Kerr-AdS black holes and the van der Waals *** a previous study[***,***,and ***,***.D 85044005(2012)],the correspondence was(Ω_(H),J)→(V,P),while in our study,the correspondence was(J,Ω_(H))→(V,P).This difference was owing to the rotating *** modified black hole thermodynamics were associated with rotating *** free energy in such a reference contains extra rotating energy,which induces a Legendre transformation in the(Ω_(H),J)cross-section,causing the difference in correspondence.

关键词： Kerr-AdS black hole black hole thermodynamics phase transition of black hole

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Degradation of gaseous hydrocarbons in aerated stirred bioreactors inoculated with Rhodococcus erythropolis:Effect of the carbon source and SIFT-MS method development

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Journal of Environmental sciences 2025年第1期147卷 268-281页

作者： Paula Alejandra Lamprea Pineda Kristof Demeestere Allan Augusto Alvarado-Alvarado Frank Devlieghere Nico Boon Herman Van Langenhove Christophe Walgraeve research group EnVOC Department of Green Chemistry and TechnologyFaculty of Bioscience EngineeringGhent UniversityCoupure Links 6539000Ghent Belgium research group FMFP Department of Food TechnologySafety and HealthFaculty of Bioscience EngineeringGhent UniversityCoupure Links 6539000Ghent Belgium center for microbial Ecology and Technology-CMET Department of BiotechnologyFaculty of Bioscience EngineeringGhent UniversityCoupure Links 6539000Ghent Belgium

The study of microbial hydrocarbons removal is of great importance for the development of future bioremediation *** this study,we evaluated the removal of a gaseous mixture containing toluene,m-xylene,ethylbenzene,cyclohexane,butane,pentane,hexane and heptane in aerated stirred bioreactors inoculated with Rhodococcus erythropolis and operated under non-sterile *** the real-time measurement of hydrocarbons,a novel systematic approachwas implemented using Selected-Ion Flow TubeMass Spectrometry(SIFTMS).The effect of the carbon source(~9.5 ppmv)on(i)the bioreactors’performance(BR1:dosed with only cyclohexane as a single hydrocarbon versus BR2:dosed with a mixture of the 8 hydrocarbons)and(ii)the evolution of microbial communities over time were *** results showed that cyclohexane reached a maximum removal efficiency(RE)of 53%±4%in *** BR2,almost complete removal of toluene,m-xylene and ethylbenzene,being the most water-soluble and easy-to-degrade carbon sources,was *** below 32%were obtained for the remaining *** exposing the microbial consortium to only the five most recalcitrant hydrocarbons,REs between 45%±5%and 98%±1%were *** addition,we observed that airborne microorganisms populated the bioreactors and that the type of carbon source influenced the microbial communities *** abundance of species belonging to the genus Rhodococcus was below 10%in all bioreactors at the end of the *** work provides fundamental insights to understand the complex behavior of gaseous hydrocarbon mixtures in bioreactors,along with a systematic approach for the development of SIFT-MS methods.

关键词： Hydrocarbons SIFT-MS Rhodococcus erythropolis Biodegradation Bioreactors

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Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第1期68卷 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-Tong Di Man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines(Chinese Academy of sciences) Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical OncogenomicsPeking University Shenzhen Graduate SchoolShenzhen 518055China Shenzhen Bay Laboratory Shenzhen 518055China University of Chinese Academy of sciences Beijing 100049China State Key Laboratory of microbial Metabolism School of Life Sciences&BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical UniversityGuiyang 550014China Molecular Biology Experimental center Germplasm Bank of Wild Species in Southwest ChinaKunming Institute of BotanyChinese Academy of SciencesKunming 650201China Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical SciencesBeijing 100730China

In the intricate process of natural product biosynthesis,a metabolon can enhance metabolic flux by associating sequential enzymes.A fungal metabolon,comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G,is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide *** notoamide E as a substance,Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation,followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium ***,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol *** provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

关键词： metabolon Diels-Alder reaction semipinacol rearrangement biosynthesis notoamides spiro polycyclic alkaloids

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