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A new model of flow over stretching(shrinking)and porous sheet with its numerical solutions

Applied Mathematics(A Journal of Chinese Universities) 2024年第3期39卷 381-397页

作者： Azhar Ali Dil Nawaz Khan Marwat Saleem Asghar Department of Mathematics Islamia College Peshawar 25120Jamrod roadPeshawarKhyber PakhtunkhwaPakistan Department of Mathematics COMSATS Institute of Information TechnologyPark RoadTarlai KalanIslamabad 45550Pakistan

The viscous fluid flow and heat transfer over a stretching(shrinking)and porous sheets of nonuniform thickness are investigated in this *** modeled problem is presented by utilizing the stretching(shrinking)and porous velocities and variable thickness of the sheet and they are combined in a ***,the new problem reproduces the different available forms of flow motion and heat transfer maintained over a stretching(shrinking)and porous sheet of variable thickness in one *** a result,the governing equations are embedded in several parameters which can be transformed into classical cases of stretched(shrunk)flows over porous sheets.A set of general,unusual and new variables is formed to simplify the governing partial differential equations and boundary *** final equations are compared with the classical models to get the validity of the current simulations and they are exactly matched with each other for different choices of parameters of the current problem when their values are properly adjusted and ***,we have recovered the classical results for special and appropriate values of the parameters(δ_(1),δ_(2),δ_(3),c,and B).The individual and combined effects of all inputs from the boundary are seen on flow and heat transfer properties with the help of a numerical method and the results are compared with classical solutions in special *** is noteworthy that the problem describes and enhances the behavior of all field quantities in view of the governing *** result shows that the dual solutions can be found for different possible values of the shrinking parameter.A stability analysis is accomplished and apprehended in order to establish a criterion for the determinations of linearly stable and physically compatible *** significant features and diversity of the modeled equations are scrutinized by recovering the previous problems of fluid flow and heat transfer from a uniformly heated sheet

关键词： permeable stretching(shrinking)sheets sheet of variable thickness heat transfer numerical(dual)solutions stability analysis

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Multi-Elemental Chemostratigraphy,Sequence Development,Depositional History,and Environmental Importance of Early Eocene Red Beds(Kuldana Formation)in NW Himalayas,Pakistan

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Journal of Earth Science 2024年第2期35卷 349-375页

作者： Amir Shahzad George Kontakiotis Thierry Adatte Khawaja Shoaib Ahmed Muhammad Tayyib Riaz Hammad Tariq Janjuhah Evangelia Besiou institute of Geology University of Azad Jammu and KashmirMuzaffarabad13100Pakistan Department of Historical Geology-Paleontology Faculty of Geology and GeoenvironmentSchool of Earth SciencesNational and Kapodistrian University of AthensPanepistimiopolisZografou15784Greece institute of Earth Sciences(ISTE) University of LausanneLausanneCH-1015Switzerland Department of Geology Shaheed Benazir Bhutto UniversitySheringalPeshawar18050Pakistan

The Eocene Kuldana Formation(KF)in the Yadgar area of Pakistan,comprises a diverse range of sedimentary facies,including variegated red beds of shales,mudstones,and sandstones,as well as interbedded limestone and *** this study,we conducted an integrated micropaleontological,sedimentological,mineralogical,and geochemical investigation to determine the depositional setting,biochronology,provenance,and paleoclimate of the *** study identified six lithofacies and six microfacies,which indicate a variety of environments ranging from floodplains and channels to the margins and shallow marine *** nannofossil biostratigraphy places the KF in the Early Eocene,more precisely the NP10 zone(Ypresian),and the fossil zone of benthic foraminifera classifies the study section as the Shallow Benthic Zone SBZ-8(Middle Ilerdian 2).In terms of petrography,the KF sandstone was classified as litharenite and feldspathic litharenite,while the QtFL diagram suggests a recycled *** proxies indicate an oxidizing environment,a high-to-low regular sedimentation rate,moderate-to-intense chemical weathering in the source region,and a warm-humid to dry climate during the deposition of ***,the findings suggest that the deposition of KF marks the end of Neo-Tethys due to the Early Eocene Indian–Kohistan collision and that the uplifting of the Himalayas provided the source for the deposition of KF in the foreland *** study provides new insights into the depositional environment,biochronology,provenance,and paleoclimate of KF,and highlights the potential for red beds as reliable indicators of oxygenation levels in proximity to mineral deposits.

关键词： sedimentary microfacies Paleocene–Eocene thermal maximum stratigraphic correlations paleoenvironmental reconstruction nannofossils paleontology

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National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan Rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

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Soil erosion susceptibility mapping of Hangu Region,Kohat Plateau of Pakistan using GIS and RS-based models

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Journal of Mountain Science 2024年第8期21卷 2547-2561页

作者： Fakhrul ISLAM Liaqat Ali WASEEM Tehmina BIBI Waqar AHMAD Muhammad SADIQ Matee ULLAH Walid SOUFAN Aqil TARIQ Department of Geology Khushal Khan Khattak UniversityKarak 27200Pakistan Department of Geography Government College University FaisalabadPunjab 38000Pakistan institute of Geology The University of Azad Jammu&KashmirMuzaffarabad 13100Pakistan Department of Earth Sciences Changan UniversityXi’an 710003China NCEG University of PeshawarPeshawar 25120Pakistan Faculty of Earth Sciences Geography and AstronomyUniversity of ViennaVienna 1090Austria Plant Production Department College of Food and Agriculture SciencesKing Saud UniversityRiyadh 11451Saudi Arabia Department of Wildlife Fisheries and AquacultureCollege of Forest ResourcesMississippi State UniversityMS 39762USA

Soil erosion is a crucial geo-environmental hazard worldwide that affects water quality and agriculture,decreases reservoir storage capacity due to sedimentation,and increases the danger of flooding and ***,this study uses geospatial modeling to produce soil erosion susceptibility maps(SESM)for the Hangu region,Khyber Pakhtunkhwa(KPK),*** Hangu region,located in the Kohat Plateau of KPK,Pakistan,is particularly susceptible to soil erosion due to its unique geomorphological and climatic ***,the Hangu region is characterized by a combination of steep slopes,variable rainfall patterns,diverse land use,and distinct soil types,all of which contribute to the complexity and severity of soil erosion *** factors necessitate a detailed and region-specific study to develop effective soil conservation *** this research,we detected and mapped 1013 soil erosion points and prepared 12 predisposing factors(elevation,aspect,slope,Normalized Differentiate Vegetation Index(NDVI),drainage network,curvature,Land Use Land Cover(LULC),rainfall,lithology,contour,soil texture,and road network)of soil erosion using GIS ***,GIS-based statistical models like the weight of evidence(WOE)and frequency ratio(FR)were applied to produce the SESM for the study *** SESM was reclassified into four classes,i.e.,low,medium,high,and very high *** results of WOE for SESM show that 16.39%,33.02%,29.27%,and 21.30%of areas are covered by low,medium,high,and very high zones,*** contrast,the FR results revealed that 16.50%,24.33%,35.55%,and 23.59%of the areas are occupied by low,medium,high,and very high ***,the reliability of applied models was evaluated using the Area Under Curve(AUC)*** validation results utilizing the area under curve showed that the success rate curve(SRC)and predicted rate curve(PRC)for WOE are 82%and 86%,respectively,while SRC and PRC for FR are 85%and 96%,res

关键词： Soil erosion Geospatial technology Statistical models Hangu Pakistan

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De novo mutation of NAXE(APOAIBP)-related early-onset progressive encephalopathy with brain edema and/or leukoencephalopathy-1:A case report

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World Journal of Clinical Cases 2023年第14期11卷 3340-3350页

作者： Le Ding Ting-Ting Huang Guo-Huan Ying Shang-Yu Wang Hai-Feng Xu Hao Qian Faiza Rahman Xiao-Peng Lu Hu Guo Guo Zheng Gang Zhang Department of Neurology Children’s Hospital of Nanjing Medical UniversityNanjing 210008Jiangsu ProvinceChina rehman medical institute peshawar Peshawar 39250Pakistan

BACKGROUND Early-onset progressive encephalopathy with brain edema and/or leukoencephalopathy-1(PEBEL1)is a rare autosomal recessive severe neurometabolic *** aim of this study was to investigate the clinical characteristics and genetic pathogenicity of PEBEL1 caused by rare NAXE(or APOA1BP)-related *** SUMMARY The patient was a girl aged 2 years and 10 *** was hospitalized due to walking disorder for>40 *** clinical manifestations were ataxia,motor function regression,hypotonia,and eyelid *** 1 mo of hospitalization,she developed sigh breathing,respiratory failure,cerebellar edema and brain hernia,and finally she *** were found in cranial imaging,including cerebellar edema accompanied by symmetrical *** whole exome sequencing,we detected NAXE compound heterozygous variation(NM 144772.3)c.733A>C(***245Gln,dbSNP:rs770023429)and novel variation c.370G>T(***124Cys)in the germline *** clinical features and core phenotypes of this case were consistent with 18 previously reported cases of *** This is the first case of NAXE-related PEBEL1 with severe clinical phenotype in China' *** ***124Cys mutation discovered in this case has enriched the pathogenic variation spectrum of NAXE.

关键词： Encephalopathy Respiratory insufficiency Cerebral edema NAXE gene APOAIBP gene Novel variation Case report

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Accelerated Particle Swarm Optimization Algorithm for Efficient Cluster Head Selection in WSN

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Computers, Materials & Continua 2024年第6期79卷 3585-3629页

作者： Imtiaz Ahmad Tariq Hussain Babar Shah Altaf Hussain Iqtidar Ali Farman Ali institute of Computer Sciences and Information Technology The University of AgriculturePeshawarPakistan School of Computer Science and Technology Zhejiang Gongshang UniversityHangzhouChina College of Technological Innovation Zayed UniversityDubaiUnited Arab Emirates School of Computer Science and Technology Chongqing University of Posts and TelecommunicationsChongqing400065China Department of Applied AI School of ConvergenceCollege of Computing and InformaticsSungkyunkwan UniversitySeoul03063South Korea

Numerous wireless networks have emerged that can be used for short communication ranges where the infrastructure-based networks may fail because of their installation and *** of them is a sensor network with embedded sensors working as the primary nodes,termed Wireless Sensor Networks(WSNs),in which numerous sensors are connected to at least one Base Station(BS).These sensors gather information from the environment and transmit it to a BS or gathering *** have several challenges,including throughput,energy usage,and network lifetime *** strategies have been applied to get over these *** may,therefore,be thought of as the best way to solve such ***,it is crucial to analyze effective Cluster Head(CH)selection to maximize efficiency throughput,extend the network lifetime,and minimize energy *** paper proposed an Accelerated Particle Swarm Optimization(APSO)algorithm based on the Low Energy Adaptive Clustering Hierarchy(LEACH),Neighboring Based Energy Efficient Routing(NBEER),Cooperative Energy Efficient Routing(CEER),and Cooperative Relay Neighboring Based Energy Efficient Routing(CR-NBEER)*** the help of APSO in the implementation of the WSN,the main methodology of this article has taken *** simulation findings in this study demonstrated that the suggested approach uses less energy,with respective energy consumption ranges of 0.1441 to 0.013 for 5 CH,1.003 to 0.0521 for 10 CH,and 0.1734 to 0.0911 for 15 *** sending packets ratio was also raised for all three CH selection scenarios,increasing from 659 to *** number of dead nodes likewise dropped for the given combination,falling between 71 and *** network lifetime was deemed to have risen based on the results found.A hybrid with a few valuable parameters can further improve the suggested APSO-based *** to underwater,WSN can make use of the proposed *** overall results have been evaluated and

关键词： Wireless sensor network cluster head selection low energy adaptive clustering hierarchy accelerated particle swarm optimization

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Removal of Rhodamine B from aqueous solutions and wastewater by walnut shells： kinetics, equilibrium and thermodynamics studies

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Frontiers of Chemical Science and Engineering 2013年第4期7卷 428-436页

作者： Jasmin Shah M. Rasul Jan Attaul Haq Younas Khan institute of Chemical Sciences University of Peshawar Peshawar Pakistan

An adsorption study ofRhodamine B （RB） dye from aqueous solutions was carried out using walnut shells pretreated by different methods. In addition to the effects of the pretreatment, the effects of various parameters like pH, adsorbent dose, contact time, initial dye concentration and temperature on the adsorption of RB was studied. The adsorption process was highly pH dependent and a maximum adsorption was achieved at pH 3.0. The best fit for the rates of dye adsorption was a pseudo-second- order kinetic model with good correlation coefficients （R2〉 0.99）. Langmuir isotherms were used to determine that the maximum loading capacity of the different walnut shells and the RB capacities ranged from 1.451-2.292 mg ~ gl. The dye adsorption was also evaluated thermodyna- mically. Positive standard enthalpy （M-P） values were obtained indicating that the RB adsorption process is endothermic as well as AG~ and AS~ values showed that adsorption process is spontaneous with an increased randomness at the solid-liquid interface~ Desorption studies were carried out to explore the feasibility of regenerating the used walnut shells and it was found that 97~71%-99.17% of the retained RB was recovered with 0.1 mol＂ L 1 NaOH solution. The walnut shells were also successfully used to remove RB from industrial effluents.

关键词： Rhodamine B walnut shell adsorption,kinetics isotherms regeneration

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The effects of selenium on the translation efficiency of selenoproteins Gpx1， Gpx4， and Txnrd1 in oxLDL-induced ***926 cells

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Food Science and Human Wellness 2024年

作者： Jiaqi Lu Jing Meng Yanzhi Lang Abdul rehman Yamei Yan Linwu Ran School of Public Health， Ningxia medical University Key Laboratory of Environmental Factors and Chronic Disease Control Yinchuan School of Clinical Medicine， Ningxia medical University Goji Berry Research institute， Ningxia Academy of Agriculture and Forestry Sciences

Selenium is a crucial trace element that contributes to physiological processes in the body as selenoproteins. Selenoproteins serve as an integral role in the body in controlling the redox state of cells and protecting against damage induced by oxidative stress. This study aimed to investigate the effects and possible mechanism of selenium on selenoproteins expression in ***926 cells induced by oxLDL. The impact of selenium on the viability of ***926 cells was detected by the MTT method， and intracellular ROS level and mitochondrial membrane potential were assessed by fluorescent probe DCFH-DA and JC-1， respectively. RNA-seq， quantitative real-time PCR (RT-qPCR)， and western blot were used to investigate the selenoprotein expression. Selenoprotein mRNA translation efficiency was analyzed by ribosome profiling (Ribo-Seq) coupled with transcriptomics. Our data showed that selenium supplementation (0.5 μmol/L) significantly decreased ROS production， reduced mitochondrial inner membrane potential and increased the proliferative activity of ***926 cells induced by oxLDL. Moreover， The protective effects of selenium against oxLDL-induced ***926 cell injury were associated with the upregulation of the expressions of selenoproteins GPX1， GPX4， and TXNRD1. Furthermore， the expressions of selenoproteins GPX1 and GPX4 were hierarchically controlled， but the expressions of selenoproteins TXNRD1 were mainly regulated by oxLDL. Finally， Ribo-Seq coupled with transcriptomics results demonstrated that the expressions of selenoproteins GPX1， GPX4， and TXNRD1 were regulated at the translation process level. These findings suggested that selenium could have preventive effects in oxLDL induced ***926 cell injury by regulating the selenoprotein expression， and the selenoproteins expressions at the translation level in vascular endothelial cells need further study.

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Kinetics of Acid Blue 1 Adsorption from Aqueous Solution by Carbonaceous Substrate Produced from Biotic Precursor

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Chinese Journal of Chemistry 2007年第5期25卷 596-604页

作者： FAZLULLAH, Khan Bangash SULTAN, Alam IRSHAD, Ahmad institute of Chemical Sciences University of Peshawar Peshawar 25120 Pakistan National Center of Excellence in Geology University of Peshawar Peshawar 25120 Pakistan

Adsorption of acid blue 1 from aqueous solution onto carbonaceous substrate produced from the wood of Paulownia tomentosa was investigated. The samples characterized by FTIR, SEM, EDS and XRD techniques, indicated that the surface functional groups like carboxyl, lactones or phenols and ethers have disappeared at high activation temperature （800 ℃） and as a result porous structure was developed that has a positive effect on the adsorption capacity. Bangham and parabolic diffusion models were applied to the kinetic adsorption data, which show that the adsorption of acid blue 1 was a diffusion controlled process. The reaction rate increased with the increase in temperatures of both the adsorption and activation. Thermodynamic parameters like △E^≠, △H^≠, △S^≠ and △G^≠ were calculated from the kinetic data. The negative values of △S^≠ reflected the decrease in the disorder of the system at the solid-solution interface during adsorption. Gibbs free energy （△G^≠）, representing the driving force for the affinity of dye for the carbon surface, increased with the increase in sample activation and the adsorption temperatures.

关键词： activated carbon chemical treatment thermal activation adsorption functional group XRD SEM EDS FTIR

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Bacterial Spectrum and Antimicrobial Profile of Pediatric Blood Stream Infection at a Tertiary Care Hospital in Pakistan

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Chinese medical Sciences Journal 2020年第4期35卷 315-322页

作者： Anees Muhammad Sadiq Noor Khan Tahir Jamal Irshad Ul Haq Abdul Jabbar Ihsan Ali Department of medical Laboratory Technology University of HaripurHaripurKhyber Pathtunkhwa(KPK)22620Pakistan rehman medical institute(RMI) PeshawarKPK 22620Pakistan Department of Microbiology University of HaripurHaripurKPK 22620Pakistan College of medical Technology Bacha Khan Medical CollegeMardanKPK 23200Pakistan lnstitute of Paramedical Sciences Khyber Medical UniversityPeshawarKPK 22620Pakistan

Objectives Blood stream infections(BSIs)are the main cause of morbidity and mortality in children *** present study was carried out to determine the prevalence of BSI with a focus on the identification of the causative agent of BSI,and to further evaluate the antibiotic susceptibility profile of the causing bacterial *** A cross-section study was carried out at the tertiary care hospital in peshawar,Pakistan from January to December,*** samples were collected in BACTEC™botdes and standard microbiological protocols were applied for the isolation and identification of bacterial *** antibiotic susceptibility tests were performed using disc diffusion method as per the 2014 guideline of Clinical Laboratory Standard institute(CLSI).Results Of 567 blood cultures in total,111(19.6%)were positive for *** children were 64%(71/111)and female children were 36%(40/111).For the causative predominant group of microorganisms,Gramnegative bacteria were identified in 79(71.1%)isolates,and Gram-positive bacteria in 32(28.9%)*** common bacteria of isolates were ***(n=35,31.5%),***(n=19,17.1%),***(n=18,16.2%),***(n=12,10.8%),and Enterococcus species(n=7,6.3%).The 36.7%(29/79)isolates of Gram-negative bacteria were ESBL producers,and 61.1%(11/18)of *** isolates were methicillin ***,72.9%isolates were multidrug *** Gram-negative bacteria were the main cause of pediatric BSIs,where the predominant microorganism was S.卯***,majority of the *** isolates were resistant to ciprofloxacin.

关键词： antibiotic resistance blood stream infections pediatric Pakistan

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