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Efficacy of acupuncture on cancer pain:A systematic review and meta-analysis

Journal of Integrative Medicine 2024年第3期22卷 235-244页

作者： Miguel Faria Mónica Teixeira Maria João Pinto Paulo Sargento Núcleo de Investigação em Ciências e Tecnologias da Saúde Instituto Politécnico da Lusofonia1950-396 LisboaPortugal Clínica São João de deus 1700-048 LisboaPortugal REQUIMTE/LAQV(rede de Química e Tecnologia/Laboratório Associado para a Química Verde) Instituto Superior de EngenhariaInstituto Politécnico do Porto4051-401 PortoPortugal Hospital SOERAD 2560-312 Torres VedrasPortugal Centro de Estudos Avançados em Direito“Francisco Suarez ”1749-024 LisboaPortugal

Background:Pain associated with cancer is one of the greatest causes of reduced quality of life in *** is one of the treatments used to address this issue,with the great advantage of having little or no side effects,especially when compared with pharmacological ***:The aim of this systematic review and meta-analysis was to evaluate the current evidence regarding the efficacy of acupuncture for cancer *** strategy:Six electronic databases(PubMed,EBSCO,Cochrane Library,Scielo,b-On and Scopus)were searched for relevant articles about pain relief in cancer patients from their beginning until 2022using MeSH terms such as“acupuncture,”“electroacupuncture,”“ear acupuncture,”“acupuncture analgesia,”“oncological pain,”and“cancer pain.”Inclusion criteria:Studies included were randomized controlled trials(RCTs)where acupuncture was compared with no treatment,placebo acupuncture or usual *** extraction and analysis:Three independent reviewers participated in data extraction and evaluation of risk of bias,and a meta-analysis was *** primary outcome was pain intensity,measured with the visual analog scale,numeric rating scale,or brief pain *** outcomes also assessed were quality of life,functionality,xerostomia,pain interference,and analgesic *** were expressed as standardized mean difference(SMD)with 95%confidence interval(CI).Results:Sixteen RCTs with a total of 1124 participants were included in the meta-analysis,with the majority of the studies presenting a low or unclear risk of *** was more effective in reducing pain than no treatment(SMD=–0.90,95%CI[–1.68,–0.12]),sham acupuncture(SMD=–1.10,95%CI[–1.59,–0.61])or usual care(SMD=–1.16,95%CI[–1.38,–0.93]).Conclusion:The results of this study suggest that acupuncture may be an effective intervention to reduce pain associated with *** some limitations due to the low quality and small sample size of some included st

关键词： Acupuncture Cancer pain Meta-analysis Systematic review

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Effect of biochar on the metabolome of soybean seedlings

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Oil Crop Science 2024年第1期9卷 60-68页

作者： Nathalia E.Silva Mariana G.Aguilar Osania E.Ferreira Gleicia M.Paulino Jaqueline C.L.Carvalho Lúcia P.S.Pimenta Alan R.T.Machado Programa de Pos-graduaçao em Ciencias Ambientais Universidade do Estado de Minas GeraisFrutalMinas Gerais38202-436Brazil departamento de Química Universidade Federal de Minas GeraisMinas GeraisBelo Horizonte31270-901Brazil departamento de engenharia Aplicada e Tecnologias Ambientais Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil departamento de Ciencias Exatas Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil

The use of biochar can have several effects on plant germination,depending on raw material,preparation method and application ***,the molecular mechanisms that lead to those results have yet to be *** aim of this research was to improve the understanding of these mechanisms by characterizing the metabolic effects of sugarcane bagasse biochar on soybean *** types of biochars were prepared by pyrolysis at 300℃(SCB300),400℃(SCB400)and 600℃(SCB600).Then,each one was mixed into sand at 1%,3%,5%(w/w)dose,*** experiment was performed in 8 days of incubation,when the number of germinated seeds and the average radicle length were *** evaluate the metabolome,the dry biomass(DB)was subjected to extraction with a mixture of methanol-d4 and D2O(1:1 v/v).The extracts were submitted to metabolomics analysis by Proton Nuclear Magnetic *** Relative Germination,Relative Average Radicle Growth and Germination Index increased in all treatments compared to *** the other hand,the DB increased in all treatments,except for SCB300,at doses of 1%and 3%w/*** metabolites(alanine,asparagine,acetic acid,citric acid,glycerol,fatty acids and sucrose)were identified and quantified in DB extracts as the most influential finding for the separation of *** together,these results strongly suggested that biochars accelerated the catabolism of triacylglycerols to sucrose and induced a slight osmotic stress.

关键词： Germination Metabolomics 1H NMR Pyrolysis Sugarcane bagasse

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Impact Containment Barriers with Geotextile Tubes

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Journal of Geoscience and Environment Protection 2024年第5期12卷 325-344页

作者： Flávio da Silva Ornelas Luís Fernando Martins Ribeiro Rafael Cerqueira Silva Instituto Federal de Educaç &#227o Ci&#234ncia e Tecnologia&#8212IFTO Palmas Brasil departamento de engenharia Civil e Ambiental Programa de p&#243s gradua&#231&#227o em Geotecnia Universidade de Bras&#237lia&#8212UnB/Campus Universit&#225rio Darcy Ribeiro Bras&#237lia Brasil

Recently, tragic tailings dam collapses in Brazil have caused deaths and major destruction and the need to develop technologies capable of preventing damage to people and the environment. Brazilian tailings dams are in a situation of uncertainty due to new legislation that even requires decommissioning, an activity that involves many problems and where the risk of failure is the main one. An impact containment structure downstream of these dams can be effective and geotextile tubes, in a new approach, have emerged as an option with advantages in terms of execution, costs and safety. The technology is versatile and can bring many benefits such as the reuse of tailings or filling with low-energy or reused materials. In this research, geotextile tubes were tested as free containment barriers, experiencing impacts in reduced models. The safety factor for the stability of the structure was constructed using an equation which is the ratio between the self-weight of the barrier structure and its coefficient of static friction and the impact pressure, where the data showed an adequate correlation which suggests the viability of mitigating risks.

关键词： Geotextile Tube debris Flow Barriers Impact Mining

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Gravity Fault Subsidence and Beach Ridges Progradation in Quinta-Cassino (RS) Coastal Plain, Brazil

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Open Journal of Geology 2024年第2期14卷 177-195页

作者： Bruno Silva da Fontoura Adelir José Strieder Iran Carlos Stalliviere Corrêa Paulo Rogério Mendes Alexandre Felipe Bruch Angélica Cirolini Programa de Pós-Graduaç &#227o em Geoci&#234ncias (PPGeo) Instituto de Geoci&#234ncias UFRGS Porto Alegre Brazil engenharia Geológica Centro de Engenharias UFPel Pra&#231a Domingos Rodrigues 2 Pelotas Brasil HIDROSERV-Serviç os Geológicos e Geofísicos Ltda. Rua Senegal 152 Porto Alegre Brazil Colégio Politécnico UFSM Santa Maria Brasil

Ground penetrating radar (GPR) surveys have being applied to investigate very near-surface stratification of sedimentary units in coastal plains and to define their depositional conditions. This paper presents, however, low-frequency GPR survey to investigate fault-related depositional systems at greater depths. The Quinta-Cassino area in the Rio Grande do Sul Coastal Plain (RGSCP, Brazil) shows a wide strandplain that is made off by very long, continuous, and linear geomorphic features (beach ridges). This strandplain extends for ~70 km southward. The beach ridges show low-angle truncations against the Quinta escarpment, and also truncations in the strandplain. The traditional approach points that RGSCP was developed by juxtaposition of four lagoons/barrier systems as consequence of sea level changes;previous model assumes that no deformational episode occurred in RGSCP. The geophysical and geological surveys carried out in this area showed the existence of listric fault controlling the beach ridges in the escarpments and hanging-wall blocks. The radargrams could distinguish Pleistocene basement unit anticlockwise rotation, thickening of beach ridges radarfacies close to listric normal faults, and horst structures. These deformational features indicate that the extensional zone of a large-scale gravity-driven structure controlled the mechanical subsidence, the Holocene sedimentation and its stratigraphic and geomorphic features in the Quinta-Cassino area to build up an asymmetric delta. The results point to a new approach in dealing with RGSCP Holocene evolution.

关键词： Gravity Tectonics Normal Faults Ground Penetrating Radar Survey Beach-Ridges Progradation

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Adaptive Fourier decomposition of the First Three SARS-CoV-2 Infection Waves with Epidemic Intervention—London,UK,2020-2022

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China CDC weekly 2024年第21期6卷 478-486,I0006-I0008页

作者： Zige Liu Guibin Lu Cheokieng Vong Zhiqi Zeng Wei He Zhijie Lin Cuiyun Lin Kaichin Hsieh Zifeng Yang Arlindo L.Oliveira Chitin Hon department of Engineering Science Faculty of Innovation EngineeringMacao University of Science and TechnologyMacao SARChina Queen Ethelburga’s Collegiate Thorpe Underwood EstateYorkUK State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Respiratory Disease AI Laboratory on Epidemic and Medical Big Data Instrument Applications Department of Engineering ScienceFaculty of Innovation EngineeringMacao University of Science and TechnologyMacao SARChina Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases KingMed School of Laboratory MedicineGuangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Faculty of Innovation Engineering School of Computer Science and EngineeringMacao University of Science and TechnologyMacao SARChina University College London UCL Faculty of Engineering SciencesLondonUK Guangzhou Laboratory Guangzhou CityGuangdong ProvinceChina Instituto de engenharia de Sistemas e Computadores:Investigação e desenvolvimento em Lisboa LisboaPortugal Instituto Superior Técnico Universidade de LisboaLisboaPortugal

Background:This study provides a detailed analysis of the daily fluctuations in coronavirus disease 2019(COVID-19)case numbers in London from January 31,2020 to February 24,*** primary objective was to enhance understanding of the interactions among government pandemic responses,viral mutations,and the subsequent changes in COVID-19 case ***:We employed the adaptive Fourier decomposition(AFD)method to analyze diurnal changes and further segmented the AFD into novel multi-component groups consisting of one to three *** restructured components were rigorously evaluated using Pearson correlation,and their effectiveness was compared with other signal analysis *** study introduced a novel approach to differentiate individual components across various time-frequency scales using basis decomposition ***:Analysis of London’s daily COVID-19 data using AFD revealed a strong correlation between the“stay at home”directive and high-frequency components during the first epidemic *** indicates the need for sustained implementation of vaccination policies to maintain their ***:The AFD component method provides a comprehensive analysis of the immediate and prolonged impact of governmental policies on the spread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).This robust tool has proven invaluable for analyzing COVID-19 pandemic data,offering critical insights that guide the formulation of future preventive and public health strategies.

关键词： offering sustained London

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Growth of Variable Aspect Ratio ZnO Nanorods by Solochemical Processing

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Journal of Materials Science & Technology 2015年第1期31卷 10-15页

作者： Marivone Gusatti Daniel A.R.Souza Nivaldo C.Kuhnen Humberto G.Riella departamento de engenharia Química e engenharia de Alimentos Programa de Pós-Graduacao em Engenharia Química LABMAC Universidade Federal de Santa Catarina (UFSC) Campus UniversitárioCP 476 Florianópolis Santa Catarina 88040-900 Brazil

In this work,variable aspect ratio（length divided by diameter） zinc oxide nanorods were synthesized through a simple solochemical method by reacting a Zn2+precursor with sodium hydroxide at low reaction *** analysis of the X-ray diffraction data indicated that the samples had hexagonal wurtzite structure and nanometric size *** transmission electron microscopy（Tem） images of the products prepared at60 and 80 ℃ exhibited rod-like architecture,showing that the reaction temperature did not affect the ZnO *** average aspect ratio of the ZnO nanorods decreased from 3.4 to 2.4 when the reaction temperature was raised from 60 to 80 ℃.The samples presented a blue shift in the excitonic absorption compared to ZnO bulk that increased alongside with reaction *** addition,this research investigated the results obtained by varying the concentration of zinc chloride *** the same temperature,it could be verified that when the zinc concentration was increased,the diameter of the ZnO nanorods also slightly increased,and much shorter nanorods were achieved,especially in the reactions performed at 50 and 70 ℃.Finally,the growth mechanism of the ZnO nanostructures was proposed based on the results obtained by changing the zinc precursor concentration and reaction temperature.

关键词： Chemical synthesis ZnO nanorods Growth mechanism

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Morphological and molecular diversity of arbuscular mycorrhizal fungi in revegetated iron-mining site has the same magnitude of adjacent pristine ecosystems

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Journal of Environmental Sciences 2018年第5期30卷 330-343页

作者： Caroline Krug Vieira Matheus Nicoletti Marascalchi Arthur Vinicius Rodrigues Rafael Dutra de Armas Sidney Luiz Stürmer Universidade Regional de Blumenau(FURB) Programa de Pos-Graduacao em Engenharia Ambiental89030-903 BlumenauSCBrazil Universidade Regional de Blumenau(FURB) Departamento de Ciencias Naturais(DCN)89030-903 BlumenauSCBrazil Uniuersidade Regional de Blumenau(FURB) Programaa de Pos-Graduacao em Engenharia Florestal89030-903 BlumenauSCBrazil Centro Universitario-Catolica de Santa Catarina 89203-005 JoinvilleSCBrazil

Arbuscular mycorrhizal fungi（AMF） are important during revegetation of mining sites, but few studies compared AMF community in revegetated sites with pristine adjacent ecosystems. The aim of this study was to assess AMF species richness in a revegetated iron-mining site and adjacent ecosystems and to relate AMF occurrence to soil chemical parameters. Soil samples were collected in dry and rainy seasons in a revegetated iron-mining site（RA） and compared with pristine ecosystems of forest（FL）, canga（NG）,and Cerrado（CE）. AMF species were identified by spore morphology from field and trap cultures and by LSU r DNA sequencing using Illumina. A total of 62 AMF species were recovered, pertaining to 18 genera and nine families of Glomeromycota. The largest number of species and families were detected in RA, and Acaulospora mellea and Glomus sp1 were the most frequent species. Species belonging to Glomeraceae and Acaulosporaceae accounted for 42%–48% of total species richness. Total number of spores and mycorrhizal inoculum potential tended to be higher in the dry than in the rainy season, except in RA. Sequences of uncultured Glomerales were dominant in all sites and seasons and five species were detected exclusively by DNA-based identification. Redundancy analysis evidenced soil p H,organic matter, aluminum, and iron as main factors influencing AMF presence. In conclusion, revegetation of the iron-mining site seems to be effective in maintaining a diverse AMF community and different approaches are complementary to reveal AMF species, despite the larger number of species being identified by traditional identification of field spores.

关键词： Community structure Glomeromycota Illumina LSU rDNA Spore morphology Taxonomic distinctness index

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Remarks on the application of two-dimensional shape factors under severe wear conditions

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Friction 2016年第1期4卷 65-71页

作者： Giuseppe PINTAUde Mario COSEGLIO Programa de Pós-Gradua(a)(a)o em engenharia Mec(a)nica e de Materiais UTFPR Curitiba PR Brazil University of Birmingham Birmingham UK

The use of two-dimensional shape parameters to characterize abrasive particles is a potential approach to express their angularity. Nevertheless, in sliding abrasion, especially in pin abrasion testing, these descriptors could not be suitable for characterizing severe wear of engineering materials such as steels and cast irons. This work compares the applicability of two-dimensional shape parameters in describing severe wear of metals in recent pin abrasion tests with cases where they could have been correlated with the wear rates. Considering these aspects, this work puts in evidence the importance of clogging occurrence and the coated paper structure for a carefully application of shape parameters. In addition, it is proposed a possible relation between the shape parameters and one of the components of the abrasion factor.

关键词： wear particle shape sliding abrasion coated papers

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An Inexact Proximal Method with Proximal Distances for Quasimonotone Equilibrium Problems

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Journal of the Operations Research Society of China 2017年第4期5卷 545-561页

作者： Lennin Mallma Ramirez Erik Alex Papa Quiroz P.R.Oliveira Coordenação dos Programas de Pós-gaduação em engenharia-Programa de engenharia de Sistemas e Computação Federal University of Rio de JaneiroRio of JaneiroBrazil Mayor de San Marcos National University LimaPeru

In this paper,we propose an inexact proximal point method to solve equilibrium problems using proximal distances and the diagonal *** some natural assumptions on the problem and the quasimonotonicity condition on the... 详细信息

关键词： Equilibrium problems Quasimonotonicity Proximal distance Proximal method

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Functionalization of AuMSS nanorods towards more effective cancer therapies

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Nano Research 2019年第4期12卷 719-732页

作者： Carolina F. Rodrigues Telma A. Jacinto Andre F. Moreira Elisabete C. Costa Sonia P. Miguel Ilidio J. Correia CICS-UBI -Centro de Investigagao em Ciencias da Saude Universidade da Beira Interior Covilhd 6200-506 Portugal CIEPQF - departamento de engenharia Quimica Universidade de Coimbra Rua 13 Silvio Lima Coimbra 3030-790 Portugal

The applicatio n of nano particles as selective drug delivery platforms arises as one the most promising therapeutic strategies in the biomedical field. Such systems can encapsulate drugs, prevent its premature degradation, transport and promote the drugs specific delivery to the target site. Among the different nanostructures, gold-core mesoporous silica shell (AuMSS) nanorods have been one of the most explored due to their unique physical and chemical properties. The mesoporous silica biocompatibility, high surface area that can be easily functionalized, tubular pores that can store the drugs, conjugated with the intrinsic capacity of gold nanorod to absorb near-infrared radiation, allows the combination of hyperthermia (i.e., photothermal effect) with drug delivery, making them a nanoplatforms with a huge potential for cancer therapy. Nevertheless, the successful applicati on of AuMSS nanoparticles as an effective can cer nano medicine is hindered by the uncon trolled release of the therapeutic payloads, limited blood circulation time and unfavorable pharmacokinetics. In this review, an overview of the modificati ons performed to improve the AuMSS nano rods applicati on in nanom edicine is provided, highlighting the practical approaches that enhaneed the AuMSS nanorods targeting, responsiveness to different stimuli, and blood circulation time. Further, the basics of AuMSS nano rods syn thesis procedures, gen eral properties, and its applicati on in can cer therapy are also described.

关键词： gold nano rods silica surface modifications targeting cancer

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