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Primary coexisting adenocarcinoma of the colon and neuroendocrine tumor of the duodenum: A case report and review of the literature

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2724-2734页

作者： Song Fei Wei-Dong Wu Han-Shuo Zhang Shao-Jie Liu Dan Li Bo Jin Department of Thoracic and Cardiovascular Surgery Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Department of Gastrointestinal Surgery Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Neuroendocrine tumors(NETs)arise from the body’s diffuse endocrine *** primary adenocarcinoma of the colon and NETs of the duodenum(D-NETs)is a rare occurrence in clinical *** classification and treatment criteria for D-NETs combined with a second primary cancer have not yet been *** SUMMARY We report the details of a case involving female patient with coexisting primary adenocarcinoma of the colon and a D-NET diagnosed by imaging and surgical *** tumors were treated by surgery and four courses of *** patient achieved a favorable clinical *** Coexisting primary adenocarcinoma of the colon and D-NET were diagnosed by imaging,laboratory indicators,and surgical *** resection com-bined with chemotherapy was a safe,clinically effective,and cost-effective treat-ment.

关键词： Neuroendocrine tumor of the duodenum Multiple primary tumors Colorectal cancer Endoscopic resection Case report

Enhancing clinical proficiency through laparoscopic training using Japanese origami

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第3期7卷 102-106页

作者： Shunsuke Furukawa Masatsugu Hiraki Naoya Kimura Ryota Sakurai Ryo Kohata Naohiko Kohya Masashi Sakai Akashi Ikubo Ryuichiro Samejima Department of Surgery Japanese Red Cross Society Karatsu Red Cross HospitalSaga847-8588Japan Department of Surgery Saga University Faculty of MedicineSaga849-8501Japan

Objective This study aimed to investigate the clinical efficacy of laparoscopic training using origami,a traditional Japanese papercraft,using laparoscopic forceps to create origami *** In this retrospective study,4 surgeons were randomly divided into 2 groups:The training group,consisting of surgeons 1 and 2,and the non-training group,consisting of surgeons 3 and *** the course of a one-year study period,the training group regularly underwent laparoscopic surgery training with a dry box,wherein they folded a total of 1000 origami cranes using laparoscopic *** non-training group periodically underwent common laparoscopic surgery training of techniques such as suturing and *** surgeon regularly performed the transabdominal preperitoneal approach for inguinal *** training was conducted concurrently with the *** procedure time(peritoneum detachment,mesh placement,and closure of the peritoneum),total operation time(time from peritoneum detachment to closure of the peritoneum),and surgical outcomes were *** The training group showed greater improvement in the total operation time and more stable performance than the non-training ***,the time taken for peritoneum detachment was significantly shorter in the training *** Laparoscopic training using origami has the potential to enhance laparoscopic surgical skills and improve surgical outcomes.

关键词： Laparoscopic surgery Training Dry box Origami

How Can Practitioners Support Citizen Volunteers in Disaster Risk reduction? Insight from “Good and Ready” in Aotearoa New Zealand

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International Journal of Disaster Risk Science 2024年第3期15卷 374-387页

作者： Lo?c Le Dé Steve Ronoh Ei Mon Thinn Kyu Brigitte Rive School of Public Health and Interdisciplinary Studies Auckland University of Technology Pacific Health Research Centre Auckland University of Technology New Zealand red cross

Global and national policy frameworks emphasize the importance of people's participation and volunteers' role in disaster risk reduction. While research has extensively focused on volunteers in disaster response and recovery, less attention has been paid on how organizations involved in disaster risk management can support volunteers in leading and coordinating communitybased disaster risk reduction. In 2019, the New Zealand red cross piloted the Good and Ready initiative in Auckland,Aotearoa New Zealand, with the objective to empower local people in resilience building with a focus on volunteers and community participation. This research examined the positive and negative outcomes of Good and Ready and investigated volunteers' experiences in the disaster resilience initiative. It involved the codesign of a questionnaire-based survey using participatory methods with Good and Ready volunteers, the dissemination of the survey to gather volunteers' viewpoints, and a focus group discussion with participatory activities with red cross volunteers. The findings highlight that a key challenge lies in finding a balance between a program that provides flexibility to address contextual issues and fosters communities' ownership, versus a prescriptive and standardized approach that leaves little room for creativity and self-initiative. It pinpoints that supporting volunteers with technical training is critical but that soft skills training such as coordinating, communicating,or facilitating activities at the local level are needed. It concludes that the sustainability of Good and Ready requires understanding and meeting volunteers' motivations and expectations and that enhancing partnerships with local emergency management agencies would strengthen the program.

关键词： Community-based approach Disaster risk reduction New Zealand Participation Volunteers

Identification of breath volatile organic compounds to distinguish pancreatic adenocarcinoma,pancreatic cystic neoplasm,and patients without pancreatic lesions

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 894-906页

作者： Kasenee Tiankanon Nuttanit Pungpipattrakul Thanikan Sukaram Roongruedee Chaiteerakij Rungsun Rerknimitr Division of Gastroenterology Faculty of MedicineChulalongkorn UniversityBangkok 10330Thailand center of Excellence for Innovation and Endoscopy in Gastrointestinal Oncology King Chulalongkorn Memorial HospitalThai Red Cross SocietyBangkok 10330Thailand

BACKGROUND Volatile organic compounds(VOCs)are a promising potential biomarker that may be able to identify the presence of *** To identify exhaled breath VOCs that distinguish pancreatic ductal adenocar-cinoma(PDAC)from intraductal papillary mucinous neoplasm(IPMN)and healthy *** We collected exhaled breath from histologically proven PDAC patients,radiological diagnosis IPMN,and healthy volunteers using the ReCIVA®device between 10/2021-11/*** were identified by thermal desorption-gas chromatography/field-asymmetric ion mobility spectrometry and compared between *** A total of 156 participants(44%male,mean age 62.6±10.6)were enrolled(54 PDAC,42 IPMN,and 60 controls).Among the nine VOCs identified,two VOCs that showed differences between groups were dimethyl sulfide[0.73 vs 0.74 vs 0.94 arbitrary units(AU),respectively;P=0.008]and acetone dimers(3.95 vs 4.49 vs 5.19 AU,respectively;Pred to controls and IPMN(aOR:5.12(1.80-14.57)and aOR:3.35(1.47-7.63),respectively(Pred to validate these findings.

关键词： Volatile organic compound Pancreas Adenocarcinoma Pancreatic intraductal neoplasms Breathing

Multiple paradoxical embolisms caused by central venous catheter thrombus passing through a patent foramen ovale: A case report

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World Journal of Clinical Cases 2024年第4期12卷 842-846页

作者： Jian-Duan Li Nian Xu Qiang Zhao Biao Li Li Li Department of Cardiology Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510235Guangdong ProvinceChina

BACKGROUND To date,this is the first case of a paradoxical embolism(PDE)that concurrently manifested in the coronary and lower limb arteries and was secondary to a central venous catheter(CVC)thrombus via a patent foramen ovale(PFO).CASE SUMMARY Here,we report a case of simultaneous coronary and lower limb artery embolism in a PFO patient carrier of a *** patient presented to the hospital with acute chest pain and lower limb *** ultrasound showed a large thrombus in the right internal jugular vein,precisely at the tip of the *** and transesophageal echocardiography confirmed the existence of a PFO,with inducible right-to-left shunting by the Valsalva *** patient was administered an extended course of anticoagulation therapy,and then the CVC was successfully *** PFO closure was not *** was no recurrence during *** Thus,CVC-associated thrombosis is a potential source for multiple PDE in PFO patients.

关键词： Paradoxical embolism Central venous catheter Patent foramen ovale Acute myocardial infarction Case report

The Association between Fear of COVID-19,Obsession with COVID-19,and Post Traumatic Stress Disorder in Korean Emergency Rescue Firefighters:A cross-Sectional Study

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International Journal of Mental Health Promotion 2024年第6期26卷 475-480页

作者： Yun-Jung Choi Heewon Song red cross College of Nursing Chung-Ang UniversitySeoulSouth Korea Department of Nursing Chung-Ang UniversitySeoulSouth Korea

During the rapid spread of COVID-19,first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of *** uncertainty can have adverse mental health effects,such as increased anxiety and *** study aimed to investigate the degree of association between fear of COVID-19,obsession with COVID-19,and post-traumatic stress disorder(PTSD)in emergency rescue *** participants were 150 emergency rescue firefighters working in Region S,*** filled out self-report questionnaires:The data obtained through the Fear of COVID-19 Scale,Obsession with COVID-19 Scale,and Impact of Event Scale-Revised Korean version were subjected to nonparametric statistical analysis using SPSS WIN *** study found a significant correlation between emergency rescue firefighters’fear of COVID-19,obsession with COVID-19,and *** and obsession with COVID-19 were higher among first responder firefighters who were directly involved in COVID-19-related ***,a one-point increase in obsession was associated with a 2.837-point increase in *** on the results,we found that there is a need for effective control of obsessions and fears among first responder firefighters during COVID-19,and we suggest that there is a need for mental health care for first responder firefighters during the pandemic through the development and support of programs to prevent and mitigate obsessions.

关键词： COVID-19 emergency rescue firefighters fear of COVID-19 mental health promotion obsession with COVID-19 PTSD

Analysis of the Clinical Efficacy of Glimepiride Combined with Insulin in the Treatment of Elderly Diabetes

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Journal of Clinical and Nursing Research 2024年第9期8卷 24-29页

作者： Chun Feng Qinghai red cross Hospital Xining 810000Qinghai ProvinceChina

Objective:To explore the clinical efficacy and incidence of hypoglycemia in the treatment of elderly diabetes with glimepiride combined with ***:A total of 100 patients diagnosed with diabetes in Qinghai red cross Hospital from January 2018 to January 2019 were selected and divided into an observation group and a control group according to the order of their visits,with 50 patients in each *** observation group was treated with glimepiride combined with insulin,while the control group was treated with insulin *** blood sugar indicators,including glycated hemoglobin(HbA1c),fasting blood glucose(FBG),and 2-hour postprandial blood glucose(2h PBG),were compared between the two ***,the incidence of hypoglycemia was compared,and the causes of hypoglycemia were analyzed and summarized,proposing corresponding ***:The glycated hemoglobin value of the observation group was lower than that of the control group,and the statistical analysis showed a significant difference(t=3.54,Pblood glucose value in the observation group was lower than that in the control group,with statistically significant differences(t=4.08,Pblood glucose value in the observation group was also lower than that in the control group,with a significant difference(t=3.82,P<0.05).The incidence of hypoglycemia in the observation group was 10%,while it was 56%in the control group,with a statistically significant difference between the two groups(χ^(2)=5.813,P<0.05).Conclusion:The efficacy of glimepiride combined with insulin in the treatment of elderly diabetes is significantly higher than that of insulin alone,with a lower incidence of hypoglycemia.

关键词： Diabetes Glimepiride Insulin Hypoglycemia

MicroRNAs in thyroid cancer with focus on medullary thyroid carcinoma:potential therapeutic targets and diagnostic/prognostic markers and web based tools

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Oncology Research 2024年第6期32卷 1011-1019页

作者： ELHAM SHAKIBA SETI BOROOMAND SIMA KHERADMAND KIA MEHDI HEDAYATI Department of Biochemistry Faculty of Biological SciencesNorth Tehran BranchIslamic Azad UniversityTehran***Iran Department of Pathology and Laboratory Medicine Vancouver General HospitalVancouverV5Z 1M9Canada Department of blood Cell Research Laboratory for Red Blood Cell DiagnosticsSanquinAmsterdam1006 ANThe Netherlands Cellular and Molecular Endocrine Research center Research Institute for Endocrine SciencesShahid Beheshti University of Medical SciencesTehran***Iran

This review aimed to describe the inculpation of microRNAs(miRNAs)in thyroid cancer(TC)and its subtypes,mainly medullary thyroid carcinoma(MTC),and to outline web-based tools and databases for bioinformatics analysis of miRNAs in ***,the capacity of miRNAs to serve as therapeutic targets and biomarkers in TC management will be *** review is based on a literature search of relevant articles on the role of miRNAs in TC and its subtypes,mainly ***,web-based tools and databases for bioinformatics analysis of miRNAs in TC were identified and *** can perform as oncomiRs or antioncoges,relying on the target mRNAs they *** replacement therapy using miRNA mimics or antimiRs that aim to suppress the function of certain miRNAs can be applied to correct miRNAs aberrantly expressed in diseases,particularly in *** are involved in the modulation of fundamental pathways related to cancer,resembling cell cycle checkpoints and DNA repair *** are also rather stable and can reliably be detected in different types of biological materials,rendering them favorable diagnosis and prognosis biomarkers as *** have emerged as promising tools for evaluating medical outcomes in TC and as possible therapeutic *** contribution of miRNAs in thyroid cancer,particularly MTC,is an active area of research,and the utility of web applications and databases for the biological data analysis of miRNAs in TC is becoming increasingly important.

关键词： Thyroid cancer MicroRNAs Biomarker Bioinformatics analysis Medullary thyroid carcinoma(MTC) OncomiRs Antioncoges

Epidemiology of work-related hand and wrist injuries in a referral center: A descriptive study

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World Journal of Orthopedics 2024年第7期15卷 650-659页

作者： Angélica M Rodríguez Ginna P Tocanchón Jessica T Villalba Luis M Pombo Aníbal A Teherán Gabriel Camero-Ramos Karen P Ayala Gerhard M Acero Research center Fundación Universitaria Juan N.CorpasBogotá111321Colombia red cross Cruz Roja Colombiana-Seccional Cundinamarca BogotáBogotá111221Colombia Vigilancia Epidemiológica Instituto Nacional de SaludBogotá111321Colombia

BACKGROUND Occupational hand and wrist injuries(OHWIs)account for 25%of work-related accidents in low-and middle-income *** Colombia,more than 500000 occupational accidents occurred in 2021,and although the rate declined to less than 5%in 2020 and 2021,at least one in four accidents involved a hand or wrist *** To describe the OHWIs in workers seen at the emergency room at a second-level hospital in *** An observational study was performed using data from workers who experienced OHWIs and attended a second-level hospital,between June,2020 and May,*** overall frequency of OHWIs,as well as their distribution by sociodemo-graphic,clinical,and occupational variables,are ***,association patterns between sex,anatomical area(fingers,hand,wrist),and type of job were analyzed by correspondence analysis(CA).RESULTS There were 2.101 workers treated for occupational accidents,423(20.3%)were cases of OHWIs,which mainly affected men(93.9%)with a median age of 31 years and who worked mainly in mining(75.9%).OHWIs were more common in the right upper extremity(55.3%)and comprised different types of injuries,such as contusion(42.1%),laceration(27.9%),fracture(18.7%),and crush injury(15.6%).They primarily affected the phalanges(95.2%),especially those of the first finger(25.7%).The CAs showed associations between the injured anatomical area and the worker’s job that differed in men and women(explained variance>90%).CONCLUSION One out of five workers who suffered occupational accidents in Cundinamarca,Columbia had an OHWI,affecting mainly males employed in *** occupational profile is likely to lead to prolonged rehabilitation,and permanent functional *** results might be useful for adjusting preventive measures in cluster risk groups.

关键词： Accidents Occupational Epidemiology Hand injuries Wrist injuries Occupational health