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Regulatory effect of substance P on hypothalamus-pituitary-testes axis

Neural Regeneration Research 2006年第7期1卷 665-667页

作者： Weihong Li Enkui Jiang Zhijie Chang department of Physiology Liaoning Medical UniversityJinzhou 121001Liaoning ProvinceChina Department of PhysiologyLiaoning Medical UniversityJinzhou 121001Liaoning ProvinceChina Department of PhysiologyLiaoning Medical UniversityJinzhou 121001Liaoning ProvinceChina

BACKGROUND: Most of the studies about the regulation effect of substance P (SP) on reproductive axis involve female and few are about male. The effect of SP on the regulation of hypothalamus-pituitary-testes axis is unclear. OBJECTIVE: To observe the effect of SP on gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH) and testosterone(T) in hypothalamus-adenohypophysis-testes cells. DESIGN: Controlled observation. SETTING: department of Physiology and department of Nuclear Medicine, Liaoning Medical University. MATERIALS: Ten healthy male SD rats, of common grade, weighing from 230 to 250 g, were provided by the Experimental Animal Center of Liaoning Medical University. SP (Sigma, USA); LH and T radioimmunoassay kit (Nuclear Medical Technology Center of Tianjin radiology Medical College); γ-immunology counter (state-run 262 Plant);all-purpose refrigerated centrifuge (DLL-4A, Dachang Medical Instrument Factory, Jiangsu). METHODS: This experiment was carried out in the department of Physiology and department of Nuclear Medicine, Liaoning Medical College in January 1997. The SD rats were raised at room temperature. One week later, hypothalamus tissue and adenohypophysis were separated. Abdominal cavity was cut open to take out bilateral testicles. The tegument was removed. The 3 kinds of tissues were cultured by cell culture technology separately. The cells of hypothalamus-adenohypophysis-testes were perfused with100 mg/L SP as follows: hypothalamus-adenohypophysis (the first group); hypothalamus (SP)-adenohypophysis (the second group); hypothalamus-adenohypophysis (SP) (the third group); adenohypophysis-testes (the fourth group); adenohypophysis-testes(SP) (the fifth group). The content of LH in adenopituicyte culture fluid and T in testes culture fluid were measured with radioimmunoassay. MAIN OUTCOME MEASURES: SP was perfused into the culture fluid of hypothalamus-adenohypophysis, then the content of LH in the adenopituicyte culture fluid and T in the tes

关键词： In EK

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Surgical management of high-grade pancreatic injuries: Insights from a high-volume pancreaticobiliary specialty unit

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 834-846页

作者： Juanita Noeline Chui Krishna Kotecha Tamara MH Gall Anubhav Mittal Jaswinder S Samra department of Upper Gastrointestinal Surgery Royal North Shore HospitalSydney 2065NSWAustralia Faculty of Medicine and Health University of SydneySydney 2006NSWAustralia department of Surgery University of Notre DameSydney 2006NSWAustralia

BACKGROUND The management of high-grade pancreatic trauma is *** To review our single-institution experience on the surgical management of blunt and penetrating pancreatic *** A retrospective review of records was performed on all patients undergoing surgical intervention for high-grade pancreatic injuries [American Association for the Surgery of Trauma(AAST) Grade Ⅲor greater] at the Royal North Shore Hospital in Sydney between January 2001 and December 2022. Morbidity and mortality outcomes were reviewed, and major diagnostic and operative challenges were *** Over a twenty-year period, 14 patients underwent pancreatic resection for highgrade injuries. Seven patients sustained AAST Grade Ⅲinjuries and 7 were classified as Grades Ⅳ or Ⅴ. Nine underwent distal pancreatectomy and 5 underwent pancreaticoduodenectomy(PD). Overall, there was a predominance of blunt aetiologies(11/14). Concomitant intra-abdominal injuries were observed in 11 patients and traumatic haemorrhage in 6 patients. Three patients developed clinically relevant pancreatic fistulas and there was one in-hospital mortality secondary to multi-organ failure. Among stable presentations, pancreatic ductal injuries were missed in two-thirds of cases(7/12) on initial computed tomography imaging and subsequently diagnosed on repeat imaging or endoscopic retrograde cholangiopancreatography. All patients who sustained complex pancreaticoduodenal trauma underwent PD without mortality. The management of pancreatic trauma is evolving. Our experience provides valuable and locally relevant insights into future management *** We advocate that high-grade pancreatic trauma should be managed in high-volume hepatopancreato-biliary specialty surgical units. Pancreatic resections including PD may be indicated and safely performed with appropriate specialist surgical, gastroenterology, and interventional radiology support in tertiary centres.

关键词： Pancreas Trauma Injury Pancreatectomy Pancreaticoduodenectomy Damage control surgery

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利用MR细胞示踪技术评价由VLA-4归巢受体介导的神经胶质前体细胞对炎症组织趋向性的研究

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国际医学放射学杂志 2012年第6期 590-590页

作者： M.Gorelik I.Orukari S.Galpoththawela H.Kim M.Levy 史佳培 department of radiology and Radiological Science Division of MR ResearchThe Johns Hopkins University School of Medicine733 N BroadwayBroadway Research BuildingRoom 649BaltimoreMD 21205

摘要目的探讨神经胶质前体细胞在超表达的VLA-4介导下对炎症脑组织是否具有趋向性,以及动脉内注射MR细胞示踪技术是否能监测此归巢过程。材料与方法本实验性研究的期限为2010年8月-2012年2月,

关键词：细胞示踪 MR 归巢 VLA-4 前体细胞神经胶质胶质细胞受体介导趋向性

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Chinese Journal of Traumatology 2021年第4期24卷 221-230页

作者： Lu-Na Sun Jing-Wen Gu Li-Jun Huang Zhi-Lei Shang Yao-Guang Zhou Li-Li Wu Yan-Pu Jia Nian-Qi Liu Wei-Zhi Liu Lab for Post-traumatic Stress Disorder Faculty of Psychology and Mental HealthNaval Medical UniversityShanghai200433China The Emotion&Cognition Lab Faculty of Psychology and Mental HealthNaval Medical UniversityShanghai200433China The Battalion 3 of Cadet Brigade School of Basic MedicineNaval Medical UniversityShanghai200433China department of radiology Changshu Hospital Affiliated to Suzhou UniversityChangshu215500Jiangsu ProvinceChina

Purpose:Posttraumatic stress disorder(PTSD)is a significant global mental health concern,especially in the *** study aims to estimate the efficacy of mindfulness meditation in the treatment of military-related PTSD,by synthesizing evidences from randomized controlled ***:Five electronic databases(Pubmed,EBSCO Medline,Embase,PsychINFO and Cochrane Library)were searched for randomized controlled trials focusing on the treatment effect of mindfulness meditation on military-related *** selection of eligible studies was based on identical inclusion and exclusion *** about study characteristics,participant characteristics,intervention details,PTSD outcomes,as well as potential adverse effects was extracted from the included *** of bias of all the included studies was critically assessed using the Cochrane Collaboration's tool.R Statistical software was performed for data ***:A total of 1902 records were initially identified and *** duplicates removal and title&abstract review,finally,19 articles in English language with 1326 participants were included through strict inclusion and exclusion *** results revealed that mindfulness meditation had a significantly larger effect on alleviating military-related PTSD symptoms compared with control conditions,such as treatment as usual,present-centered group therapy and PTSD health education(standardized mean difference(SMD)=-0.33;95%CI[-0.45,-0.21];pinterventions with different control conditions(active or non-active control,SMD=-0.33,95%CI[-0.46,-0.19];SMD=-0.49,95%CI[-0.88,-0.10],respectively),formats of delivery(group-based or individual-based,SMD=-0.30,95%CI[-0.42,-0.17],SMD=-0.49,95%CI[-0.90,-0.08],respectively)and intervention durations(short-term or standard duration,SMD=-0.27,95%CI[-0.46,-0.08],SMD=-0.40,95%CI[-0.58,-0.21],respectively)were equally effective in improving military-related PTSD ***:Finding

关键词： Posttraumatic stress disorder Military personnel Mindfulness meditation Meta-analysis

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Visual representation of ASUU strikes in Nigeria:a semiotic analysis of cartoons in selected Nigerian newspapers

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Language and Semiotic Studies 2023年第2期9卷 242-262页

作者： Peter Oyewole Makinde department of Linguistics Faculty of ArtsNnamdi Azikiwe UniversityAwkaAnambra StateNigeria

Until recently,the study of language and meaning of cartoons,the media discourses they generate,and their analysis as a creative means of exploring meaning-making processes as semiotic resources have not received much scholarly attention in *** cartoons that involve the use of satire and humour as visual representations of reality have gained prominence across many media platforms in Nigeria,only a few scholars have examined this from a social semiotics *** has created a gap in the literature,thus creating room for a para-digm shift in the field of social *** study explores the semiotics of car-toons in selected Nigerian newspapers to examine the meaning-making resources employed in the visual representation of ASUU strikes in *** study,there-fore,examines how cartoonists manipulate symbols,signs,and other semiotic resources to convey specific meanings through visual and textual *** study adopts a qualitative research design;data comprising cartoons sourced from selected Vanguard Newspapers and websites are analyzed using Kress and Van Leeuwen's visual semiotics and interpreted from the standpoints of Halliday's Systematic Functional Linguistics(SFL)approach and O'Halloran's position on metaphorical constructions of ***,metaphorical manipulation and rep-resentation of visual elements in the selected cartoons are *** from the study show the use of semiotic resources in the portrayer of reality in the context of the seemingly intractable ASUU strikes and their consequences on aca-demic activities in *** scholarly intervention deserves attention as it significantly contributes to the field of social semiotics through its visual represen-tation in portraying challenges faced by the educational systems in Nigeria vis-a-vis poorgovernment funding.

关键词： 2022 ASUU strike cartoons Nigeria SFL social semiotics visual representation

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CT、MRI和FDG正电子发射体层成像在外阴恶性肿瘤治疗中的应用价值

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国际医学放射学杂志 2015年第4期 389-389页

作者： G.Lin C.Y.Chen F.Y.Liu L.Y.Yang H.J.Huang Y.T.Huang 刘春明 department of Medical Imaging and intervention Chang Gung Memorial Hospital and Chang Gung University College of Medicine

摘要目的前瞻性评估CT或MRI(CT/MRI)和PET在外阴恶性肿瘤治疗中的应用价值。方法对所有病人行腹部和盆腔的CT或MRI检查及全身的18F-FDG PET或PET/CT

关键词：外阴恶性肿瘤 PET FDG MRI 应用价值 CT

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胰腺导管腺癌放射学报告模版:腹部放射协会和美国胰腺癌协会的共识声明

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国际医学放射学杂志 2014年第2期 167-167页

作者： M.M.Al-Hawary I.R.Francis S.T.Chari E.K.Fishman D.M.Hough D.S.Lu 余晓 department of radiology University of Michigan Health System 1500 E Medical Center Dr University Hospital Room B1 D502 Ann ArborMI 48109

目的胰腺导管腺癌是一种具有侵袭性的、高死亡率的恶性肿瘤。通过放射学检查对其进行分期来合理判断疾病的严重程度是制定治疗方案的重要步骤。考虑到医生在专

关键词：胰腺导管腺癌胰腺癌腹部躯干放射学美国美利坚合众国北美洲声明

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Arterial spin labeling in neuroimaging

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World Journal of radiology 2010年第10期2卷 384-398页

作者： Sasitorn Petcharunpaisan Joana Ramalho Mauricio Castillo Division of Neuroradiology University of North Carolina at Chapel HillRoom 3326Old Infirmary BuildingManning DriveChapel HillNC 27599-7510United States department of radiology King Chulalongkorn Memorial Hospital1873 Rama IV RoadPathumwanBangkok10330Thailand department of Neuroradiology Centro Hospitalar de Lisboa CentralEPERua JoséAntónio Serrano1150-199 LisbonPortugal

Arterial spin labeling(ASL) is a magnetic resonance imaging technique for measuring tissue perfusion using a freely diffusible intrinsic *** compared with other perfusion techniques,ASL offers several advantages and is now available for routine clinical practice in many *** noninvasive nature and ability to quantitatively measure tissue perfusion make ASL ideal for research and clinical *** technical advances have increased its sensitivity and also extended its potential *** review focuses on some basic knowledge of ASL perfusion,emerging techniques and clinical applications in neuroimaging.

关键词： Arterial spin labeling Continuous arterial spin labeling Pulsed arterial spin labeling Pseudocontinuous arterial spin labeling Velocity-selective arterial spin labeling Territorial arterial spin labeling Arterial spin labeling at multiple inversion times Perfusion-based functional magnetic resonance imaging

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运用心脏低辐射剂量CT评估心肌间质纤维化的细胞外体积分数

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国际医学放射学杂志 2012年第6期 583-583页

作者： M.S.Nacif N.Kawel J.J.Lee A.Zavodni 卢平明郑晶晶 department of radiology and Imaging Sciences National Institutes of Health Clinical Center10 Center DrBldg 10Room 1C355BethesdaMD 20892-1182

摘要目的优化心脏CT扫描方法来获取细胞外体积(ECV)分数,将心脏MR成像作为参考标准。材料与方法该研究经制度审查委员会批准,且参与者签署了知情同意书。行心脏CT和心脏MR检查对健康受试者和心力衰竭病人的ECV进行测量

关键词：心肌 ECV MR 心脏细胞外 CT

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Delayed asymptomatic progressive aortic dissecting aneurysm in patient with STEMI

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Journal of Geriatric Cardiology 2017年第6期14卷 425-426页

作者： Yun-Seok Song Sang-Hoon Seol Dong-Kie Kim Ki-Hun Kim Doo-Il Kim Division ofCardiology Department of Internal Medicine Inje University College of Medicine Haeundae Paik hospital Busan South Korea

An 80-year-old woman visited emergency room because of resting chest pain for one hour. She had history of hypertension for 10 years. The blood pressure was 80/50 mmHg and the pulse rate was 51 beats/min. The electrocardiogram demonstrated Junctional bradycardia and ST elevation in lead Ⅱ, Ⅲ and aVF. Chest X-ray indicated cardiomegaly （Figure 1A）. Coronary angiography revealed near total occlusion of proximal right coronary artery （RCA）. She underwent percutaneous coronary intervention （PCI） for the RCA lesion successfully. Echocardiography showed hypokinesia of RCA territory （Figure 2A）.

关键词： Delayed Dissecting aneurysm STEMI

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