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Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities

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World Journal of Gastroenterology 2017年第25期23卷 4624-4631页

作者： Guang-Lan Chen Ye Zhang Wang-Yue Wang Xue-Liang Ji Fei Meng Pei-Song Xu Ning-Min Yang Fu-Qiang Ye Xiao-Chen Bo Department of Gastroenterology Lishui People's Hospital Department of Research service Zhiyuan Medical Inspection Institute Co. LTD Department of radiation Toxicology and Oncology Beijing Institute of Radiation Medicine People's Republic of China

AIM To investigate alterations in the fecal microbiome using 16 S r RNA amplicon sequencing in couples in the same cohabitation *** Fecal samples were collected from eight ulcerative colitis(UC) patients and their healthy partners at Lishui People's Hospital, Zhejiang Province, China. DNA was extracted and the variable regions V3 and V4 of the 16 S r RNA genes were PCR amplified using a two-step protocol. Clear reads were clustered into operational taxonomic units(OTUs) at the 97% sequence similarity level using UCLUST v1.2.22. The Wilcoxon rank-sumtest(R v3.1.2) was used to compare inter-individual differences. Differences with a P value < 0.05 were considered statistically *** Fecal microbial communities were more similar among UC patients than their healthy partners(P = 0.024). UC individuals had a lower relative abundance of bacteria belonging to the Firmicutes, especially Blautia, Clostridium, Coprococcus and Roseburia(P < 0.05). Microbiota dysbiosis was detected in UC patients and their healthy partners. Relevant genera included Akkermansiam, Bacteroides, Escherichia, Lactobacillales, Klebsiella and Parabacteroides. The enriched pathways in fecal samples of UC patients were related to lipid and nucleotide metabolism. Additionally, the pathways involved in membrane transport and metabolism of cofactors and vitamins were more abundant in the healthy *** Our results suggested that the microbial composition might be affected in healthy partners cohabiting with UC patients, especially in terms of microbiota dysbiosis.

关键词： Ulcerative colitis Patients Healthy partner Fecal microbial communities Microbiota dysbiosis

Positive Associations between Bilateral High-Frequency Hearing Loss and Hypertension Risk in Short-Term Occupational Noise Exposure

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Biomedical and Environmental Sciences 2021年第12期34卷 992-997页

作者： JIN Nan ZHONG Hui Yun YUAN Fang DENG Hua Xin Department of Occupational Health and radiation Health Chongqing Center for Disease Control and PreventionChongqing 400042China Xiejiawan Street Community Health service Center Chongqing 400042China

Noise is one of the most common occupational hazards worldwide[1], and millions of workers are exposed to harmful levels of noise in the workplace[2]. Noise-induced hearing loss(NIHL) is a leading cause of occupational and recreational injury and disease[3]. There is evidence that occupational noise exposure is also associated with other health effects, such as hypertension and cardiovascular diseases, digestive disorders, behavioral disorders.

关键词： occupational cardiovascular diseases

Tandem catalysis for enhanced CO oxidation over the Bi-Au-SiO_(2)interface

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Nuclear Science and Techniques 2023年第7期34卷 198-205页

作者： Huan Zhang Lei Xie Zhao-Feng Liang Chao-Qin Huang Hong-Bing Wang Jin-Ping Hu Zheng Jiang Fei Song Instrumentation and service Center for Physical Sciences Westlake UniversityHangzhou 310024China Shanghai Synchrotron radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China

Bimetallic catalysts typically exploit unique synergetic effects between two metal species to achieve their catalytic *** the mechanism of CO oxidation using hybrid heterogeneous catalysts is important for effective catalyst design and environmental ***,we report a Bi-Au/SiO_(2)tandem bimetallic catalyst for the oxidation of CO over the Au/SiO_(2)surface,which was monitored using near-ambient-pressure X-ray photoelectron *** Au-decorated SiO_(2)catalyst exhibited scarce activity in the CO oxidation reaction;however,the introduction of Bi to the Au/SiO_(2)system promoted the catalytic *** mechanism is thought to involve the dissociation O_(2)molecules in the presence of Bi,which results in spillover of the O species to adjacent Au atoms,thereby forming Au^(δ+).Further CO adsorption,followed by thermal treatment,facilitated the oxidation of CO at the Au-Bi interface,resulting in a reversible reversion to the neutral Au valence *** work provides insight into the mechanism of CO oxidation on tandem surfaces and will facilitate the rational design of other Au-based catalysts.

关键词： APXPS CO oxidation Au-Bi interface Tandem catalysis In situ

Deposition and characterization of TiZrV-Pd thin films by dc magnetron sputtering

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Chinese Physics C 2015年第12期39卷 95-99页

作者：王洁张波徐延辉尉伟范乐裴香涛洪远志王勇 National Synchrotron radiation Laboratory University of Science and Technology of China

TiZrV film is mainly applied in the ultra-high vacuum pipes of storage rings. Thin fihn coatings of palladium, which are added onto the TiZrV film to increase the service life of nonevaporable getters and enhance H2 pumping speed, were deposited on the inner face of stainless steel pipes by dc magnetron sputtering using argon gas as the sputtering gas. The TiZrV-Pd film properties were investigated by atomic force microscope （AFM）, scanning electron microscope （SEM）, X-ray photoelectron spectroscopy （XPS） and X-Ray Diffraction （XRD）. The grain size of TiZrV and Pd films were about 0.42 1.3 nm and 8.5-18.25 nm respectively. It was found that the roughness of TiZrV films is small, about 2 4 nm, but for Pd film it is large, about 17 19 nm. The PP At. % of Pd in TiZrV/Pd films varied from 86.84 to 87.56 according to the XPS test results.

关键词： TiZrV-Pd nonevaporable getters film coating dc magnetron sputtering

Research on deposition rate of TiZrV/Pd film by DC magnetron sputtering method

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Nuclear Science and Techniques 2017年第4期28卷 44-50页

作者： Jie Wang Bo Zhang Yan-Hui Xu Yong Wang National Synchrotron radiation Laboratory University of Science and Technology of China Hefei 230029 China

An accelerator storage ring needs clean ultrahigh vacuum.A TiZrV non-evaporable getter(NEG) film deposited on interior walls of the chamber can realize distributed pumping,effective vacuum improvement and reduced longitudinal pressure *** accumulation of pollutants such as N_2 and O_2 will decrease the adsorption ability of the NEG,leading to a reduction of NEG ***,an NEG thin film coated with a layer of Pd,which has high diffusion rate and absorption ability for H_2,can extend the service life of NEG and improve the pumping rate of H_2 as *** this paper,with argon as discharge gas,a magnetron sputtering method is adopted to prepare TiZrV-Pd films in a long straight *** SEM measurement,deposition rates of TiZrV-Pd films are analyzed under different deposition parameters,such as magnetic field strength,gas flow rate,discharge current,discharge voltage and working *** comparing the experimental results with the simulation results based on Sigmund's theory,the Pd deposition rate C can be estimated by the sputtered depth.

关键词： TiZrV-Pd Deposition rates Magnetron sputtering method Non-evaporable getter

Surface Oxidation and Subsurface Microstructure Evolution of Alloy 690TT Induced by Partial Slip Fretting Corrosion in High-Temperature Pure Water

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Acta Metallurgica Sinica(English Letters) 2021年第4期34卷 543-554页

作者： Long Xin Yongming Han Ligong Ling Yonghao Lu Tetsuo Shoji National Center for Materials service Safety University of Science and Technology BeijingBeijing100083China Nuclear and radiation Safety Center Beijing102401China Frontier Research Initiative New Industry Creation Hatchery CenterTohoku University6-6-10Aramaki AobaAoba-kuSendai980-8579Japan

The surface oxidation and subsurface microstructure evolution of Alloy 690 TT can occur during partial slip fretting corrosion in high-temperature pure *** characterization methods such as laser scanning confocal microscopy,scanning electron microscopy,electron probe micro-analyzer,and transmission electron microscopy were used to reveal the related *** results showed that Cr_(2)O_(3) oxides together with a small number of spinel oxides were formed in sticking region since a small quantity of high-temperature water could pass through the gaps between the asperities to oxidize the *** distribution of oxides in microslip region consisted of(Ni,Fe)Cr_(2)O_(4),because Ni^(2+)and Fe^(2+) ions could react with Cr_(2)O_(3) to generate a small amount of non-stoichiometric spinel *** oxides around micropitting in microslip region consisted of double-layer *** outermost layer contained(Fe,Cr)-rich oxides due to the effect of fretting leading to mechanical mixing between Cr_(2)O_(3) and(Ni,Fe)(Fe,Cr)_(2)O_(4).The inner layer consisted of(Fe,Ni)-rich oxides owing to the consumption of Cr_(2)O_(3) by the reaction with Ni^(2+)and Fe^(2+) *** reciprocating motion of oxide particles in microslip region resulted in the stress-strain supporting the recrystallization for the formation and development of a tribologically transformed structure in subsurface and plowing effect by fretting in surface.

关键词： Fretting corrosion Oxidation Partial slip Alloy 690TT Microstructure High-temperature water

Effects of alloying elements Mn,Mo,Ti,Si,P and C on the incubation period of void swelling in austenitic stainless steels

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Tungsten 2021年第1期3卷 3-19页

作者： Toshimasa Yoshiie Qiu Xu Institute for Integrated radiation and Nuclear Science Kyoto UniversityOsaka 590‑0494Japan

Void swelling,which induces the degradation of the original properties of nuclear materials under high-energy particleirradiation,is an important *** incubation period,a transient stage before the steady void growth,determines the duration of service of nuclear *** experimental studies have been performed on void observations by transmission electron microscopy(TEM),which,however,has a resolution limit for the size of defect *** annihilation lifetime spectroscopy(PALS)enables the detection of small vacancy clusters,single vacancies,dislocations and *** use of these two methods provides complementary information toward detecting defect information in the incubation ***,defect structures during the incubation period in austenitic stainless steels,by means of PALS and TEM are *** role of alloying elements into determining the period is ***,the existing problems and research directions in this field are presented.

关键词： Austenitic stainless steels Void swelling Incubation period Neutron irradiation Positron annihilation lifetime spectroscopy

Is There a Specific Profile of COVID-19 Risk Perception among People with Cancer?A Cross-Sectional Study

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Psycho-Oncologie 2023年第4期17卷 245-256页

作者： Renaud Mabire-Yon Arnaud Siméone Thibaud Marmorat Anne-Sophie Petit Mathilde Perray Costanza Puppo Charlotte Bauquier Claire Della Vecchia HervéPicard Marie Préau Unit 1296《radiation:Defense HealthEnvironment》INSERMUniversity Lyon 2Bron69676France LPS UR849-Aix-Marseille Université Marseille13284France service de recherche clinique Hôpital Fondation Adolphe de RothschildParis75019France

Aims:This study aimed to determine if people with cancer(PWC)exhibit a unique COVID-19 risk perception profile and identify psychosocial factors characterizing PWC who do not conform to the majority risk perception ***:A cross-sectional online self-questionnaire study was conducted in France from April 25 to May 07,2020,with a sample(n=748)comprising PWC,individuals not currently receiving cancer treatment,and those without a history of *** profiles of COVID-19 risk perception(PCRP)were ***:A multivariate multinomial logistic regression was performed to assess the association between cancer status and PCRP *** of PWC across different profiles were ***:Four profiles emerged,ranging from Low-Risk to High-Risk *** were more likely to belong to the High-Risk Perceivers profile(aOR:3.02;p<0.001).PWC not conforming to this profile had a higher perceived socioeconomic level(PSL)(p<0.05).The majority of PWC demonstrated a specific COVID-19 risk perception profile,mainly influenced by medical knowledge linking cancer to increased COVID-19 *** was a key determinant in shaping risk perception among ***:Interventions targeting COVID-19 risk perception modification should consider these factors,with particular emphasis on addressing concerns related to SARS-CoV-2 infection.

关键词： Cancer COVID-19 risk perception socioeconomic level psychosocial factors

Operando measurement of lattice deformation profiles of synchrotron radiation monochromator

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Nuclear Science and Techniques 2024年第7期35卷 8-19页

作者： Yue Zhang Zhong-Liang Li Shang-Yu Si Lian Xue Hong-Xin Luo Xiao-Wei Zhang Jun Hu Shanghai Synchrotron radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai201204China ShanghaiTech University Shanghai201210China University of the Chinese Academy of Sciences Beijing100049China Beijing Synchrotron radiation Facility Institute of High Energy PhysicsChinese Academy of ScienceBeijing100049China

This study presents a new method for characterizing the thermal lattice deformation of a monochromator with high precision under service conditions and first reports the operando measurements of nanoscale thermal lattice deformation on a double-crystal monochromator at different incident *** nanoscale thermal lattice deformation of the monochromator first crystal was obtained by analyzing the intensity of the distorted DuMond *** diagrams of the 333 diffraction index,sensitive to lattice deformation,were obtained directly using a 2D detector and an analyzer crystal orthogonal to the *** increasing incident power and power density,the maximum height of the lattice deformation increased from 3.2 to 18.5 nm,and the deformation coefficient of the maximum height increased from 1.1 to 3.2 nm/*** maximum relative standard deviation was 4.2%,and the maximum standard deviation was 0.1 *** on the measured thermal deformations,the flux saturation phenomenon and critical point for the linear operation of the monochromator were predicted with increasing incident *** study provides a simple solution to the problem of the lower precision of synchrotron radiation monochromator characterizations compared to simulations.

关键词： Synchrotron radiation Monochromator Lattice deformation X-ray dynamic diffraction