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Effects of Different Culture Conditions and Growth States on the Structure and Hemostatic Properties of Coscinodiscus sp.

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Journal of Ocean University of China 2024年第4期23卷 1121-1134页

作者： HE Zheng LI Qinfeng LIU Jinfeng HUI Guangyan FENG Chao CHENG Xiaojie CHEN Xiguang College of Marine Life Science Sanya Oceanographic InstitutionOcean University of ChinaQingdao 266003China Laboratory for Marine Drugs and Bioproducts Qingdao Marine Science and Technology CenterQingdao 266237China Department of Stomatology Qingdao Women and Children’s HospitalQingdao 266034China Department of Stomatology Qingdao Special Servicemen Recuperation Center of PLA NavyQingdao 266071China

As a renewable marine inorganic material,Coscinodiscus *** significant potential in the field of rapid ***,the low yield of Coscinodiscus *** limits the *** this study,two new culture modes were adopted to increase the production of Coscinodiscus sp.,the effect of changes in culture conditions and growth status on the hemostatic activity of diatoms was *** prevent Coscinodiscus *** sinking in culture,the suspension culture mode was realized by adding0.5%*** semi-continuous high nutrient concentration culture mode increased the cell density of Coscinodiscus *** 11000cells mL^(-1)and shorten the culture cycle to 5 *** terms of coagulation activity,the addition of frustules reduced the in vitro coagulation time by half and the activation time of coagulation by 70%.The hemolysis rate and cytotoxicity of frustules harvested in the two culture modes did not change *** results showed that suspension culture mode and high nutrient concentration culture mode only changed the growth state of Coscinodiscus sp.,while the hemostatic performance remained stable.

关键词： diatom culture Coscinodiscus sp frustule hemostatic material hemorrhage control

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Application value of machine learning models in predicting intraoperative hypothermia in laparoscopic surgery for polytrauma patients

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World Journal of Clinical Cases 2024年第24期12卷 5513-5522页

作者： Kun Zhu Zi-Xuan Zhang Miao Zhang The Second Department of Anesthesia Tianjin HospitalTianjin 300211China Department of War Rescue Training Qingdao Special Servicemen Recuperation Center of PLA NavyQingdao 266001Shandong ProvinceChina Department of Internal Medicine Qingdao Fushan Elderly ApartmentsQingdao 266001Shandong ProvinceChina

BACKGROUND Hypothermia during laparoscopic surgery in patients with multiple trauma is a significant concern owing to its potential *** learning models offer a promising approach to predict the occurrence of intraoperative *** To investigate the value of machine learning model to predict hypothermia during laparoscopic surgery in patients with multiple *** This retrospective study enrolled 220 patients who were admitted with multiple injuries between June 2018 and December *** these,154 patients were allocated to a training set and the remaining 66 were allocated to a validation set in a 7:3 *** the training set,53 cases experienced intraoperative hypothermia and 101 did *** regression analysis was used to construct a predictive model of intraoperative hypothermia in patients with polytrauma undergoing laparoscopic *** area under the curve(AUC),sensitivity,and specificity were *** Comparison of the hypothermia and non-hypothermia groups found significant differences in sex,age,baseline temperature,intraoperative temperature,duration of anesthesia,duration of surgery,intraoperative fluid infusion,crystalloid infusion,colloid infusion,and pneumoperitoneum volume(P0.05).The results of the logistic regression analysis showed that age,baseline temperature,intraoperative temperature,duration of anesthesia,and duration of surgery were independent influencing factors for intraoperative hypothermia during laparoscopic surgery(P0.05).The predictive model had AUCs of 0.850 and 0.829 for the training and validation sets,*** Machine learning effectively predicted intraoperative hypothermia in polytrauma patients undergoing laparoscopic surgery,which improved sur

关键词： Polytrauma Laparoscopic surgery Hypothermia Related factor Risk prediction

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Effects of Water Weight-Loss Walking Training on Lower Limb Motor Function and Gait in Stroke Patients

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Health 2022年第8期14卷 921-930页

作者： Jingbin Dou Mengxuan Jiang qingdao special servicemen recuperation center of pla navy Qingdao China

Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. However, the rehabilitation effect of water weight-loss training in stroke patients is currently unclear. Objective: To analyze the effect of water weight loss walking training in stroke patients. Methods: A total of 180 stroke patients admitted to our hospital from January 2019 to December 2021 were selected and randomly divided into two groups. The control group received routine walking training, and the research group performed weight loss walking training in water on this basis. The lower limb motor function, muscle tone grade, daily living ability, gait and balance ability were compared between the two groups before and after treatment. Results: Compared with the control group, the FMA-LE score (Fugl-Meyer motor assessment of Lower Extremity), MBI score (Modified Barthel Index) and BBS score (berg balance scale) of the study group were higher after treatment, and the muscle tone was lower (P Conclusion: Water weight loss walking training can enhance patients’ muscle tension, correct patients’ abnormal gait, improve patients’ balance and walking ability, and contribute to patients’ motor function recovery and self-care ability improvement.

关键词： Stroke Water Weight Loss Walking Training Balance Ability Three-Dimensional Gait Analysis Lower Limb Motor Function

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