检索结果-南通市图书馆

Nano research 2023年第8期16卷 11296-11302页

作者： Zhao Han Bo Wang Jie You qiancui Zhang Yichi Zhang Tian Miao Ningning Zhang Dongdong Lin Zuimin Jiang Renxu Jia Jincheng Zhang Hui Guo Huiyong Hu Liming Wang Key Laboratory of Analog Integrated Circuits and Systems Ministry of EducationSchool of MicroelectronicsXidian UniversityXi’an 710071China qian xuesen collaborative research center of astrochemistry and space life sciences Department of Microelectronic Science and EngineeringNingbo UniversityNingbo 315211China Department of Physics Fudan UniversityShanghai 200433China

The contradiction between the high number of visually handicapped people and the scarcity of guide dogs has stimulated the demand for electronic guide dogs(EGDs).Here,we demonstrate an EGD by leveraging piezoresistors on a MoS_(2)/Ge heterostructure for simultaneous pressure-sensing and optical-sensing functions.The device has excellent gating capability and exhibits large positive and negative photoresponses under visible(532 nm,182 A/W)and infrared(1550 nm,37 A/W)illumination.These characteristics allow the device to efficiently classify different obstacles at all times of day using pressure and light signals.The device reaches nearly 100%accuracy after 48 training sessions when used to classify frequent scenes.The device adopts passive and active detection modes during the day and night,respectively,which improves the battery life of the EGD.This work provides a significant reference for the future design of EGDs,which may help a greater number of visually impaired people by reducing the cost of such devices.

关键词： electronic guide dogs dual-band photodetection pressure and light synergy work round the clock

Simulating tactile and visual multisensory behaviour in humans based on an MoS_(2) field effect transistor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano research 2023年第5期16卷 7405-7412页

作者： Jie You Liming Wang Yichi Zhang Dongdong Lin Bo Wang Zhao Han Ningning Zhang Tian Miao Maliang Liu Zuimin Jiang Hui Guo Yimeng Zhang Jincheng Zhang Huiyong Hu Wide Bandgap Semiconductor Technology Disciplines State Key Laboratory School of Microelectronics Xidian UniversityXi’an 710071China qian xuesen collaborative research center of astrochemistry and space life sciences Department of Microelectronic Science and EngineeringNingbo UniversityNingbo 315211China Department of Physics Fudan UniversityShanghai 200433China

A visual and tactile multisensory integrated system is essential for human walking due to the demand for real-time interactions between perception and action.Here,a piezoresistor and MoS_(2)field effect transistor are combined to construct an artificial integration nervous system to simulate perception and synaptic plasticity.The key characteristics of synaptic plasticity are successfully demonstrated by individual pressure signals,individual optical signals,the synergy of optical and pressure signals,which are based on the electron trapping–detrapping mechanism at the MoS_(2)/SiO_(2)interface.We demonstrate that perception under synergy is stronger than perception under optical or pressure signal alone,which is similar to a biological system.Moreover,various distinguishable motion scenarios(combination of the following conditions:external lighting environment of day or night,flat or rough road,movement state of walking or running)are simulated and verified by adjusting the amplitude and frequency of the optical and pressure signals.

关键词： visual tactile multisensory system motion scenarios

Diverse glasses revealed from Chang'E-5 lunar regolith

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2023年第12期10卷 150-163页

作者： Rui Zhao Laiquan Shen Dongdong Xiao Chao Chang Yao Huang Jihao Yu Huaping Zhang Ming Liu Shaofan Zhao Wei Yao Zhen Lu Baoan Sun Haiyang Bai Zhigang Zou Mengfei Yang Weihua Wang Institute of Physics Chinese Academy of Sciences center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences qian xuesen Laboratory of space Technology China Academy of Space Technology Songshan Lake Materials Laboratory 5. College of Engineering and Applied sciences Nanjing University China Academy of space Technology

Lunar glasses with different origins act as snapshots of their formation processes,providing a rich archive of the Moon’s formation and evolution.Here,we reveal diverse glasses from Chang’E-5(CE-5) lunar regolith,and clarify their physical origins of liquid quenching,vapor deposition and irradiation damage respectively.The series of quenched glasses,including rotation-featured particles,vesicular agglutinates and adhered melts,record multiple-scale impact events.Abundant micro-impact products,like micron-to nano-scale glass droplets or craters,highlight that the regolith is heavily reworked by frequent micrometeorite bombardment.Distinct from Apollo samples,the indigenous ultra-elongated glass fibers drawn from viscous melts and the widespread ultra-thin deposited amorphous rims without nanophase iron particles both indicate a relatively gentle impact environment at the CE-5 landing site.The clarification of multitype CE-5 glasses also provides a catalogue of diverse lunar glasses,meaning that more of the Moon’ s mysteries,recorded in glasses,could be deciphered in future.

关键词： lunar glasses glass fibers amorphous rims micrometeorite impacts gentle impact environment

Trimetaphosphate-induced chiral selection between amino acid and nucleoside using ^(15)N-^(31)P coupling NMR

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2022年第2期33卷 821-824页

作者： Jianxi Ying Ruiwen Ding Yumeng Zhang Bowen Han Yeting Guo Ning Wang Dandan Guo Yile Wu Junwei Huang Yan Liu Feng Ni Shaohua Huang Yufen Zhao Institute of Drug Discovery Technology Ningbo UniversityNingbo 315211China qian xuesen collaborative research center of astrochemistry and space life sciences Ningbo UniversityNingbo 315211China Department of Chemical Biology College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education) Department of ChemistryTsinghua UniversityBeijing 100084China

life on Earth uses a common set of L-amino acids(L-aa)to construct proteins and D-nucleosides(D-Nu)to form nucleic acids,which serve as the carrier of genetic information.Herein,we reveal the in-trinsic mechanism of chiral selection of L-aa and D-Nu from the perspective of chemical origin of life.This work employed^(15)N-labeled L-aa and performed one-pot synthesis of nucleotide amidate of amino acid(N-aa-NMP)using equal amounts of L-^(15)N-aa and D-^(14)N-aa with D-/L-Nu in the aqueous solution of trimetaphosphate,generating L-^(15)N-aa-NMP and D-^(14)N-aa-NMP,respectively.The ^(31)P-NMR data indicated that L-aa was preferentially selected during the formation of N-aa-NMP in the presence of D-Nu.Surpris-ingly,D-aa was preferred over L-aa in the presence of L-Nu.Further analysis revealed that L-^(15)N-aa-D-NMP vs.D-^(14)N-aa-L-NMP and D-^(14)N-aa-D-NMP vs.L-^(15)N-aa-L-NMP were mirror isomers of each other,respec-tively.These data suggest that there could be a set of chiral systems opposite to that on Earth,which infers there might be a world of life that is a mirror image of the Earth.

关键词： Chiral selection Amino acids Nucleosides Prebiotic chemistry Origin of life

In situ resource utilization of lunar soil for highly efficient extraterrestrial fuel and oxygen supply

在线全文

学校读者我要写书评

暂无评论

National Science Review 2023年第2期10卷 224-231页

作者： Yuan Zhong Jingxiang Low Qing Zhu Yawen Jiang Xiwen Yu Xinyu Wang Fei Zhang Weiwei Shang Ran Long Yingfang Yao Wei Yao Jun Jiang Yi Luo Weihua Wang Jinlong Yang Zhigang Zou Yujie Xiong Hefei National research center for Physical sciences at the Microscale School of Chemistry and Materials Science National Synchrotron Radiation Laboratory School of Information Science and TechnologyUniversity of Science and Technology of China Eco-Materials and Renewable Energy research center (ERERC) Jiangsu Key Laboratory for Nano Technology National Laboratory of Solid State MicrostructuresSchool of PhysicsCollaborative Innovation Center of Advanced MicrostructuresCollege of Engineering and Applied SciencesNanjing University qian xuesen Laboratory of space Technology China Academy of Space Technology

Building up a lunar settlement is the ultimate aim of lunar exploitation.Yet, limited fuel and oxygen supplies restrict human survival on the Moon.Herein,we demonstrate the in situ resource utilization of lunar soil for extraterrestrial fuel and oxygen production,which may power up our solely natural satellite and supply respiratory gas.Specifically,the lunar soil is loaded with Cu species and employed for electro catalytic CO2conversion,demonstrating significant production of methane.In addition,the selected component in lunar soil(i.e.MgSiO3) loaded with Cu can reach a CH4F aradaic efficiency of 72.05% with a CH4production rate of 0.8 mL/min at 600 mA/cm2.Simultaneously,an O2production rate of 2.3 mL/min can be achieved.Furthermore,we demonstrate that our developed process starting from catalyst preparation to electrocatalytic CO2conversion is so accessible that it can be operated in an unmmaned manner via a robotic system.Such a highly efficient extraterrestrial fuel and oxygen production system is expected to push forward the development of mankind’s civilization toward an extraterrestrial settlement.

关键词： Chang’E-5 lunar soil fuel production CO2 conversion extraterrestrial settlement in situ resource utilization

Chinese Medicine Meets Conventional Medicine in Targeting COVID-19 Pathophysiology,Complications and Comorbidities

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2022年第7期28卷 627-635页

作者： WANG Shan-shan ZENG Xian WANG Ya-li Zhuoma Dongzhi ZHAO Yu-fen CHEN Yu-zong qian xuesen collaborative research center of astrochemistry and space life sciences Institute of Drug Discovery TechnologyNingbo UniversityNingboZhejiang Province 315211China Department of Biological Medicines&Shanghai Engineering research center of Immunotherapeutics Fudan University School of PharmacyShanghai 201203China Bioinformatics and Drug Design Group Department of PharmacyNational University of Singapore117543Singapore Medical College Tibet UniversityLhasa 850011China Department of Chemical Biology College of Chemistry and Chemical Engineeringand The Key Laboratory for Chemical Biology of Fujian ProvinceXiamen UniversityXiamenFujian Province 361005China Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education) Department of ChemistryTsinghua UniversityBeijing 102206China

Objective: To investigate how the National Health Commission of China(NHCC)-recommended Chinese medicines(CMs) modulate the major maladjustments of coronavirus disease 2019(COVID-19),particularly the clinically observed complications and comorbidities. Methods: By focusing on the potent targets in common with the conventional medicines, we investigated the mechanisms of 11 NHCC-recommended CMs in the modulation of the major COVID-19 pathophysiology(hyperinflammations, viral replication), complications(pain, headache) and comorbidities(hypertension, obesity, diabetes). The constituent herbs of these CMs and their chemical ingredients were from the Traditional Chinese Medicine Information Database. The experimentally-determined targets and the activity values of the chemical ingredients of these CMs were from the Natural Product Activity and Species Source Database. The approved and clinical trial drugs against these targets were searched from the Therapeutic Target Database and DrugBank Database. Pathways of the targets was obtained from Kyoto Encyclopedia of Genes and Genomes and additional literature search. Results: Overall,9 CMs modulated 6 targets discovered by the COVID-19 target discovery studies, 8 and 11 CMs modulated 8and 6 targets of the approved or clinical trial drugs for the treatment of the major COVID-19 complications and comorbidities, respectively. Conclusion: The coordinated actions of each NHCC-recommended CM against a few targets of the major COVID-19 pathophysiology, complications and comorbidities, partly have common mechanisms with the conventional medicines.

关键词： COVID-19 Chinese medicine target therapeutic mechanism pathophysiology comorbidity

Theoretical investigation on the elusive biomimetic iron(Ⅲ)-iodosylarene chemistry: An unusual hydride transfer triggers the Ritter reaction

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2021年第12期32卷 3857-3861页

作者： Lanping Gao Xiaolu Chen Dongru Sun Hua Zhao Yufen Zhao Wonwoo Nam Yong Wang Institute of Drug Discovery Technology Ningbo UniversityNingbo 315211China qian xuesen collaborative research center of astrochemistry and space life sciences Ningbo UniversityNingbo 3152UChina Department of Chemistry and Nano Science Ewha Womans UniversitySeoul 03760Korea

Introduction of iodosylarnes into biomimetic nonheme chemistry has made great achievement on identification of the subtle metal-oxygen reaction intermediates. However, after more than three decades of experimental and theoretical efforts the nature of the metal-iodosylarene adducts and the related dichotomous one-oxidant/multiple-oxident controversy have remained a matter of speculation. Herein, we report a theoretical study of the structure-activity relationship of the noted iron(Ⅲ)-iodsylarene complex,FeⅢ(Ph IO)(OTf)3(1), in oxygenation of cyclohexene. The calculated results revealed that 1 behaves like a chameleon by adapting its roles as a 2 e-oxidant or an oxygen donor, as a response to the regioselective attack of the C–H bond and the C=C bond. The oxidative C–H bond activation by 1 was found, for the first time, to proceed via a novel hydride transfer process to form a cyclohexene carbonium intermediate,such non-rebound step triggers the Ritter reaction to uptake an acetonitrile molecule to form the amide product, or proceeds with the rebound of the hydroxyl group return to the solvent cage to form the hydroxylated product. While in the C=C bond activation, 1 is a normal oxygen donor and shows two-state reactivity to present the epoxide product via a direct oxygen atom transfer mechanism. These mechanistic findings fit and explain the famous Valentine’s experiments and enrich the non-rebound scenario in bioinorganic chemistry.

关键词： Reaction mechanism DFT calculations Metal-iodosylbenzene Ritter reaction Olefin oxidation

Deep Domain Decomposition Methods:Helmholtz Equation

在线全文

学校读者我要写书评

暂无评论

Advances in Applied Mathematics and Mechanics 2023年第1期15卷 118-138页

作者： Wuyang Li Ziming Wang Tao Cui Yingxiang Xu Xueshuang Xiang School of Mathematics and Statistics Jilin National Applied Mathematics Center at NENUNortheast Normal UniversityChangchunJilin 130024China NCMIS LSECAcademy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China qian xuesen Laboratory of space Technology China Academy of Space TechnologyBeijing 100094China School of Mathematical sciences University of Chinese Academy of SciencesBeijing 100049China

This paper proposes a deep-learning-based Robin-Robin domain decomposition method(DeepDDM)for Helmholtz equations.We first present the plane wave activation-based neural network(PWNN),which is more efficient for solving Helmholtz equations with constant coefficients and wavenumber k than finite difference methods(FDM).On this basis,we use PWNN to discretize the subproblems divided by domain decomposition methods(DDM),which is the main idea of DeepDDM.This paper will investigate the number of iterations of using DeepDDM for continuous and discontinuous Helmholtz equations.The results demonstrate that:DeepDDM exhibits behaviors consistent with conventional robust FDM-based domain decomposition method(FDM-DDM)under the same Robin parameters,i.e.,the number of iterations by DeepDDM is almost the same as that of FDM-DDM.By choosing suitable Robin parameters on different subdomains,the convergence rate is almost constant with the rise of wavenumber in both continuous and discontinuous cases.The performance of DeepDDM on Helmholtz equations may provide new insights for improving the PDE solver by deep learning.

关键词： Helmholtz equation deep learning domain decomposition method plane wave method

Prebiotic Chemistry in Aqueous Environment:A Review of Peptide Synthesis and Its Relationship with Genetic Code

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2021年第8期39卷 2264-2272页

作者： Jianxi Ying Ruiwen Ding Yan Liu Yufen Zhao Institute of Drug Discovery Technology Ningbo UniversityNo.818 Fenghua RoadNingboZhejiang 315211China qian xuesen collaborative research center of astrochemistry and space life sciences Ningbo UniversityNo.818 Fenghua RoadNingboZhejiang 315211China College of Chemistry and Chemical Engineering Xiamen UniversityNo.422Siming South RoadXiamenFujian 361005China

Prebiotic peptide synthesis and the origin of the genetic code are central issues concerning the origin of life.The question of how they are possibly correlated on the primordial Earth remains perplexing,although numerous experiments have been carried out to explain the prebiotic chemistry of peptide synthesis and the genetic code origin.The purpose of this article is to review the chemical reactions occurred during the synthesis of peptides and the origin of the genetic code in the early Earth aqueous environment.Meanwhile,we attempt to review their relationship as well.At last,from our perspective,the chiral properties of biomolecules should be taken into account in the prebiotic chemical scenarios,which may contribute to some breakthroughs in the further research of this field.

关键词： Amino acids Peptides Molecular evolution Prebiotic chemistry Genetic code origin

Recent Progress of Microgravity Science research in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

空间科学学报 2022年第4期42卷 772-785页

作者： ZHAO Jianfu DU Wangfang KANG Qi LAN Ding LI Kai LI Weibin LIU Y C LUO Xinghong MIAO Jianyin WANG Qinggong WANG Shuangfeng ZHANG Tao ZHANG Xingwang ZHANG Yonghai ZHENG Huiqiong CAS Key Laboratory of Microgravity Institute of MechanicsChinese Academy of SciencesBeijing 100190 School of Engineering Science University of Chinese Academy of SciencesBeijing 100049 center for Combustion Energy Tsinghua UniversityBeijing 100084 Institute of Metal research Chinese Academy of SciencesShenyang 110016 Institute of spacecraft System Engineering China Academy of Space TechnologyBeijing 100094 qian xuesen Laboratory of space Technology China Academy of Space TechnologyBeijing 100094 Shanghai Institute of Technical Physics Chinese Academy of SciencesShanghai 200083 Institute of Semiconductors Chinese Academy of SciencesBeijing 100083 School of Chemical Engineering and Technology Xi’an Jiaotong UniversityXi’an 710049 center for Excellence in Molecular Plant sciences Chinese Academy of SciencesShanghai 200032

Microgravity science is an important branch of space science.Its major objective is to study the laws of materials movement in microgravity,as well as to reveal the influence of gravity on the movement of materials in different gravity environments.Application researches relevant to these basic studies are also important contents of microgravity science.The advanced subjects,to some extent,reflect the ability of human beings to understand nature and the R&D level in this field in various countries.In this paper,the recent progress and the latest achievements of microgravity science and application researches in China aboard space platforms such as the Core Capsule Tianhe of the China space Station(CSS)and satellites,as well as utilizing ground-based short-term microgravity facilities such as the Drop Tower Beijing and TUFF,are summarized,which cover the following sub-disciplines:microgravity fluid physics,microgravity combustion science,space materials science,space fundamental physics,space bio-technology,and relevant space technology applications.

关键词： Microgravity science China space Station(CSS) Ground-based short-term microgravity platforms Microgravity fluid physics Microgravity combustion science space materials science space fundamental physics space bio-technology