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A Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults—China,2017–2021

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China CDC weekly 2024年第23期6卷 537-541,I0001-I0007页

作者： Yidan Qiu Saisai Ji Chen Chen Jinhui Zhou Jun Wang Bing Wu Yuan Wei Fangyu Li Xulin Zheng Lanjing Xu Zheng Zhang Feng Zhao Guangdi Chen John SJi Yuebin Lyu Shilu Tong Xiaoming Shi Department of Big Data in health Science School of Public HealthZhejiang UniversityHangzhou CityZhejiang ProvinceChina China CDC Key Laboratory of Environment and Population health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina Center for Global health School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of Epidemiology and Biostatistics School of Public HealthJilin UniversityChangchun CityJilin ProvinceChina School of public health China Medical UniversityShenyang CityLiaoning ProvinceChina institute of Environmental health School of Public Healthand Bioelectromagnetics LaboratorySchool of MedicineZhejiang UniversityHangzhou CityZhejiang ProvinceChina Environmental Research Center Duke Kunshan UniversityKunshan CityJiangsu ProvinceChina Nicholas School of the Environment Duke UniversityDurhamNCUSA School of public health Institute of Environment and Population HealthAnhui Medical UniversityHefei CityAnhui ProvinceChina School of public health and Social Work Queensland University of TechnologyBrisbaneAustralia

What is already known about this topic?Antimony(Sb)has been identified as a new neurotoxicant that impacts neurological functions in animal ***,its effects on the human population remain *** is added by this report?The study reveals that there is an association between exposure to Sb and a higher incidence of cognitive impairment in older *** dose-response curve demonstrates that the risk of cognitive impairment consistently increased with higher levels of Sb exposure without a discernible *** are the implications for public health practice?Reducing exposure to Sb may have a beneficial effect in delaying or preventing the onset of cognitive *** intervention has the potential to significantly decrease the disease burden associated with cognitive impairment,ultimately contributing to social development.

关键词： Antimony development. exposure

Construction of Prediction Model of Foodborne Disease Outbreaks and Its Trend Prediction—Guizhou Province,China,2023-2025

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China CDC weekly 2024年第18期6卷 408-408,I0009,409-412,I0010-I0015页

作者： Li Zhang Sufang Xiong Shu Zhu Jigui Tian Qingyuan Chen Xiaobo Luo Hua Guo institute of public health Surveillance and Evaluation Guizhou Center for Disease Control and PreventionGuiyang CityGuizhou ProvinceChina School of public health Guizhou Medical University.Guiyang CityGuizhou ProvinceChina

Objective:Foodborne diseases pose a significant public health concern *** study aims to analyze the correlation between disease prevalence and climatic conditions,forecast the pattern of foodborne disease outbreaks,and offer insights for effective prevention and control strategies and optimizing health resource allocation policies in Guizhou ***:This study utilized theχ^(2) test and four comprehensive prediction models to analyze foodborne disease outbreaks recorded in the Guizhou Foodborne Disease Outbreak system between 2012 and *** best-performing model was chosen to forecast the trend of foodborne disease outbreaks in Guizhou Province,***:Significant variations were observed in the incidence of foodborne disease outbreaks in Guizhou Province concerning various meteorological factors(all P≤0.05).Among all models,the SARIMA-ARIMAX combined model demonstrated the most accurate predictive performance(RMSE:Prophet model=67.645,SARIMA model=3.953,ARIMAX model=26.544,SARIMA-ARIMAX model=26.196;MAPE:Prophet model=42.357%,SARIMA model=37.740%,ARIMAX model=15.289%,SARIMA-ARIMAX model=13.961%).Conclusion:The analysis indicates that foodborne disease outbreaks in Guizhou Province demonstrate distinct seasonal *** is recommended to concentrate prevention efforts during peak *** SARIMA-ARIMAX hybrid model enhances the precision of monthly forecasts for foodborne disease outbreaks,offering valuable insights for future prevention and control strategies.

关键词： Guizhou prevention offering

Higher intakes of lysine,threonine and valine are inversely associated with non-alcoholic fatty liver disease risk:a community-based case-control study in the Chinese elderly

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Food Science and Human Wellness 2024年第1期13卷 191-197页

作者： Xueqi Li Wenjun Ma Ting Yang Chong Wang Wei Zhang Hui Li Ting Zhao Xiaofei Guo institute of Nutrition&health School of Public HealthQingdao UniversityQingdao 260071China Affiliated Hospital of Qingdao University Qingdao 260071China

The associations of individual amino acid with non-alcoholic fatty liver disease(NAFLD)risk remained *** present study aimed to investigate the associations between the two in the Chinese ***:A community-based health check-up program was conducted in Qingdao,*** was diagnosed by ultrasonography accompanied by epidemiological *** dietary intakes of amino acids were investigated with 3-day,24-h dietary records and calculated by Nutrition Calculator *** cubic spline model was used to evaluate a nonlinear relationship between amino acid intake and NAFLD ***:400 NAFLD subjects were identified,and 400 participants were randomly selected as controls and matched by gender and age(±3 years)Dose-response analysis showed that 1000 mg increment of aromatic amino acids(AAAs)was associated with reduced 16%risk of *** increments of 750 mg/d threonine,950 mg/d valine,or 1700 mg/d lysine were associated with a 20%reduction in the NAFLD risk(all P for linearity<0.05).Conclusion:The present study demonstrated that the dietary increases in milk,eggs and deep-sea fish,which are rich in the amino acids,might contribute to protecting against NAFLD in the elderly.

关键词： Amino acid Non-alcoholic fatty liver disease Senior citizen Dose-response analysis

Association of Thallium Exposure with Decreased Renal Function among Chinese Adults—China,2017-2018

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China CDC weekly 2024年第34期6卷 867-871,I0007-I0010页

作者： Zheng Zhang Miao Zhang Yingli Qu Feng Zhao Saisai Ji Zheng Li Bing Wu Chunxian Lyu Haocan Song Qi Sun Yawei Li Xu Zhang Xulin Zheng Yidan Qiu Zihan Lu Hui Fu Lanjing Xu Wenli Zhang Yufei Luo Fangyu Li Jiayi Cai Yuanduo Zhu Ying Zhu Zhaojin Cao Yuebin Lyu Xiaoming Shi China CDC Key Laboratory of Environment and Population health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina Center for Global health School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of Big Data in health Science School of Public HealthZhejiang UniversityHangzhou CityZhejiang ProvinceChina Department of Occupational health and Environment health School of Public HealthAnhui Medical UniversityHefei CityAnhui ProvinceChina School of public health China Medical UniversityShenyang CityLiaoning ProvinceChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases(NITFID) National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?Thallium(Tl)is significantly more toxic than heavy metals such as lead,cadmium,and ***,previous studies examining the relationship between Tl exposure and the risk of chr... 详细信息

关键词： Renal kidney mercury

Prevalence of Cannabis Use around the World:A Systematic Review and Meta-Analysis,2000-2024

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China CDC weekly 2024年第25期6卷 597-604,I0013,I0014页

作者： Qianning Wang Zhen Qin Xing Xing He Zhu Zhongwei Jia National institute of health Data Science Center for Drug Abuse Prevention and ControlPeking UniversityBeijingChina School of public health Peking UniversityBeijingChina

This study aims to perform a systematic review and meta-analysis on the global prevalence of cannabis use to inform drug prevention strategies,policy-making,and resource *** study initially screened 177,843 studies published between January 1,2000,and January 15,2024,using peer-reviewed databases including Web of Science,PubMed,Scopus,Embase,and Cochrane ***,595 studies were identified for data extraction,and 39 of these were selected as country-representative *** among the selected studies was assessed using the chi-squared test and I2 statistic,while sensitivity analysis was conducted to evaluate the robustness of the *** prevalence of cannabis use varied between 0.42%and 43.90%across 33 European countries,1.40%to 38.12%across 15 North and South American countries,0.30%to 19.10%across 16 Asian countries,and 1.30%to 48.70%across 18 Oceania and African *** pooled prevalence of cannabis use was 12.0%[95%confidence interval(CI):10.0,14.3]in countries where cannabis is legalized,compared to 5.4%(95%CI:4.3,6.9)in non-legalized *** findings indicate that the prevalence of cannabis use has disproportionately increased in most countries with the implementation of medical or recreational cannabis legalization policies and relevant geographic *** efforts are needed to monitor newly cannabis-legalized countries and prevent initial use.

关键词： prevention legal initially

health Risk Assessment of Employees Exposed to Chlorination By-products of Recreational Water in Large Amusement Parks in Shanghai

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Biomedical and Environmental Sciences 2024年第8期37卷 865-875页

作者： Weizhao Cao Yiming Zheng Wenxuan Zhao Lisha Shi Yunhui Zhang Lijun Zhang Jian Chen Key Lab of health Technology Assessment National Health Commission of the People’s Republic of China(Fudan University)Shanghai 200032China Key Laboratory of public health Safety Ministry of EducationSchool of Public HealthFudan UniversityShanghai 200032China Division of public health Service and Safety Assessment Shanghai Municipal Center for Disease Control and PreventionShanghai 200336China Shanghai institute of Preventive Medicine Shanghai 200336China

Objective Chlorination is often used to disinfect recreational water in large amusement parks;however,the health hazards of chlorination disinfection by-products(DBPs)to occupational populations are *** study aimed to assess the exposure status of chlorinated DBPs in recreational water and the health risks to employees of large amusement *** Exposure parameters of employees of three large amusement parks in Shanghai were investigated using a *** typical chlorinated DBPs in recreational water and spray samples were quantified by gas chromatography,and the health risks to amusement park employees exposed to chlorinated DBPs were evaluated according to the WHO's risk assessment *** Trichloroacetic acid,dibromochloromethane,bromodichloromethane,and dichloroacetic acid were detected predominantly in recreational *** carcinogenic and non-carcinogenic risks of the five DBPs did not exceed the risk *** addition,the carcinogenic and non-carcinogenic risks of mixed exposure to DBPs were within the acceptable risk *** Typical DBPs were widely detected in recreational water collected from three large amusement parks in Shanghai;however,the health risks of DBPs and their mixtures were within acceptable limits.

关键词： Risk assessment Water Environmental health Occupational exposure Chlorinated disinfection by-product

health benefits from the rapid reduction in ambient exposure to air pollutants after China's clean air actions:progress in efficacy and geographic equality

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National Science Review 2024年第2期11卷 103-113页

作者： Tao Xue Ruohan Wang Meng Wang Yanying Wang Dan Tong Xia Meng Conghong Huang Siqi Ai Fangzhou Li Jingyuan Cao Mingkun Tong Xueqiu Ni Hengyi Liu Jianyu Deng Hong Lu Wei Wan Jicheng Gong Shiqiu Zhang Tong Zhu institute of Reproductive and Child health National Health Commission Key Laboratory of Reproductive Health/Department of Epidemiology and Biostatistics Ministry of Education Key Laboratory of Epidemiology of Major Diseases(PKU) School of Public Health Peking University Health Science Centre State Environmental Protection Key Laboratory of Atmospheric Exposure and Health Risk Management and Center for Environment and Health Peking University Advanced institute of Information Technology Peking University Department of Epidemiology and Environmental health School of Public Health and Health ProfessionsUniversity at Buffalo State Key Joint Laboratory of Environment Simulation and Pollution Control College of Environmental Sciences and EngineeringPeking University Department of Earth System Science Tsinghua University School of public health Key Laboratory of Public Health Safety of the Ministry of Education and Key Laboratory of Health Technology Assessment of the Ministry of HealthFudan University College of Land Management Nanjing Agricultural University National&Local Joint Engineering Research Center for Rural Land Resources Use and Consolidation Clean Air Asia

Clean air actions （CAAs） in China have been linked to considerable benefits in public ***,whether the beneficial effects of CAAs are equally distributed geographically is *** high-resolution maps of the distributions of major air pollutants (fine particulate matter[PM2.5]and ozone[O3]) and population,we aimed to track spatiotemporal changes in health impacts from,and geographic inequality embedded in,the reduced exposures to PM2.5and O3from 2013 to *** used a method established by the Global Burden of Diseases *** analyzing the changes in loss of life expectancy（LLE） attributable to PM2.5and O3,we calculated the gain of life expectancy （GLE） to quantify the health benefits of the air-quality ***,we assessed the geographic inequality embedded in the GLE using the Gini index （GI）.Based on risk assessments of PM2.5and O3,during the first stage of CAAs（2013 to 2017）,the mean GLE was 1.87 *** of the sum of the GLE was disproportionally distributed in about one quarter of the population exposed （GI 0.44）.During the second stage of CAAs（2017 to 2020）,the mean GLE increased to 3.94 months and geographic inequality decreased （GI 0.18）.According to our assessments,CAAs were enhanced,from the first to second stages,in terms of not only preventing premature mortality but also ameliorating health *** enhancements were related to increased sensitivity to the health effects of air pollution and synergic control of PM2.5and *** findings will contribute to optimizing future CAAs.

关键词： clean air action public health inequality fine particulate matter ozone

Epidemiological Characteristics of Fracture Among Children Aged 6-17 Years-China,2019-2021

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China CDC weekly 2024年第32期6卷 799-803,I0001页

作者： Lu Cui Qian Gan Juan Xu Peipei Xu Titi Yang Wei Cao Hongliang Wang Haoyan Guo Ruihe Luo Jianfen Zhang Hui Pan Wenhua Zhao Zhenyu Yang Yuxiang Yan Qian Zhang Department of Epidemiology and Biostatistics School of Public HealthCapital Medical UniversityBeijingChina National institute for Nutrition and health Chinese Center for Disease Control and PreventionBeijingChina Key Laboratory of public Nutrition and health National Health Commission of the People’s Republic of ChinaBeijingChina

Summary What is already known about this topic?Fractures are a common and serious injury among *** many studies have utilized clinical data,there is a lack of large-scale community-based research in *** is added by this report?This cross-sectional study provides national and regionally representative data on the prevalence of fractures among Chinese children aged 6–17 years(6.93%),with higher rates observed in males than in females(8.13%vs.5.71%)and in rural areas compared to urban areas(7.22%vs.6.62%).The most common site of fracture was the upper limbs(4.24%,accounting for 63.0%of fractures).What are the implications for public health practice?The need to enhance awareness of fracture prevention is critical,particularly for children in rural areas and males in middle *** recommend that local authorities increase investments in educational programs and child safety ***,promoting balanced diets for children,training in proper exercise techniques,and reinforcing participation in outdoor sports are essential.

关键词： prevention utilized children

Epidermolysis Bullosa Pruriginosa in Two Siblings:A Case Report

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International Journal of Dermatology and Venereology 2024年第1期7卷 52-54页

作者： Jongjin Suwanthaweemeesuk Chatip Phunmanee Sasathorn Singthong Oraya Kwangsukstid Chavalit Supsrisunjai institute of Dermatology Department of Medical ServicesMinistry of Public HealthBangkok 10400Thailand

Introduction:Epidermolysis bullosa pruriginosa(EBP)is a rare clinical subtype of inherited dystrophic epidermolysis bullosa(DEB)caused by type VII collagen *** onset of EBP is variable and may present in late *** clinical features of EBP include prurigo-like papules,plaques,nodules,or linear configuration on the lower ***,we reported two sisters with *** presentation:We identified two Thai sisters with mild to moderate form of EBP,which resulted from a shared glycine substitution(Gly2287Val)in COL7A1 identified by genomic ***:The histology and molecular findings of both cases supported a diagnosis of dystrophic EBP,however,the clinical manifestations differ between both ***:Molecular testing is the key for the diagnosis of EBP due to nonspecific clinical manifestation and histologic findings,however,there is no clear genotype-phenotype correlation in EBP.

关键词： COL7A1 dystrophic epidermolysis bullosa epidermolysis bullosa pruriginosa Gly2287Val