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Effects of a school-based karate intervention on academic achievement,psychosocial functioning,and physical fitness:A multi-country cluster randomized controlled trial

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Journal of Sport and Health Science 2024年第1期13卷 90-98页

作者： Tania Pinto-Escalona Erica Gobbi Pedro L.Valenzuela Simon J.Bennett Pierluigi Aschieri Manuel Martin-Loeches Antonio Paoli Oscar Martinez-de-Quel Faculty of Education Complutense University of MadridMadrid 28040Spain Department of Biomolecular Sciences University of Urbino“Carlo Bo”Urbino 61029Italy Department of Systems Biology University of AlcaláMadrid 28805Spain Research Institute for Sport and Exercise Sciences Faculty of ScienceLiverpool John Moores UniversityLiverpoolL33AFUK Italian Judo WrestlingKarate and Martial Arts FederationRome 00122Italy psychobiology&Methods for the Behavioural Sciences Department Complutense University of MadridMadrid 28040Spain Department of Biomedical Sciences University of PaduaPadua 35122Italy

Purpose:To examine the effects of a school-based karate intervention on academic achievement,psychosocial functioning,and physical fitness in children aged 7-8 ***:Twenty schools in 5 different European countries(2 second-grade classrooms per school)participated in a cluster randomized controlled trial(Sport at School trial).Participants were assigned to either a control group,which continued with their habitual physical education lessons,or to an intervention group,which replaced these lessons with a 1-year karate intervention(Karate Mind and Movement program).A total of 721 children(344 girls and 377 boys,7.4±0.5 years old,mean±SD)completed the study,of which 333 and 388 were assigned to the control group and intervention group,*** included academic performance(average grade),psychosocial functioning(Strengths and Difficulties Questionnaire for parents),and different markers of physical fitness(cardiorespiratory fitness,balance,and flexibility).Results:The intervention provided small but significant benefits compared to the control group for academic achievement(d=0.16;p=0.003),conduct problems(d=-0.28;p=0.003),cardiorespiratory fitness(d=0.36;p0.05).Conclusion:A 1-year school-based karate intervention was effective in improving academic achievement,conduct problems,and physical fitness in primary school *** results support the inclusion of karate during physical education lessons.

关键词： Academic performance Cardiorespiratory fitness Conduct problems Karate Physical fitness

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Is it possible to run after positive affective experiences instead of health benefits without tackling social inequalities?

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Journal of Sport and Health Science 2024年第6期13卷 756-758页

作者： Raphael H.O.Araujo Andre O.Werneck Gilmar M.de Jesus Danilo R.P.Silva graduation program in Health Sciences Londrina State UniversityLondrina 86057-970Brazil School of Public Health The University of QueenslandBrisbane QLD 4006Australia Center for Epidemiological Research in Nutrition and Health Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil Department of Psychological Medicine Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon SE58AFUK Public Health Post-Graduate program State University of Feira de SantanaFeira de Santana 44036-900Brazil Department of Physical Education Federal University of SergipeSao Cristovao 490100-000Brazil

We recently read the opinion piece titled“Why people should run after positive affective experiences instead of health benefits”,which was carried out by Maltagliati et al.^(1)and published in the Journal of Sport and Health *** article started an important discussion about a physical activity(PA)promotion approach that encourages the use of affective experience to PA *** we agree with the authors’point of view and believe that its message can generate an important insight for PA promotion,the authors presented a scenario where behavior change seems to be exclusively dependent on the *** the existence of other barriers to an active lifestyle(e.g.,social inequalities)could enhance the authors’suggested approach because many people live in conditions that reduce their opportunities to engage in affective experiences related to PA;furthermore,affective experiences can vary depending on individual context.

关键词： promotion inequalities furthermore

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Promoting integrative medicine by computerization of traditional Chinese medicine for scientific research and clinical practice: The SuiteTCM Project

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Journal of Integrative Medicine 2013年第2期11卷 135-139页

作者： Arthur de Sá Ferreira Laboratory of Computational Simulation and Modeling in Rehabilitation Post-graduation Program of Rehabilitation Science Augusto Motta University Center

BACKGROUND： Chinese and contemporary Western medical practices evolved on different cultures and historical contexts and, therefore, their medical knowledge represents this cultural divergence. Computerization of traditional Chinese medicine （TCM） is being used to promote the integrative medicine to manage, process and integrate the knowledge related to TCM anatomy, physiology, semiology, pathophysiology, and therapy. METHODS： We proposed the development of the SuiteTCM software, a collection of integrated computational models mainly derived from epidemiology and statistical sciences for computerization of Chinese medicine scientific research and clinical practice in all levels of prevention. The software includes components for data management （DataTCM）, simulation of cases （SimTCM）, analyses and validation of datasets （SciTCM）, clinical examination and pattern differentiation （DiagTCM, TongueTCM, and PulseTCM）, intervention selection （AcuTCM, HerbsTCM, and DietTCM）, management of medical records （ProntTCM）, epidemiologic investigation of sampled data （ResearchTCM）, and medical education, training, and assessment （StudentTCM）. DISCUSSION： The SuiteTCM project is expected to contribute to the ongoing development of integrative medicine and the applicability of TCM in worldwide scientific research and health care. The SuiteTCM 1.0 runs on Windows XP or later and is freely available for download as an executable application.

关键词： traditional Chinese medicine evidence-based practice computer-assisted decision making

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Nuclear reprogramming: the zygotic transcription program is established through an“erase-and-rebuild” strategy

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Cell Research 2007年第2期17卷 117-134页

作者： Feng Sun~(1,*) Haiyan Fang~(2,*) Ruizhen Li~(2,*) Tianlong Gao~1 Junke Zheng~2 Xuejin Chen~2 Wenqin Ying~2 Hui Z Sheng~2 ~1program for graduation Studies,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China ~2Center for Developmental Biology,Xinhua Hospital,School of Medicine,Shanghai Jiao Tong University,1665 Long Jiang Road,Shanghai 200092,China program for graduation Studies Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai China Center for Developmental Biology Xinhua Hospital School of Medicine Shanghai Jiao Tong University Shanghai China

Oocytes display a maternal-specific gene expression profile,which is switched to a zygotic profile when a haploidset of chromatin is passed on to the fertilized egg that develops into an *** mechanism underlying this tran-scription reprogramming is currently *** we demonstrate that by the time when transcription is shut downin germinal vesicle oocytes,a range of general transcription factors and transcriptional regulators are dissociated fromthe *** global dissociation of chromatin factors(CFs)disrupts physical contacts between the chromatin andCFs and leads to erasure of the maternal transcription program at the functional *** transcription factors andregulators remain separated from chromatin for a prolonged period,and become re-associated with chromatin shortlyafter pronuclear *** is followed temporally by the re-establishment of nuclear functions such as DNA rep-lication and *** propose that the maternal transcription program is erased during oogenesis to generatea relatively naive chromatin and the zygotic transcription program is rebuilt de novo after *** process istermed as the"erase-and-rebuild"process,which is used to reset the transcription program,and most likely other nuclearprocesses as well,from a maternal one to that of the *** further show in the accompanying paper(Gao T,et al.,Cell Res 2007:17:135-150.)that the same strategy is also employed to reprogram transcriptional profiles in somatic cellnuclear transfer and parthenogenesis,suggesting that this model is universally applicable to all forms of transcriptionalreprogramming during early *** of CFs from chromatin also offers an explanation for thephenomenon of transcription silence during the maternal to zygotic transition.

关键词： nuclear reprogramming transcription transcription silence chromatin factors embryogenesis fertilization oogenesis

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Coupled dynamic model of state estimation for hypersonic glide vehicle

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Journal of Systems Engineering and Electronics 2018年第6期29卷 1284-1292页

作者： ZHANG Kai XIONG Jiajun FU Tingting Department of graduation Air Force Early Warning Academy Early Warning Intelligence Department Air Force Early Warning Academy

Aiming at handling complicated maneuvers or other unpredicted emergencies for hypersonic glide vehicle tracking,three coupled dynamic models of state estimation based on the priori information between guidance variables and aerodynamics are presented. Firstly, the aerodynamic acceleration acting on the target is analyzed to reveal the essence of the target’s *** three coupled structures for modeling aerodynamic parameters are developed by different ideas: the spiral model with a harmonic oscillator, the bank model with trigonometric functions of the bank angle and the guide model with the changing rule of guidance variables. Meanwhile, the comparison discussion is concluded to show the novelty and advantage of these ***, a performance assessment in different simulation cases is presented and detailed analysis is revealed. The results show that the proposed models perform excellent properties. Moreover, the guide model produces the best tracking performance and the bank model shows the second; however, the spiral model does not outperform the maneuvering reentry vehicle(MaRV) model markedly.

关键词： hypersonic glide vehicle state estimation dynamic model aerodynamic parameter guidance variable

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Nutritional evaluation in cirrhosis: Emphasis on the phase angle

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World Journal of Hepatology 2016年第29期8卷 1205-1211页

作者： Sabrina Alves Fernandes Angelo Alves de Mattos Cristiane Valle Tovo Claudio Augusto Marroni Postgraduate program at Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) Post graduation program in Bioscience and Rehabilitation and the Post graduation program in Rehabilitation and Inclusion Methodist University-IPA

Protein-calorie malnutrition (PCM) is a common condition in cirrhotic patients, leading to a worse prognosis, complications, poor quality of life and lower survival rates. Among ways of assessing nutritional status, there are anthropometric methods such as the evaluation of the triceps skinfold, the arm circumference, the arm muscle circumference and the body mass index, and non-anthropometric methods such as the subjective global assessment, the handgrip strength of non-dominant hand, and the bioelectrical impedance analysis (BIA). PCM is frequently under-diagnosed in clinical settings in patients with cirrhosis due to the limitations of nutritional evaluation methods in this population. BIA is a useful method, but cannot be indicated in patients with abnormal body composition. In these situations, the phase angle (PA) has been used, and can become an important tool in assessing nutritional status in any situation. The PA is superior to anthropometric methods and might be considered as a nutritional indicator in cirrhosis. The early characterization of the nutritional status in patients with cirrhosis means an early nutritional intervention, with a positive impact on patients’ overall prognosis. Among the usually accepted methods for nutritional diagnosis, the PA provides information in a quick and objective manner.

关键词： Malnutrition Bioelectrical impedance Phase angle Sarcopenia Nutrition

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Nuclear reprogramming: the strategy used in normal development is also used in somatic cell nuclear transfer and parthenogenesis

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Cell Research 2007年第2期17卷 135-150页

作者： Tianlong Gao~(1,*) Junke Zheng~(2,*) Fengying Xing~(2,*) Haiyan Fang~2 Feng Sun~1 Ayong Yan~2 Xun Gong~2 Hui Ding~3 Fan Tang~2 Hui Z Sheng~2 ~1program for graduation Studies,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China ~2Center for Developmental Biology,Xinhua Hospital,Shanghai Jiao Tong University,School of Medicine,1665 Kong Jiang Road,Shanghai 200092,China ~3School of Animal Science and Technology,Yangzhou University,Yangzhou 225009,China program for graduation Studies Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai China Center for Developmental Biology Xinhua Hospital Shanghai Jiao Tong University School of Medicine Shanghai China School of Animal Science and Technology Yangzhou University Yangzhou China

Somatic cell nuclear transfer(SCNT)and parthenogenesis are alternative forms of reproduction and development,building new life cycles on differentiated somatic cell nuclei and duplicated maternal chromatin,*** thepreceding paper(Sun F,et al.,Cell Res 2007;17:117-134.),we showed that an"erase-and-rebuild"strategy is used innormal development to transform the maternal gene expression profile to a zygotic ***,we investigate if the samestrategy also applies to SCNT and *** relationship between chromatin and chromatin factors(CFs)during SCNT and parthenogenesis was examined using immunochemical and GFP-fusion protein *** fromthese studies indicated that soon after nuclear transfer,a majority of CFs dissociated from somatic nuclei and were re-distributed to the cytoplasm of the *** erasure process in oogenesis is recaptured during the initial phase in *** CFs entered pseudo-pronuclei shortly after their *** parthenogenesis,all parthenogenotes underwentnormal oogenesis,and thus had removed most CFs from chromosomes before the initiation of *** CFswere subsequently re-associated with female pronuclei in time and sequence similar to that in fertilized *** these data,we conclude that the"erase-and-rebuild"process observed in normal development also occurs in SCNTand in parthenogenesis,albeit in altered *** process is responsible for transcription reprogramming in ***"erase"process in SCNT is compressed and the efficiency is compromised,which likely contribute tothe developmental defects often observed in nuclear transfer(nt)***,results from this study indicatedthat the cytoplasm of an egg contains most,if not all,essential components for assembling the zygotic program and canassemble them onto appropriate diploid chromatin of distinct origins.

关键词： nuclear reprogramming SCNT parthenogenesis chromatin factors chromatin embryogenesis

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Activation of the corticotropin-releasing factor receptor from the basolateral or central amygdala modulates nociception in guinea pigs

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Advances in Bioscience and Biotechnology 2013年第6期4卷 20-27页

作者： Alberto Ferreira Donatti Christie Ramos Andrade Leite-Panissi psychobiology graduation program School of PhilosophyScience and Literature of Ribeirao Preto of the University of Sao PauloRibeirao PretoBrazil Department of Morphology Physiology and Basic PathologyRibeirao Preto Dentistry SchoolUniversity of Sao PauloRibeirao PretoBrazil

Corticotropin-releasing factor (CRF) is a peptide that is released from the hypothalamus into widespread areas of the brain. Evidence has suggested that CRF is involved as a neuromodulator outside of the hypothalamic-pituitary-adrenal axis, playing an important role in fear, anxiety, depression and pain modulation. Our previous report demonstrated that CRF receptor activation in basolateral (BLA) or central nuclei of the amygdala (CeA) produces innate fear in guinea pigs. Inhibition of these receptors via administration of α-helical CRF9-41 (a nonspecific antagonist) into the CeA or BLA decreased innate fear behavior [1]. Additionally, there is strong evidence that emotional behavior and nociception can be modulated simultaneously. The present study was conducted to investigate the involvement of the CRF receptors of the BLA or CeA in nociception in guinea pigs. Guinea pigs were treated with CRF and α-helical CRF>9-41> in three different doses or injected with α-helical CRF9-41 preceded by CRF into the BLA or CeA, and they were evaluated using the hot plate test. Our findings indicated that activation of CRF receptors in the BLA and in the CeA promoted antinociception, and this effect was reversed by preadministration of α-helical CRF9-41 in the same area. The treatment with α-helical CRF>9-41> per se into the BLA and CeA did not alter nociception. Thus, nociception modulation occurs in a phasic manner, whereas defensive behavior can occur tonically because the α-helical CRF9-41 did not cause any modification on the index of analgesia in the hot plate test but did reduce innate fear behavior [1].

关键词： Amygdala α-Helical CRF_(9-41) Nociception Acute Pain Hot Plate Test

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Natural Attenuation and Biostimulation of Biodiesel Contaminated Soils from Southern Brazil with Different Particle Sizes

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Journal of Environmental Science and Engineering(B) 2012年第2期1卷 155-162页

作者： Liliane R.R. Meneghetti Antonio Thome Femando Schnaid Pedro D.M. Prietto Gabriel Cavelhao graduation program in Civil Engineering Federal University of Rio Grande do Sul Porto Alegre 90035-190 Brazil graduation program in Engineering University of Passo Fundo Passo Fundo 99052-900 Brazil

Biodiesel bioremediation in soils may occur by natural attenuation or by engineered techniques, such as biostimulation and bioaugmentation. The present study evaluated the degradation of biodiesel in two soils with different particle size characteristics by the bioremediation processes of natural attenuation and biostimulation. The experiment was carried out ex situ, with the factors temperature, moisture content, and pH being controlled for the experimental period of 110 days. The study aimed at evaluating the biodegradation of a clayey soil （A） and a sandy soil （B）, both contaminated with pure biodiesel, by using the analytical methods of respirometry and gas chromatography. Biostimulation treatments using nitrogen, phosphorus, and potassium solutions （NPK） promoted higher microbiological activity in both soils. At the end of the experiment, it was observed that biostimulation was more efficient when compared to natural attenuation, showing higher biodiesel degradation for both soils A （59.76%） and B （90.41%）.

关键词： Biodegradation COz evolution gas chromatography.

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HPV18 Utilizes Two Alternative Branch Sites for E6*I Splicing to Produce E7 Protein

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Virologica Sinica 2019年第2期34卷 211-221页

作者： Ayslan Castro Brant Vladimir Majerciak Miguel Angelo Martins Moreira Zhi-Ming Zheng Tumor Virus RNA Biology Section RNA Biology Laboratory Center for Cancer Research National Cancer Institute NIH Frederick MD 21702 USA Genetics Post-graduation program Rio de Janeiro Federal University Rio de Janeiro Brazil Genetics program Nacional Cancer Institute INCA Rio de Janeiro 20231-050 Brazil

Human papillomavirus 18(HPV18) E6 and E7 oncogenes are transcribed as a single bicistronic E6 E7 pre-mRNA. The E6 ORF region in the bicistronic E6 E7 pre-mRNA contains an intron. Splicing of this intron disrupts the E6 ORF integrity and produces a spliced E6*I RNA for efficient E7 translation. Here we report that the E6 intron has two overlapped branch point sequences(BPS) upstream of its 30 splice site, with an identical heptamer AACUAAC, for E6*I splicing. One heptamer has a branch site adenosine(underlined) at nt 384 and the other at nt 388. E6*I splicing efficiency correlates to the expression level of E6 and E7 proteins and depends on the selection of which branch site. In general, E6*I splicing prefers the 30 ss-proximal branch site at nt 388 over the distal branch site at nt 384. Inactivation of the nt 388 branch site was found to activate a cryptic acceptor site at nt 636 for aberrant RNA splicing. Together, these data suggest that HPV18 modulates its production ratio of E6 and E7 proteins by alternative selection of the two mapped branch sites for the E6*I splicing, which could be beneficial in its productive or oncogenic infection according to the host cell environment.

关键词： Human papillomavirus 18 (HPV18) HPV splicing Branch point E6,E7,E6 intron HPV oncogenes

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