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Effect of Pentoxifyiline on necrosis rate and hemorrheology of free flap

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外科研究与新技术 2011年第4期 272-273页

作者：冷冰 Dept plast surg Hosp China Med Univ

Objective To investigate effect of Pentoxifylline on free flap. Methods Forty Wistar rats were chosen as experimental models and free flaps were harvested from the back of rats,which as pect ratio was 3: 1. Then they ... 详细信息

关键词： rate Effect of Pentoxifyiline on necrosis rate and hemorrheology of free flap free

Distribution and pheotype changes of macrophage in infantile hemangioma

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外科研究与新技术 2011年第4期 271-272页

作者：陈岩青 Dept plast surg Nanfang HospSouthern Med Univ

Objective To observe distribution and phenotypc changes of macrophage in infantile hemangioma. Methods Forty - three infantile hemangioma samples were harvested from resection operation,Distribution and phenolype chan... 详细信息

关键词： Distribution and pheotype changes of macrophage in infantile hemangioma

The design and transposition principles of expanded flap for treatment of cheek skin-soft tissue defect

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China Medical Abstracts 2007年第2期16卷 152-153页

作者：胡守舵 plast surg hosp Chin Acad Sci Beijing 100041

Objective To explore an ideal method for repairing the skin-soft tissue defects according to the different anatomical units of cheek, and find reasonable design principles to transfer the expanded flaps. Methods Acoording to the location of the defect, we placed 1-3 appropriate expanders nearby, when the flap expanded enough we adopted advanced skin flaps,

关键词：扩张覆盖技术整形手术颊面皮肤皮肤软化手术

Effect of a combination of local flap and sequential compression- distraction osteogenesis in the reconstruction of post-traumatic tibial bone and soft tissue defects

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Chinese Medical Journal 2013年第15期126卷 2846-2851页

作者： HU Xiao-hua HUANG Lei CHEN Zhong DU Wei-li WANG Cheng SHEN Yu-ming Beijing Jishuitan hosp Dept Burns & Plast Surg Beijing 100035 Peoples R China Beijing Jishuitan hosp Dept Orthoped Surg Beijing 100035 Peoples R China

Background Treatment of extensive post-traumatic composite bone and soft tissue defects remains a complicated therapeutic problem and a challenge for surgeons. We investigated the application of local flaps and Ilizarov osteogenesis in the reestablishment of severe combined defects of tibial bone and soft tissue. Methods Sixteen patients with bone and soft tissue defects were included. The mean age of the patients was 31.5 years. The average time from injury to initial surgery was 14.4 weeks. The average soft tissue and bone defect sizes were 92.9 cm2 and 8.7 cm, respectively. Local flaps were created to reconstruct the soft tissue defects. The Ilizarov external fixator or the Orthofix Limb Reconstruction System was used to reconstruct bony defects using delayed distraction osteogenesis. Results Two myocutaneous flaps and 14 reverse island flaps were applied. All transferred flaps survived. Fifteen patients healed with equal leg length, and one healed with a residual leg-length discrepancy of 1.5 cm. One patient with an Ilizarov external fixator developed ankle joint stiffening and a pin-track infection that was successfully treated with oral antibiotics. No patient developed pin loosening. All patients walked without assistance. Fifteen patients returned to their work, and one lost her job. The results were evaluated using the Paley bone and functional assessment scores. The bone assessment results were excellent in 14 and good in two patients. Functional assessment scores were excellent in 13, good in two, and fair in one patient. Conclusion The combination of local flaps and sequential distraction osteogenesis can be used for successful reconstruction of defects of incorporated bone and soft tissue.

关键词： bone defect soft tissue loss treatment local flap compression-distraction osteogenesis

Rejuvenation of the forehead/temple by limited incision

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外科研究与新技术 2005年第3期 211-212页

作者：郑行跃 plast surg hosp Chin Acad Med SciBeijing 100041

To utilize multiplane,subcutaneous and subperiosteal,dissection through small incisions in scalp to rejuvenate aging signs of forehead/*** Forehead:We make four small incisions in scalp,widely separate tissues between subperiosteum skin and frontal muscle to form galea frontal muscle-periosteum flap,the flap is tighten and sutured with the galea at the posterior border of the *** method avoid to excise ***:there are two small incisions in the scalp of temple at each *** temple fascia and orbicularis oculi muscle as while is dissected from deep temporal fascia and skin respectively,then tightened and sutured with the superficail part of deep temporal fascia,excising scalp is not *** Twenty patients have received this treatment,the effects are *** Multiplane dissection through small incisions can remove wrinkles of skin,correct the prolapse of eyebrow and avoid the complications of coronary *** approach brings more rapid recorery of patients,it is safe and affective.7 refs,4 figs.

关键词： incision

Applied distally based peroneus brevis muscle flaps for coverage of the soft tissue defects over the lower one-third of the leg, ankle and foot

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外科研究与新技术 2003年第2期 128-129页

作者：邓国三 Dept plast surg Guangdong Provin Peop hosp Guangzhou 510080

Objective To investigate a simple, valuable new method for coverage of the soft tissue defect over the lower one-third of the leg, ankle and the foot. Methods The distally based peroneus brevis muscle fkps were applied for coverage of the soft tissue defects over the lower one-third of the leg,the ankle and the foot. The muscle flaps were covered with split-thickness skin grafts. Results The distally based peroneus brevis muscle flaps were applied for coverage of the soft tissue defects over the lower one-third of the leg, the ankle and the foot in 16 cases. The larges area of the soft tissue defect was 5 cm × 7 cm. The smallest was 3 cm × 4 cm. Primary healing occured in 14 cases undergoing muscle flap construction, second-stage healing occured in 2 cases, no total flap necrosis occured in any cases. Conclusion ThisChina Medical Abstracts(surgery) technigue is a simple and complication are lesser. The successful rates are higher. This muscle flap is suitable to the mudium or small soft tissue

关键词： of Applied distally based peroneus brevis muscle flaps for coverage of the soft tissue defects over the lower one-third of the leg ankle and foot

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World Journal of Otorhinolaryngology-Head and Neck surgery 2023年第3期9卷 262-269页

作者： Razavi, Christopher R. Wang, Tom Icahn Sch Med Mt Sinai Dept Otolaryngol Head & Neck Surg Div Facil Plast & Reconstruct Surg New York NY 10029 USA Oregon Hlth & Sci Univ Dept Otolaryngol Head & Neck Surg Div Facil Plast & Reconstruct Surg Portland OR 97201 USA

*** Thank you for your interest in World Journal of Otorhinolaryngology-Head&Neck surgery(WJOHNS).Note that submission implies that the content has not been published or submitted for publication elsewhere except as a... 详细信息

关键词： implies content surgery

Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro

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Hepatobiliary & Pancreatic Diseases International 2007年第1期6卷 72-80页

作者： Fan, Yue-Zu Fu, Jin-Ye Zhao, Ze-Ming Chen, Chun-Qiu Tongji Univ Tongji Hosp Dept Gen Surg Shanghai 200065 Peoples R China Pudong Peoples hosp Dept Surg Shanghai 201200 Peoples R China

BACKGROUND: Gallbladder carcinoma is a lethal malignant neoplasm with dismal surgical results. Unfortunately, the adjuvant therapies for gallbladder carcinoma such as chemotherapy and radiotherapy are also disappointing. We reported that norcantharidin (NCTD), a demethylated form of cantharidin, which is an active ingredient of the Chinese medicine Mylabris, was used against human gallbladder carcinoma GBC-SD cells. In the present study, we further studied the mechanism underlying the inhibitory effect of NCTD on growth of human gallbladder carcinoma GBC-SD cells in vitro. METHODS: Human gallbladder carcinoma GBC-SD cells were grown in cell culture and divided into a NCTD group and a control group. The inhibitory effect of NCTD on growth of GBC-SD cells was investigated by evaluation of proliferation, cell cycle, apoptosis and morphological changes of the cells. Cell proliferation was assessed by tetrazolium-based colorimetric assay. The induction of cell cycle arrest and apoptosis was measured by flow cytometry. The morphological changes of the cells were observed by light- and electron-microscopy. To elucidate the anticancer mechanism of NCTD, expression of the proliferation-related gene proteins PCNA, Ki-67, cyclin-D-1 and p27 and the apoptosis-related gene proteins Bcl-2, Bax and Survivin were determined by the streptavidin-biotin complex method and RT-PCR. RESULTS: NCTD inhibited the proliferation of GBCSD cells in a dose- and time-dependent manner, with an IC50 of 56.18 mu g/ml at 48 hours. The flow cytometric profiles revealed that NCTD (at the IC50 for 48 hours) significantly increased the proportion of cells in G(2)/M phase and significantly decreased the proportion of cells in S phase, with a significantly increased rate of cell apoptosis. After treatment with the 48-hour IC50 dose of NCTD, cell shrinkage, vacuolar cytoplasm, membrane budding, karyorrhexis, karyolysis, chromosome condensation and chromatin aggregation in some GBCSD cells were observed by l

关键词： norcantharidin gallbladder neoplasm growth proliferation cell cycle apoptosis proliferation- and apoptosis-related genes

A ＂silicone suture＂ technique aied to scalp reduction for the treatment of scarring alopecia

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China Medical Abstracts 2007年第2期16卷 149-150页

作者：王继萍 Hair Trahsplant Center Plast Surg HospChin Acad Med SciBeijing 100041

Objective To evaluate a ＂silicone suture＂ technique for enhancing the effect of scalp *** Under the local anesthesia,when an incision was made in the midine of the lesion,the dissection was carried out underlying the subgales on both sides of the lesion,as far as the width of the lesion.A 3mm silicone suture in diameter was placed in the galea beyond the lesion.

关键词：硅酮结构疤痕头皮变形手术手术治疗