检索结果-南通市图书馆

Pharmacodynamic evaluation for antiplasmodial activity of Holarrhena antidysentrica(Kutaja) and Azadirachta indica(Neemb) in Plasmodium berghei infected mice model

引用

Asian Pacific Journal of Tropical Medicine 2013年第7期6卷 520-524页

作者： Jadhav Priyanka Lal Hingorani Kshirsagar Nilima University Department of Infectious Diseases and University Department of Interpathy Research and Technology.Maharashtra University of Health Sciences.Mumbai India pharmanza herbals pvt.ltd. MumbaiIndia Office of National Chair(Clinical Pharmacology).Indian Council of Medical Research(ICMR).Government of India Dean ESI-PGIMSR MGM HospitalGovt.of India.MumbaiIndia

Objective:To investigate in-vivo anti-plasmodial activity of aqueous extracts of plants selected based on the symptomology mentioned in ***:The aqueous extracts of Holarrhena antidysentrica(***)(Kutaja) and Azadirachta indica(***)(Neemb) for their antiplasmodial potential in Plasmodium berghei(***) infected mice was assessed using Peters four day suppressive *** the extracts were administered at 2 dose levels,full dose(1 000 mg/d) and minimized dose(200 mg/d).10~6 *** infected RBCs were injected on day ’0’ and treated from day ’0’ till day ’3’ post-infection,Tail blood smears were collected, giemsa stained and *** mice were observed for survival and parasitemia was assessed till 50%of mice in control ***:It was observed that the percentage of parasitemia increased gradually in all the groups,with maximum in control group(Day 3-35,Day 9-46.98) and minimum in Chloroquine arm(Day *** 9-19.92).The percentage of parasitemia was compared using Mann-Whitney U test depicting that all test groups exhibited reduction in parasitemia as compared to control(P-value<0.002 for all groups).These groups showed similar percentage of survival as ***:The present investigation demonstrated the anti-plasmodial effects of *** and *** are two most commonly used medicinal plants in Ayurved for treatment of fever.

关键词： Holarrhena antidysentrica Azadirachta indica Plasmodium berghei Malaria Peter’s 4 day test Ayurved Parasitemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：