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Examining the Hypothesis of Common Factors Shared by Different Addictive Behaviors and Gender Effects on Propensity to Addiction Type

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Open Journal of Medical psychology 2024年第3期13卷 58-70页

作者： Masayo Uji Junko Watanabe Toshinori Kitamura Department of Clinical psychology Human Development Education Graduate School of Education Hyogo University of Teacher Education Kat Japan Academic Skill Support Center Kumamoto Health Science University Kumamoto Japan Kitamura Institute Mental Health Tokyo Tokyo Japan

Background: From the two facts reported by previous research: 1) frequent co-occurrence of more than one addictive behavior, 2) childhood adversities identified as origins of different types of addictive behaviors, it is assumed that all types of addictive behaviors, regardless of substance, behavioral, or relationship, share common factors which have not yet been proven by epidemiological research. The Shorter PROMIS Questionnaire (SPQ) was previously developed to assess 16 types of addictive behaviors. Its factor structure, however, has not been fully investigated. Confirming the factor structure will enable us to hypothesize the common factor(s) shared by all, or if not all, most types of addictive behaviors. Aims: This study aimed at 1) examining the factor structure of the SPQ, 2) confirming the reliability of the questionnaire, and 3) examining the impacts of gender and age on each addictive behavior. Methods: Data obtained from 232 Japanese adults who completed all items of the SPQ were used for the analyses. After confirming the one-factor structure model for each of the 16 subscales, the validity of the one-factor structure of the SPQ was evaluated using Confirmatory Factor Analysis (CFA), by adapting 16 subscale scores as observed variables. If its validity was not confirmed, another model which showed better compatibility to the data was explored. The reliability of the SPQ as well as that of all 16 subscales was evaluated. Also, the impacts of gender and age on each subscale score were examined. Results: The one-factor structure for each of the 16 subscales was confirmed. The compatibility of the SPQ one-factor model was not acceptable. The best fit model was a bi-factor model in which one main factor was shared by all 16 subscales, and three factors were shared by some specific addictive behaviors. Male respondents were more likely than female respondents to show high scores in Alcohol, Tobacco, Gambling, Sex, and Recreational Drugs, and low scores only

关键词： Addictive Behaviors Shorter PROMIS Questionnaire Confirmatory Factor Analysis

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Risk stratification for radioactive iodine refractoriness using molecular alterations in distant metastatic differentiated thyroid cancer

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Chinese Journal of Cancer Research 2024年第1期36卷 25-35页

作者： Zhuanzhuan Mu Xin Zhang Dongquan Liang Jugao Fang Ge Chen Wenting Guo Di Sun Yuqing Sun Zhentian Kai Lisha Huang Jun Liang Yansong Lin Department of Nuclear Medicine State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College(PUMC)HospitalChinese Academy of Medical Sciences&PUMCBeijing 100730China Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine Beijing 100730China pepperdine university graduate school of education and psychology Los Angeles 90045USA Department of Head and Neck Surgery Affiliated Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of General Surgery State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College(PUMC)HospitalChinese Academy of Medical Sciences&PUMCBeijing 100730China Central Laboratory State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College(PUMC)HospitalChinese Academy of Medical Sciences&PUMCBeijing 100730China Department of Bioinformatics Zhejiang Shaoxing Topgen Biomedical Technology Co.LtdShanghai 201321China Department of Medicine Zhejiang Shaoxing Topgen Biomedical Technology Co.LtdShanghai 201321China Department of Oncology Peking University International HospitalBeijing 102206China

Objective: Patients with radioactive iodine-refractory differentiated thyroid cancer(RAIR-DTC) are often diagnosed with delay and constrained to limited treatment options. The correlation between RAI refractoriness and the underlying genetic characteristics has not been extensively ***: Adult patients with distant metastatic DTC were enrolled and assigned to undergo next-generation sequencing of a customized 26-gene panel(Thyro Lead). Patients were classified into RAIR-DTC or non-RAIR groups to determine the differences in clinicopathological and molecular characteristics. Molecular risk stratification(MRS) was constructed based on the association between molecular alterations identified and RAI refractoriness, and the results were classified as high, intermediate or low ***: A total of 220 patients with distant metastases were included, 63.2% of whom were identified as RAIRDTC. Genetic alterations were identified in 90% of all the patients, with BRAF(59.7% vs. 17.3%), TERT promoter(43.9% vs. 7.4%), and TP53 mutations(11.5% vs. 3.7%) being more prevalent in the RAIR-DTC group than in the non-RAIR group, except for RET fusions(15.8% vs. 39.5%), which had the opposite pattern. BRAF and TERT promoter are independent predictors of RAIR-DTC, accounting for 67.6% of patients with RAIR-DTC. MRS was strongly associated with RAI refractoriness(P<0.001), with an odds ratio(OR) of high to low MRS of 7.52 [95%confidence interval(95% CI), 3.96-14.28;P<0.001] and an OR of intermediate to low MRS of 3.20(95% CI,1.01-10.14;P=0.041).Conclusions: Molecular alterations were associated with RAI refractoriness, with BRAF and TERT promoter mutations being the predominant contributors, followed by TP53 and DICER1 mutations. MRS might serve as a valuable tool for both prognosticating clinical outcomes and directing precision-based therapeutic interventions.

关键词： Differentiated thyroid cancer distant metastases genetic alterations RAI refractoriness molecular risk stratification

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Prehospital transdermal glyceryl trinitrate for ultra- acute ischaemic stroke: data from the RIGHT- 2 randomised sham- controlled ambulance trial

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Stroke & Vascular Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason Philip Appleton Lisa J Woodhouse Craig S Anderson Sandeep Ankolekar Lesley Cala Mark Dixon Timothy J England Kailash Krishnan Grant Mair Keith W Muir John Potter Christopher I Price Marc Randall Thompson G Robinson Christine Roffe Else C Sandset Jeffrey L Saver Angela Shone Aloysius Niroshan Siriwardena Joanna M Wardlaw Nikola Sprigg Philip M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied HealthResearch University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Faculty of Medicine The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute China at Peking university Health Science Center BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia Department of Neurology King's College Hospital NHS Foundation TrustLondonUK Faculty of Health and Medical Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia East Midlands Ambulance Service NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK Centre for Clinical Brain Sciences Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and psychology University of GlasgowGlasgowUK Bob Champion Research and education Building University of East AngliaNorwichUK Institute of Neuroscience Newcastle UniversityNewcastle upon TyneUK Department of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre University of LeicesterLeicesterUK Stroke Research in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK Department of Neurology Oslo University HospitalOsloNorway Research and Development Norwegian Air Ambulance FoundationOsloNorway Department of Neurology and Comprehensive Stroke Center David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Research and graduate Services University of NottinghamNottinghamUK Community and Health Research Unit University of LincolnLincolnUK

Background The effect of transdermal glyceryl trinitrate(GTN,a nitrovasodilator)on clinical outcome when administered before hospital admission in suspected stroke patients is ***,we assess the safety and efficacy of GTN in the prespecified subgroup of patients who had an ischaemic stroke within the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2(RIGHT-2).Methods RIGHT-2 was an ambulance-based multicentre sham-controlled blinded-endpoint study with patients randomised within 4hours of *** primary outcome was a shift in scores on the modified Rankin scale(mRS)at day *** outcomes included death;a global analysis(Wei-Lachin test)containing Barthel Index,EuroQol-5D,mRS,telephone interview for cognitive status-modified and Zung depression scale;and neuroimaging-determined‘brain frailty’*** were reported as n(%),mean(SD),median[IQR],adjusted common OR(acOR),mean difference or Mann-Whitney difference(MWD)with 95%*** 597 of 1149(52%)patients had a final diagnosis of ischaemic stroke;age 75(12)years,premorbid mRS>2107(18%),Glasgow Coma Scale 14(2)and time from onset to randomisation 67[45,108]***‘brain frailty’was common:median score 2[2,3](range 0–3).At day 90,GTN did not influence the primary outcome(acOR for increased disability 1.15,95%CI 0.85 to 1.54),death or global analysis(MWD 0.00,95%CI-0.10 to 0.09).In subgroup analyses,there were non-significant interactions suggesting GTN may be associated with more death and dependency in participants randomised within 1hour of symptom onset and in those with more severe *** In patients who had an ischaemic stroke,ultra-acute administration of transdermal GTN in the ambulance did not improve clinical outcomes in a population with more clinical and radiological frailty than seen in previous in-hospital *** IS ALREADY KNOWN ON THIS TOPIC⇒Transdermal glyceryl trinitrate(GTN)was associat-ed with less death and dependency in those w

关键词： Glasgow nitrate random

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Differences between DSM-5-TR and ICD-11 revisions of attention deficit/hyperactivity disorder:A commentary on implications and opportunities

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World Journal of Psychiatry 2023年第5期13卷 138-143页

作者： Rapson Gomez Wai Chen Stephen Houghton school of Science Psychologyand SportFederation UniversityMelbourne 3806Australia Curtin Medical school Curtin UniversityPerth 6102Australia graduate school of education The University of Western AustraliaPerth 6009Australia

Current ICD-11 descriptions for attention deficit hyperactivity disorder(ADHD)were recently published online,in the same year as the DSM-5-TR(text revised edition)was *** this commentary,we compare and contrast the DSM-5/DSM-5-TR and ICD-11 diagnostic criteria,summarize important differences,and underscore their clinical and research ***,three major differences emerge:(1)The number of diagnostic criteria for inattention(IA),hyperactivity(HY)and impulsivity(IM)symptoms(i.e.,DSM-5-TR has nine IA and nine HY/IM symptoms,whereas ICD-11 has 11 IA and 11 HY/IM symptoms);(2)the clarity and standardization of diagnostic thresholds(i.e.,the diagnostic thresholds for symptom count in IA and HY/IM domains are explicitly specified in DSM-5-TR,whereas in ICD-11 they are not);and(3)the partitioning of HY and IM symptoms into sub-dimensions(i.e.,difference in partitioning HY and IM symptom domains relates to the differences between the current and previous editions of DSM and ICD,and this has important research implications).Currently,no ICD-11 based ADHD rating scales exist and while this absence represents an obstacle for respective research and clinical practice,it also presents opportunities for research *** article highlights these challenges,possible remedies and novel research opportunities.

关键词： DSM dimensions specified

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Evidence in Support of Analogical Reasoning Improvements with Executive Attention Intervention in Healthy Young Adults

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Neuroscience Bulletin 2022年第12期38卷 1476-1490页

作者： Yixuan Lin Qing Li Mengke Zhang Yujie Su Xiangpeng Wang Hong Li Antao Chen Key Laboratory of Cognition and Personality of Ministry of education Faculty of PsychologySouthwest UniversityChongqing 400715China Collaborative Innovation Center for Language Ability Jiangsu Key Laboratory of Language and Cognitive NeuroscienceSchool of Linguistic Sciences and ArtsJiangsu Normal UniversityXuzhou 221116China Key Laboratory of Brain Cognition and educational Science Ministry of EducationSchool of PsychologySouth China Normal UniversityGuangzhou 510631China school of psychology Shanghai University of SportShanghai 200438China

Analogical reasoning improvement is important in educational outcome *** by recent ideas and evidence,we applied anti-saccade task training as an executive attention intervention and tested whether it could improve analogical reasoning performance.A serial-task paradigm was applied where participants performed an anti-saccade followed by an analogical reasoning task including a perception *** experimental group finished the anti-saccade task in which the ratio of anti-saccade trials to pro-saccade trials was 5:1 while the counterpart was 1:1 in the active control ***,a blank control group was established where participants merely finished the analogical reasoning ***-related electroencephalographic(EEG)data were recorded when participants were performing the executive attention and analogical reasoning *** addition,their resting state EEG was collected before and after the executive attention ***,the experimental group reacted significantly faster than the other two groups in analogical reasoning but not in *** the neural level,in the experimental group alone,the anti-saccade trials elicited a smaller N2 than pro-saccade trials and the resting alpha power was improved after executive attention *** significant difference in P2 was found between the two groups in analogical reasoning or perception but the experimental group showed a larger late positive component than the active control group in analogical *** also found that the late positive component mediated the relationship between the N2 of anti-saccade trials and analogical reasoning reaction times in the experimental *** further discussed the role of executive attention in the analogical reasoning process,which may pave the way for the future reliable improvement of fluid intelligence.

关键词： Analogical reasoning Executive attention Cognitive intervention Anti-saccade task Electroencephalography

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Psychological impact of coronavirus disease 2019 (COVID-19) social distancing mandates on trauma survivors

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Global Health Journal 2022年第3期6卷 174-179页

作者： Maggie M.Parker Stephanie F.Dailey ADiona Emmanuel Andrew Campbell graduate school of education and Human Development George Washington UniversityWashington D.C.20052USA College of education and Human Development George Mason UniversityFairfaxVA 22030USA psychology and Counseling Department Hood CollegeFrederickMD 21701USA

Objective:Despite recognition that coronavirus disease 2019(COVID-19)pandemic created an unprecedented impact on global mental health,information on the psychological health among trauma survivors during the COVID-19 pandemic is *** sought to examine psychological outcomes among individuals with preexisting traumatic experiences during ***:We sampled 1242 adults in the mid-Atlantic region of the United States under a state-issued Phase 1 stay-at-home mandate to examine associations between pre-pandemic trauma exposure as measured by the Brief Trauma Questionnaire(BTQ)and anxiety and depression,as measured by the Patient Reported Outcome Scale Anxiety and Depression(PROMIS-A and PROMIS-D).Results:Pre-pandemic trauma exposure among the sample was reported,with 281(22.6%)participants identifying as experiencing one trauma,209(16.8%)reporting two,and 468(37.7%)reporting three or *** reported experiences of trauma increased,so did participant anxiety and depressive ***-way Analysis of Variance indicated that reported trauma was significantly positively correlated with anxiety(P<0.01)and depressive symptomatology(P<0.01).Conclusion:Findings highlight the immense psychological toll of the COVID-19 pandemic,specifically with individuals who were previously exposed to *** health officials can encourage physicians,employers,and universities to screen patients,employees,and students to assess previous trauma,psychological functioning,and risk *** between physicians and mental health providers including psychiatrists,psychologists,counselors,and social workers to provide evidence informed rapid coordination of care can better meet the global mental health crisis that is arising as a result of this unprecedented global trauma.

关键词： Coronavirus disease 2019(COVID-19) Trauma Risk factors Psychological distress Mental health

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Research and Exploration of Ideological and Political education in the Course of Pathophysiology

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Open Journal of Applied Sciences 2024年第5期14卷 1364-1379页

作者： Tongtong Lv Qiong Wang Yanhua Zhang Xiaochun Peng Department of Pathophysiology School of Basic Medicine Health Science Center Yangtze University Jingzhou China Department of Nursing Health Science Center Yangtze University Jingzhou China Department of Physiology School of Basic Medicine Health Science Center Yangtze University Jingzhou China Laboratory of Oncology Center for Molecular Medicine School of Basic Medicine Health Science Center Yangtze University Jingzhou China

Course based ideological and political education (CIPE) is an important way to improve the quality of ideological and political work and talent cultivation. This study explores for the first time the implementation of ideological and political education in the teaching of pathophysiology courses, and also analyzes the evaluation of student psychological status and the importance of mental health education in the implementation of IPE courses. A survey was conducted on 211 students at Yangtze university to understand their motivation and behavior towards learning ideological, political, and pathophysiological courses. In addition, a questionnaire survey was used to explore the relationship between pathophysiology and ideological and political courses, as well as the importance of their satisfaction with the implementation of ideological and political courses in pathophysiology and mental health education. The research results indicate that factors such as educational background and gender differences affect the learning of CIPE. graduate students are more interested in ideological and political courses, while female students find it difficult to study pathophysiology;In addition, the results of one-way ANOVA indicate that the implementation effect of IPE in pathophysiology courses depends on the level of interest in IPE and pathophysiology courses, the level of consideration for the importance of professional courses, the professional gains after studying pathophysiology, and the level of understanding of the relationship between IPE and CIPE. 81.04% of students believe that in the CIPE process, telling stories by teachers themselves is the most popular way of communication and education. This reflects the importance of mental health education from the perspective of CIPE. In addition, this study also indicates that PBL and flipped classroom teaching models are popular teaching models in CIPE. This study is beneficial for promoting the improvement and implementation

关键词： Pathophysiology Curriculum Ideological and Political education Higher education psychology Questionnaire Survey

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Processing Chinese hand-radicals activates the medial frontal gyrus A functional MRI investigation

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Neural Regeneration Research 2013年第20期8卷 1837-1843页

作者： Qing-Lin Wu Yu-Chen Chan Joseph P.Lavallee Hsueh-Chin Chen Kuo-En Chang Yao-Ting Sung Department of educational psychology and Counseling Taiwan Normal University Institute of Learning Sciences Tsing Hua University school of education and Applied Linguistics Ming Chuan University graduate Institute of Information and Computer education Taiwan Normal University

Embodied semantics theory asserts that the meaning of action-related words is neurally represented through networks that overlap with or are identical to networks involved in sensory-motor processing. While some studies supporting this theory have focused on Chinese characters, less attention has been paid to their semantic radicals. Indeed, there is still disagreement about whether these radicals are processed independently. The present study investigated whether radicals are processed separately and, if so, whether this processing occurs in sensory-motor regions. Materials consisted of 72 high-frequency Chinese characters, with 18 in each of four categories： hand-action verbs with and without hand-radicals, and verbs not related to hand actions, with and without hand-radicals. Twenty-eight participants underwent functional MRI scans while reading the characters. Compared to characters without hand-radicals, reading characters with hand-radicals activated the right medial frontal gyrus. Verbs involving hand-action activated the left inferior parietal lobule, possibly reflecting integration of information in the radical with the semantic meaning of the verb. The findings may be consistent with embodied semantics theory and suggest that neural representation of radicals is indispensable in processing Chinese characters.

关键词： neural regeneration neuroimaging functional MRI hand-radical radical representation Chinese character recognition embodied semantics semantic function Chinese learning grants-supported paper neuroregeneration

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The Relationship between College graduate’s Dual Self-Consciousness and Job Search Clarity: The Mediating Role of Perceived Stress

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International Journal of Mental Health Promotion 2022年第2期24卷 207-217页

作者： Tinghu Kang Yang Li Jiandong Guo Xingwen Ma Fatema Akhter Hiramoni Md Zahir Ahmed Mary C.Jobe Oli Ahmed school of psychology Northwest Normal UniversityLanzhou730070China College of education Northwest Normal UniversityLanzhou730070China school of Teacher education Yuxi Normal UniversityYuxi653100China Department of Admissions and Employment Service Northwest Normal UniversityLanzhou730070China Department of Economics Sheikh Hasina UniversityNetrokona2410Bangladesh Department of Psychological and Brain Sciences The George Washington UniversityWashington DC20052USA Department of psychology University of ChittagongChattogram4331Bangladesh

The aim of the study was to explore the relationship between college graduates’dual self-consciousness,job search clarity and perceived stress,and reveal the mediating role of perceived stress between dual self-consciousness and job search *** this study,467 college graduates were investigated using the Dual Self-Consciousness Scale,Job Search Clarity Scale,and Perceived Stress *** controlling for gender,age,and region,the results revealed that:(1)private self-consciousness has a signiﬁcant positive predictive effect on job search clarity;(2)perceived stress has a signiﬁcant negative predictive effect on job search clarity;(3)perceived stress plays partial mediation effects between private self-consciousness and job search clarity;(4)perceived stress plays complete mediation effects between public self-consciousness and job search clarity;(5)perceived stress has suppressing effects between public self-consciousness and job search clarity.

关键词： Private self-consciousness public self-consciousness job search clarity perceived stress Suppressing effects

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Research on Career Identity in China:A Literature Review

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International Journal of Mental Health Promotion 2023年第2期25卷 153-172页

作者： Huaruo Chen Ya Wen Fei Liu Yihong Zhao Zhiyao Xie Xuehui Zhang College of education Science and Technology Nanjing University of Posts and TelecommunicationsNanjing210023China Center for Research and Reform in education Johns Hopkins UniversityBaltimore21218USA school of Teachers and education Nanjing Xiaozhuang UniversityNanjing211171China school of education Science Nanjing Normal UniversityNanjing210097China school of education Science Huaiyin Normal UniversityHuai’an223300China Publicity Department of Weifang Municipal Committee Weifang261071China Jiangsu Health Vocational College Nanjing210029China

Career identity is one of the important topics to study the psychological problems of employees,especially after the outbreak of *** a populous country in the world,China has a large number of employees from all walks of life,and its research on career identity has attracted more and more ***,this study aims to sort out the history,characteristics,and trends of the research on career identity in China through a literature review,which can help more scholars pay attention to China’s career identity *** this study,Citespace is used to statistically analyze the selected literature from China’s National Knowledge Infrastructure(CNKI)and Web of Science(WOS).The results show that:(1)The historical evolution of career identity research in China can be divided into three stages:germination,development and maturity.(2)From the perspective of cooperation between authors and institutions,researchers tend to do independent research,mainly focusing on the research in the field of psychology.(3)From the key words,career identity and employability are the main high-frequency words.(4)From the cluster analysis,the research focuses mainly include social support,teachers’career identity,influencing factors,and job involvement.(5)From the emergent analysis,it can be seen that the research on roles and differences between urban and rural areas is weakening,and the research on factors such as job satisfaction is gradually strengthening as the frontier ***,according to the existing analysis results,this study predicts the future trend of career identity in China and thinks that it will extend from the fields of concept explanation,interdisciplinary research,scientific research tools,and so on.

关键词： Career identity scientific knowledge maps historical evolution research hot spot career education

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