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The Institute of Urology, Peking University prostatectomy score： a simple preoperative classification of prostate cancer for predicting surgical difficulty and risk

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Asian Journal of Andrology 2018年第6期20卷 581-586页

作者： Bing-Lei Ma Lin Yao Wei Yu Yu Wang Hai-Feng Song Zhe-Nan Zhang Si-Meng Lu Qian Zhang Zhi-Song He Jie Jin Li-Qun Zhou Department of Urology Peking University First Hospital and Institute of Urology Peking University Beijing 100034 China

Traditional laparoscopic radical prostatectomy is a treatment choice in many developing countries and regions for most patients with localized prostate cancer; however, no system for predicting surgical difficulty and risk has been established. This study aimed to propose a simple and standard preoperative classification system of prostate cancer using preoperative data to predict surgical difficulty and risk and to evaluate the relationship between the data and postoperative complications. We collected data from 236 patients and divided them into three groups to evaluate and validate the relationships among preoperative, operative, and postoperative data. This new scoring system is based on the body mass index, ultrasonic prostate volume, preoperative prostate-specific antigen level, middle lobe protrusion, and clinical stage. In the scoring group, we classified 89 patients into two groups： the low-risk group （score of 〈4） and high-risk group （score of ~4）, and then compared the postoperative data between the two groups. The positive surgical margin rate was higher in the high-risk group than low-risk group. The results in validation Groups A and B were similar to those in the scoring group. The focus of our scoring system is to allow for preliminary assessment of surgical difficulty by collecting the patients＇ basic information. Urologists can easily use the scoring system to evaluate the surgical difficulty and predict the risks of a positive surgical margin and urinary incontinence in patients undergoing laparoscopic radical prostatectomy.

关键词： laparoscopic radical prostatectomy prostate cancer scoring system surgical difficulty and risk

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Peking University Third Hospital score:a comprehensive system to predict intra-operative blood loss in radical nephrectomy and thrombectomy

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Chinese Medical Journal 2020年第10期133卷 1166-1174页

作者： Zhuo Liu Xun Zhao Hong-Xian Zhang Run-Zhuo Ma Li-Wei Li Shi-Ying Tang Guo-Liang Wang Shu-Dong Zhang Shu-Min Wang Xiao-Jun Tian Lu-Lin Ma departm ent of Urology Peking University Third HospitalBeijing 100191China Health Science Center Peking UniversityBeijing 100191China Department of Ultrasound Peking University Third HospitalBeijing 100191China.

Background:Radical nephrectomy and thrombectomy is the standard surgical procedure for the treatment of renal cell carcinoma (RCC) with tumor thrombus (TT). But the estimation of intra-operative blood loss is only based on the surgeon’s experience. Therefore, our study aimed to develop Peking University Third Hospital score (PKUTH score) for the prediction of intra-operative blood loss volume in radical nephrectomy and thrombectomy.Methods: The clinical data of 153 cases of renal mass with renal vein (RV) or inferior vena cava tumor thrombus admitted to Department of Urology, Peking University Third Hospital from January 2015 to May 2018 were retrospectively analyzed. The total amount of blood loss during operation is equal to the amount of blood sucked out by the aspirator plus the amount of blood in the blood-soaked gauze. Univariate linear analysis was used to analyze risk factors for intra-operative blood loss, then significant factors were included in subsequent multivariable linear regression analysis.Results: The final multivariable model included the following three factors: open operative approach (P < 0.001), Neves classification IV (P < 0.001), inferior vena cava resection (P = 0.001). The PKUTH score (0-3) was calculated according to the number of aforementioned risk factors. A significant increase of blood loss was noticed along with higher risk score. The estimated median blood loss from PKUTH score 0 to 3 was 280 mL (interquartile range [IQR] 100-600 mL), 1250 mL (IQR 575-2700 mL), 2000 mL (IQR 1250-2900 mL), and 5000 mL (IQR 4250-8000 mL), respectively. Meanwhile, the higher PKUTH score was, the more chance of post-operative complications (P = 0.004) occurred. A tendency but not significant overall survival difference was found between PKUTH risk score 0vs. 1 to 3 (P = 0.098).Conclusion: We present a structured and quantitative scoring system, PKUTH score, to predict intra-operative blood loss volume in radical nephrectomy and thrombectomy.

关键词： Renal cell carcinoma Venous thrombosis Blood loss Inferior vena cava

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Peking University Health Science Center Model of Clinica Pharmacy Education and Clinical Pharmacist Services

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Chinese Medical Journal 2016年第23期129卷 2890-2894页

作者： Zi-Hao Chen Yi-Min Cui Yino Zhou Zi-Ning Wang Yang Ke Peking University Health Science Center Beijing 100191 China Department of Pharmacy Peking University First Hospital Beijing 100034 China

In the 1950s, clinical pharmacy emerged in the United States and gradually developed into an indispensable component of the clinical services system, The American College of Clinical Pharmacy defines clinical pharmacy... 详细信息

关键词： Clinical Pharmacy Education Clinical Pharmacist Services Pharmaceutical Sciences

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Celebrating 90 years of Peking University School of Life Sciences(1925–2015)

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Science China(Life Sciences) 2015年第11期58卷 1055-1056页

作者： XU ZhiHong ZHU ZuoYan School of Life Sciences Peking University

The Department of Biology at Peking University was established in 1925,with Mr.Tan Xi Hong as its inaugural department head.In 1993,the department was renamed the School of Life Sciences.During the past 90 years,a steady stream of students has enrolled in the department in order to explore the secrets of life and to dedicate themselves to the advancement of society.

关键词：生命科学学院北京大学生物学

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SPECIAL ISSUE： RELIGION AND SOCIETY： CROSS-CULTURAL COMMUNICATION：Peking University＇s role in China＇s Anti-Christian Movement in 1922-1927

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Social Sciences in China 2010年第1期31卷 184-197页

作者： Chen Yiyi Peking University

本文阐述了北京大学知识分子在中国20世纪初的非基督教运动中所起的作用，尤为重视北京大学学者中的“非主流”观点。虽然北京大学大部分知识分子的观点和反基督教的主流舆论相吻合，但是也有许多学者表现出了高度的理智和宽容，警醒“... 详细信息

本文阐述了北京大学知识分子在中国20世纪初的非基督教运动中所起的作用，尤为重视北京大学学者中的“非主流”观点。虽然北京大学大部分知识分子的观点和反基督教的主流舆论相吻合，但是也有许多学者表现出了高度的理智和宽容，警醒“用宗教式的狂热来进行反宗教运动”属于过激行为。这种众口一声中的少数派声音的存在，反映了一个文化的成熟、城府和健康。在今天中华民族力图重振文化大国形象的努力中，仍然有借鉴意义。

关键词：北京大学基督教跨文化交际运动中国社会宗教文化价值观

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Practical 2.45-GHz microwave-driven Cs-free Hˉ ion source developed at Peking University

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Chinese Physics B 2018年第10期27卷 477-483页

作者：张滔彭士香武文斌任海涛张景丰温佳美马腾昊蒋耀湘孙江郭之虞陈佳洱 SKLNPT & IHIE School of Physics Peking University Beijing 100871 China

A practical 2.45-GHz microwave-driven Cs-free H^- source was improved based on the experimental H^- source at Peking University（PKU）. Several structural improvements were implemented to meet the practical requirements of Xi＇an Proton Application Facility（XiPaf）. Firstly, the plasma chamber size was optimized to enhance the plasma intensity and stability. Secondly, the filter magnetic field and electron deflecting magnetic field were enhanced to reduce co-extracted electrons. Thirdly, a new two-electrode extraction system with farther electrode gap and enhanced water cooling ability to diminish spark and sputter during beam extraction was applied. At last, the direct H^- current measuring method was adopted by the arrangement of a new pair of bending magnets before Faraday cup（FC） to remove residual electrons. With these improvements, electron cyclotron resonance（ECR） magnetic field optimization experiments and operation parameter variation experiments were carried out on the H^- ion source and a maximum 8.5-mA pure H^- beam was extracted at 50 kV with the time structure of 100 Hz/0.3 ms. The root-mean-square（RMS） emittance of the beam is 0.25 Π·mm·mrad. This improved H^- source and extraction system were maintenance-free for more than 200 hours in operation.

关键词： electron cyclotron resonance （ECR） ion source hydrogen plasma negative ion beam plasma application

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The Yuanpei Program in Peking University:A case study of curriculum innovation

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Frontiers of Education in China 2016年第3期11卷 423-425页

作者： MA Liping Peking University

Wanying Wang.Dordrecht,The Netherlands:Springer,2014.xvii+165 pp.,(paperback),109.99€,ISBN:978-364-243-803-5.General education,one of the most prominent themes in contemporary higher education,has attracted wide attention from international academia during the last few decades.Wang’s newly published book,The Yuanpei Program in Peking University:A case study of curriculum innovation,is a pioneering study attempting to find out how general education reforms have evolved in the context of China.Within the goal of developing world-class universities,this book contributes to both theory and practice.

关键词： education has peking

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Cs_2 Te photocathode fabrication system at Peking University

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Chinese Physics C 2012年第5期36卷 475-478页

作者：戴劲全胜文常城刘克新赵夔 Institute of Heavy Ion Physics Peking University

A cesium telluride （Cs 2 Te） photocathode with a quantum efficiency of 13% at 253.7 nm （radiant incidence 200 μW/cm 2 ） is fabricated by tellurium and cesium vapor deposition onto a stainless-steel substrate. The cesium telluride cathode will be used to provide a high-brightness electron beam source for the 3＋1/2 photo-injector at Peking University. The design of the system, the fabrication procedures and the preliminary experimental results are presented in this paper.

关键词： photo-injector photocathode Cs 2 Te quantum efficiency

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Preliminary design and multipacting simulation of a SRF quarter wave electron gun at Peking University

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Chinese Physics C 2014年第5期38卷 87-92页

作者：范培亮朱凤全胜文刘克新 State Key Laboratory of Nuclear Physics and Technology Peking University

Peking University is designing a new SRF gun that is composed of a quarter wave resonator （QWR） and an elliptical cavity. Compared to the elliptical cavity, the QWR is sufficiently compact at the same frequency and its electric field is quasi-DC. The RF parameters are determined by optimization of QWR cavity structure and the possible multipacting locations are analyzed by 2D MP simulation. The simulation results show that multipacting is not a critical issue for our optimized cavity structure.

关键词： QWR multipacting electron gun

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基于变革管理视角对三十年来机构改革的审视（英文）

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Social Sciences in China 2016年第1期37卷 57-74页

作者：周志忍徐艳晴 Chen Yang School of Government Peking University School of Politics & Public Administration Hainan University

党中央决定成立全面深化改革领导小组,负责改革的总体设计、统筹协调、整体推进、督促落实。这意味着变革管理被提上重要议事日程。从变革管理角度系统梳理和审视改革开放以来国务院七轮机构改革历程,国务院机构设置变革呈现出明显的渐... 详细信息

党中央决定成立全面深化改革领导小组,负责改革的总体设计、统筹协调、整体推进、督促落实。这意味着变革管理被提上重要议事日程。从变革管理角度系统梳理和审视改革开放以来国务院七轮机构改革历程,国务院机构设置变革呈现出明显的渐进和稳健特征,职能转变是历次改革的核心和亮点。政府职能转变呈现出明显的两段论特色:第一阶段的重点是政府经济管理职能的转变;第二阶段的重点是加强和改善宏观调控,强化社会管理和公共服务职能。但就方案设计而言,近10年来有关职能转变的目标和措施等具体性方面明显不足,具体措施及其成效与三轮机构改革方案之间的关系难以确立。因此,"机构改革是否也需要改革"成为新的实践命题,需要从战略定位、推进方式、公共责任、总体设计等方面进行思考。

关键词：机构改革职能转变变革管理

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