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World Journal of Clinical Cases 2024年第11期12卷 1909-1917页

作者： Maja Milickovic Petar Rasic Sofija Cvejic Dejana Bozic Djordje Savic Tanja Mijovic Sava Cvetinovic Slavisa M Djuricic Department of Abdominal Surgery Mother and Child Health Care Institute of Serbia"Dr.Vukan Cupic"Belgrade 11000Serbia Faculty of Medicine University of BelgradeBelgrade 11000Serbia Department of radiology The Children’s University HospitalBelgrade 11000Serbia Department of Clinical Pathology Mother and Child Health Care Institute of Serbia"Dr.Vukan Cupic"Belgrade 11000Serbia Faculty of Medicine University of Banja LukaBanja Luka 78000Bosnia and Herzegovina

Splenic hamartomas(SHs)are uncommon,benign vascular lesions of unclear etiology and are mostly found incidentally on abdominal images,at surgery,or at *** the first case description,in 1861,less than 50 pediatric SH cases have been reported in the *** this article,we have performed an analysis of all SH cases in children published in the literature to date and presented our case of an 8-year-old male with *** lesions in children were shown to cause symptoms more often than in the adult *** observed SH sizes in children ranged from a few millimeters to 18 cm,and the symptomatic lesions were mostly larger or *** most common clinical finding was *** of hypersplenism were present in children with a single SH larger than 4.5 cm(diameter range:4.5-18.0 cm)and in those with multiple hamartomas,ranging from a few millimeters to 5 *** percent of patients with available laboratory findings had hematological abnormalities such as anemia,thrombocytopenia,or *** symptoms and signs included abdominal pain,recurrent infections,fever,night sweats,lethargy,growth retardation,and weight *** use of multiple imaging modalities may suggest the preoperative diagnosis of a splenic mass in children and determine the therapeutic ***,the final diagnosis of SH relies on histopathological ***,including total or partial splenectomy(PS),is the mainstay of SH *** M et *** in children WJCC https://*** 1910 April 16,2024 Volume 12 Issue 11 Although total splenectomy carries a greater risk of overwhelming post-splenectomy infection than PS it has remained the most performed surgical procedure in children with *** the majority of pediatric patients with symptomatic SH,resolution of symptoms and resolution or improvement of cytopenias occurred after surgical treatment.

关键词： Splenic hamartoma pediatric Splenoma Clinical features Radiological features Histopathology Treatment

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Vulvovaginal myeloid sarcoma with massive pelvic floor infiltration: A case report and review of literature

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World Journal of Clinical Cases 2022年第23期10卷 8312-8322页

作者： Jia-Xi Wang Heng Zhang Gang Ning Li Bao Department of radiology Key Laboratory of Obstetric&Gynecologic and Pediatric Diseases and Birth Defects of Ministry of EducationWest China Second University HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of radiology Renshou Maternity and Child Health HospitalMeishan 620500Sichuan ProvinceChina

BACKGROUND Myeloid sarcoma(MS),including isolated and leukaemic MS,is an extramedullary myeloid *** can involve any anatomical site,but MS of the female genital tract is rare,with the ovaries and uterine body and cervix being the most commonly seen *** of the vagina and vulva is extremely *** SUMMARY We report a rare case of MS with involvement of the vulva and vagina and massive infiltration of the pelvic floor.A 26-year-old woman presented with a vulvar mass,irregular vaginal bleeding and night *** resonance imaging demonstrated an ill-defined,irregular vulvovaginal mass with massive involvement of the paravaginal tissue,urethra,posterior wall of the bladder,and pelvic *** signal and enhancement of the huge mass was homogeneous without haemorrhage or *** emission tomography/computed tomography showed high fluorodeoxyglucose uptake by the *** blood count detected blast *** mass and bone marrow biopsies were performed,and immunohistochemistry confirmed the diagnosis of acute myeloid leukaemia(M-2 type,FAB classification)and vulvovaginal *** patient was treated with induction chemotherapy followed by allogeneic haematopoietic stem cell transplantation,and achieved complete remission.A systemic review of the literature on vulvovaginal MS was conducted to explore this rare entity’s clinical and radiological *** Vulvovaginal MS is extremely *** of vulvovaginal MS can only be confirmed *** though its clinical and imaging presentations are nonspecific,MS should be considered in the differential diagnosis of a newly developed T2-hyperintense,homogeneously enhanced vulvovaginal mass,especially in a patient with suspected haematological malignancy.

关键词： Myeloid sarcoma Vagina Vulva Acute myeloid lukaemia Imaging examination Case report

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Purulent Pleurisy Revealing Lymphoblastic Lymphoma Type T: A pediatric Case Report

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Open Journal of pediatrics 2022年第5期12卷 827-831页

作者： Fatima Ezzahra Tahiri Karima Elfakiri Ghizlaine Draiss Nourredine Rada Mohammed Bouskraoui Btissam Zouita Dounia Basraoui Hicham Jalal pediatric A Department Pediatric Pulmonology Unit Mother and Child Hospital University Hospital Mohammed VI Marrakesh Marrakesh Morocco pediatric radiology Department Mother and Child Hospital University Hospital Mohammed VI Marrakesh Marrakesh Morocco

Lymphoma is a very common cancer in the pediatric population, and its modes of revelation are very variable. Case report: A 7-year-old patient was admitted for purulent pleurisy, whose cytological study of the pleural fluid isolated lymphoblastic cells in favor of a T-type lymphoblastic lymphoma, a very rare mode of revelation in current practice. Conclusion: pediatric lymphoma takes on different aspects, and it is important to look for it systematically in order to ensure adequate management.

关键词： Pleural Effusion Pleural Puncture Cytology T Lymphoma

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Diagnosis,treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children:experts'consensus statement updatedforthe Omicron variant

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World Journal of pediatrics 2024年第3期20卷 272-286页

作者： Rong-Meng Jiang Zheng-De Xie Yi Jiang Xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Yun-Xiao Shang Bao-Ping Xu Zhi-Sheng Liu Gen Lu Ji-Kui Deng Guang-Hua Liu Xiao-Chuan Wang Jian-She Wang Lu-Zhao Feng Wei Liu Yi Zheng Sai-Nan Shu Min Lu Wan-Jun Luo Miao Liu Yu-Xia Cui Le-Ping Ye A-Dong Shen Gang Liu Li-Wei Gao Li-Juan Xiong Yan Bai Li-Kai Lin Zhuang Wei Feng-Xia Xue Tian-You Wang Dong-Chi Zhao Jian-Bo Shao Daniel Kwok-keung Ng Gary Wing-kin Wong Zheng-Yan Zhao Xing-Wang Li Yong-Hong Yang Kun-Ling Shen Diagnosis and Treatment Center of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing Key Laboratory of pediatric Respiratory Infection Diseases Key Laboratory of Major Diseases in ChildrenMinistry of EducationNational Clinical Research Center for Respiratory DiseasesResearch Unit of Critical Infection in ChildrenChinese Academy of Medical Sciences2019RU016Laboratory of Infection and VirologyBeijing Pediatric Research InstituteBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of pediatrics Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Respiratory Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China Department of pediatrics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Respiratory Shenzhen Children's HospitalShenzhen 518038China Department of pediatric Respiratory Shengjing Hospital Affiliated to China Medical UniversityShenyang 110004China Department of Respiratory Beijing Children's HospitalCapital Medical UniversityNational Clinical Research Center for Respiratory DiseasesNational Center for Children's HealthBeijing 100045China Department of Neurology Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China Department of Respiratory Guangzhou Women and Children's Medical CenterGuangzhou 510623China Department of Infectious Diseases Shenzhen Children's HospitalShenzhen 518038China Department of pediatrics Fujian Branch of Shanghai Children's Medical CenterFujian Children's HospitalFuzhou350005China Department of Clinical Immunology and Allergy Children's Hospital of Fudan UniversityNational Center for Children's HealthShanghai 201102China Department of Infectious Diseases Children's Hospital of Fudan UniversityNational Center for Children's Health.Shanghai

It has been more than 3 years since the novel coronavirus(SARS-CoV-2)pandemic raged *** coronavirus disease 2019(COVID-19)has greatly influenced human *** to data from the World Health Organization(WHO),there were ove... 详细信息

关键词： prevention infection statement

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Magnetic resonance imaging evaluation of head and neck involvement in IgG4-related disease

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Asian Pacific Journal of Tropical Medicine 2023年第6期16卷 276-283页

作者： Umur Anil Pehlivan Kamil Karaali Hatice Deniz Ilhan Mehmet Soy Didem Arslan Omer Kaya Rabia Miray Kisla-Ekinci Burcak Cakir-Pekoz Ummuhan Cay Arbil Acikalin Ahmet Muhtesem Agildere Department of radiology Başkent University Adana Dr.Turgut Noyan Application and Research CenterAdanaTurkey Department of radiology Akdeniz University Faculty of MedicineAntalyaTurkey Department of Ophthalmology Akdeniz University Faculty of MedicineAntalyaTurkey Department of Internal Medicine and Rheumatology Bahçelievler Medical ParkAltınbaşUniversity Faculty of MedicineİstanbulTurkey Department of Internal Medicine and Rheumatology Çukurova University Faculty of MedicineAdanaTurkey Department of radiology Çukurova University Faculty of MedicineAdanaTurkey Department of pediatric Rheumatology Adana City Training and Research HospitalAdanaTurkey Department of radiology Adana City Training and Research HospitalAdanaTurkey Department of pediatric Infectious Disease Çukurova University Faculty of MedicineAdanaTurkey Department of Pathology Çukurova University Faculty of MedicineAdanaTurkey Department of radiology Başkent University Faculty of MedicineAnkaraTurkey

Objective:To evaluate the radiological features of IgG4-related disease(IgG4-RD)in the head and neck ***:In this radiology-based study,radiological features,clinical,laboratory,pathological findings,and prognosis of nine patients with head and neck involvement diagnosed with IgG4-RD were investigated ***:The median age of the patients was 38 years(range:2.5-79 years),and there were six males and three *** most common symptoms and clinical findings of the patients were eyelid and lacrimal gland swelling,painless exophthalmos,and *** most common site of involvement on MRI was the *** involvement was followed by branches of the trigeminal nerve,sinonasal cavity,cervical lymph nodes,and dural *** most common and remarkable imaging features were T2 hypointensity and diffuse homogeneous contrast ***:Head and neck involvement of the IgG4-RD,has specific imaging features that can help with ***,early diagnosis and better outcomes can be achieved with increasing awareness of these features of this relatively new pathology.

关键词： IgG4 Head and neck imaging Magnetic resonance imaging Orbit Perineural spreading

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Assessment of bone turnover and bone quality in type 2 diabetic bone disease： current concepts and future directions

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Bone Research 2016年第1期4卷 1-9页

作者： Mishaela R Rubin Janina M Patsch Metabolic Bone Disease unit Department of Medicine Columbia University College of P&S New York USA Division of General radiology and pediatric radiology Department of Biomedical Imaging and Image-Guided Therapy Medical University of Vienna Vienna Austria

Substantial evidence exists that in addition to the well-known complications of diabetes, increased fracture risk is an important morbidity. This risk is probably due to altered bone properties in diabetes. Circulating biochemical markers of bone turnover have been found to be decreased in type 2 diabetes （T2D） and may be predictive of fractures independently of bone mineral density （BMD）. Serum sclerostin levels have been found to be increased in T2D and appear to be predictive of fracture risk independent of BMD. Bone imaging technologies, including trabecular bone score （TBS） and quantitative CT testing have revealed differences in diabetic bone as compared to non-diabetic individuals. Specifically, high resolution peripheral quantitative CT （HRpQCT） imaging has demonstrated increased cortical porosity in diabetic postmenopausal women. Other factors such as bone marrow fat saturation and advanced glycation endproduct （AGE） accumulation might also relate to bone cell function and fracture risk in diabetes. These data have increased our understanding of how T2D adversely impacts both bone metabolism and fracture risk.

关键词： bone Assessment of bone turnover and bone quality in type 2 diabetic bone disease type

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One step minilaparotomy-assisted transmesenteric portal vein recanalization combined with transjugular intrahepatic portosystemic shunt placement: A novel surgical proposal in pediatrics

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World Journal of Gastroenterology 2017年第15期23卷 2811-2818页

作者： Gloria Pelizzo Pietro Quaretti Lorenzo Paolo Moramarco Riccardo Corti Marcello Maestri Giulio Iacob Valeria Calcaterra Department of Clinical SurgicalDiagnostic and Pediatric SciencesUniversity of Pavia pediatric Surgery unit Ospedale dei Bambini“G.di Cristina”Istituto Mediterraneo di Eccellenza Pediatrica unit of Interventional radiology Fondazione IRCCS Policlinico San Matteo radiology Department IRCCS Policlinico San Matteo Foundation Department of Surgery IRCCS Policlinico San Matteo Foundation pediatric unit Department of Maternal and Children's HealthFondazione IRCCS Policlinico San Matteo Department of Internal Medicine and Therapeutics University of Pavia

Transjugular intrahepatic portosystemic shunt(TIPS) placement is a standard procedure for the treatment of portal hypertension complications. When this conventional approach is not feasible, alternative procedures for systemic diversion of portal blood have been proposed. A one-step interventional approach, combining minilaparotomy-assisted transmesenteric(MAT) antegrade portal recanalization and TIPS, is described in an adolescent with recurrent esophageal varice bleeding and portal cavernoma(PC). A 16-yearold girl was admitted to our unit because of repeated bleeding episodes over a short period of time due to esophageal varices in the context of a PC. A portal vein recanalization through an ileocolic vein isolation with the MAT approach followed by TIPS during the same session was performed. In the case of failed portal recanalization, this approach, would also be useful for varice endovascular embolization. Postoperative recovery was uneventful. Treatment consisting of propanolol, enoxaparin and a proton pump inhibitor was prescribed after the procedure. One month post-op, contrast enhanced computed tomography confirmed the patency of the portal and intrahepatic stent grafts. No residual peritoneal fluid was detected nor opacification of the large varices. Endoscopy showed good improvement of the varices. Doppler ultrasound confirmed the accelerated flow in the portal stent and hepatopetal flow inside the intrahepatic portal branches. Three months post-op, TIPS maintained its hourglass shape despite a slight expansion. Portal hypertension and life threatening conditions related to PC would benefit from one-step portal recanalization. MAT-TIPS is feasible and safe for the treatment of PC even in children. This minimally invasive procedure avoids or delays surgical treatment or re-transplantation when necessary in pediatric patients.

关键词：门 cavernoma 儿科 Transjugular intrahepatic portosystemic 分流帮助 Minilaparotomy 的 transmesenteric

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Cohort analysis of pediatric intussusception score to diagnose intussusception

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World Journal of Clinical Cases 2023年第21期11卷 5014-5022页

作者： Punwadee Rukwong Nathawit Wangviwat Teerasak Phewplung Palittiya Sintusek Department of pediatrics Phrapokklao HospitalChantaburi 22000MeuangThailand Division of Laboratory Medicine King Chulalongkorn Memorial HospitalBangkok 10330Thailand Department of radiology Chulalongkorn UniversityBangkok 10330Thailand Thai pediatric Gastroenterology Hepatology and Immunology Research UnitDivision of GastroenterologyDepartment of PediatricsKing Chulalongkorn Memorial HospitalChulalongkorn UniversityBangkok 10330Thailand

BACKGROUND Intussusception is a primary cause of intestinal obstruction in young *** diagnosis is associated with increased ***(USG)is the gold standard for diagnosis,but it is operator dependent and often unavailable in limited resource *** To study the clinical characteristics of intussusception including management and evaluation of the diagnostic accuracy of abdominal radiography(AR)and the promising parameters found in the pediatric intussusception score(PIS).METHODS Children with suspected intussusception in our center from 2006 to 2018 were *** manifestations,investigations,and treatment outcomes were *** images were interpreted by a pediatric *** of intussusception was composed of compatible USG and response with *** diagnostic value of the proposed PIS was *** Ninety-seven children were diagnosed with intussusception(2.06±2.67 years,62.9%male),of whom 74%were<2 years old and 37.1%were *** common manifestations of intussusception were irritability or abdominal pain(86.7%)and vomiting(59.2%).Children aged 6 mo to 2 years,pallor,palpable abdominal mass,and positive AR were the parameters that could discriminate intussusception from other mimics(P<0.05).Referral case was the only significant parameter for failure to reduce intussusception(P<0.05).AR to diagnose intussusception had a sensitivity of 59.2%.The proposed PIS,a combination of clinical irritability or abdominal pain,children aged 6 mo to 2 years,and compatible AR,had a sensitivity of 85.7%.CONCLUSION AR alone provides poor screening for *** proposed PIS in combination with common manifestations and AR data was shown to increase the diagnostic sensitivity,leading to timely clinical management.

关键词： Intussusception pediatric Specificity Sensitivity Abdominal radiography Diagnosis

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Histopathological and Ultrasound Correlation in Women Presenting with Breast Lumps in Yaoundé, Cameroon

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Open Journal of radiology 2023年第4期13卷 218-231页

作者： Yann Chris Mannel Eng Ambroise Merci Seme Engoumou Armel Philippe Awana Sandrine Prisca Ndongo Onembele Junie Annick Metogo Ntsama Odile Fernande Zeh Faculty of Medicine and Biomedical Sciences The University of Yaounde I Yaounde Cameroon Yaoundé Gyneco-Obstetrical and pediatric Hospital Yaounde Cameroon radiology unit Yaoundé University Teaching Hospital Yaounde Cameroon radiology unit Jamot Hospital Yaounde Cameroon Department of Biomedical Sciences University of Ngaoundere Ngaoundere Cameroon

Context: Breast cancer is very deadly among women with higher rates in the developing world. Imaging tools such as ultrasound, can be used to differentiate between the types of breast lumps. This study aimed to determine the value of ultrasound as a first-line examination in the diagnosis of breast masses. Methods: This was a retrospective cross-sectional study of women presenting with breast lumps from November 2022 to June 2023 at the Yaounde General Hospital, which lasted seven months, from November 2022 to June 2023. The sampling was exhaustive and consecutive. Association between variables was studied using the x2 test and concordance between ultrasound and histopathological findings was assessed using the Kappa correlation coefficient. Results: 234 women were included in the study. Their mean age was 46.3 ± 11.4 years. Overall, 15 (6.4%) lumps were benign while 219 (93.6%) were malignant. Triple negative (5.6%) was the most recurrent genomic classification. The correlation between the ultrasound and histopathological findings was significant, with an observed concordance rate at 85.1%, kappa = 0.322 and a p-value Conclusion: The performance of ultrasound in differentiating benign and malignant lesion was high. However, the discordant cases highlight the need for a diagnosis system which blends histopathological and radiological findings for an improved management of patients with breast lumps.

关键词： Ultrasound Histopathological Diagnosis Breast Lumps Yaoundé

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Comparison of 2D and 4D Flow MRI Measurements for Hemodynamic Evaluation of the Fontan Palliation

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Congenital Heart Disease 2023年第6期18卷 627-638页

作者： Elisa Listo Nicola Martini Stefano Salvadori Elisa Valenti Nicola Stagnaro Gianluca Trocchio Chiara Marrone Alberto Clemente Francesca Raimondi Pierluigi Festa Lamia Ait Ali Department of radiology IRCCS Istituto Giannina GasliniGenovaItaly U.O.C.Bioingegneria Gabriele Monasterio CNR-Tuscany FoundationPisaItaly Institute of Clinical Physiology CNR PisaItaly Cardiology unit IRCCS Istituto Giannina GasliniGenovaItaly pediatric Cardiology and GUCH unit Massa Gabriele Monasterio CNR-Tuscany FoundationMassaItaly Gabriele Monasterio CNR-Tuscany Foundation PisaItaly Department of Cardiology Azienda Ospedaliero-Universitaria MeyerFlorenceItaly Institute of Clinical Physiology CNR MassaItaly

Background:The assessment of Fontan circuit’sﬂow is traditionally evaluated by multiple through-plane phase-contrast MRI acquisitions(2Dﬂow),while recently,a single volumetric 4D-ﬂow MRI acquisition is emerging as a comprehensive tool for the hemodynamic evaluation in congenital heart ***:To compare 2D and 4D-ﬂow MRI measurements in patients after Fontan palliation and to evaluate parameters affecting potential ***:39 patients after Fontan palliation(23 males,age 22±11 years)who underwent cardiac MRI with 2D and 4D-ﬂow MRI acquisition were included in the *** all patients,bloodﬂow quantiﬁcation in the Fontan circuit and aorta by 2Dﬂow and by 4Dﬂow MRI acquisition blinding to the 2D results was *** agreement between 2D and 4D-ﬂow MRI was calculated as the intraclass correlation coefﬁcient(ICC).The mean absolute differences between 4D and 2Dﬂows were analyzed using linear regression ***:4D-ﬂow MRI acquisition time was slightly lower than 2D(7.6±1.8 min vs.9.4±3.3 min,p=0.03).Flow was slightly predominant in the right pulmonary artery(58%of total pulmonaryﬂow).Conduit/tunnel-pul-monary arteriesﬂow accounted for 60%of the Fontan *** between 2D and 4D was overall good-to-excellent from ICC:0.81795%CI:0.637–0.907 to 0.93295%CI:0.866–*** was no signiﬁcant inﬂu-ence of evaluated parameters on the agreement on 4D and 2Dﬂ***:4D-ﬂow MRI represents a valid tool in Fontan’sﬂow quantiﬁ*** larger studies are needed to conﬁrm our results and to evaluate the impact of advanced 4D-ﬂow MRI parameters on the prognostic stratiﬁcation in patients after Fontan palliation.

关键词： Fontan palliation fontanﬂows 4Dﬂow MRI 2Dﬂow MRI cardiac magnetic resonance

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