检索结果-南通市图书馆

Balancing early detection and over-screening:Evaluating colonoscopy's role in shaping colorectal cancer trends in Korea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第3期17卷 474-478页

作者： Di-Ping Luo Bo-Tao Xu Hui Zhang Tie-Fei He Department of Vascular surgery Zhuji People's HospitalZhuji 311800Zhejiang ProvinceChina Department of cardiothoracic surgery Zhuji People's HospitalZhuji 311800Zhejiang ProvinceChina Department of Emergency surgery Zhuji People's HospitalZhuji 311800Zhejiang ProvinceChina

This study discusses the impact of the increasing use of colonoscopy on the trends of colorectal cancer(CRC)in *** views are raised on the research methods and conclusions of Kim et *** emphasizes the need to carefully consider the balance between the benefits of early detection and the risks of *** letter also suggests directions for future research and policy considerations in the field of CRC screening and prevention in Korea.

关键词： Colorectal cancer Colonoscopy Screening policies Early detection Overscreening Artificial intelligence Molecular biomarkers Oncology research

Adnexal Sliding Hernia in an Infant: Clinical-Anatomical Case Report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of pediatrics 2025年第1期15卷 93-100页

作者： Ralf-Bodo Tröbs Grigore Cernaianu Matthias Nissen Department of General Visceral and Pediatric Surgery St. Vincenz Hopitals Paderborn Germany Division of pediatric surgery University Hospital Cologne Cologne Germany Department of pediatric surgery St. Maries Hospital Witten Ruhr-University of Bochum Sankt Elisabeth Gruppe Germany

We present a case report of laparoscopic herniorrhaphy in an infant with ovarian prolapse. Using this case study, we demonstrate the role of the ovarian ligamentous apparatus. A structure appearing like the male gubernaculum was identified. The anatomical and functional role of this “gubernaculum” will be the subject of discussion. Further detailed laparoscopic examinations are indicated to better understand the ligamentous anatomy of ovarian prolapse.

关键词： Inguinal Hernia Ovarian Prolapse Ovarian Descensus Sliding Hernia Gubernaculum

Role of Right Ventricular-Pulmonary Arterial Coupling Measured by Echocardiography in Predicting Right Ventricular Dysfunction after Cardiac surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiovascular surgery 2025年第1期15卷 1-11页

作者： Ismail Nasr El-Sokkary Esam Ahmed Khalil Mohammed Fawzy Eltaweel Ahmed Alherazi Mohammed Samy Bahaa Abdelgawad Elkhonezy Mohamed El Sayed Moussa Mohamed Ahmed Mosaad Zaki Ibrahim Abdel Fattah Yassin Mohamed Kamal Rehan Department of cardiothoracic surgery Faculty of Medicine Al-Azhar University Cairo Egypt Department of Cardiology Al-Azhar University Faculty of Medicine Cairo Egypt Department of cardiothoracic surgery Faculty of Medicine Menoufia University Shibin El Kom Egypt Department of cardiothoracic surgery Faculty of Medicine Alexandria University Alexandria Egypt Department of Internal Medicine Faculty of Medicine Beni Suef University Cairo Egypt

Background: The tricuspid annular plane systolic excursion (TAPSE) and pulmonary artery systolic pressure (PASP) is an indirect estimate of right ventricular-pulmonary arterial (RV-PA) coupling that has been shown to correlate with invasive measures. We aimed to assess the ability of the tricuspid annular plane systolic excursion/pulmonary systolic pressure ratio (TAPSE/PASP) as a measure for RV-PA coupling to predict the development of RV dysfunction after cardiac surgery. Methods: This prospective study was conducted on 100 patients with ischemic heart disease and undergoing cardiac surgery (coronary artery bypass graft (CABG)) with normal preoperative right ventricular function, classified according to RV function outcomes into 2 groups: Normal RV group (65 patients) and RV dysfunction group (35 patients). All cases underwent per and postoperative transthoracic echocardiography. Results: By using receiver operating characteristic curve analysis, pre-operative TAPSE/PASP ratio could significantly predict the RV dysfunction (P 0.58, with AUC of 94%, 88.6% sensitivity, and 89.2% specificity. Post-operative TAPSE/PASP Ratio could significantly predict the RV dysfunction (P 0.39, with AUC of 84%, 100% sensitivity, and 76.9% specificity. Pre-operative TAPSE/PASP ratio could significantly predict mortality (P Conclusion: The TAPSE/PASP ratio is an excellent tool for CABG patients for its ability to detect and predict the development of RV dysfunction after cardiac surgery, along with the prediction of mortality in post-operative CABG patients.

关键词： Right Ventricular Pulmonary Arterial Coupling Echocardiography Cardiac surgery

Activin A receptor type 1C single nucleotide polymorphisms associated with esophageal squamous cell carcinoma risk in Chinese population

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 39-51页

作者： Si-Yun Lin Hou Huang Jin-Jie Yu Feng Su Tian Jiang Shao-Yuan Zhang Lu Lv Tao Long Hui-Wen Pan Jun-Qing Qi Qiang Zhou Wei-Feng Tang Guo-Wen Ding Li-Ming Wang Li-Jie Tan Jun Yin Department of Thoracic surgery Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Affiliated to Fudan UniversityShanghai 200040China Department of cardiothoracic surgery The Affiliated People's Hospital of Jiangsu UniversityZhenjiang 212002Jiangsu ProvinceChina Department of Thoracic surgery Sichuan Cancer Hospital&InstituteChengdu 610042Sichuan ProvinceChina Department of cardiothoracic surgery Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210000Jiangsu ProvinceChina Department of Respiratory and Critical Care Medicine Shanghai Xuhui Central HospitalShanghai 200032China

BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and *** A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent *** To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han *** In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were *** SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction ***-Weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were *** Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male *** the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to *** ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.

关键词： Activin A receptor type 1C Single nucleotide polymorphisms Esophageal squamous cell carcinoma Genetic susceptibility Hospital-based cohort study

Left Ventricular End-Diastolic Dimension as an Outcome After Combined Mitral Valve surgery and CABG

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiovascular surgery 2025年第1期15卷 12-21页

作者： Walid Hammad Aboubakr Hasan Mansour Mohamed Elsayed Moussa Ashraf Ibrahim Zahra Sherif S. Eliwa cardiothoracic surgery Department Al-Azhar Faculty of Medicine Al-Azhar University Cairo Egypt Children of Egypt Abulreesh Hospital General Authority for Health Insurance Ministry of Health Cairo Egypt cardiothoracic surgery Department Shebin El Kom Teaching Hospital Shebin al-Kom Egypt

Background: Left ventricular size is a factor independently associated with increased mortality in mitral surgery, particularly, in the setting of ischemic mitral regurgitation (IMR). In some patients with dilated ventricles, reverse remodelling does not occur, with a high risk of residual or recurrent mitral regurgitation and therefore associated with worse outcome. We conducted multi-centers retrospective observational study on a cohort of patients who had combined CABG and mitral surgery for moderately severe IMR to correlate a relationship between perioperative left ventricular dimensions to postoperative mortality rates in both genders. Results: 287 patients had combined CABG and mitral valve surgery. The exclusion criteria were patients with very low function Conclusion: Failure of early ventricular remodeling with persistently elevated end systolic dimensions is a risk factor for postoperative death in both genders. Females gender will have an additional higher risk if the end diastolic dimensions remain elevated.

关键词： Left Ventricular Dimensions End Systolic Dimension End Diastolic Dimension

Relevance of epidemiology data in trauma management

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第9期13卷 65-67页

作者： Krishna Kumar Govindarajan Department of pediatric surgery Jawaharlal Institute of Postgraduate Medical Education and ResearchPuducherry 605006India

Trauma is a major cause of morbidity and mortality across the globe accounting for significant health *** of trauma care revolves round prevention,planning and execution of safety *** of the actual data regarding the type of trauma,affected age group,timings of trauma occurrence,involved part of the body constitute the initial steps in the building of the composite overview of the epidemiology of *** succession,would be the measures directed towards avoidance of trauma and capacity building of trauma center.

关键词： Trauma Epidemiology Injury Prevention Triage Registry Artificial Intelligence

Advanced hepatocellular carcinoma treatment strategies:Are transarterial approaches leading the way?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 22-27页

作者： Stefan Patauner Giovanni Scotton Francesca Notte Antonio Frena Department of General and pediatric surgery Bolzano Central Hospital-SABESBolzano 39100Trentino-Alto AdigeItaly

Hepatocellular carcinoma(HCC)is a leading cause of cancer-related mortality worldwide,with advanced stages posing significant treatment ***-though hepatic arterial infusion chemotherapy(HAIC)has emerged as a promising modality for treating advanced HCC,particularly in Asian clinical practice,its adoption in Western medicine remains limited due to a lack of large-scale randomized controlled *** editorial reviews and comments on the meta-analysis conducted by Zhou et al,which evaluates the efficacy and safety of HAIC and its combination strategies for advanced *** authors performed a comprehensive meta-analysis of various clinical trials and cohort studies comparing HAIC and its combinations to other first-line treatments,such as sorafenib and transarterial chemoembolization(TACE).In this work,HAIC showed significantly better results regarding overall survival and progression-free survival compared to sorafenib or TACE alone and their *** in combination with lenvatinib,ablation,programmed cell death 1 inhibitors,and radiotherapy further enhanced patient outcomes,indicating a synergistic *** editorial focuses on the critical role of multimodal treatment strategies in managing advanced *** advocates for a paradigm shift towards integrated treatment approaches to enhance survival rates and improve the quality of life in patients with advanced HCC.

关键词： Hepatocellular carcinoma Hepatic arterial infusion chemotherapy Transarterial chemoembolization Sorafenib Combined therapy

Clinical benefits and controversies of jejunostomy feeding in patients undergoing gastrectomy for gastric cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal surgery 2025年第3期17卷 422-426页

作者： Martino Munini Margot Fodor Alessio Corradi Antonio Frena Department of General and pediatric surgery Bolzano Central HospitalBolzano 39100Trentino-Alto AdigeItaly

Globally,gastric cancer ranks as the fifth most common malignancy and the third leading cause of cancer-related *** combined with periop-erative chemotherapy is currently the standard of care in locally advanced stages,but the completion rate of multimodal approach is influenced also by patient related *** is a well-known risk factor associated with poor oncological *** perioperative supplementation could lead to an im-provement of the nutritional *** article reviews and comments the retro-spective study conducted by Jaquet et al,which evaluates the impact of enteral nutrition by jejunostomy feeding in patients undergoing gastrectomy for *** authors included 172 patients,35%of whom received *** with optimized biological nutritional parameters(body mass index,albumin,prealbumin)showed reduced major complications(>III),according to the Dindo-Clavien classification,0(0%)vs 8(4.7%)(P=0.05).In the era of multimodal treatment,optimization of nutritional and performance status is integral part of the therapeutic strategy.

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang Yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu Xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation