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Managing spondylitis tuberculosis in a patient with underlying diabetes and hypothyroidism:A case report

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World Journal of Clinical Cases 2022年第21期10卷 7451-7458页

作者： Bernadette Dian Novita Ari Christy Muliono Sumi Wijaya Imelda Theodora Yudy Tjahjono Vincentius Diamantino Supit Vincentius Michael Willianto Department of Pharmacology and Therapy Faculty of MedicineWidya Mandala Surabaya Catholic UniversitySurabaya 60113East JavaIndonesia Department of Internal Medicine Faculty of MedicineWidya Mandala Surabaya Catholic UniversitySurabaya 60113Indonesia Department of Internal Medicine Premier Surabaya HospitalSurabaya 60111Indonesia Department of Internal Medicine Gotong Royong Surabaya HospitalSurabaya 60110Indonesia Faculty of Pharmacy Widya Mandala Surabaya Catholic UniversitySurabaya 60113Indonesia Department of Pathology Anatomy Faculty of MedicineWidya Mandala Surabaya Catholic UniversitySurabaya 60113Indonesia Department of Emergency Medicine Gotong Royong Surabaya HospitalSurabaya 60110Indonesia Department of General Medicine Faculty of MedicineWidya Mandala Surabaya Catholic UniversitySurabaya 60113Indonesia

BACKGROUND Tuberculosis(TB)remains one of the highest Asia’s health *** TB in diabetes mellitus(DM)and hypothyroidism patients is a rare case of extrapulmonary ***,there is a lack of therapeutic guidelines to treat spondylitis TB,particularly with type 2 DM(T2DM)and hypothyroidism as *** we present a case of spondylitis TB with T2DM and hypothyroidism in a relatively young patient and its therapeutic *** SUMMARY We report the case of a 35-year-old male patient from Surabaya,*** on anamnesis,physical examination,and magnetic resonance imaging,the patient has been categorized in stage II of spondylitis TB with grade 1 ***,the patient also had a high HbA1c level,high thyroid stimulating hormone,and low free T_(4)(FT_(4)),which indicated T2DM and hypothyroidism.A granulomatous process was observed in the histopathological *** antituberculosis drugs isoniazid and rifampicin were *** addition,insulin,empagliflozin,and linagliptin were given to control hyperglycemia conditions,and also levothyroxine to control *** The outcome was *** patient was able to do daily activities without pain and maintained normal glycemic and thyroid *** such cases,we recommend the treatment of spondylitis TB by spinal surgery,together with T2DM and hypothyroidism therapies,to improve the patients’*** early and non-invasive diagnoses and therapy are necessary.

关键词： Spondylitis tuberculosis Type 2 diabetes mellitus Hypothyroidism Case report

Physical exercises for preventing injuries among adult male football players:A systematic review

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Journal of Sport and Health Science 2022年第1期11卷 115-122页

作者： Jorge Pérez-Gómez JoséCarmelo Adsuar Pedro EAlcaraz Jorge Carlos-Vivas Health EconomyMotricity and Education(HEME)Research GroupFaculty of Sports SciencesUniversity of ExtremaduraCaceres 10003Spain UCAM Research Center for High Performance Sport Catholic University of MurciaMurcia 30107Spain Faculty of Sport Sciences Catholic University of MurciaMurcia 30107Spain

Background:Football is the most practised sport in the world and is associated with the risk of injuries in the *** studies have been published that identify injury prevention programs,but there is no review of the full body of evidence on injury prevention programs for use by football *** aim of this article was to carry out a systematic review of published studies on injury prevention programs for adult male footballers,identify points of common understanding and establish recommendations that should be considered in the design of injury prevention ***:PubMed and EMBASE databases were used to identify relevant published articles using the following keywords:"soccer"AND"injury"AND"prevention".Results:A total of 2512 studies were identified initially,but only 11 studies met the inclusion criteria,and their outcomes are *** revealed that injury prevention programs in football have focused on strength training,proprioceptive training,multicomponent programs(balance,core stability,and functional strength and mobility),and warm-up ***:Based on results from the studies analyzed,football players can lower the incidence of match and training injuries by participating in dynamic warm-up programs that include preventive exercises before games or during training sessions,and by adding strength,balance,and mobility training to the training sessions.

关键词： Balance Core stability Injury prevention programs Soccer Warm-up

Integration of physical and chemical treatment on the extraction of starch from Canna edulis Ker. rhizome

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Agricultural Sciences 2013年第9期4卷 51-55页

作者： Judy R. B. Witono Herry Santoso Y. I. P. Arry Miryanti Daniel Tan Chemical Engineering Department Parahyangan Catholic University Bandung Indonesia

The extraction ofCannaedulisKer. starch from its rhizome was performed using 2 different types of press (hydraulic press and screw press) and with the addition of Na-metabisulphite and NaOH (in the range of concentration 100 - 5000ppm each). The optimum condition for thisprocess was determined by Central Composite Design of experiment and the statistical calculation was solved by Design-Expert7.0.0. The targets of the observed responses were high starch yield, low ash, low fiber, and high carbohydrate content. The results showed that the starch yield and the reduction of fiber were only influenced by the physical treatment whereas ash content in the product was influenced byboth the NaOH concentration and physical treatment. The carbohydrate content in the extraction product was affected by NaOH, by the interaction between the concentrations of NaOH and Na2S2O5 and also by the physical treatment. The hydraulic press gives much better responses compared to the screw *** in the selected range of additives concentrations,the screw press gives a higher starch yield(30%-52%).

关键词： Canna edulis Ker. Central Composite Design of Experiment Hydraulic Press Screw Press Starch Extraction

Microenvironmental regulation of stem cells injected in the area at risk of neurodegenerative diseases

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BIOCELL 2022年第10期46卷 2231-2234页

作者： JU HYUNG LEE IL-KWON KIM SANG WOO KIM SOYEON LIM SEAHYOUNG LEE KI-CHUL HWANG BYEONG-WOOK SONG Graduate Program of Biomedical Engineering Yonsei UniversitySeoul03722Korea Institute for Bio-Medical Convergence College of MedicineCatholic Kwandong UniversityGangwon-do25601Korea Department for Medical Science College of MedicineCatholic Kwandong UniversityGangwon-do25601Korea

The complex mechanism of degenerative diseases and the non-specific modulation of regenerative targets aretopics that need to be elucidated in order to advance the use of stem cells in improvement of neurodegenerative *** pre-transplantation through post-transplantation, there are many changes in the conditions, both inside andoutside of the stem cells that have not been carefully considered. This has hindered development in the field of celltherapy and regeneration. This viewpoint highlights the potential implications of intracellular and extracellularalterations of stem cells in transplanted areas at risk of neurodegenerative disease.

关键词： Cell therapy Microenvironment Neurodegenerative disease Stem cells

Congenital retinal macrovessel with intracranial venous malformation in a pediatric patient: a case report

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International Journal of Ophthalmology(English edition) 2022年第7期15卷 1214-1216页

作者： Hyeon Jin Park Sook Hyun Yoon Sook Young Kim Donghun Lee Department of Ophthalmology Daegu Catholic University School of MedicineDaegu 42472Republic of Korea

Dear Editor,Congenital retinal macrovessel (CRM) is defined as an abnormal large retinal vessel that encircles the foveal avascular zone (FAZ).Since the first description of a large aberrant vessel crossing the macula by Mauthnerin 1868,there have been several case reports about *** recently,Pichi et alreported clinical manifestations and multimodal retinal imaging of 49 eyes with *** their study,they had identified an association between macrovessel in the retina and venous anomalies of the brain and they emphasized the importance of systemic workups including brain magnetic resonance imaging (MRI).

关键词： venous Congenital malformation

PNN-SVM Approach of Ti-Based Powder’s Properties Evaluation for Biomedical Implants Production

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Computers, Materials & Continua 2022年第6期71卷 5933-5947页

作者： Ivan Izonin Roman Tkachenko Michal Gregus Zoia Duriagina Nataliya Shakhovska Lviv Polytechnic National university Lviv79013Ukraine Comenius university in Bratislava Bratislava82005Slovak Republic The John Paul II catholic university of Lublin Lublin20-708Poland

The advent of additive technologies has provided a significant breakthrough in the production of medical *** has reduced costs,increased productivity and accuracy of the implant manufacturing ***,there are problems associated with assessing defects in the microstructure,mechanical and technological properties of alloys,both during their production by powder metallurgy and in the process of 3D *** traditional research methods of alloys properties demand considerable human,material,and time *** the same time,artificial intelligence tools create opportunities for intelligent evaluation of the conformity for the microstructure,phase composition,and properties of titanium powder’s *** provides new possibilities for the efficient production of biocompatible implants for various functional ***,the accuracy of the methods and models used should be as high as *** this paper we designed a hybrid PNN-SVM(Probabilistic Neural Network-Support Vector Machine)high-precision approach for the intelligent evaluation of alloy properties for additive manufacturing of biomedical *** have proposed a new approach for extending the dimensionality of input data space by the outputs of the summation layer of the modified PNN *** classification based on the expanded dataset is performed using *** conducted experimental modeling of the proposed approach using a data set on the properties of titanium alloys Ti-6Al-4V and *** have demonstrated a significant increase in the accuracy of the PNN-SVM scheme compared to the single classifiers that form it and other machine learning methods.

关键词： PNN SVM hybrid systems classification accuracy medical implants additive manufacturing 3D printing titanium alloys

Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma:Case series report

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World Journal of Clinical Cases 2022年第27期10卷 9693-9702页

作者： Heekyoung Song Jung Hwan Ahn Yuyeon Jung Jae Yeon Woo Jimin Cha Yang-Guk Chung Keun Ho Lee Department of Obstetrics and Gynecology Incheon St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Obstetrics and Gynecology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Orthopaedic Surgery Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Retroperitoneal sarcoma(RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor *** several studies have assessed the survival benefits of wide excision,few have reported detailed methods for achieving wide excision in patients with *** To describe our experience with multidisciplinary surgical resection of RPS using intra-and extra-pelvic *** Multidisciplinary surgery is an anatomical approach that combines intra-and extra-peritoneal access within the same surgery to achieve complete RPS *** retrospective review of the records of patients who underwent multidisciplinary surgery for RPS analyzed surgical and survival *** Eight patients underwent 10 intra-and extra-pelvic surgical resections,and their median mass size was 12.75 cm(range,6-45.5 cm).Using an intrapelvic approach,laparoscopy-assisted surgery was performed in four cases and laparotomy surgery in *** an extrapelvic approach,ilioinguinal and posterior approaches were used in four cases each,and the prone position and midline skin incision were shared in *** patients’ RPS masses were removed completely,and four achieved R0 resection through intra-and extra-pelvic *** median estimated blood loss was 2000 m L(range,300-20000 m L) and the median hospitalization was 12.6 d(range,9-69 d).Reoperation was needed in two patients(one for wound necrosis and the other for bowel perforation and wound necrosis).The median overall survival rate and median progression-free survival were 64.6 and 13.7 mo,*** RPS is therapeutically challenging because of its location and high risk of ***,intra-and extra-pelvic surgical approaches can improve the macroscopic security of the surgical margin.

关键词： Margins of excision Retroperitoneal neoplasms Sarcoma

Effect of ulinastatin on the inflammatory response after video-assisted thoracic lobectomy in patients with lung cancer:a randomized controlled study

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Chinese Medical Journal 2022年第7期135卷 806-812页

作者： Won Jung Hwang Min A.Joo Jin Joo Department of Anesthesiology and Pain Medicine Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulRepublic of Korea

Background:The first-line treatment for lung cancer is surgical resection,and one-lung ventilation(OLV)is the most basic anesthetic management method in lung *** OLV,inflammatory cytokines are released in response to the lung tissue damage and promote local and contralateral lung damage through the systemic *** designed a randomized,prospective study to evaluate the effect of the urinary trypsin inhibitor(UTI)ulinastatin on the inflammatory response after video-assisted thoracic lobectomy in patients with lung ***:Adult patients aged 19 to 70 years,who were scheduled for video-assisted thoracic lobectomy surgery to treat lung cancer between May 2020 and August 2020,were enrolled in this randomized,prospective ***(300,000 units)mixed with 100 mL of normal saline in the ulinastatin group and 100 mL of normal saline in the control group was administered over 1 h after inducing ***:The baseline(T0)interferon-γ(IFN-γ)/interleukin-4(IL-4)ratio was not different between the groups(6941.3±2778.7vs.6954.3±2752.4 pg/mL,respectively;P>0.05).The IFN-γ/IL-4 ratio was significantly higher in ulinastatin group at 30 min after entering the recovery room than control group(20,148.2±5054.3vs.6674.0±2963.6,respectively;adjustedP<0.017).Conclusion:Administering UTI attenuated the anti-inflammatory response,in terms of INF-γexpression and the IFN-γ/IL-4 ratio,after video-assisted thoracic surgery in lung cancer *** registration:Clinical Research Information Service of Korea National Institute of Health(CRIS),KCT0005533.

关键词： Ulinastatin Lung cancer Video-assisted thoracic surgery INF-γ IL-4

Preventing Health Anxiety:The Role of Self-Evaluation,Sense of Coherence,Self-Rated Health and Perceived Social Support

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International Journal of Mental Health Promotion 2023年第10期25卷 1081-1088页

作者： Sándor Csibi Mónika Csibi József Bognár Department of Sport Sciences Eszterházy Károly Catholic UniversityEger3300Hungary Department of Special Needs Education Eszterházy Károly Catholic UniversityEger3300Hungary

Background:Components of Self,completed with the perceived social support determine the individual differences in theevaluation of a stressor and the behavioral responses toward it,such as health-related *** study set as a goal theanalysis of associations between the components of Self,such as self-evaluation,sense of coherence,perceived social support,and reported health-related anxiety in an adult ***:147 adults from the 18–73 age group(mean age 37.5)voluntarily completed the questionnaire through Qualtrics online platform containing the Short Health Anxiety Inventory,Core Self-Evaluation Scale,Social Support Assessing Scale,and one Health Self-Evaluation ***:ANOVA foundrelevant differences in total scores and subscales’scores of the health anxiety scale depending on the positive *** regression shows that the analyzed variables were responsible for the prediction of a higher value on the“Perceivedprobability of becoming ill”subscale in a proportion of 45.6%and for the“Perceived consequence of illness”subscale in aproportion of 20.2%The predictive value of the linear regression model for the total score on the health anxiety scale was46.3%.Our findings show that negative Core Self-Evaluation is linked with perceived health ***:Selfevaluation,sense of coherence and perceived social support influence the perceived health and can explain the differences inthe reported health-related anxiety.

关键词： Core self-evaluation health anxiety health self-evaluation perceived social support self-concept the sense of coherence