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Laser speckle contrast imaging to predict the effect of temporary spinal cord stimulation in postherpetic neuralgia patients: A prospective observational study

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Journal of Innovative Optical Health Sciences 2024年第1期17卷 69-75页

作者： Xiang Huang Dacheng Tang Pan Chen Lumiao Chen Xiaohong Li Xiaoping Wang Department of pain management The First A±liated Hospital Jinan University Guang ZhouGuangdong 510630P.R.China Department of pain management The First People's Hospital of Foshan Foshan City Guangdong 528000P.R.China

Temporary spinal cord stimulation(tSCS)can effectively reduce the pain and severity of postherpetic neuralgia(PHN).However,there are no effective and objective methods for predicting the effects of tSCS on *** speckle contrast imaging(LSCI)is frequently used in neurology to evaluate the effectiveness of *** assess the accuracy of LSCI in predicting the impact of tSCS on PHN,14 adult patients receiving tSCS treatments for spinal nerve-innervated(C6-T2)PHN participated in this observational *** analog scale(VAS)assessments and LSCI bloodflow images of the-ngers were recorded after the tSCS *** results showed that the VAS scores of all patients decreased ***,the bloodflow index(BFI)values were signi-cantly higher than they were before the *** bloodflow and pain alleviation were positively ***-ndings indicated that spinal nerve PHN(C6-T2)was signi-cantly reduced by *** alleviation by tSCS was positively correlated with increased bloodflow in the *** effect of tSCS on PHN may thus be predicted using an independent and consistent indicator such as LSCI.

关键词： Laser speckle contrast imaging temporary spinal cord stimulation postherpetic neuralgia

Complex Regional pain Syndrome: Outpatient pain management in the Chronic Setting: A Case Report

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Open Journal of Anesthesiology 2024年第5期14卷 137-144页

作者： Julie Chege Ngugi Kinyungu ITAV pain management Medical School University of Nairobi New York USA ITAV pain management Donald and Barbara Zucker School of Medicine at Hofstra/Northwell New York USA

Background: Complex Regional pain Syndrome (CRPS), previously known as reflex sympathetic dystrophy and causalgia, is a neuropathic pain condition that usually develops after an injury to an extremity. CRPS can be a debilitating condition with high levels of pain and reduced function. Aim: This case report aims to discuss the multimodal approach in the management of a patient who presented with ongoing poorly controlled pain secondary to CRPS from an injury that happened years prior. Case Presentation: A 45-year-old female was involved in a motor vehicle accident where her right leg was injured. She underwent several surgeries and developed CRPS that significantly reduced her mobility and quality of life. She presented to the pain clinic years after her initial injury and a multimodal regimen was started for her resulting in significantly improved function. Conclusion: CRPS can be a severely debilitating condition. While early diagnosis and management are important, ongoing management in the outpatient chronic pain setting is important in maintaining a good level of function.

关键词： Chronic Regional pain Syndrome (CRPS) Multimodal management Chronic pain Sequelae

Thoracic spinal cord injury and paraplegia caused by intradural cement leakage after percutaneous kyphoplasty: A case report

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World Journal of Clinical Cases 2024年第10期12卷 1837-1843页

作者： Zi Mao Zhi-Hong Xiong Jun-Feng Li Department of pain management The Affiliated Hospital of Yunnan UniversityKunming 650000Yunnan ProvinceChina Department of Medical Administration The Affiliated Hospital of Yunnan UniversityKunming 650000Yunnan ProvinceChina

BACKGROUND Percutaneous kyphoplasty(PKP)is a pivotal intervention for osteoporotic fractures,pathological vertebral compression fractures,and vertebral bone *** its efficacy,the procedure presents challenges,notably complications arising from intradural cement *** and accurate diagnosis,coupled with emergent intervention is imperative to improve patient *** case report illuminates the intricacies and potential complications associated with PKP,emphasizing the critical need for vigilant monitoring,prompt diagnosis,and immediate intervention to mitigate adverse *** SUMMARY A 58-year-old male patient,experiencing a T7 osteoporosis-related pathological compression fracture,underwent PKP at a local *** weeks postprocedure,the patient developed paraplegic and dysuric symptoms,necessitating emergency decompression *** improvement was achieved,marked by the restoration of muscle strength,sensation,and *** PKP Intradural cement leakage following PKP is unusual and potentially *** imaging examinations,urgent evaluation,and the decompression surgery are essential,which help alleviate symptoms associated with spinal damage,markedly improving the overall prognosis.

关键词： Percutaneous kyphoplasty Intradural cement leakage Complication Decompression surgery Case report

Role of knowledge economy in managing demand-based environmental Kuznets Curve

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Geoscience Frontiers 2024年第4期15卷 397-410页

作者： Rukhsana Kalim Shajara Ul-Durar Mubasher Iqbal Noman Arshed Muhammad Shahbaz Department of Economics and Statistics Dr.Hassan Murad School of ManagementUniversity of Management and TechnologyLahorePakistan University of Sunderland The School of Business ManagementEdinburgh BuildingChester RoadSunderland SR13SDUnited Kingdom Department of Economics Division of Management and Administrative SciencesUniversity of EducationLahorePakistan Department of International Trade and Finance School of Management and EconomicsBeijing Institute of TechnologyBeijingChina Center for Sustainable Energy and Economic Development Gulf University for Science and TechnologyHawallyKuwait

Aggregate demand or supply at equilibrium is commonly used as a representative of the macroeconomic activity of an economy whereby aggregate demand denotes the behaviour of individuals and ***,aggregate demand can also directly affect environmental deterioration via changes in aggregate *** study tried to explore this relationship,known as the demand-based Environmental Kuznets Curve(Demand EKC)and the role of different knowledge economy *** economy indicators are proposed to influence consumption patterns,altering the demand EKC that empirical studies have *** this purpose,secondary data for 147 countries were collected from 2008 to 2018,also classified as *** study found that aggregate demand significantly affects carbon *** long-run results are estimated using the Fully Modified Ordinary Least Square *** factors like renewable energy consumption,population density,and financial development significantly affect carbon emissions in sample *** study has incorporated four pillars of a knowledge-based economy and the results showed that these indicators helped reduce consumption-related CO_(2) emissions.

关键词： Kuznets Curve Knowledge economy Higher education Institutional quality Innovation Technology

Association of the immediate perioperative dynamics of circulating DNA levels and neutrophil extracellular traps formation in cancer patients

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Precision Clinical Medicine 2024年第2期7卷 93-108页

作者： Andrei Kudriavtsev Brice Pastor Alexia Mirandola Ekaterina Pisareva Yann Gricourt Xavier Capdevila Alain R.Thierry Philippe Cuvillon Institut de Recherche en Cancerologie de Montpellier INSERM U1194Universite de MontpellierMontpellier 34298France Institut regional du Cancer de Montpellier Montpellier 34298France Department of Anaesthesiology and pain management Centre Hospitalo-Universitaire(CHU)CaremeauPlace du Professeur DebreNimes 30400France University of Montpellier Montpellier 34298France division of Anaesthesia Intensive Care Pain and Emergency MedicineMontpellier University HospitalMontpellier 34090France Montpellier NeuroSciences Institute INSERMU1298University of MontpellierMontpellier 34295Franc

Objectives:Elevated circulating DNA(cirDNA)concentrations were found to be associated with trauma or tissue damage which suggests involvement of inflammation or cell death in post-operative cirDNA *** carried out the first prospective,multicenter study of the dynamics of cirDNA and neutrophil extracellular trap(NETs)markers during the perioperative period from 24 h before surgery up to 72 h after curative surgery in cancer ***:We examined the plasma levels of two NETs protein markers[myeloperoxidase(MPO)and neutrophil elastase(NE)],as well as levels of cirDNA of nuclear(cir-nDNA)and mitochondrial(cir-mtDNA)origin in 29 colon,prostate,and breast cancer patients and in 114 healthy individuals(HI).Results:The synergistic analytical information provided by these markers revealed that:(i)NETs formation contributes to post-surgery conditions;(i)post-surgery cir-nDNA levels were highly associated with NE and MPO in colon cancer[r=0.60(P<0.001)and r=0.53(P<0.01),respectivelyl,but not in prostate and breast cancer;(i)each tumor type shows a specific pattern of cir-nDNA and NETs marker dynamics,but overall the pre-and post-surgery median values of cir-nDNA,NE,and MPO were significantly higher in cancer patients than in ***:Taken as a whole,our work reveals the association of NETs formation with the elevated cir-nDNA release during a cancer patient's perioperative period,depending on surgical procedure or cancer *** contrast,cir-mtDNA is poorly associated with NETs formation in the studied perioperative period,which would appear to indicate a different mechanism of release or suggest mitochondrial dysfunction.

关键词： circulating DNA perioperative period neutrophil extracellular traps neutrophil elastase myeloperoxidase minimal residualdisease

New insights into spexin and pituitary adenylate cyclase-activating polypeptide(PACAP)in regulating fish reproduction

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Aquaculture and Fisheries 2024年第3期9卷 411-416页

作者： Ashis Saha Mrinal Samanta Hirak kumar Barman Shiba Shankar Giri division of Fish Nutrition and Physiology ICAR-Central Institute of Freshwater AquacultureKausalyagangaBhubaneswarOdisha751002India division of Fish Health management ICAR-Central Institute of Freshwater AquacultureKausalyagangaBhubaneswarOdisha751002India division of Fish Genetics and Biotechnology ICAR-Central Institute of Freshwater AquacultureKausalyagangaBhubaneswarOdisha751002India

Reproduction is one of the most crucial physiological processes for the continuation of the generation of any *** are one of the most divergent aquatic *** reproductive neuro-endocrine regulatory studies are limited to only few *** regulation is a finely tuned complex mechanistic pathways,involving mainly hypothalamic-pituitary-gonad(HPG)*** the HPG axis,gonadotropin-releasing hormone(GnRH)modulates the synthesis and release of pituitary gonadotropins,which act on the gonads to stimulate steroidogenesis and *** recently,several novel neuropeptides,associated with reproductive regulation,have been ***(SPX),a novel neuropeptide coevolved with the galanin/kisspeptin family,has been identified as a regulator of the species-specific reproductive processes in *** adenylate cyclase-activating polypeptide(PACAP)is another novel member of the secretin-glucagon peptide family that functions as a hypophysiotropic factor involved in regulating pituitary hormone secretion in *** two emerging neuropeptides have pleiotropic functions,but information regarding their exact roles in fish reproduction is very *** updated overview of the mechanistic reproductive functions of these two new neuropeptides are highlighted in this review.

关键词： insight continuation exact

Increasing phosphorus fertilizer value of recycled iron phosphates by prolonged flooding and organic matter addition

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Pedosphere 2024年第3期34卷 631-640页

作者： Rochelle Joie SARACANLAO Hannah VAN RYCKEL Mieke VERBEECK Maarten EVERAERT Erik SMOLDERS division of Soil and Water management Department of Earth and Environmental ScienceKU LeuvenKasteelpark Arenberg 20Heverlee B-3001(Belgium) Soil Service of Belgium.Willem De Croylaan 48 Leuven 3001(Belgium)

Iron(Fe)minerals are commonly used to remove phosphorus(P)from waste streams,producing P-loaded Fe(Ⅲ)oxides or Fe(Ⅱ)phosphate minerals(e.g.,vivianite).These minerals may be used as fertilizers to enhance P circularity if solubilized in ***,we tested the P fertilizer value of recycled Fe phosphates(FePs)in a pot trial and in an incubation experiment,hypothesizing that P release from FePs is possible under Fe(Ⅲ)-reducing ***,a pot trial was set up with rice(Oryza sativa)in all combinations of soil flooding or not,three P-deficient soils(acid,neutral,and calcareous),and six FePs(three Fe(Ⅲ)Ps and three Fe(Ⅱ)Ps)referenced to triple superphosphate(TSP)or zero *** P uptake responded to TSP application in all treatments but only marginally to *** redox potential did not decrease to-200 mV by flooding for a brief period(13 d)during the pot trial.A longer incubation experiment(60 d)was performed,including a treatment of glutamate addition to stimulate reductive conditions,and P availability was assessed with CaCl_(2)extraction of *** addition and/or longer incubation lowered soil redox potential to<-100 *** the longer term,Fe(Ⅲ)minerals released P,and adequate P was reached in the calcareous soil and in the neutral soil amended with Fe(Ⅲ)*** can be concluded that prolonged soil flooding and organic matter addition can enhance the P fertilizer efficiency of ***,application of FeP in powder form may enhance P availability.

关键词： agronomic efficiency circular economy P-loaded Fe(Ⅲ)oxides paddy soil vivianite redox

Development of international guidelines by Tuina practitioners for specific acupoints of paediatrics Tuina(2022 version)

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Journal of Traditional Chinese Medicine 2024年第5期44卷 1044-1051页

作者： LAN Xiaoxue SUN Yanan WENG Zhiwen WANG Yue ZHANG Ying LIANG Yuanwen GU Sirui ZHOU Rong CHEN Qianji JIA Baolin BO Han WANG Fangying HE Qiang ZHANG Jie TAN Jiang YE Xingzhu WANG Xiyou YU Changhe CHEN Hong Department of Tuina and pain management the First Clinical DepartmentBeijing University of Chinese Medicine Department of Traditional Chinese Medicine Xuanwu HospitalCapital Medical University Department of Tuina and pain management Dongzhimen Hospital of Beijing University of Chinese Medicine Department of Encephalopathy Beijing Huairou Hospital of Traditional Chinese Medicine Yungang Community Health Service Center China Aerospace Science & Industry Corporation of 731 Hospital Department of Pediatrics China-Japan Friendship Clinical SchoolBeijing University of Chinese Medicine Department of Pediatrics the Second Clinical Medical College of Beijing University of Chinese Medicine Shenzhen Luohu Hospital of Traditional Chinese Medicine Department of Chinese Medicine Raffles Medical Group Department of Traditional Chinese Medicine Beiing Children's HospitalCapital Medicine UniversityNational Center for Children's Health Anzhen Community Health Service Center L. Ac. Ancient Healing Center Frederick Department of Tuina and pain management Dongzhimen HospitalBeijing University of Chinese Medicine

OBJECTIVE: To establish a standardized framework encompassing the precise locations, manipulations,functions and indications of specific acupoints in the field of paediatric Tuina. METHODS: The development of consensus involved three distinct stages. Initially, a list of paediatric Tuina specific acupoints was compiled based on an extensive literature review, which was subsequently supplemented through expert interviews. In the second stage, the Delphi method was employed to assess the significance of acupoint locations, manipulations, functions, and indications. In situations where the questionnaire survey failed to yield agreement or when the experts held reservations, the nominal group approach was utilized during the expert consensus meeting. The final version of the technical standardized material was ultimately determined during an expert consensus conference. After undergoing external peer review and evaluation, the completed draft was prepared for public dissemination RESULTS: The comprehensive list identified a total of 66 specific acupoints. The location and manipulation questionnaire consisted of 156 items based on the literature database, while the function and indication questionnaire contained 116 items. Two rounds of Delphi surveys were conducted for the location and manipulation category, and another two rounds of Delphi surveys were conducted for the function and indication category. During the experts consensus meeting The panel of experts conducted in-depth discussions on 61 questions, resulting in the formulation of technical guidelines for the locations, manipulations, functions, and indications of 64 paediatric Tuina acupoints. Subsequently, the research team compiled and edited the draft of the technical guidelines for acupoints of paediatric Tuina, which was finalized after external review and feedback. CONCLUSION: This study successfully established the recognized technical standards for practitioners of paediatric Tuina, thereby standardizi

关键词： Child Delphi technique Tuina acupoint guideline international paediatrics

Ultrasound-Guided Superior Gluteal Nerve Hydrodissection in the Treatment of Deep Gluteal Syndrome

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pain Studies and Treatment 2024年第3期12卷 49-53页

作者： Janai Puckett Roisin Hosie Dominic Harmon Medical School University of Limerick Limerick Ireland pain management Centre University Hospital Limerick Limerick Ireland

Background: Deep gluteal syndrome is a common cause of posterior hip pain. It results from peripheral nerves, such as the sciatic or superior gluteal nerve, being compressed in the deep gluteal space. Hydrodissection is a novel technique for the treatment of nerve pain due to entrapment. The use of hydrodissection for the treatment of deep gluteal syndrome has not been reported. Methods: A case report involved a 42-year-old female presenting with deep gluteal syndrome. Case report: We report, with patient consent, an ultrasound-guided superior gluteal nerve hydrodissection method used for treating the deep gluteal syndrome. A previously healthy 42-year-old female patient sought medical attention due to persistent left gluteal pain. Trials of joint injections, physiotherapy, and epidural blocks were unsuccessful. Hydrodissection under ultrasound-guidance allowed separation of the fascial plane in areas with significant neural innervation. We targeted the superior gluteal nerve with hydrodissection offering the patient immediate and persistent relief from her symptoms. Conclusion: Ultrasound-guided hydrodissection of the superior gluteal nerve offers an effective and novel diagnostic and treatment option for deep gluteal syndrome.

关键词： Superior Gluteal Nerve Deep Gluteal Syndrome Lower Limb Radicular pain Deep Gluteal Space Hydrodissection Ultrasound