检索结果-南通市图书馆

The impact of female sex hormones on cardiovascular disease:from mechanisms to hormone therapy

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2024年第6期21卷 669-681页

作者： Yi KAN Yu-Lu PENG Ze-Hao ZHAO Shu-Tong DONG Yin-Xiao XU Xiao-Teng MA Xiao-Li LIU Yu-Yang LIU Yu-Jie ZHOU Department of Cardiology Beijing Anzhen HospitalCapital Medical UniversityBeijing Institute of Heart Lung and Blood Vessel DiseaseBeijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic DiseaseClinical Center for Coronary Heart DiseaseCapital Medical UniversityBeijingChina

Cardiovascular disease remains the leading cause of mortality in women,yet it has not raised the awareness from the *** pathogenesis of cardiovascular disease differs significantly between females and males concerning the effect of sex *** and progestogen impact cardiovascular system through genomic and non-genomic *** menopause,cardiovascular protective effects of estrogens have been well *** were often used in combination with estrogens in hormone *** in sex hormone levels,particularly estrogen deficiency,were considered the specific risk factor in women’s cardiovascular ***,considerable heterogeneity in the impact of hormone therapy was observed in clinical *** heterogeneity is likely closely associated with factors such as the initial time,administration route,dosage,and formulation of hormone *** review will delve into the pathogenesis and hormone therapy,summarizing the effect of female sex hormones on hypertension,pre-eclampsia,coronary heart disease,heart failure with preserved ejection fraction,and cardiovascular risk factors specific to women.

关键词： impact dosage protective

Effects of PEAR1 gene polymorphism on big endothelin-1 levels in Chinese patients with acute myocardial infarction after percutaneous coronary intervention

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2024年第3期15卷 229-231页

作者： Yi Yao Na Xu Xiaofang Tang Ce Zhang Sida Jia Jingjing Xu Ying Song Xueyan Zhao Runlin Gao Jinqing Yuan Center for coronary Heart Disease National Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseFuwai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China

Acute myocardial infarction (AMI) has been associated with poor prognosis,even after revascularization with percutaneous coronary intervention (PCI),likely due to coronary endothelial cell dysfunction and injury.^([1,2])Endothelin-1 (ET-1),a peptide that serves as a vasoconstrictor of smooth muscle cell proliferation,can reflect endothelial cell functional *** to low circulation levels and short plasma half-life time,measuring plasma ET-1 levels is *** contrast,big ET-1.

关键词： coronary percutaneous endothelin

Updates of developments in interventional therapy for elderly patients with cardiovascular diseases

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2024年第1期21卷 1-3页

作者： Hua SHEN Xun-Xun FENG Qian-Yun GUO Yu-Jie ZHOU Beijing Key Laboratory of Precision Medicine of coronary Atherosclerotic Disease Beijing Institute of Heart Lung and Blood Vessel DiseaseClinical Center for Coronary Heart DiseaseDepartment of CardiologyBeijing Anzhen HospitalCapital Medical UniversityBeijingChina

Cardiovascular diseases(CVD)are the leading cause of death in the world and one of the most common diseases in the elderly,with high prevalence and poor prognosis,which seriously affect the health of the elder *** report showed that global deaths from CVD increased from 12.4 million in 1990 to 19.8 million in 2022,reflecting the global population growth and aging,as well as the impact of metabolic,environmental,and behavioral risks.[1]With the progress of aging population,the burden of CVD in the elderly in China has increased year by year,and factors including multiple complications,organ function decline,and high complication rate have made the interventional treatment of CVD in the elderly one of the difficulties and focuses in the field of cardiology in China.

关键词： diseases patients prognosis

Risk analysis of gastrointestinal bleeding in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

在线全文

学校读者我要写书评

暂无评论

China Medical Abstracts(Internal Medicine) 2024年第1期41卷 35-36页

作者：叶明 coronary Artery Dis Center Div CardiolBeijing Anzhen HospCapital Med UnivBeijing 100029

Objective To investigate the in-hospital incidence,associated outcomes,and predictors of UGIB after *** In this retrospective study,we analyzed the records of 2 791 patients with acute STEMI admitted to Beijing Anzhen... 详细信息

关键词： admitted patients acute

Gut microbiome regulates inflammation and insulin resistance:a novel therapeutic target to improve insulin sensitivity

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第3期9卷 825-827页

作者： Dilvin Semo Holger Reinecke Rinesh Godfrey Vascular Signalling Molecular CardiologyDepartment of Cardiology I-Coronary and Peripheral Vascular DiseaseHeart FailureUniversity Hospital Münster48149 MünsterGermany

In a recent study published in Nature,Takeuchi et *** a multiomics strategy in humans to provide compelling evidence that increased carbohydrate metabolism by the gut microbiota contributes to insulin resistance(IR).The authors uncovered a previously unknown link between elevated gut monosaccharides and host inflammatory cytokines and suggest potential intervention opportunities to combat IR by targeting specific gut microbial species.

关键词： metabolism inflammation al.

Effects of dual antiplatelet therapy de-escalation on the prognosis of acute coronary syndrome patients at high risk of ischemia who underwent percutaneous coronary intervention

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2024年第6期137卷 746-748页

作者： Jingyao Wang Yachao Li Mengjie Lei Yanli Yang Haiyan Gao Xiangjin Wang Lei An Haili Zhou Xue Sun Cairong Li Zhigang Zhao Zengming Xue Department of Cardiology Langfang People’s HospitalHebei Medical UniversityLangfang Core Laboratory of Precision Treatment of Coronary Artery DiseaseLangfangHebei 065000China

To the Editor:Current guidelines recommend that for patients with acute coronary syndrome(ACS)undergoing percutaneous coronary intervention(PCI),dual antiplatelet therapy(DAPT),preferably involving powerful P2Y_(12) receptor inhibitors,including ticagrelor or prasugrel,should be used for at least 12 months.^([1–3])However,there is a lack of relevant evidence regarding the feasibility of de-escalation treatment and specific DAPT treatment regimens for ACS patient populations with high ischemic risk.

关键词： coronary patients acute

Thrombolysis in elderly patients

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2007年第4期4卷 250-253页

作者： Santiago Herrero Jose Antonio Lapuerta-Irigoyen pacemaker and coronary unit Intensive Care ServiceCabuees HospitalGijon Spain pacemaker and coronary unit Intensive Care ServiceCabuees HospitalGijonSpain

The elderly population consists of those over age 75 years and appears to represent the fastest-growing segment of the population. Intravenous thrombolytic therapy (TT) is the most common strategy for the treatment of acute myocardial infarction (AMI) in many parts of the world. However, TT carries a higher risk of intra-cranial hemorrhage (ICH) in the elderly patients. Primary percutaneous transluminal coronary angioplasty and stenting (PCI) represents an important alternative in these elderly individuals with contraindications to TT. In developing countries, or in areas without availability of primary PCI, TT remains the only therapeutic modality. Dedicated randomized trials are needed to provide a comprehensive understanding of AMI management in the elderly group.(J Geriatr Cardiol 2007;4:250-253.)

关键词： acute myocardial infarction thrombolysis elderly

The Efficacy and Safety of Drug-Coated Balloons in the Treatment of Acute Myocardial Infarction

在线全文

学校读者我要写书评

暂无评论

World Journal of Cardiovascular Diseases 2024年第1期14卷 1-9页

作者： Mingliang Du Hui Hui Department of coronary Heart Disease Dalian Municipal Central Hospital Dalian China

The incidence of acute myocardial infarction (AMI) is increasing year by year, which seriously endangers human health around the world. The preferred treatment strategy for AMI patients is the use of drug-eluting stents (DES), as there is ample evidence to suggest that stent implantation can reduce major adverse cardiovascular events (MACEs). With the application of drug-coated balloons (DCBs) and the enhancement of the concept of interventional without implantation, the question is whether DCBs can be safely and effectively used in patients with AMI? The purpose of this study was to investigate the safety and effectiveness of DCBs in the treatment of AMI. A retrospective review of clinical data was conducted on 55 AMI patients who underwent primary percutaneous coronary intervention (PCI) from January 2020 to December 2021. Of these patients, 25 were treated with DCBs and 30 were treated with DESs. Optical coherence tomography (OCT) was used to measure the minimum lumen diameter, lumen stenosis, and coronary artery dissection before and after surgery, and angina pectoris attacks and various MACEs were recorded at 1, 6, and 12 months after surgery. The results showed that there were no significant differences in clinical baseline data between the two groups. However, the minimum lumen diameter of the DCB group immediately after the operation was smaller than that of the DES group, and the stenosis degree of the lumen in the DCB group was higher than that in the DES group. The incidence of coronary artery dissection in the DCB group was significantly higher than that in the DES group, but the majority of them were type B. At 1, 6, and 12 months after treatment, there was no significant difference in the occurrence of MACEs between the two groups. In conclusion, DCBs is a safe and effective treatment for AMI. However, the incidence of coronary artery dissection in DCB patients is higher than that in DES patients, but the majority of them are type B. .

关键词： Myocardial Infarction Drug-Coated Balloon Drug-Eluting Stents

pacemaker therapy in the elderly patients

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

老年心脏病学杂志：英文版 2007年第2期4卷 127-128页

作者： Jose Antonio Lapuerta-Irigoyen Santiago Herrero pacemaker and coronary unit Intensive Care Service Cabuees Hospital Gijon Spain

　　The treatment of choice in symptomatic cases of patients with severe bradycardia remains the implantation of a pacemaker.……

关键词： pacemaker therapy in the elderly patients