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Computer Modeling in Engineering & Sciences 2025年第1期142卷 501-530页

作者： Khuram Ali Khan Saba Mubeen Ishfaq Atiqe Ur Rahman Salwa El-Morsy department of mathematics University of SargodhaSargodha40100Pakistan department of mathematics University of Management and TechnologyLahore54000Pakistan department of mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia

Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be *** concept of a possibility pythagorean fuzzy hypersoft set(ppyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such *** study investigates the elementary notions of ppyFHSS including its set-theoretic operations union,intersection,complement,OR-and *** results related to these operations are also modified for ***,the similarity measures between ppyFHSSs are formulated with the assistance of numerical examples and ***,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested *** algorithmic results are compared with the most pertinent model to evaluate the adaptability of ppyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical ***,while considering significant evaluating factors,the flexibility of ppyFHSS is observed through structural comparison.

关键词： Hypersoft set pythagorean fuzzy hypersoft set computational complexity multi-attribute decision-making optimization similarity measures uncertainty

predicting Maximum Lifespan Limits at Mean Menopausal Age

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Journal of Mathematical research with Applications 2025年第1期 133-142页

作者： M.SUMATHI S.ANTONY CARLA department of mathematics N.M.S.S.Vellaichamy Nadar College research Scholar (part-time) Madurai Kamaraj University

The age at which a woman enters natural menopause has also been associated to death from any cause. Menopause is a natural component of aging that happens between the ages of 45 and 55, with the average menopausal age being 51. previous research has revealed the age at which women reach menopause, but there is no evidence to support the link between menopause and longevity. We made a study in assessing the limits of maximum lifespan at menopausal age in our previous article. In this paper, we aim to predict the maximum lifespan of women at mean menopausal age.

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Consequence of exponential heat generation on non-Darcy- Forchheimer flow of water based carbon nanotubes driven by a curved stretching sheet

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Applied mathematics and Mechanics(English Edition) 2020年第11期41卷 1723-1734页

作者： B.J.gIREESHA B.NAgARAJA S.SINDHU g.SOWMYA department of p.g.Studies and research in mathematics Kuvempu UniversityShankaraghatta 577451India

The present article comprises the study on the influence of exponential space based heat generation on the non-Darcy-Forchheimer flow of carbon nanotubes(CNTs).The flow is considered over a curved stretching *** variables are used to reduce the flow descriptive nonlinear partial derivative equations to simple *** equations are then solved by the exploiting Runge-Kutta-Fehlberg fourth-and fifth-order *** numerical solutions are shown in graphs and *** between single and multi-walled CNTs has been established through the tabulated values and plotted *** is concluded that the heat source parameter plays a prime role in enhancement of temperature,and the curvature parameter has adverse impact on velocity and temperature *** the inertial parameter and inverse-Darcy number affect the fluid velocity.

关键词： exponential heat generation non-Darcy-Forchheimer flow carbon nanotube(CNT) curved stretching sheet

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Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis

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Science China Life Sciences 2025年第1期 103-115页

作者： Xizi Luo Nan Zhang Yuntao Liu Beibei Du Xuan Wang Tianxu Zhao Bingqiang Liu Shishun Zhao Jiazhang Qiu guoqing Wang State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Basic MedicineJilin University State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Veterinary MedicineJilin University College of mathematics Jilin University Bioinformatic Lab School of MathematicsShandong University department of Cardiology China-Japan Union HospitalJilin University

The coronavirus disease 2019（COVID-19） outbreak caused by the severe acute respiratory syndrome coronavirus-2（SARS-CoV-2） developed into a global health emergency. Systemic microthrombus caused by SARS-CoV-2 infection is a common complication in patients with COVID-19. Cardiac microthrombosis as a complication of SARS-CoV-2 infection is the primary cause of cardiac injury and death in patietns with severe COVID-19. In this study, we performed single-cell sequencing analysis of the right ventricular free wall tissue from healthy donors,patients who died during the hypercoagulable period of characteristic coagulation abnormality（CAC）, and patients who died during the fibrinolytic period of CAC. We collected 61,187 cells enriched in 24 immune cell subsets and 13 cardiac-resident cell subsets. We found that in the course of SARS-CoV-2 infected heart microthrombus, MYO1EhighRASgEF1Bhighmonocyte-derived macrophages promoted hyperactivation of the immune system and initiated the extrinsic coagulation pathway by activating chemokines CCL3, CCL5. This series of events is the main cause of cardiac microthrombi following SARS-CoV-2 infection. In a SARS-CoV-2 infected heart microthrombus, excessive immune activation is accompanied by an increase in cellular iron content, which in turn promotes oxidative stress and intensifies intercellular competition. This induces cells to alter their metabolic environment, resulting in increased sugar uptake via the glycosaminoglycan synthesis pathway. In addition, high levels of reactive oxygen species generated by elevated iron levels promote increased endogenous malondialdehyde synthesis in a subpopulation of cardiac endothelial cells. This exacerbates endothelial cell dysfunction and exacerbates the coagulopathy process.

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Antibacterial activity of various leaf extracts of Merremia emarginata

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Asian pacific Journal of Tropical Biomedicine 2011年第5期1卷 406-408页

作者： EK Elumalai M Ramachandran T Thirumalai p Vinothkumar p.g.and research department of Zoology Physiology WingVoorhees College Bioinformatics Center Central Agricultural Research InstitutePort BlairAndaman & Nicobar p.g.and department of Microbiology Mohamed Sathak College of Arts and ScienceSholinganallur

Objective:To investigate the antibacterial activity and phytochemical screening of the *** and petroleum ether leaf extracts of Merremia emarginata(***).Methods:The antibavterial activity of leaf extracts of *** were evaluated by agar well diffusion method against four selected bacterial ***:The presence of tannins,flavonoids,amino acids,starch,glycosides and carbohydrates in the different leaf extracts was *** methanol extract was more effective against Baciilus cereus and Eseherkhia coli,whereas aqueous extract was more effective against Staphylococcus aureus and pseudomonas ***:The results in the present study suggest that *** leaf can be used in treating diseases caused by the tested organisms.

关键词： Merremia emarginata Methanol extract Aqueous extract

Solution for fractional potential KdV and Benjamin equations using the novel technique

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Journal of Ocean Engineering and Science 2021年第3期6卷 265-275页

作者： p.Veeresha D.g.prakasha N.Magesh A.John Christopher Deepak Umrao Sarwe department of mathematics CHRIST(Deemed to be University)Bengaluru-560029India department of mathematics Faculty of ScienceDavangere UniversityShivagangothriDavangere-577007India p.g.and research department of mathematics Govt.Arts College for MenKrishnagiri-635001India department of mathematics University of MumbaiKalinaSantacruz EastMumbai-400098India

In this paper,we find the solutions for fractional potential Korteweg-de Vries(p-KdV)and Benjamin equations using q-homotopy analysis transform method(q-HATM).The considered method is the mixture of q-homotopy analysis method and Laplace transform,and the Caputo fractional operator is considered in the present *** projected solution procedure manipulates and controls the obtained results in a large admissible ***,it offers a simple algorithm to adjust the convergence province of the obtained *** validate the q-HATM is accurate and reliable,the numerical simulations have been conducted for both equations and the outcomes are revealed through the plots and *** between the obtained solutions with the exact solutions exhibits that,the considered method is efficient and effective in solving nonlinear problems associated with science and technology.

关键词： potential KdV equation q-Homotopy analysis method Fractional Benjamin equation Laplace transform ginzburg-Landau equation Caputo fractional operator

Maximizing biomass utilization: An integrated strategy for coproducing multiple chemicals

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Journal of Energy Chemistry 2025年第1期100卷 180-191页

作者： Byeongchan Ahn Sua Jo Jonggeol Na J.Jay Liu Young-Ju Kim Wangyun Won department of Chemical and Biological Engineering Korea University department of Chemical Engineering (Integrated process) Kyung Hee University department of Chemical Engineering and Materials Science Ewha Womans University department of Chemical Engineering Pukyong National University Resources Engineering plant research department Korea Institute of Geoscience and Mineral Resources

Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol（1,6-HDO） with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments（LCAs）.Strategy A was found to be the most favorable both economically（USRDSCHARDOLLAR3,402/ton） and environmentally（-26.9 kg CO2eq.）. This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.

关键词： Biorefinery Carbon mitigation Climate change global warming Lignin utilization Bioeconomy

Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

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Neural Regeneration research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-Merz Jorge Hernández-Campano Sergei A.Kirov Jesús M.Hernández-guijo department of pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany department of Neuroscience and Regenerative Medicine&department of Neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system N transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through N-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

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Observational insights into the accelerating universe through reconstruction of the deceleration parameter

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Chinese physics C 2023年第8期47卷 184-194页

作者： Devaraja Mallesha Naik N.S.Kavya V.Venkatesha department of p.g.Studies and research in mathematics Kuvempu UniversityShankaraghattaShivamogga 577451KarnatakaINDIA

Recent developments in the exploration of the universe suggest that it is in an accelerated phase of ***,our study aims to probe the current scenario of the universe with the aid of the reconstruction *** primary factor that describes cosmic evolution is the deceleration ***,we provide a physically plausible,newly defined model-independent parametric form of the deceleration ***,we constrain the free parameters through statistical MCMC analysis for different datasets,including the most recent pantheon+.With the statistically obtained results,we analyze the dynamics of the model through the phase trans-ition,EoS parameter,and energy ***,we make use of the tool Om diagnostic to test our model.

关键词： deceleration parameter parametric reconstruction observational constraints accelerating universe Om diagnostics

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Hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rat

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Asian pacific Journal of Tropical Biomedicine 2011年第4期1卷 323-325页

作者： T Thirumalai S Viviyan Therasa EK Elumalai E David p.g.and research department of Zoology Voorhees CollegePhysiology wingVellore-632001(T.N.)India

Objective:To evaluate the hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino ***:Hypoglycemic activity of Brassica juncea(seeds)aqueous extract at a dose of 250,350 and 450 mg/kg body weight was *** male Swiss albino rats of six numbers in each group was undertaken for study and ***:The serum insulin levels were recorded a significant depletion in all groups,short term as well as long term diabetic animals,when compared to that of normal animals.A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term ***:The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat.

关键词： Hypoglycemic Diabetes mellitus Ayurveda Anti-diabetic Insulin