检索结果-南通市图书馆

第九届全国免疫学学术大会

作者： Yunan Zhu Yingfeng Wei Jianing Chen Guangying Cui Yulong Ding Masashi Kohanawa Hongyan Diao State Key Laboratory for diagnosis and Treatment of Infectious Diseases The First Affiliated HospitalSchool of MedicineZhejiang University Collaborative Innovation Center for diagnosis and Treatment of Infectious Diseases Department of Microbiology School of MedicineHokkaido University

Background:Osteopontin is increased in bacterial lung ***,the level of osteopontin in virus-induced lung injury patients is not clear and the relationship between the hyerproduction of osteopontin and lung injury remains to be throughly ***:This study aimed to determine whether there is any link between osteopontin and pulmonary damage,particularly,pulmonary edema and destruction of pulmonary ***:Patients infected with the H1N1 or H7N9 viruses were *** clinical data were collected and a series of immunological parameters were *** epithelial cells were used to determine the effects of OPN in terms on the expression of two mediators of lung injury:epithelial sodium channels(ENaC),which enable the clearance of pulmonary edema fluid,and matrix metalloproteinase 7(MMP7),which degrades components of the lung ***:OPN levels were significantly elevated in patients with pulmonary damage(22.15±2.87ng/ml in H7N9 patients vs 14.14±0.90ng/ml in H1N1 patients and 13.19±1.20ng/ml in healthy control,P<0.05,P<0.05),and serum OPN levels and disease severity in influenza lung injury were positively correlated(R=0.688,P<0.0001).OPN treatment increased the rate of apoptosis in lung epithelial cells in vitro,and markedly decreased the expression of the a-subunit of ENaC throughβ3 integrin and ***,the expression of MMP7 was promoted by the interaction of OPN with integrinβ1 and *** addition,the levels of tumor necrosis factor-α(106.00±11.85pg/ml vs 55.89±3.04pg/ml,P<0.05)and interleukin-6(75.17±2.59pg/ml vs 51.29±6.42pg/ml,P<0.05),important cytokines in acute lung injury,were increased by ***:These findings suggested that OPN may increase influenza virus-induced lung injury through enhancing lung epithelial cell apoptosis and extracellular matrix destruction,as well as impairing the function of epithelial cell sodium channels.

关键词： Osteopontin influenza A virus lung injury apoptosis epithelial sodium channel

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Evaluation of an oral moisture-checking device for screening dry mouth

引用

Open Journal of Stomatology 2013年第8期3卷 440-446页

作者： Yosuke Fukushima Tetsuya Yoda Shoichiro Kokabu Ryuichiro Araki Tsubasa Murata Yoshimasa Kitagawa Ken Omura Shuji Toya Kayoko Ito Saori Funayama Hiroshi Iwabuchi Kazuhiro Asano Yutaka Imai Akihide Negishi Satoshi Yokoo Goichi Matsumoto Eiro Kubota Hideki Watanabe Mikio Kusama Kojiro Onizawa Takuya Goto Seiji Nakamura Ryuichi Nakazawa Kiyoshi Harada Takashi Fujibayashi Community Health Science Center Saitama Medical University Saitama Japan Department of Dentistry and oral Surgery Tochigi National Hospital Tochigi Japan Department of oral and Maxillofacial Surgery Division of Medicine Interdisciplinary Graduate School of Medicine and Engi- neering Univer-sity of Yamanashi Kofu and Tamaho Japan Department of oral and Maxillofacial Surgery Dokkyo Medical University School of Medicine Tochigi Japan Department of oral and Maxillofacial Surgery Faculty of Medicine Sai-tama Medical University Saitama Japan Department of oral and Maxillofacial Surgery Institute of Clinical Medicine University of Tsukuba Tsukuba Japan Department of oral and Maxillofacial Surgery Jichi Medical University Tochigi Japan Department of oral and Maxillofacial Surgery Kanagawa Dental College Yokosuka Japan Department of Stomatology and oral Surgery Gunma University Graduate School of Medicine Maebashi Japan Division of Gereatric Dentistry Niigata University Medical & Dental Hospital Niigata Japan oral and Maxillofacial Surgery Dry Mouth Clinic The Nippon Dental University Niigata Hospital Niigata Japan oral diagnosis and medicine Department of Oral Pathobiological Science Graduate School of Dental Medicine Hokkaido University Sapporo Japan oral Surgery Department of Oral Restitution Division of Oral Health Sciences Graduate School Tokyo Medical and Dental University Tokyo Japan Section of oral and Maxillofacial Oncology Division of Maxillofacial Diagnostic and Surgical Sciences Faculty of Dental Science Kyushu University Fukuoka Japan

Objective: This multicenter clinical study was to assess the clinical usability of an oral moisture-checking device in detecting the dry mouth patients and evaluating the optimal measurement site. Materials and Methods: The study group comprised 250 patients with dry mouth and 241 healthy volunteer subjects at 13 medical centers. This device was used to measure the moisture degrees of the lingual mucosa and the buccal mucosa. Subjective oral dryness, objective oral dryness, and saliva flow rates were also compared between the two groups. For statistical analysis, receiver-operating characteristic analysis was performed to calculate the area under the curve (AUC). Results: The moisture degree of the lingual mucosa was significantly lower in the dry mouth group (27.2 ± 4.9) than that in the healthy group (29.5 ± 3.1, AUC = 0.653). When a lingual mucosa moisture degree of 31.0 or higher was defined as normal, less than 27.0 as dry mouth, and 27.0 to less than 31.0 as borderline zone of dry mouth, both the sensitivity and the specificity for the diagnosis of dry mouth were close to 80%. Conclusion: These results suggest that the oral moisture-checking device is a usable screening device for dry mouth.

关键词： Dry Mouth oral Moisture-Checking Device ROC Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Administration of modified Gegen Qinlian decoction for hemorrhagic chronic radiation proctitis: A case report and review of literature

引用

World Journal of Clinical Cases 2023年第5期11卷 1129-1136页

作者： Shao-Yong Liu Liu-Ling Hu Shi-Jun Wang Zhong-Li Liao Traditional Chinese medicine Cancer Treatment Center Chongqing University Cancer HospitalChongqing 400030China The Center for Gastroenterology Diagnosis and Minimally Invasive Treatment of Early Gastrointestinal CancerChongqing University Cancer HospitalChongqing 400030China

BACKGROUND Hemorrhagic chronic radiation proctitis(CRP) is a common late complication of irradiation of the pelvis and seriously impairs life quality. There is no standard treatment for hemorrhagic CRP. Medical treatment, interventional treatment, and surgery are available, but they are limited in their applications due to nondefinite efficacy or side effects. Chinese herbal medicine(CHM), as a complementary or alternative therapy, may provide another option for hemorrhagic CRP *** SUMMARY A 51-year-old woman with cervical cancer received intensity-modulated radiation therapy and brachytherapy with a total dose of 93 Gy fifteen days after hysterectomy and bilateral adnexectomy. She received six additional cycles of chemotherapy with carboplatin and paclitaxel. Nine months after radiotherapy treatment, she mainly complained of 5-6 times diarrhea daily and bloody purulent stools for over 10 d. After colonoscopy examinations, she was diagnosed with hemorrhagic CRP with a giant ulcer. After assessment, she received CHM treatment. The specific regimen was 150 mL of modified Gegen Qinlian decoction(GQD) used as a retention enema for 1 mo, followed by replacement with oral administration of 150 mL of modified GQD three times per day for 5 mo. After the whole treatment, her diarrhea reduced to 1-2 times a day. Her rectal tenesmus and mild pain in lower abdomen disappeared. Both colonoscopy and magnetic resonance imaging confirmed its significant improvement. During treatment,there were no side effects, such as liver and renal function *** Modified GQD may be another effective and safe option for hemorrhagic CRP patients with giant ulcers.

关键词： Hemorrhagic chronic radiation proctitis Chinese herbal medicine Gegen Qinlian decoction Retention enema Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling

引用

International Journal of oral Science 2023年第3期15卷 437-449页

作者： Tiancheng Li Han Wang Yukun Jiang Shuo Chen Danyuan Huang Zuping Wu Xing Yin Chenchen Zhou Yuyu Li Shujuan Zou State Key Laboratory of oral Diseases&National Center for Stomatology&National Clinical Research Center for oral Diseases&West China Hospital of Stomatology Sichuan UniversityChengduChina Department of Orthodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Center for StomatologyNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of StomatologyShanghai Research Institute of StomatologyShanghaiChina

Orthodontically induced tooth root resorption(OIRR)is a serious complication during orthodontic *** cementum repair is the fundamental approach for the treatment of *** hormone(PTH)might be a potential therapeutic agent for OIRR,but its effects still lack direct evidence,and the underlying mechanisms remain *** study aims to explore the potential involvement of long noncoding RNAs(lncRNAs)in mediating the anabolic effects of intermittent PTH and contributing to cementum repair,as identifying lncRNA-disease associations can provide valuable insights for disease diagnosis and ***,we showed that intermittent PTH regulates cell proliferation and mineralization in immortalized murine cementoblast OCCM-30 via the regulation of the Wnt *** vivo,daily administration of PTH is sufficient to accelerate root regeneration by locally inhibiting Wnt/β-catenin *** RNA microarray analysis,lncRNA LITTIP(LGR6 intergenic transcript under intermittent PTH)is identified as a key regulator of cementogenesis under intermittent *** isolation by RNA purification(ChIRP)and RNA immunoprecipitation(RIP)assays revealed that LITTIP binds to mRNA of leucine-rich repeatcontaining G-protein coupled receptor 6(LGR6)and heterogeneous nuclear ribonucleoprotein K(HnRNPK)*** cotransfection experiments confirmed that LITTIP plays a structural role in the formation of the LITTIP/Lgr6/HnRNPK ***,LITTIP is able to promote the expression of LGR6 via the RNA-binding protein ***,our results indicate that the intermittent PTH administration accelerates root regeneration via inhibiting Wnt *** lncRNA LITTIP is identified to negatively regulate cementogenesis,which activates Wnt/β-catenin signaling via high expression of LGR6 promoted by HnRNPK.

关键词： involvement diagnosis cement

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metagenomics analysis identifies oral Streptococcus as potential biomarkers for nasopharyngeal carcinoma

引用

Journal of Genetics and Genomics 2024年第3期51卷 363-366页

作者： Yanmin Liu Chengtao Wang Lixiang Xie Shuling Du Li Ding Ying Cui Runzhi Chen Jingxiang Zhang Wan Wang Xi Liu Yan Wang Shiyan Chen Tian Tan Qiaochu Zhao Limei Yin Chunwei Li Yong Chen Tao Ding Department of Immunology and Microbiology Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510080China Key Laboratory of Tropical Disease Control(Sun Yat-sen university) Ministry of EducationGuangzhouGuangdong 510080China Department of Radiation Oncology The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510080China Department of Infectious Diseases The Fifth Affiliated HospitalSun Yat-sen UniversityZhuhaiGuangdong 519000China Department of Endocrinology&Metabolism The Fifth Affiliated HospitalSun Yat-sen UniversityZhuhaiGuangdong 519000China Department of Otolaryngology The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510080China

Nasopharyngeal carcinoma(NPC)is a malignancy originating from the nasopharyngeal epithelial *** some studies have identified potential biomarkers for early diagnosis of NPC based on metabolomics data(Chen et al.,2023;Zhou et al.,2023)and Epstein-Barr virus subtypes(Xu et al.,2019),their effectiveness and applicability need further investigation,particularly when consideringthe roles of oral microbiota.

关键词： al. nasopharyngeal diagnosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Herb induced liver injury by Xianling Gubao Tablets: A case assessed for causality using updated RUCAM and integrated evidence chain

引用

Chinese Herbal medicines 2024年第2期16卷 301-309页

作者： Chunyu Li Yingying Li Zhaofang Bai Jiabo Wang Guohui Li Xiaohe Xiao National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Senior Department of Hepatology The Fifth Medical Center of PLA General HospitalBeijing 100039China School of Traditional Chinese medicine Capital Medicinal UniversityBeijing 100069China

Objective:A typical case of Xianling Gubao(XLGB)Tablets-induced liver injury was systematically studied in the clinic and the ***:A patient with herb-induced liver injury(HILI)and a history of taking XLGB Tablets before disease onset was engaged as the study subject,and the case was diagnosed according to the updated Roussel Uclaf Causality Assessment Method(RUCAM)and the integrated evidence chain(iEC)method recommended by the Guidelines for diagnosis and Treatment of Herb-induced Liver Injury(HILI Guidelines).Results:Clinical history,biochemical indexes and imaging tests were used to exclude the influence of fundamental diseases and confusing liver diseases such as viral,alcoholic and autoimmune liver diseases on the *** on an investigation of the patient’s medication history,she was suspected to have HILI caused by XLGB Tablets,as the patient was only taking an oral preparation of XLGB Tablets,and the influence of other drugs on the diagnosis was *** patient with alanine aminotransferase(ALT)3 upper limit of normal(ULN)and a calculated R of 6 was diagnosed with possible acute drug-induced hepatocellular *** relationship was considered“highly probable”(score of 9)using the updated RUCAM of ***,the fingerprint similarity between the preparation taken by the patient and a commercially available preparation was 0.99,suggesting that the patient was consuming XLGB Tablets rather than another ***-MS technology and the Agilent Fake TCM-Drugs database were used to investigate the drug,and no chemical additions were *** of the drug for pesticide residues,heavy metals,aflatoxins and other exogenous substances indicated compliance with the content limits of the Chinese ***:In summary,the final diagnosis of XLGB-induced liver injury reached the clinical diagnosis of HILI and was acute severe hepatocellular injury type by the updated RUCAM and ***,this study provides scientif

关键词： chemical analysis compound preparations of traditional chinese medicines integrated evidence chain liver injury Roussel Uclaf Causality Assessment Method Xianling Gubao Tablets

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cleidocranial dysplasia with a rare mutation:Study of a family with review of literature

引用

Open Journal of Stomatology 2013年第8期3卷 402-410页

作者： Ahmet Ercan Sekerci Burhan Balta Oguzhan Bahadir Yildiray Sisman Munis Dundar Turgut Tursem Tokmak Stefan Mundlos Department of oral diagnosis and Radiology Faculty of DentistryErciyes UniversityKayseriTurkey Department of Medical Genetics Faculty of MedicineErciyes UniversityKayseriTurkey Department of Radiodiagnostics Faculty of MedicineErciyes UniversityKayseriTurkey Institute of Medical Genetics Charité-UniversitaetsmedizinBerlinGermany

Introduction: The present study was aimed at advancing the understanding of the pathogenesis of cleidocranial dysplasia (CCD) by presenting a case study based on history, physical examination, typical radiological features, and molecular analysis and a review of the literature. Methods: This study began with a 23-year-old boy (proband) who was referred to the department of oral and maxillofacial radiology with chief complaint of the upper-left first molar tooth and routine dental examination. While evaluating the panoramic radiograph, the patient had approximately 57 teeth in his both of the jaws. Clinical, radiographical and molecular features of the proband, two siblings and their parents were examined and then, DNA analysis was performed. Results: Overall, we present 3 CCD patients with a mutation in the VWRPY motif. The deletion of c. 1754_1757 delTTTG (NM_001024630.2) is determined and it leads to a frame shift mutation and stop codon, p. V585Gfs56X. Conclusions: The present study emphasized the importance of further clinical and molecular investigation when even a single case of CCD is identified within a family. This is the first study performed in Turkey about a family with a mutation in the VWRPY motif. Genotype-phenotype association studies in individuals with CCD are necessary to provide important insights into molecular mechanisms associated with this disease.

关键词： Cleidocranial Dysplasia Mutation RUNX2 Gene Impacted Supernumeraries

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prevention and Treatment of “Epidemic Toxin, Pathogenic Dampness, and Lung Deficiency” after COVID-19 Recovery Based on the Theory of “Preventive Treatment of Diseases” in Traditional Chinese medicine

引用

Chinese medicine and Culture 2019年第3期2卷 181-188页

作者： Jing Ai Linguangjin Wu Ting Wang Wanli Deng Xiaotian Zhang 李欣薇(翻译) Center for Preventive Treatment of Disease Shuguang HospitalShanghai University ot Traditional Chinese Medicine Center for Preventive Treatment of Disease Institute of Characteristic Diagnosis and Treatment TechnologyShanghai Institute of Traditional Chinese Medicine Department of Oncology Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghaiChina 不详

Due to the sequelae and recurrence in patients with COVID-19 after *** article,based on lire theory of“preventive treatment of diseases”in traditional Chinese medicine,winch believes that the three pathogenic factors of epidemic toxin,dampness,and lung deficiency are the fundamental causes of the recurrence of *** treatment strategies are to remove pathogenic factors,strengthen qi,nourish yin,clear heat,moisten dryness,and at the same time,reinforce the lung,spleen and kidney,and soothe the *** a variety of treatments such as oral administration,external treatment,and skin absorption,it provides a new idea and method for the management of the recurrence of COVID-19.

关键词： COVID-19 pathogenesis preventive treatment of diseases recurrence prevention therapeutic principle

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Platelet factor 4 induces bone loss by inhibiting the integrinα5-FAK-ERK pathway

引用

Animal Models and Experimental medicine 2023年第6期6卷 573-584页

作者： Wei Li Qiwei Zhang Ranli Gu Lijun Zeng Hao Liu Department of oral Pathology Peking University School and Hospital of StomatologyNational Center for StomatologyNational Clinical Research Center for Oral DiseasesNational Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing Key Laboratory of Digital StomatologyNational Health Commission Key Laboratory of Digital Technology of StomatologyPeking UniversityBeijingChina Research Unit of Precision Pathologic diagnosis in Tumors of the oral and Maxillofacial Regions Chinese Academy of Medical SciencesBeijingChina Department of Orthopedics Beijing Hospital and National Center of Gerontology and Institute of Geriatrics MedicineChinese Academy of Medical SciencesBeijingChina Department of Orthopedics Beijing Eden HospitalBeijingChina Department of Prosthodontics Peking University School and Hospital of StomatologyNational Center for StomatologyNational Clinical Research Center for Oral DiseasesNational Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing Key Laboratory of Digital StomatologyNational Health Commission Key Laboratory of Digital Technology of StomatologyPeking UniversityBeijingChina The Central Laboratory Peking University School and Hospital of StomatologyNational Center for StomatologyNational Clinical Research Center for Oral DiseasesNational Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing Key Laboratory of Digital StomatologyNational Health Commission Key Laboratory of Digital Technology of StomatologyPeking UniversityBeijingChina

Background:The effect of platelet factor 4(PF4)on bone marrow mesenchymal stem cells(BMMSCs)and osteoporosis is poorly ***,this study aimed to evaluate the effects of PF4-triggered bone destruction in mice and determine the underlying ***:First,in vitro cell proliferation and cell cycle of BMMSCs were assessed using a CCK8 assay and flow cytometry,*** differentiation was confirmed using staining and quantification of alkaline phosphatase and Alizarin Red ***,an osteoporotic mouse model was established by performing bilateral ovariectomy(OVX).Furthermore,the PF4 concentrations were obtained using enzymelinked immunosorbent *** bone microarchitecture of the femur was evaluated using microCT and histological ***,the key regulators of osteogenesis and pathways were investigated using quantitative real-time polymerase chain reaction and Western ***:Human PF4 widely and moderately decreased the cell proliferation and osteogenic differentiation ability of ***,the levels of PF4 in the serum and bone marrow were generally increased,whereas bone microarchitecture deteriorated due to ***,in vivo mouse PF4 supplementation triggered bone deterioration of the *** addition,several key regulators of osteogenesis were downregulated,and the integrinα5-focal adhesion kinase-extracellular signalregulated kinase(ITGA5-FAK-ERK)pathway was inhibited due to PF4 ***:PF4 may be attributed to OVX-i nduced bone loss triggered by the suppression of bone formation in vivo and alleviate BMMSC osteogenic differentiation by inhibiting the ITGA5-FAK-ERK pathway.

关键词： bone loss bone marrow mesenchymal stem cells integrinα5 osteogenesis platelet factor 4

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

NADPH oxidase-1 deficiency offers little protection in Salmonella typhimurium-induced typhlitis in mice

引用

World Journal of Gastroenterology 2016年第46期22卷 10158-10165页

作者： Fong-Fong Chu R Steven Esworthy James H Doroshow Binghui Shen Department of Gastroenterology and Hepatology The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology Department of Cancer Genetics and Epigenetics Beckman Research Institute of City of Hope Center for Cancer Research and Division of Cancer Treatment and diagnosis National Cancer Institute

AIM To test whether Nox1 plays a role in typhlitis induced by Salmonella enterica serovar Typhimurium(S. Tm) in a mouse *** Eight-week-old male wild-type(WT) and Nox1 knockout(KO) C57BL6/J(B6) mice were administered metronidazole water for 4 d to make them susceptible to S. Tm infection by the oral route. The mice were given plain water and administered with 4 different doses of S. Tm by oral gavage. The mice were followed for another 4 d. From the time of the metronidazole application, the mice were observed twice daily and weighed daily. The ileum, cecum and colon were removed for sampling at the fourth day post-inoculation. Portions of all three tissues were fixed for histology and placed in RNAlater for m RNA/c DNA preparation and quantitative real-time PCR. The contents of the cecum were recovered for estimation of S. Tm *** We found Nox1-knockout(Nox1-KO) mice were not more sensitive to S. Tm colonization and infection than WT B6 mice. This conclusion is based on the following observations:(1) S. Tm-infection induced similar weight loss in Nox1-KO mice compared to WT mice;(2) the same S. Tm CFU was recovered from the cecal content of Nox1-KO and WT mice regardless of the inoculation dose, except the lowest inoculation dose(2 × 106 CFU) for which the Nox1-KO had one-log lower CFU than WT mice;(3) there is no difference in cecal pathology between WT and Nox1-KO groups; and(4) there are no S. Tm infection-induced changes in gene expression levels(IL-1b, TNF-α, and Duox2) between WT and Nox1-KO groups. The Alpi gene expression was more suppressed by S. Tm treatment in WT than the Nox1-KO cecum. CONCLUSION Nox1 does not protect mice from S. Tm colonization. Nox1-KO provides a very minor protective effect against S. Tm infection. Using NOX1-specific inhibitors for colitis therapy should not increase risks in bacterial infection.

关键词： Knockout mouse NADPH Oxidase-1 Salmonella typhimurium Goblet cells Reactive oxygen species

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：