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Wearable ultrasensitive and rapid human physiological monitoring based on microfiber Sagnac interferometer

Science China(Information Sciences) 2024年第3期67卷 281-290页

作者： Xin WANG Hongyou ZHOU Meihua CHEN Yongcheng HE Zhishen ZHANG Jiulin GAN Zhongmin YANG State Key laboratory Luminescent Materials and Devices Institute of Optical Communication MaterialsSpecial Glass Fiber and Device Engineering Technology Research and Development Center of Guangdong ProvinceGuangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesSouth China University of Technology Guangdong-Hong Kong-Macao Joint laboratory for Intelligent Micro-Nano Optoelectronic Technology Foshan University

High-sensitive and fast-responding flexible strain sensors are essential for the smart wearable devices that precisely and dynamically perceive the weak deformations induced by human physiological signals. Here, a flexible strain sensor via polydimethylsiloxane(PDMS)-encapsulated microfiber Sagnac interferometer was designed and prepared for monitoring the human pulse signals and sound vibrations. The sensor achieved a record-breaking sensitivity(gauge factor, GF = 9977) and an extremely low detection limit(0.00025%) due to the strong polarization-dependent coupling effect in the microfiber coupler and the polarization-mixing effect in the Sagnac loop. The relative intensity demodulation method also enabled a fast response time of 10 μs. The wearable pulse measurements were implemented by attaching this flexible strain sensor directly to human skin at various locations and the waveform details were accurately captured. Taking advantage of the ultra-high sensitivity and fast response performance of the prepared sensor, the real-time dynamic acquisition of the underwater weak signal, such as the hydro-acoustic waves with a wide range of 20 Hz–16.86 k Hz, has been demonstrated. These initial results pave the way for a new and innovative category of underwater wearable devices with rapid detection of human physiological signals and weak environmental vibrations.

关键词： flexible strain sensor microfiber Sagnac interferometer underwater detection

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Control of temperature dependent viscosity for manufacturing of Bi-doped active fiber

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International Journal of Extreme Manufacturing 2024年第3期6卷 522-530页

作者： Rui Duan Jingfei Chen Hao Ke Tianxia Wei Ke Zhang Xueliang Li Xu Feng Qiuju Zheng Zhixue He Jianrong Qiu Shifeng Zhou State Key laboratory of Luminescent Materials and Devices School of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510640People’s Republic of China Guangdong Provincial Key laboratory of fiber Laser Materials and Applied Techniques Guangdong Engineering Technology Research and Development Center of Special Optical Fiber Materials and DevicesGuangzhou 510640People’s Republic of China School of Materials Science and Engineering Qilu University of TechnologyJinanPeople’s Republic of China Peng Cheng laboratory Shenzhen 518000People’s Republic of China College of optical Science and Engineering State Key Laboratory of Modern Optical InstrumentationZhejiang UniversityHangzhou 310027People’s Republic of China

Bi-activated photonic materials are promising for various applications in high-capacity telecommunication,tunable laser,and advanced bioimaging and *** various Bi-doped material candidates have been explored,manufacturing of Bi heavily doped fiber with excellent optical activity remains a long-standing ***,a novel viscosity evolutional behavior mediated strategy for manufacturing of Bi-doped active fiber with high dopant solubility is *** intrinsic relation among the evolution of Bi,reaction temperature and viscosity of the glass system is ***,the effective avenue to prevent the undesired deactivation of Bi during fiber drawing by tuning the temperature dependent viscosity evolution is *** applying the strategy,for the first time we demonstrate the success in fabrication of heavily doped Bi active ***,the principal fiber amplifier device is constructed and broadband optical signal amplification is *** findings indicate the effectiveness of the proposed temperature dependent viscosity mediated strategy for developing novel photonic active fiber,and they also demonstrate the great potential for application in the next-generation high-capacity telecommunication system.

关键词： infrared luminescence active fiber optical amplification

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Mid-infrared computational temporal ghost imaging

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Light(Science & Applications) 2024年第6期13卷 1088-1097页

作者： Han Wu Bo Hu Lu Chen Fei Peng Zinan Wang Goery Genty Houkun Liang College of Electronics and Information Engineering Sichuan UniversityChengduSichuan610064China College of Electrical Engineering Sichuan UniversityChengduSichuan610064China Key lab of optical fiber Sensing&Communications University of Electronic Science&Technology of ChinaChengduSichuan611731China laboratory of Photonics Tampere UniversityFI-33014TampereFinland

Ghost imaging in the time domain allows for reconstructing fast temporal objects using a slow *** technique involves correlating random or pre-programmed probing temporal intensity patterns with the integrated signal measured after modulation by the temporal ***,the implementation of temporal ghost imaging necessitates ultrafast detectors or modulators for measuring or pre-programming the probing intensity patterns,which are not available in all spectral regions especially in the mid-infrared ***,we demonstrate a frequency downconversion temporal ghost imaging scheme that enables to extend the operation regime to arbitrary wavelengths regions where fast modulators and detectors are not *** approach modulates a signal with temporal intensity patterns in the near-infrared and transfers the patterns to an idler via difference-frequency generation in a nonlinear crystal at a wavelength where the temporal object can be *** a proof-of-concept,we demonstrate computational temporal ghost imaging in the mid-infrared with operating wavelength that can be tuned from 3.2 to 4.3μ*** scheme is flexible and can be extended to other *** results introduce new possibilities for scan-free pump-probe imaging and the study of ultrafast dynamics in spectral regions where ultrafast modulation or detection is challenging such as the mid-infrared and THz regions.

关键词： ghost Ghost scheme

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Programmable photonic RF filters based on an integrated Fabry-Pérot laser with a saturable absorber

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Chinese Optics Letters 2024年第2期22卷 214-220页

作者：徐真真刘奕彤刘嘉慧王玲孙文韬孙振兴陈向飞 Key laboratory of Intelligent optical Sensing and Manipulation of the Ministry of Education&National laboratory of Solid State Microstructures&College of Engineering and Applied Sciences&Institute of optical Communication Engineering&Nanjing University-Tongding Joint lab for Large-Scale Photonic Integrated Circuits Nanjing UniversityNanjing 210023China

We propose and experimentally demonstrate the programmable photonic radio frequency(RF)filters based on an integrated Fabry-Pérot laser with a saturable absorber(FP-SA).Owing to the high output power and the relative flatness spectrum of the FP-SA laser,only a waveshaper and an erbium-doped fiber amplifier(EDFA)were needed,which can greatly reduce the complexity of the *** sinc filter employed 87 taps,representing a record-high tap number and resulting in a 3-d B bandwidth of 0.27 GHz and a quality factor of ***,Gaussian apodization enabled the out-of-band rejection of the filter to reach 34 d B and the center frequency to be finely tuned over a wide range,spanning from 4 to 14 *** results indicate that the proposed scheme could provide a promising guideline for the photonic RF filters that demand both high reconfigurability and greatly reduced size and complexity.

关键词： microwave filters microwave photonics passively mode-locked laser

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Harnessing sub-comb dynamics in a graphene-sensitized microresonator for gas detection

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Frontiers of Optoelectronics 2024年第2期17卷 11-21页

作者： Yupei Liang Mingyu Liu Fan Tang Yanhong Guo Hao Zhang Shihan Liu Yanping Yang Guangming Zhao Teng Tan Baicheng Yao Key laboratory of optical fiber Sensing and Communications(Ministry of Education) University of Electronic Science and Technology of ChinaChengdu 611731China Institute of Semiconductors Chinese Academy of SciencesBeijing 100083China Engineering Center of Integrated Optoelectronic&Radio Meta-Chips University of Electronic Science and TechnologyChengdu 611731China

Since their inception, frequency combs generated in microresonators, known as microcombs, have sparked significant scientific interests. Among the various applications leveraging microcombs, soliton microcombs are often preferred due to their inherent mode-locking capability. However, this choice introduces additional system complexity because an initialization process is required. Meanwhile, despite the theoretical understanding of the dynamics of other comb states, their practical potential, particularly in applications like sensing where simplicity is valued, remains largely untapped. Here, we demonstrate controllable generation of sub-combs that bypasses the need for accessing bistable regime. And in a graphene-sensitized microresonator, the sub-comb heterodynes produce stable, accurate microwave signals for high-precision gas detection. By exploring the formation dynamics of sub-combs, we achieved 2 MHz harmonic comb-to-comb beat notes with a signal-to-noise ratio (SNR) greater than 50 dB and phase noise as low as – 82 dBc/Hz at 1 MHz offset. The graphene sensitization on the intracavity probes results in exceptional frequency responsiveness to the adsorption of gas molecules on the graphene of microcavity surface, enabling detect limits down to the parts per billion (ppb) level. This synergy between graphene and sub-comb formation dynamics in a microcavity structure showcases the feasibility of utilizing microcombs in an incoherent state prior to soliton locking. It may mark a significant step toward the development of easy-to-operate, systemically simple, compact, and high-performance photonic sensors.

关键词： Microresonator optical frequency comb Graphene Gas sensing

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3D printed multicore fiber-tip discriminative sensor for magnetic field and temperature measurements

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Light(Advanced Manufacturing) 2024年第1期5卷 82-92页

作者： Cong Xiong Caoyuan Wang Ruowei Yu Wei Ji Yu Qin Yichun Shen Wei Chen Ai-Qun Liu Limin Xiao Advanced fiber Devices and Systems Group Key Laboratory of Micro and Nano Photonic Structures(MoE)Key Laboratory for Information Science of Electromagnetic Waves(MoE)Shanghai Engineering Research Center of Ultra-Precision Optical ManufacturingSchool of Information Science and TechnologyFudan UniversityShanghaiChina Zhongtian Technology Advanced Materials Co. Ltd.NantongJiangsuChina Key laboratory of Specialty fiber Optics and optical Access Networks Joint International Research Laboratory of Specialty Fiber Optics and Advanced CommunicationShanghai University.ShanghaiChina Department of Electrical and Electronic Engineering The Hong Kong Polytechnic UniversityHong KongChina

Miniaturized fiber-optic magnetic field sensors have attracted considerable interest owing to their superiorities in anti-electromagnetic interference and ***,the intrinsic thermodynamic properties of the material make temperature cross-sensitivity a challenging problem in terms of sensing accuracy and *** this study,an ultracompact multicore fiber(MCF)tip sensor was designed to discriminatively measure the magnetic field and temperature,which was subsequently evaluated *** novel 3D printed sensing component consists of a bowl-shaped microcantilever and a polymer microfluid-infiltrated microcavity on the end-facet of an MCF,acting as two miniaturized Fabry-Perot *** magnetic sensitivity of the microcantilever was implemented by incorporating an iron micro ball into the microcantilever,and the microfluid-infiltrated microcavity enhanced the capability of highly sensitive temperature *** this tiny fiber-facet device in the two channels of an MCF allows discriminative measurements of the magnetic field and temperature by determining the sensitivity coefficient matrix of two *** device exhibited a high magnetic field intensity sensitivity,approximately 1805.6 pm/mT with a fast response time of~213 ms and a high temperature sensitivity of 160.3 pm/℃.Moreover,the sensor had a low condition number of 11.28,indicating high reliability in two-parameter *** proposed 3D printed MCF-tip probes,which detect multiple signals through multiple channels within a single fiber,can provide an ultracompact,sensitive,and reliable scheme for discriminative *** bowl-shaped microcantilever also provides a useful platform for incorporating microstructures with functional materials,extending multi-parameter sensing scenarios and promoting the application of MCFs.

关键词： Two-photon polymerization Multicore fiber-tip sensor Magnetic field sensing Discriminative sensing

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Single-step-etched ultra-compact metamaterial grating coupler enabled by a hierarchical inverse design approach

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 119-126页

作者： Qiao Wang Ruiqi Luo Nan Liu Maojing Hou Bo Xiong Guandong Liu Wei Ma Intelligent Network Research Institute Zhejiang LabHangzhou 311100China State Key laboratory of Modern optical Instrumentation College of Information Science and Electronic EngineeringZhejiang UniversityHangzhou 310027China

With the concept of metamaterials introduced into integrated photonics,subwavelength structures have gained popularity for their ability to create devices with ultra-compact size,high performance,and versatile ***,traditional metamaterial design methods are usually based on empirical templates and physical approximations,lacking the ability to design free-form metamaterial structures and optimize entire devices *** this work,we propose a hierarchical inverse design approach that combines a conventional effective refractive index based metamaterial structures design with a follow-up global topology *** empirical metamaterial grating coupler design based on effective refractive index engineering faces inaccurate index extraction and insufficient approximation of wavevector matching conditions,which deteriorates coupling efficiency,especially for fully-etched devices with the decreased tapering ***,a subsequent overall topology optimization step can well compensate for the negative effect of the shrinking device footprint to increase the efficiency of the metamaterial grating *** demonstrate a 23μm×10μm ultra-compact metamaterial grating coupler with single-stepetched to couple light between a fiber and a 500 nm single-mode silicon waveguide in the *** measurement shows an insertion loss of 3.17 dB and a 3 dB bandwidth of 77 nm,making it the smallest footprint device ever reported.

关键词： waveguide hierarchical inverse

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Suppression of modulation-induced polarization error in spliceless open-loop fiber optic gyroscope [Invited]

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Chinese Optics Letters 2024年第7期22卷 6-11页

作者： Lin Chen Peitong He Biqiang Jiang Jianlin Zhao Key laboratory of Light Field Manipulation and Information Acquisition and Shaanxi Key Laboratory of Optical Information TechnologySchool of Physical Science and TechnologyNorthwestern Polytechnical UniversityXi’an 710129China Zhejiang lab Hangzhou 311100China

The suppression of polarization cross talk in lead zirconate titanate phase modulators as a key error source has been challenging for open-loop fiber optic gyroscopes(FOGs).We developed a polarization-diversity optical frequency domain reflectometry(OFDR)to measure the distributed modulation polarization error in the *** error contributes 8×10^(−6) rad to FOG’s bias *** a UV-fabricated in-fiberλ/4 wave plate and polarization-mode converter with fiber taper technology,the modulation error has been suppressed by 15 dB in assembled *** approach reduced error with temperature from 25°/h to 0.7°/h,meeting the requirements of control-level gyroscopes with bias errors less than 1°/h.

关键词： fiber optic gyroscope inline wave plate optical frequency domain reflectometry polarization-mode converter.

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3D bioprinting of in vitro porous hepatoma models:establishment,evaluation,and anticancer drug testing

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Bio-Design and Manufacturing 2024年第2期7卷 137-152页

作者： Xiaoyuan Wang Zixian Liu Qianqian Duan Boye Zhang Yanyan Cao Zhizhong Shen Meng Li Yanfeng Xi Jianming Wang Shengbo Sang Shanxi Key laboratory of Micro Nano sensors and Artificial Intelligence Perception College of Electronic Information and Optical EngineeringTaiyuan University of TechnologyTaiyuan 030024China Key lab of Advanced Transducers and Intelligent Control System of the Ministry of Education Taiyuan University of TechnologyTaiyuan 030024China Shanxi Institute of 6D Artificial Intelligence Biomedical Science Taiyuan 030031China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030024China Department of Pathology Shanxi Provincial Cancer HospitalTaiyuan 030024China General Hospital of Taiyuan Iron and Steel Company Taiyuan 030809China

Traditional tumor models do not tend to accurately simulate tumor growth in vitro or enable personalized treatment and are particularly unable to discover more beneficial targeted *** address this,this study describes the use of threedimensional(3D)bioprinting technology to construct a 3D model with human hepatocarcinoma SMMC-7721 cells(3DP-7721)by combining gelatin methacrylate(GelMA)and poly(ethylene oxide)(PEO)as two immiscible aqueous phases to form a bioink and innovatively applying fluorescent carbon quantum dots for long-term tracking of *** GelMA(10%,mass fraction)and PEO(1.6%,mass fraction)hydrogel with 3:1 volume ratio offered distinct pore-forming characteristics,satisfactorymechanical properties,and biocompatibility for the creation of the 3DP-7721 *** analysis and quantitative real-time fluorescence polymerase chain reaction(PCR)were used to evaluate the biological properties of the *** with the two-dimensional culture cell model(2D-7721)and the 3D mixed culture cell model(3DM-7721),3DP-7721 significantly improved the proliferation of cells and expression of tumor-related proteins and ***,we evaluated the differences between the three culture models and the effectiveness of antitumor drugs in the three models and discovered that the efficacy of antitumor drugs varied because of significant differences in resistance proteins and genes between the three *** addition,the comparison of tumor formation in the three models found that the cells cultured by the 3DP-7721 model had strong tumorigenicity in nude *** evaluation of the levels of biochemical indicators related to the formation of solid tumors showed that the 3DP-7721 model group exhibited pathological characteristics of malignant tumors,the generated solid tumors were similar to actual tumors,and the deterioration was *** research therefore acts as a foundation for the application of 3DP-7721 models in drug devel

关键词： 3D bioprinting Hepatoma tumor models Drug screening Antitumor drug development

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Stackelberg Game for Wireless Powered and Backscattering Enabled Sensor Networks

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China Communications 2024年第3期21卷 189-204页

作者： Lyu Bin Cao Yi Wang Shuai Guo Haiyan Hao Chengyao Key laboratory of Ministry of Education in Broadband Wireless Communication and Sensor Network Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China Jiangsu Engineering Research Center of Novel optical fiber Technology and Communication Network Suzhou 215006China Guangdong-Hong Kong-Macao Joint laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

This paper investigates a wireless powered and backscattering enabled sensor network based on the non-linear energy harvesting model, where the power beacon(PB) delivers energy signals to wireless sensors to enable their passive backscattering and active transmission to the access point(AP). We propose an efficient time scheduling scheme for network performance enhancement, based on which each sensor can always harvest energy from the PB over the entire block except its time slots allocated for passive and active information delivery. Considering the PB and wireless sensors are from two selfish service providers, we use the Stackelberg game to model the energy interaction among them. To address the non-convexity of the leader-level problem, we propose to decompose the original problem into two subproblems and solve them iteratively in an alternating manner. Specifically, the successive convex approximation, semi-definite relaxation(SDR) and variable substitution techniques are applied to find a nearoptimal solution. To evaluate the performance loss caused by the interaction between two providers, we further investigate the social welfare maximization problem. Numerical results demonstrate that compared to the benchmark schemes, the proposed scheme can achieve up to 35.4% and 38.7% utility gain for the leader and the follower, respectively.

关键词： backscatter communication energy interaction stackelberg game wireless powered sensor network

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